PSU Profiles
Keywords
Last Name
Institution

Laurence Demers

TitleProfessor Emeritus
InstitutionCollege of Medicine
DepartmentPathology
Address500 University Drive Hershey PA 17033
Mailbox: H158
Phone7175318316

 Overview 
 overview
PREFERRED TITLE/ROLE:

Distinguished Professor Emeritus of Pathology and Medicine

EDUCATION:

Ph.D., SUNY - Upstate Medical Center, 1970
Residency, Harvard Medical School
Fellowship, University of Oxford

NARRATIVE:

Biomarkers and Metabolic Bone Disease

We have been interested in the effects of bone disease as well as metastatic disease to bone on biomarkers of bone remodeling. We have established specific biochemical assays to monitor bone resorption and bone formation that include bone collagen breakdown products, markers of bone collagen synthesis, markers of osteoclastogenesis and markers of osteoblast function and secretion. These biomarkers have been evaluated in patients with osteoporosis, Paget's disease and skeletal metastases treated with pharmaceutical agents that can attenuate bone turnover and inhibit bone loss or resorption. These agents include the bisphosphonate class of compounds as well as hormone replacement therapy used to treated bone resorption caused by bone disease.


 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Walter KN, Corwin EJ, Ulbrecht J, Demers LM, Bennett JM, Whetzel CA, Klein LC. Elevated thyroid stimulating hormone is associated with elevated cortisol in healthy young men and women. Thyroid Res. 2012; 5(1):13.
    View in: PubMed
  2. Coney P, Demers LM, Dodson WC, Kunselman AR, Ladson G, Legro RS. Determination of vitamin D in relation to body mass index and race in a defined population of black and white women. Int J Gynaecol Obstet. 2012 Oct; 119(1):21-5.
    View in: PubMed
  3. Signori C, DuBrock C, Richie JP, Prokopczyk B, Demers LM, Hamilton C, Hartman TJ, Liao J, El-Bayoumy K, Manni A. Administration of omega-3 fatty acids and Raloxifene to women at high risk of breast cancer: interim feasibility and biomarkers analysis from a clinical trial. Eur J Clin Nutr. 2012 Aug; 66(8):878-84.
    View in: PubMed
  4. Engler-Chiurazzi EB, Talboom JS, Braden BB, Tsang CW, Mennenga S, Andrews M, Demers LM, Bimonte-Nelson HA. Continuous estrone treatment impairs spatial memory and does not impact number of basal forebrain cholinergic neurons in the surgically menopausal middle-aged rat. Horm Behav. 2012 Jun; 62(1):1-9.
    View in: PubMed
  5. Lipton A, Chapman JA, Demers L, Shepherd LE, Han L, Wilson CF, Pritchard KI, Leitzel KE, Ali SM, Pollak M. Elevated bone turnover predicts for bone metastasis in postmenopausal breast cancer: results of NCIC CTG MA.14. J Clin Oncol. 2011 Sep 20; 29(27):3605-10.
    View in: PubMed
  6. Manni A, Xu H, Washington S, Aliaga C, Das A, Cooper T, Richie JP, Prokopczyk B, Calcagnotto A, Trushin N, Van den Heuvel JP, Hamilton C, Demers LM, Liao J, Verderame MF, El-Bayoumy K. The effects of Tamoxifen and fish oil on mammary carcinogenesis in polyoma middle T transgenic mice. Horm Cancer. 2011 Aug; 2(4):249-59.
    View in: PubMed
  7. Ladson G, Dodson WC, Sweet SD, Archibong AE, Kunselman AR, Demers LM, Williams NI, Coney P, Legro RS. Racial influence on the polycystic ovary syndrome phenotype: a black and white case-control study. Fertil Steril. 2011 Jul; 96(1):224-229.e2.
    View in: PubMed
  8. Ladson G, Dodson WC, Sweet SD, Archibong AE, Kunselman AR, Demers LM, Lee PA, Williams NI, Coney P, Legro RS. Effects of metformin in adolescents with polycystic ovary syndrome undertaking lifestyle therapy: a pilot randomized double-blind study. Fertil Steril. 2011 Jun 30; 95(8):2595-8.e1-6.
    View in: PubMed
  9. Witherby S, Johnson J, Demers L, Mount S, Littenberg B, Maclean CD, Wood M, Muss H. Topical testosterone for breast cancer patients with vaginal atrophy related to aromatase inhibitors: a phase I/II study. Oncologist. 2011; 16(4):424-31.
    View in: PubMed
  10. Ladson G, Dodson WC, Sweet SD, Archibong AE, Kunselman AR, Demers LM, Williams NI, Coney P, Legro RS. The effects of metformin with lifestyle therapy in polycystic ovary syndrome: a randomized double-blind study. Fertil Steril. 2011 Mar 1; 95(3):1059-66.e1-7.
    View in: PubMed
  11. Raja-Khan N, Kunselman AR, Hogeman CS, Stetter CM, Demers LM, Legro RS. Effects of atorvastatin on vascular function, inflammation, and androgens in women with polycystic ovary syndrome: a double-blind, randomized, placebo-controlled trial. Fertil Steril. 2011 Apr; 95(5):1849-52.
    View in: PubMed
  12. Raja-Khan N, Shuja SA, Kunselman AR, Hogeman CS, Demers LM, Gnatuk CL, Legro RS. Brachial artery conductance during reactive hyperemia is increased in women with polycystic ovary syndrome. Eur J Obstet Gynecol Reprod Biol. 2011 Mar; 155(1):49-53.
    View in: PubMed
  13. Raja-Khan N, Kunselman AR, Demers LM, Ewens KG, Spielman RS, Legro RS. A variant in the fibrillin-3 gene is associated with TGF-ß and inhibin B levels in women with polycystic ovary syndrome. Fertil Steril. 2010 Dec; 94(7):2916-9.
    View in: PubMed
  14. Molife LR, Fong PC, Paccagnella L, Reid AH, Shaw HM, Vidal L, Arkenau HT, Karavasilis V, Yap TA, Olmos D, Spicer J, Postel-Vinay S, Yin D, Lipton A, Demers L, Leitzel K, Gualberto A, de Bono JS. The insulin-like growth factor-I receptor inhibitor figitumumab (CP-751,871) in combination with docetaxel in patients with advanced solid tumours: results of a phase Ib dose-escalation, open-label study. Br J Cancer. 2010 Jul 27; 103(3):332-9.
    View in: PubMed
  15. Demers LM. Androgen deficiency in women; role of accurate testosterone measurements. Maturitas. 2010 Sep; 67(1):39-45.
    View in: PubMed
  16. Lipton A, Campbell-Baird C, Harvey H, Kim C, Demers L, Costa L. Phase I trial of zoledronic acid + imatinib mesylate (Gleevec) in patients with bone metastases. Am J Clin Oncol. 2010 Feb; 33(1):75-8.
    View in: PubMed
  17. Karp DD, Pollak MN, Cohen RB, Eisenberg PD, Haluska P, Yin D, Lipton A, Demers L, Leitzel K, Hixon ML, Terstappen LW, Garland L, Paz-Ares LG, Cardenal F, Langer CJ, Gualberto A. Safety, pharmacokinetics, and pharmacodynamics of the insulin-like growth factor type 1 receptor inhibitor figitumumab (CP-751,871) in combination with paclitaxel and carboplatin. J Thorac Oncol. 2009 Nov; 4(11):1397-403.
    View in: PubMed
  18. Vo MN, Evans M, Leitzel K, Ali SM, Wilson M, Demers L, Evans DB, Lipton A. Elevated plasma endoglin (CD105) predicts decreased response and survival in a metastatic breast cancer trial of hormone therapy. Breast Cancer Res Treat. 2010 Feb; 119(3):767-71.
    View in: PubMed
  19. Acosta JI, Mayer L, Talboom JS, Zay C, Scheldrup M, Castillo J, Demers LM, Enders CK, Bimonte-Nelson HA. Premarin improves memory, prevents scopolamine-induced amnesia and increases number of basal forebrain choline acetyltransferase positive cells in middle-aged surgically menopausal rats. Horm Behav. 2009 Mar; 55(3):454-64.
    View in: PubMed
  20. Demers LM. Testosterone and estradiol assays: current and future trends. Steroids. 2008 Dec 12; 73(13):1333-8.
    View in: PubMed
  21. Lipton A, Leitzel K, Chaudri-Ross HA, Evans DB, Ali SM, Demers L, Hamer P, Brown-Shimer S, Pierce K, Gaur V, Carney W. Serum TIMP-1 and response to the aromatase inhibitor letrozole versus tamoxifen in metastatic breast cancer. J Clin Oncol. 2008 Jun 1; 26(16):2653-8.
    View in: PubMed
  22. Erickson DR, Tomaszewski JE, Kunselman AR, Stetter CM, Peters KM, Rovner ES, Demers LM, Wheeler MA, Keay SK. Urine markers do not predict biopsy findings or presence of bladder ulcers in interstitial cystitis/painful bladder syndrome. J Urol. 2008 May; 179(5):1850-6.
    View in: PubMed
  23. Katcher HI, Kunselman AR, Dmitrovic R, Demers LM, Gnatuk CL, Kris-Etherton PM, Legro RS. Comparison of hormonal and metabolic markers after a high-fat, Western meal versus a low-fat, high-fiber meal in women with polycystic ovary syndrome. Fertil Steril. 2009 Apr; 91(4):1175-82.
    View in: PubMed
  24. Pauli EM, Legro RS, Demers LM, Kunselman AR, Dodson WC, Lee PA. Diminished paternity and gonadal function with increasing obesity in men. Fertil Steril. 2008 Aug; 90(2):346-51.
    View in: PubMed
  25. Kent SC, Gnatuk CL, Kunselman AR, Demers LM, Lee PA, Legro RS. Hyperandrogenism and hyperinsulinism in children of women with polycystic ovary syndrome: a controlled study. J Clin Endocrinol Metab. 2008 May; 93(5):1662-9.
    View in: PubMed
  26. Katcher HI, Legro RS, Kunselman AR, Gillies PJ, Demers LM, Bagshaw DM, Kris-Etherton PM. The effects of a whole grain-enriched hypocaloric diet on cardiovascular disease risk factors in men and women with metabolic syndrome. Am J Clin Nutr. 2008 Jan; 87(1):79-90.
    View in: PubMed
  27. Legro RS, Pauli JG, Kunselman AR, Meadows JW, Kesner JS, Zaino RJ, Demers LM, Gnatuk CL, Dodson WC. Effects of continuous versus cyclical oral contraception: a randomized controlled trial. J Clin Endocrinol Metab. 2008 Feb; 93(2):420-9.
    View in: PubMed
  28. Ryan CW, Huo D, Bylow K, Demers LM, Stadler WM, Henderson TO, Vogelzang NJ. Suppression of bone density loss and bone turnover in patients with hormone-sensitive prostate cancer and receiving zoledronic acid. BJU Int. 2007 Jul; 100(1):70-5.
    View in: PubMed
  29. Park H, Aiyar SE, Fan P, Wang J, Yue W, Okouneva T, Cox C, Jordan MA, Demers L, Cho H, Kim S, Song RX, Santen RJ. Effects of tetramethoxystilbene on hormone-resistant breast cancer cells: biological and biochemical mechanisms of action. Cancer Res. 2007 Jun 15; 67(12):5717-26.
    View in: PubMed
  30. Lipton A, Ali SM, Leitzel K, Demers L, Evans DB, Hamer P, Brown-Shimer S, Pierce K, Carney W. Elevated plasma tissue inhibitor of metalloproteinase-1 level predicts decreased response and survival in metastatic breast cancer. Cancer. 2007 May 15; 109(10):1933-9.
    View in: PubMed
  31. Legro RS, Zaino RJ, Demers LM, Kunselman AR, Gnatuk CL, Williams NI, Dodson WC. The effects of metformin and rosiglitazone, alone and in combination, on the ovary and endometrium in polycystic ovary syndrome. Am J Obstet Gynecol. 2007 Apr; 196(4):402.e1-10; discussion 402.e10-1.
    View in: PubMed
  32. Jun JY, Griffith JW, Bruggeman R, Washington S, Demers LM, Verderame MF, Manni A. Effects of polyamine depletion by alpha-difluoromethylornithine on in vitro and in vivo biological properties of 4T1 murine mammary cancer cells. Breast Cancer Res Treat. 2008 Jan; 107(1):33-40.
    View in: PubMed
  33. Erickson DR, Kunselman AR, Bentley CM, Peters KM, Rovner ES, Demers LM, Wheeler MA, Keay SK. Changes in urine markers and symptoms after bladder distention for interstitial cystitis. J Urol. 2007 Feb; 177(2):556-60.
    View in: PubMed
  34. Jun JY, Griffith JW, Bruggeman R, Washington S, Demers LM, Verderame MF, Manni A. Effects of polyamine depletion by alpha-difluoromethylornithine on in vitro and in vivo biological properties of 4T1 murine mammary cancer cells. Breast Cancer Res Treat. 2007 Sep; 105(1):29-36.
    View in: PubMed
  35. Souder C, Leitzel K, Ali SM, Demers L, Evans DB, Chaudri-Ross HA, Hackl W, Hamer P, Carney W, Lipton A. Serum epidermal growth factor receptor/HER-2 predicts poor survival in patients with metastatic breast cancer. Cancer. 2006 Nov 15; 107(10):2337-45.
    View in: PubMed
  36. Ryan CW, Huo D, Demers LM, Beer TM, Lacerna LV. Zoledronic acid initiated during the first year of androgen deprivation therapy increases bone mineral density in patients with prostate cancer. J Urol. 2006 Sep; 176(3):972-8; discussion 978.
    View in: PubMed
  37. Donahue SW, Galley SA, Vaughan MR, Patterson-Buckendahl P, Demers LM, Vance JL, McGee ME. Parathyroid hormone may maintain bone formation in hibernating black bears (Ursus americanus) to prevent disuse osteoporosis. J Exp Biol. 2006 May; 209(Pt 9):1630-8.
    View in: PubMed
  38. Theriault RL, Biermann JS, Brown E, Brufsky A, Demers L, Grewal RK, Guise T, Jackson R, McEnery K, Podoloff D, Ravdin P, Shapiro CL, Smith M, Van Poznak CH. NCCN Task Force Report: Bone Health and Cancer Care. J Natl Compr Canc Netw. 2006 May; 4 Suppl 2:S1-20; quiz S21-2.
    View in: PubMed
  39. Richert MM, Phadke PA, Matters G, DiGirolamo DJ, Washington S, Demers LM, Bond JS, Manni A, Welch DR. Metastasis of hormone-independent breast cancer to lung and bone is decreased by alpha-difluoromethylornithine treatment. Breast Cancer Res. 2005; 7(5):R819-27.
    View in: PubMed
  40. Zhang Y, Lu Y, Yuan BZ, Castranova V, Shi X, Stauffer JL, Demers LM, Chen F. The Human mineral dust-induced gene, mdig, is a cell growth regulating gene associated with lung cancer. Oncogene. 2005 Jul 21; 24(31):4873-82.
    View in: PubMed
  41. Lipton A, Leitzel K, Ali SM, Demers L, Harvey HA, Chaudri-Ross HA, Evans D, Lang R, Hackl W, Hamer P, Carney W. Serum HER-2/neu conversion to positive at the time of disease progression in patients with breast carcinoma on hormone therapy. Cancer. 2005 Jul 15; 104(2):257-63.
    View in: PubMed
  42. McNulty PH, King N, Scott S, Hartman G, McCann J, Kozak M, Chambers CE, Demers LM, Sinoway LI. Effects of supplemental oxygen administration on coronary blood flow in patients undergoing cardiac catheterization. Am J Physiol Heart Circ Physiol. 2005 Mar; 288(3):H1057-62.
    View in: PubMed
  43. Erickson DR, Tomaszewski JE, Kunselman AR, Bentley CM, Peters KM, Rovner ES, Demers LM, Wheeler MA, Keay SK. Do the National Institute of Diabetes and Digestive and Kidney Diseases cystoscopic criteria associate with other clinical and objective features of interstitial cystitis? J Urol. 2005 Jan; 173(1):93-7.
    View in: PubMed
  44. Manni A, Washington S, Hu X, Griffith JW, Bruggeman R, Demers LM, Mauger D, Verderame MF. Effects of polyamine synthesis inhibitors on primary tumor features and metastatic capacity of human breast cancer cells. Clin Exp Metastasis. 2005; 22(3):255-63.
    View in: PubMed
  45. Hu X, Washington S, Verderame MF, Demers LM, Mauger D, Manni A. Biological activity of the S-adenosylmethionine decarboxylase inhibitor SAM486A in human breast cancer cells in vitro and in vivo. Int J Oncol. 2004 Dec; 25(6):1831-8.
    View in: PubMed
  46. Erickson DR, Kunselman AR, Bentley CM, Peters KM, Rovner ES, Demers LM, Tomaszewski JE. Is urine methylhistamine a useful marker for interstitial cystitis? J Urol. 2004 Dec; 172(6 Pt 1):2256-60.
    View in: PubMed
  47. Wang S, Paris F, Sultan CS, Song RX, Demers LM, Sundaram B, Settlage J, Ohorodnik S, Santen RJ. Recombinant cell ultrasensitive bioassay for measurement of estrogens in postmenopausal women. J Clin Endocrinol Metab. 2005 Mar; 90(3):1407-13.
    View in: PubMed
  48. Whipple TJ, Le BH, Demers LM, Chinchilli VM, Petit MA, Sharkey N, Williams NI. Acute effects of moderate intensity resistance exercise on bone cell activity. Int J Sports Med. 2004 Oct; 25(7):496-501.
    View in: PubMed
  49. Ito RK, Demers LM. Pharmacogenomics and pharmacogenetics: future role of molecular diagnostics in the clinical diagnostic laboratory. Clin Chem. 2004 Sep; 50(9):1526-7.
    View in: PubMed
  50. Stamets K, Taylor DS, Kunselman A, Demers LM, Pelkman CL, Legro RS. A randomized trial of the effects of two types of short-term hypocaloric diets on weight loss in women with polycystic ovary syndrome. Fertil Steril. 2004 Mar; 81(3):630-7.
    View in: PubMed
  51. Ali SM, Demers LM, Leitzel K, Harvey HA, Clemens D, Mallinak N, Engle L, Chinchilli V, Costa L, Brady C, Seaman J, Lipton A. Baseline serum NTx levels are prognostic in metastatic breast cancer patients with bone-only metastasis. Ann Oncol. 2004 Mar; 15(3):455-9.
    View in: PubMed
  52. Demers LM. Thyroid disease: pathophysiology and diagnosis. Clin Lab Med. 2004 Mar; 24(1):19-28.
    View in: PubMed
  53. Wang C, Catlin DH, Demers LM, Starcevic B, Swerdloff RS. Measurement of total serum testosterone in adult men: comparison of current laboratory methods versus liquid chromatography-tandem mass spectrometry. J Clin Endocrinol Metab. 2004 Feb; 89(2):534-43.
    View in: PubMed
  54. Donahue SW, Vaughan MR, Demers LM, Donahue HJ. Bone formation is not impaired by hibernation (disuse) in black bears Ursus americanus. J Exp Biol. 2003 Dec; 206(Pt 23):4233-9.
    View in: PubMed
  55. Demers LM, Costa L, Lipton A. Biochemical markers and skeletal metastases. Clin Orthop Relat Res. 2003 Oct; (415 Suppl):S138-47.
    View in: PubMed
  56. Lipton A, Ali SM, Leitzel K, Demers L, Harvey HA, Chaudri-Ross HA, Brady C, Wyld P, Carney W. Serum HER-2/neu and response to the aromatase inhibitor letrozole versus tamoxifen. J Clin Oncol. 2003 May 15; 21(10):1967-72.
    View in: PubMed
  57. Perry PJ, Kutscher EC, Lund BC, Yates WR, Holman TL, Demers L. Measures of aggression and mood changes in male weightlifters with and without androgenic anabolic steroid use. J Forensic Sci. 2003 May; 48(3):646-51.
    View in: PubMed
  58. Donahue SW, Vaughan MR, Demers LM, Donahue HJ. Serum markers of bone metabolism show bone loss in hibernating bears. Clin Orthop Relat Res. 2003 Mar; (408):295-301.
    View in: PubMed
  59. Demers LM, Spencer CA. Laboratory medicine practice guidelines: laboratory support for the diagnosis and monitoring of thyroid disease. Clin Endocrinol (Oxf). 2003 Feb; 58(2):138-40.
    View in: PubMed
  60. Demers LM. Bone markers in the management of patients with skeletal metastases. Cancer. 2003 Feb 1; 97(3 Suppl):874-9.
    View in: PubMed
  61. Demers LM. Andropause: an androgen deficiency state in the ageing male. Expert Opin Pharmacother. 2003 Feb; 4(2):183-90.
    View in: PubMed
  62. Manni A, Washington S, Craig L, Cloud M, Griffith JW, Verderame MF, Texter LJ, Mauger D, Demers LM, Harms JF, Welch DR. Effects of alpha-difluoromethylornithine on local recurrence and pulmonary metastasis from MDA-MB-435 breast cancer xenografts in nude mice. Clin Exp Metastasis. 2003; 20(4):321-5.
    View in: PubMed
  63. De Souza MJ, Van Heest J, Demers LM, Lasley BL. Luteal phase deficiency in recreational runners: evidence for a hypometabolic state. J Clin Endocrinol Metab. 2003 Jan; 88(1):337-46.
    View in: PubMed
  64. Baloch Z, Carayon P, Conte-Devolx B, Demers LM, Feldt-Rasmussen U, Henry JF, LiVosli VA, Niccoli-Sire P, John R, Ruf J, Smyth PP, Spencer CA, Stockigt JR. Laboratory medicine practice guidelines. Laboratory support for the diagnosis and monitoring of thyroid disease. Thyroid. 2003 Jan; 13(1):3-126.
    View in: PubMed
  65. Legro RS, Lin HM, Demers LM, Lloyd T. Urinary free cortisol increases in adolescent caucasian females during perimenarche. J Clin Endocrinol Metab. 2003 Jan; 88(1):215-9.
    View in: PubMed
  66. Whipple T, Sharkey N, Demers L, Williams N. Leptin and the skeleton. Clin Endocrinol (Oxf). 2002 Dec; 57(6):701-11.
    View in: PubMed
  67. Ali SM, Leitzel K, Chinchilli VM, Engle L, Demers L, Harvey HA, Carney W, Allard JW, Lipton A. Relationship of serum HER-2/neu and serum CA 15-3 in patients with metastatic breast cancer. Clin Chem. 2002 Aug; 48(8):1314-20.
    View in: PubMed
  68. Chen F, Demers LM, Shi X. Upstream signal transduction of NF-kappaB activation. Curr Drug Targets Inflamm Allergy. 2002 Jun; 1(2):137-49.
    View in: PubMed
  69. Lipton A, Ali SM, Leitzel K, Demers L, Chinchilli V, Engle L, Harvey HA, Brady C, Nalin CM, Dugan M, Carney W, Allard J. Elevated serum Her-2/neu level predicts decreased response to hormone therapy in metastatic breast cancer. J Clin Oncol. 2002 Mar 15; 20(6):1467-72.
    View in: PubMed
  70. Liben LS, Susman EJ, Finkelstein JW, Chinchilli VM, Kunselman S, Schwab J, Dubas JS, Demers LM, Lookingbill G, Darcangelo MR, Krogh HR, Kulin HE. The effects of sex steroids on spatial performance: a review and an experimental clinical investigation. Dev Psychol. 2002 Mar; 38(2):236-53.
    View in: PubMed
  71. Holman JW, Mifflin TE, Felder RA, Demers LM. Evaluation of an automated preanalytical robotic workstation at two academic health centers. Clin Chem. 2002 Mar; 48(3):540-8.
    View in: PubMed
  72. Costa L, Demers LM, Gouveia-Oliveira A, Schaller J, Costa EB, de Moura MC, Lipton A. Prospective evaluation of the peptide-bound collagen type I cross-links N-telopeptide and C-telopeptide in predicting bone metastases status. J Clin Oncol. 2002 Feb 1; 20(3):850-6.
    View in: PubMed
  73. Vesper HW, Demers LM, Eastell R, Garnero P, Kleerekoper M, Robins SP, Srivastava AK, Warnick GR, Watts NB, Myers GL. Assessment and recommendations on factors contributing to preanalytical variability of urinary pyridinoline and deoxypyridinoline. Clin Chem. 2002 Feb; 48(2):220-35.
    View in: PubMed
  74. Manni A, Washington S, Griffith JW, Verderame MF, Mauger D, Demers LM, Samant RS, Welch DR. Influence of polyamines on in vitro and in vivo features of aggressive and metastatic behavior by human breast cancer cells. Clin Exp Metastasis. 2002; 19(2):95-105.
    View in: PubMed
  75. Lloyd T, Lin HM, Eggli DF, Dodson WC, Demers LM, Legro RS. Adolescent Caucasian mothers have reduced adult hip bone density. Fertil Steril. 2002 Jan; 77(1):136-40.
    View in: PubMed
  76. Yue W, Berstein LM, Wang JP, Clark GM, Hamilton CJ, Demers LM, Santen RJ. The potential role of estrogen in aromatase regulation in the breast. J Steroid Biochem Mol Biol. 2001 Dec; 79(1-5):157-64.
    View in: PubMed
  77. Schwab J, Kulin HE, Susman EJ, Finkelstein JW, Chinchilli VM, Kunselman SJ, Liben LS, D'Arcangelo MR, Demers LM. The role of sex hormone replacement therapy on self-perceived competence in adolescents with delayed puberty. Child Dev. 2001 Sep-Oct; 72(5):1439-50.
    View in: PubMed
  78. Lipton A, Costa L, Ali S, Demers L. Use of markers of bone turnover for monitoring bone metastases and the response to therapy. Semin Oncol. 2001 Aug; 28(4 Suppl 11):54-9.
    View in: PubMed
  79. Manni A, Fischer S, Franks M, Washington S, De Arment R, Griffith J, Demers L, Verderame M, Leiby B, Mauger D. S-adenosylmethionine decarboxylase overexpression reduces invasiveness and tumorigenicity in nude mice of MCF-7 breast cancer cells. Int J Oncol. 2001 Aug; 19(2):317-23.
    View in: PubMed
  80. Manni A, Trout D, Verderame MF, Washington S, Mauger D, Demers L. Effect of alpha-difluoromethyl-ornithine on the expression and function of the epidermal growth factor receptor in human breast epithelial cells in culture. Breast Cancer Res Treat. 2001 Jul; 68(2):139-46.
    View in: PubMed
  81. Lipton A, Costa L, Ali SM, Demers LM. Bone markers in the management of metastatic bone disease. Cancer Treat Rev. 2001 Jun; 27(3):181-5.
    View in: PubMed
  82. Perry PJ, Lund BC, Arndt S, Holman T, Bever-Stille KA, Paulsen J, Demers LM. Bioavailable testosterone as a correlate of cognition, psychological status, quality of life, and sexual function in aging males: implications for testosterone replacement therapy. Ann Clin Psychiatry. 2001 Jun; 13(2):75-80.
    View in: PubMed
  83. Chen F, Demers LM, Vallyathan V, Lu Y, Castranova V, Shi X. Impairment of NF-kappaB activation and modulation of gene expression by calpastatin. Am J Physiol Cell Physiol. 2000 Sep; 279(3):C709-16.
    View in: PubMed
  84. Demers LM, Costa L, Lipton A. Biochemical markers and skeletal metastases. Cancer. 2000 Jun 15; 88(12 Suppl):2919-26.
    View in: PubMed
  85. Legro RS, Lin HM, Demers LM, Lloyd T. Rapid maturation of the reproductive axis during perimenarche independent of body composition. J Clin Endocrinol Metab. 2000 Mar; 85(3):1021-5.
    View in: PubMed
  86. Jefcoate CR, Liehr JG, Santen RJ, Sutter TR, Yager JD, Yue W, Santner SJ, Tekmal R, Demers L, Pauley R, Naftolin F, Mor G, Berstein L. Tissue-specific synthesis and oxidative metabolism of estrogens. J Natl Cancer Inst Monogr. 2000; (27):95-112.
    View in: PubMed
  87. Chen F, Demers LM, Vallyathan V, Lu Y, Castranova V, Shi X. Involvement of 5'-flanking kappaB-like sites within bcl-x gene in silica-induced Bcl-x expression. J Biol Chem. 1999 Dec 10; 274(50):35591-5.
    View in: PubMed
  88. Finkelstein JW, D'Arcangelo MR, Susman EJ, Chinchilli VM, Kunselman SJ, Schwab J, Demers LM, Liben LS, Kulin HE. Self-assessment of physical sexual maturation in boys and girls with delayed puberty. J Adolesc Health. 1999 Dec; 25(6):379-81.
    View in: PubMed
  89. O'Shaughnessy JA, Demers LM, Jones SE, Arseneau J, Khandelwal P, George T, Gersh R, Mauger D, Manni A. Alpha-difluoromethylornithine as treatment for metastatic breast cancer patients. Clin Cancer Res. 1999 Nov; 5(11):3438-44.
    View in: PubMed
  90. Veldhuis JD, Iranmanesh A, Demers LM, Mulligan T. Joint basal and pulsatile hypersecretory mechanisms drive the monotropic follicle-stimulating hormone (FSH) elevation in healthy older men: concurrent preservation of the orderliness of the FSH release process: a general clinical research center study. J Clin Endocrinol Metab. 1999 Oct; 84(10):3506-14.
    View in: PubMed
  91. Demers LM, Smith B. Application of the MediSense precision-G blood glucose testing system in a neonatal intensive care unit. Clin Chem. 1999 Sep; 45(9):1578-9.
    View in: PubMed
  92. Demers LM. Biochemical markers in the management of patients with metastatic bone disease. Clin Chem. 1999 Aug; 45(8 Pt 1):1131-2.
    View in: PubMed
  93. Chen F, Demers LM, Vallyathan V, Ding M, Lu Y, Castranova V, Shi X. Vanadate induction of NF-kappaB involves IkappaB kinase beta and SAPK/ERK kinase 1 in macrophages. J Biol Chem. 1999 Jul 16; 274(29):20307-12.
    View in: PubMed
  94. Good C, Tulchinsky M, Mauger D, Demers LM, Legro RS. Bone mineral density and body composition in lean women with polycystic ovary syndrome. Fertil Steril. 1999 Jul; 72(1):21-5.
    View in: PubMed
  95. Chen F, Lu Y, Castranova V, Rojanasakul Y, Miyahara K, Shizuta Y, Vallyathan V, Shi X, Demers LM. Nitric oxide inhibits HIV tat-induced NF-kappaB activation. Am J Pathol. 1999 Jul; 155(1):275-84.
    View in: PubMed
  96. Yue W, Santen RJ, Wang JP, Hamilton CJ, Demers LM. Aromatase within the breast. Endocr Relat Cancer. 1999 Jun; 6(2):157-64.
    View in: PubMed
  97. Chen F, Castranova V, Shi X, Demers LM. New insights into the role of nuclear factor-kappaB, a ubiquitous transcription factor in the initiation of diseases. Clin Chem. 1999 Jan; 45(1):7-17.
    View in: PubMed
  98. Costa LA, Kopreski MS, Demers LM, Chinchilli VM, Santen RJ, Harvey HA, Lipton A. Effect of the potent aromatase inhibitor fadrozole hydrochloride (CGS 16949A) in postmenopausal women with breast carcinoma. Cancer. 1999 Jan 1; 85(1):100-3.
    View in: PubMed
  99. Lipton A, Demers L, Curley E, Chinchilli V, Gaydos L, Hortobagyi G, Theriault R, Clemens D, Costa L, Seaman J, Knight R. Markers of bone resorption in patients treated with pamidronate. Eur J Cancer. 1998 Dec; 34(13):2021-6.
    View in: PubMed
  100. Smith SM, Nillen JL, Leblanc A, Lipton A, Demers LM, Lane HW, Leach CS. Collagen cross-link excretion during space flight and bed rest. J Clin Endocrinol Metab. 1998 Oct; 83(10):3584-91.
    View in: PubMed
  101. Susman EJ, Finkelstein JW, Chinchilli VM, Schwab J, Liben LS, D'Arcangelo MR, Meinke J, Demers LM, Lookingbill G, Kulin HE. The effect of sex hormone replacement therapy on behavior problems and moods in adolescents with delayed puberty. J Pediatr. 1998 Oct; 133(4):521-5.
    View in: PubMed
  102. Finkelstein JW, Susman EJ, Chinchilli VM, D'Arcangelo MR, Kunselman SJ, Schwab J, Demers LM, Liben LS, Kulin HE. Effects of estrogen or testosterone on self-reported sexual responses and behaviors in hypogonadal adolescents. J Clin Endocrinol Metab. 1998 Jul; 83(7):2281-5.
    View in: PubMed
  103. Santner SJ, Albertson B, Zhang GY, Zhang GH, Santulli M, Wang C, Demers LM, Shackleton C, Santen RJ. Comparative rates of androgen production and metabolism in Caucasian and Chinese subjects. J Clin Endocrinol Metab. 1998 Jun; 83(6):2104-9.
    View in: PubMed
  104. Yue W, Wang JP, Hamilton CJ, Demers LM, Santen RJ. In situ aromatization enhances breast tumor estradiol levels and cellular proliferation. Cancer Res. 1998 Mar 1; 58(5):927-32.
    View in: PubMed
  105. Sinha S, Kaseta J, Santner SJ, Demers LM, Bremmer WJ, Santen RJ. Effect of CGS 20267 on ovarian aromatase and gonadotropin levels in the rat. Breast Cancer Res Treat. 1998 Mar; 48(1):45-51.
    View in: PubMed
  106. Yue W, Santner SJ, Masamura S, Wang JP, Demers LM, Hamilton C, Santen RJ. Determinants of tissue estradiol levels and biologic responsiveness in breast tumors. Breast Cancer Res Treat. 1998; 49 Suppl 1:S1-7; discussion S33-7.
    View in: PubMed
  107. Chen F, Lu Y, Demers LM, Rojanasakul Y, Shi X, Vallyathan V, Castranova V. Role of hydroxyl radical in silica-induced NF-kappa B activation in macrophages. Ann Clin Lab Sci. 1998 Jan-Feb; 28(1):1-13.
    View in: PubMed
  108. Finkelstein JW, Susman EJ, Chinchilli VM, Kunselman SJ, D'Arcangelo MR, Schwab J, Demers LM, Liben LS, Lookingbill G, Kulin HE. Estrogen or testosterone increases self-reported aggressive behaviors in hypogonadal adolescents. J Clin Endocrinol Metab. 1997 Aug; 82(8):2433-8.
    View in: PubMed
  109. Kulin HE, Finkelstein JW, D'Arcangelo MR, Susman EJ, Chinchilli V, Kunselman S, Schwab J, Demers L, Lookingbill G. Diversity of pubertal testosterone changes in boys with constitutional delay in growth and/or adolescence. J Pediatr Endocrinol Metab. 1997 Jul-Aug; 10(4):395-400.
    View in: PubMed
  110. Chen F, Lu Y, Kuhn DC, Maki M, Shi X, Sun SC, Demers LM. Calpain contributes to silica-induced I kappa B-alpha degradation and nuclear factor-kappa B activation. Arch Biochem Biophys. 1997 Jun 15; 342(2):383-8.
    View in: PubMed
  111. Santen RJ, Santner SJ, Pauley RJ, Tait L, Kaseta J, Demers LM, Hamilton C, Yue W, Wang JP. Estrogen production via the aromatase enzyme in breast carcinoma: which cell type is responsible? J Steroid Biochem Mol Biol. 1997 Apr; 61(3-6):267-71.
    View in: PubMed
  112. Chen F, Sun S, Kuhn DC, Gaydos LJ, Shi X, Lu Y, Demers LM. Involvement of NF-kappaB in silica-induced cyclooxygenase II gene expression in rat alveolar macrophages. Am J Physiol. 1997 Apr; 272(4 Pt 1):L779-86.
    View in: PubMed
  113. Chen F, Sun S, Kuhn DC, Lu Y, Gaydos LJ, Shi X, Demers LM. Tetrandrine inhibits signal-induced NF-kappa B activation in rat alveolar macrophages. Biochem Biophys Res Commun. 1997 Feb 3; 231(1):99-102.
    View in: PubMed
  114. Manni A, Wechter R, Gilmour S, Verderame MF, Mauger D, Demers LM. Ornithine decarboxylase over-expression stimulates mitogen-activated protein kinase and anchorage-independent growth of human breast epithelial cells. Int J Cancer. 1997 Jan 17; 70(2):175-82.
    View in: PubMed
  115. Demers LM. Clinical usefulness of markers of bone degradation and formation. Scand J Clin Lab Invest Suppl. 1997; 227:12-20.
    View in: PubMed
  116. Manni A, Buckwalter E, Etindi R, Kunselman S, Rossini A, Mauger D, Dabbs D, Demers L. Induction of a less aggressive breast cancer phenotype by protein kinase C-alpha and -beta overexpression. Cell Growth Differ. 1996 Sep; 7(9):1187-98.
    View in: PubMed
  117. Kopreski MS, Witters L, Brennan WA, Buckwalter EA, Chinchilli VM, Demers LM, Lipton A. Protein tyrosine kinase activity in breast cancer and its relation to prognostic indicators. Anticancer Res. 1996 Sep-Oct; 16(5B):3037-41.
    View in: PubMed
  118. Volas GH, Leitzel K, Teramoto Y, Grossberg H, Demers L, Lipton A. Serial serum c-erbB-2 levels in patients with breast carcinoma. Cancer. 1996 Jul 15; 78(2):267-72.
    View in: PubMed
  119. Chen F, Kuhn DC, Gaydos LJ, Demers LM. Induction of nitric oxide and nitric oxide synthase mRNA by silica and lipopolysaccharide in PMA-primed THP-1 cells. APMIS. 1996 Mar; 104(3):176-82.
    View in: PubMed
  120. Watterberg KL, Demers LM, Scott SM, Murphy S. Chorioamnionitis and early lung inflammation in infants in whom bronchopulmonary dysplasia develops. Pediatrics. 1996 Feb; 97(2):210-5.
    View in: PubMed
  121. Lloyd T, Martel JK, Rollings N, Andon MB, Kulin H, Demers LM, Eggli DF, Kieselhorst K, Chinchilli VM. The effect of calcium supplementation and Tanner stage on bone density, content and area in teenage women. Osteoporos Int. 1996; 6(4):276-83.
    View in: PubMed
  122. Lipton A, Costa L, Demers LM. Bone markers in osteoporosis and malignancy. Can J Oncol. 1995 Dec; 5 Suppl 1:11-5.
    View in: PubMed
  123. Demers LM, Costa L, Chinchilli VM, Gaydos L, Curley E, Lipton A. Biochemical markers of bone turnover in patients with metastatic bone disease. Clin Chem. 1995 Oct; 41(10):1489-94.
    View in: PubMed
  124. Chen F, Sun SC, Kuh DC, Gaydos LJ, Demers LM. Essential role of NF-kappa B activation in silica-induced inflammatory mediator production in macrophages. Biochem Biophys Res Commun. 1995 Sep 25; 214(3):985-92.
    View in: PubMed
  125. Chen F, Kuhn DC, Sun SC, Gaydos LJ, Demers LM. Dependence and reversal of nitric oxide production on NF-kappa B in silica and lipopolysaccharide-induced macrophages. Biochem Biophys Res Commun. 1995 Sep 25; 214(3):839-46.
    View in: PubMed
  126. Kuhn DC, Stauffer JL, Gaydos LJ, Demers LM. Inflammatory and fibrotic mediator release by alveolar macrophages from coal miners. J Toxicol Environ Health. 1995 Sep; 46(1):9-21.
    View in: PubMed
  127. Klein KO, Demers LM, Santner SJ, Baron J, Cutler GB, Santen RJ. Use of ultrasensitive recombinant cell bioassay to measure estrogen levels in women with breast cancer receiving the aromatase inhibitor, letrozole. J Clin Endocrinol Metab. 1995 Sep; 80(9):2658-60.
    View in: PubMed
  128. Manni A, Badger B, Grove R, Kunselman S, Demers L. Isolation and characterization of human breast cancer cells overexpressing S-adenosylmethionine decarboxylase. Cancer Lett. 1995 Aug 16; 95(1-2):23-8.
    View in: PubMed
  129. Manni A, Badger B, Wechter R, Kunselman S, Rossini A, Demers L. Biochemical and growth-modulatory effects of the new S-adenosylmethionine decarboxylase inhibitor CGP 48664 in malignant and immortalized normal human breast epithelial cells in culture. Int J Cancer. 1995 Aug 9; 62(4):485-91.
    View in: PubMed
  130. Kuhn DC, Demers LM. Effect of surfactant on basal and silica-induced eicosanoid production by the alveolar macrophage. Am J Physiol. 1995 Aug; 269(2 Pt 1):L165-70.
    View in: PubMed
  131. Rosano TG, Demers LM, Hillam R, Dybas MT, Leinung M. Clinical and analytical evaluation of an immunoradiometric assay for corticotropin. Clin Chem. 1995 Jul; 41(7):1022-7.
    View in: PubMed
  132. Plourde PV, Dyroff M, Dowsett M, Demers L, Yates R, Webster A. ARIMIDEX: a new oral, once-a-day aromatase inhibitor. J Steroid Biochem Mol Biol. 1995 Jun; 53(1-6):175-9.
    View in: PubMed
  133. Leitzel K, Teramoto Y, Konrad K, Chinchilli VM, Volas G, Grossberg H, Harvey H, Demers L, Lipton A. Elevated serum c-erbB-2 antigen levels and decreased response to hormone therapy of breast cancer. J Clin Oncol. 1995 May; 13(5):1129-35.
    View in: PubMed
  134. Lipton A, Demers LM, Harvey HA, Kambic KB, Grossberg H, Brady C, Adlercruetz H, Trunet PF, Santen RJ. Letrozole (CGS 20267). A phase I study of a new potent oral aromatase inhibitor of breast cancer. Cancer. 1995 Apr 15; 75(8):2132-8.
    View in: PubMed
  135. Manni A, Wechter R, Grove R, Wei L, Martel J, Demers L. Polyamine profiles and growth properties of ornithine decarboxylase overexpressing MCF-7 breast cancer cells in culture. Breast Cancer Res Treat. 1995 Apr; 34(1):45-53.
    View in: PubMed
  136. Manni A, Wechter R, Wei L, Heitjan D, Demers L. Phenotypic features of breast cancer cells overexpressing ornithine-decarboxylase. J Cell Physiol. 1995 Apr; 163(1):129-36.
    View in: PubMed
  137. LeBlanc A, Schneider V, Spector E, Evans H, Rowe R, Lane H, Demers L, Lipton A. Calcium absorption, endogenous excretion, and endocrine changes during and after long-term bed rest. Bone. 1995 Apr; 16(4 Suppl):301S-304S.
    View in: PubMed
  138. Baker ER, Best RG, Manfredi RL, Demers LM, Wolf GC. Efficacy of progesterone vaginal suppositories in alleviation of nervous symptoms in patients with premenstrual syndrome. J Assist Reprod Genet. 1995 Mar; 12(3):205-9.
    View in: PubMed
  139. Masamura S, Adlercreutz H, Harvey H, Lipton A, Demers LM, Santen RJ, Santner SJ. Aromatase inhibitor development for treatment of breast cancer. Breast Cancer Res Treat. 1995; 33(1):19-26.
    View in: PubMed
  140. Vesell ES, Chambers CE, Seaton TD, Passananti GT, Demers LM, Beyer KH. Pyrazinoylguanidine downregulates the glucose fatty-acid cycle in hypertensive, hyperinsulinemic diabetic patients. J Clin Pharmacol. 1994 Dec; 34(12):1234-45.
    View in: PubMed
  141. Demers LM, Kuhn DC. Influence of mineral dusts on metabolism of arachidonic acid by alveolar macrophage. Environ Health Perspect. 1994 Dec; 102 Suppl 10:97-100.
    View in: PubMed
  142. Demers LM, Kleerekoper M. Recent advances in biochemical markers of bone turnover. Clin Chem. 1994 Nov; 40(11 Pt 1):1994-5.
    View in: PubMed
  143. Faulkner WR, Demers LM. Importance of age-dependent reference values in biochemical testing: are we including the elderly population? Clin Chem. 1994 Jun; 40(6):855-6.
    View in: PubMed
  144. Kulin H, Demers L, Chinchilli V, Martel J, Stevens L. Usefulness of sequential urinary follicle-stimulating hormone and luteinizing hormone measurements in the diagnosis of adolescent hypogonadotropism in males. J Clin Endocrinol Metab. 1994 May; 78(5):1208-11.
    View in: PubMed
  145. De Souza MJ, Luciano AA, Arce JC, Demers LM, Loucks AB. Clinical tests explain blunted cortisol responsiveness but not mild hypercortisolism in amenorrheic runners. J Appl Physiol (1985). 1994 Mar; 76(3):1302-9.
    View in: PubMed
  146. Demers LM. Effects of Fadrozole (CGS 16949A) and Letrozole (CGS 20267) on the inhibition of aromatase activity in breast cancer patients. Breast Cancer Res Treat. 1994; 30(1):95-102.
    View in: PubMed
  147. Cherouny PH, Pankuch GA, Romero R, Botti JJ, Kuhn DC, Demers LM, Appelbaum PC. Neutrophil attractant/activating peptide-1/interleukin-8: association with histologic chorioamnionitis, preterm delivery, and bioactive amniotic fluid leukoattractants. Am J Obstet Gynecol. 1993 Nov; 169(5):1299-303.
    View in: PubMed
  148. Xu LH, Koch KL, Summy-Long J, Stern RM, Seaton JF, Harrison TS, Demers LM, Bingaman S. Hypothalamic and gastric myoelectrical responses during vection-induced nausea in healthy Chinese subjects. Am J Physiol. 1993 Oct; 265(4 Pt 1):E578-84.
    View in: PubMed
  149. Wei LL, Leach MW, Miner RS, Demers LM. Evidence for progesterone receptors in human osteoblast-like cells. Biochem Biophys Res Commun. 1993 Sep 15; 195(2):525-32.
    View in: PubMed
  150. Kuhn DC, Stauffer JL, Gaydos LJ, Lacey SL, Demers LM. An inhibitor of thromboxane production attenuates tumor necrosis factor release by activated human alveolar macrophages. Prostaglandins. 1993 Sep; 46(3):195-205.
    View in: PubMed
  151. Vesell ES, Chambers CE, Passananti GT, Demers LM, Beyer KH. Effects of pyrazinoylguanidine on the glucose-fatty acid cycle in normal subjects and patients with non-insulin-dependent diabetes mellitus. J Clin Pharmacol. 1993 Sep; 33(9):823-31.
    View in: PubMed
  152. Kuhn DC, Griffith JW, Stauffer JL, Riling S, Demers LM. Characterization of alveolar macrophage eicosanoid production in a non-human primate model of mineral dust exposure. Prostaglandins. 1993 Sep; 46(3):207-20.
    View in: PubMed
  153. Lloyd T, Andon MB, Rollings N, Martel JK, Landis JR, Demers LM, Eggli DF, Kieselhorst K, Kulin HE. Calcium supplementation and bone mineral density in adolescent girls. JAMA. 1993 Aug 18; 270(7):841-4.
    View in: PubMed
  154. Lipton A, Demers L, Daniloff Y, Curley E, Hamilton C, Harvey H, Witters L, Seaman J, Van der Giessen R, Seyedin S. Increased urinary excretion of pyridinium cross-links in cancer patients. Clin Chem. 1993 Apr; 39(4):614-8.
    View in: PubMed
  155. Demers LM, Lipton A, Harvey HA, Hanagan J, Mulagha M, Santen RJ. The effects of long term fadrozole hydrochloride treatment in patients with advanced stage breast cancer. J Steroid Biochem Mol Biol. 1993 Mar; 44(4-6):683-5.
    View in: PubMed
  156. Smith JP, Kramer ST, Demers LM. Effects of gastrin and difluoromethylornithine on growth of human colon cancer. Dig Dis Sci. 1993 Mar; 38(3):520-8.
    View in: PubMed
  157. Demers LM, Lipton A, Harvey HA, Kambic KB, Grossberg H, Brady C, Santen RJ. The efficacy of CGS 20267 in suppressing estrogen biosynthesis in patients with advanced stage breast cancer. J Steroid Biochem Mol Biol. 1993 Mar; 44(4-6):687-91.
    View in: PubMed
  158. Demers LM. A rapid, automated method for glycohemoglobin. Clin Chem. 1993 Feb; 39(2):363.
    View in: PubMed
  159. Finkelman RD, Bell NH, Strong DD, Demers LM, Baylink DJ. Ovariectomy selectively reduces the concentration of transforming growth factor beta in rat bone: implications for estrogen deficiency-associated bone loss. Proc Natl Acad Sci U S A. 1992 Dec 15; 89(24):12190-3.
    View in: PubMed
  160. Demers LM. New biochemical marker for bone disease: is it a breakthrough? Clin Chem. 1992 Nov; 38(11):2169-70.
    View in: PubMed
  161. Manni A, Khin S, Biser N, English H, Badger B, Martel J, Demers L. Synchronization of breast cancer cell proliferation in vivo by combined hormonal and polyamine manipulation. Cancer Res. 1992 Oct 15; 52(20):5720-4.
    View in: PubMed
  162. Manni A, Badger B, Martel J, Demers L. Role of polyamines in the growth of hormone-responsive and -resistant human breast cancer cells in nude mice. Cancer Lett. 1992 Sep 14; 66(1):1-9.
    View in: PubMed
  163. Leitzel K, Teramoto Y, Sampson E, Mauceri J, Langton BC, Demers L, Podczaski E, Harvey H, Shambaugh S, Volas G, et al. Elevated soluble c-erbB-2 antigen levels in the serum and effusions of a proportion of breast cancer patients. J Clin Oncol. 1992 Sep; 10(9):1436-43.
    View in: PubMed
  164. Hoagland MH, Hafer LJ, Demers LM. CA-549 is not diagnostically useful as an immunohistochemical marker for breast carcinoma. Arch Pathol Lab Med. 1992 Sep; 116(9):938-42.
    View in: PubMed
  165. Lloyd T, Rollings N, Andon MB, Demers LM, Eggli DF, Kieselhorst K, Kulin H, Landis JR, Martel JK, Orr G, et al. Determinants of bone density in young women. I. Relationships among pubertal development, total body bone mass, and total body bone density in premenarchal females. J Clin Endocrinol Metab. 1992 Aug; 75(2):383-7.
    View in: PubMed
  166. Kuhn DC, Demers LM. Influence of mineral dust surface chemistry on eicosanoid production by the alveolar macrophage. J Toxicol Environ Health. 1992 Jan; 35(1):39-50.
    View in: PubMed
  167. Lloyd T, Schaeffer JM, Walker MA, Demers LM. Urinary hormonal concentrations and spinal bone densities of premenopausal vegetarian and nonvegetarian women. Am J Clin Nutr. 1991 Dec; 54(6):1005-10.
    View in: PubMed
  168. Malarkey WB, Strauss RH, Leizman DJ, Liggett M, Demers LM. Endocrine effects in female weight lifters who self-administer testosterone and anabolic steroids. Am J Obstet Gynecol. 1991 Nov; 165(5 Pt 1):1385-90.
    View in: PubMed
  169. Berne CA, Zubey LA, Demers LM. Interference of serum mercury with the Abbott TDx. Clin Chem. 1991 Sep; 37(9):1659-60.
    View in: PubMed
  170. Wild RA, Demers LM, Applebaum-Bowden D, Lenker R. Hirsutism: metabolic effects of two commonly used oral contraceptives and spironolactone. Contraception. 1991 Aug; 44(2):113-24.
    View in: PubMed
  171. Veldhuis JD, Garmey JC, Urban RJ, Demers LM, Aggarwal BB. Ovarian actions of tumor necrosis factor-alpha (TNF alpha): pleiotropic effects of TNF alpha on differentiated functions of untransformed swine granulosa cells. Endocrinology. 1991 Aug; 129(2):641-8.
    View in: PubMed
  172. Brackett LE, Demers LM, Mamourian AC, Ellenberger C, Santen RJ. Moebius syndrome in association with hypogonadotropic hypogonadism. J Endocrinol Invest. 1991 Jul-Aug; 14(7):599-607.
    View in: PubMed
  173. Santen RJ, Demers LM, Lynch J, Harvey H, Lipton A, Mulagha M, Hanagan J, Garber JE, Henderson IC, Navari RM, et al. Specificity of low dose fadrozole hydrochloride (CGS 16949A) as an aromatase inhibitor. J Clin Endocrinol Metab. 1991 Jul; 73(1):99-106.
    View in: PubMed
  174. Lookingbill DP, Demers LM, Wang C, Leung A, Rittmaster RS, Santen RJ. Clinical and biochemical parameters of androgen action in normal healthy Caucasian versus Chinese subjects. J Clin Endocrinol Metab. 1991 Jun; 72(6):1242-8.
    View in: PubMed
  175. Kim I, Manni A, Lynch J, Demers L. Polyamine involvement in the secretion and action of TGF-alpha in hormone sensitive human breast cancer cells in culture. Breast Cancer Res Treat. 1991 May; 18(2):83-91.
    View in: PubMed
  176. Demers LM. Monoclonal antibodies to lutropin: are our immunoassays too specific? Clin Chem. 1991 Mar; 37(3):311-2.
    View in: PubMed
  177. Pardridge WM, Demers LM. Bioavailable testosterone in salivary glands. Clin Chem. 1991 Feb; 37(2):139-40.
    View in: PubMed
  178. Wild RA, Hirisave V, Bianco A, Podczaski ES, Demers LM. Endometrial antibodies versus CA-125 for the detection of endometriosis. Fertil Steril. 1991 Jan; 55(1):90-4.
    View in: PubMed
  179. Manni A, Badger B, Lynch J, Demers L. Selectivity of polyamine involvement in hormone action on normal and neoplastic target tissues of the rat. Breast Cancer Res Treat. 1991 Jan-Feb; 17(3):187-96.
    View in: PubMed
  180. Manni A, Lancaster S, English H, Badger B, Lynch J, Demers L. Kinetic and morphometric responses of heterogeneous populations of NMU-induced rat mammary tumor cells to hormone and antipolyamine therapy in vivo. Breast Cancer Res Treat. 1991 Jan-Feb; 17(3):179-86.
    View in: PubMed
  181. Manni A, Boucher AE, Demers LM, Harvey HA, Lipton A, Simmonds MA, Bartholomew M. Somatostatin analogues in the treatment of breast and prostate cancer. J Steroid Biochem Mol Biol. 1990 Dec 20; 37(6):1083-7.
    View in: PubMed
  182. Wild RA, Bartholomew M, Applebaum-Bowden D, Demers LM, Hazzard W, Santen RJ. Evidence of heterogeneous mechanisms in lipoprotein lipid alterations in hyperandrogenic women. Am J Obstet Gynecol. 1990 Dec; 163(6 Pt 1):1998-2005.
    View in: PubMed
  183. Manni A, Wright C, Badger B, Lynch J, Demers L. Role of insulin-like growth factor-related peptides in the estradiol-, prolactin-, and progesterone-stimulated growth of N-nitrosomethylurea-induced rat mammary tumors in soft agar. Cancer Res. 1990 Nov 15; 50(22):7179-83.
    View in: PubMed
  184. Kochak GM, Mangat S, Mulagha MT, Entwistle EA, Santen RJ, Lipton A, Demers L. The pharmacodynamic inhibition of estrogen synthesis by fadrozole, an aromatase inhibitor, and its pharmacokinetic disposition. J Clin Endocrinol Metab. 1990 Nov; 71(5):1349-5.
    View in: PubMed
  185. Glikman PL, Manni A, Bartholomew M, Demers L. Polyamine involvement in basal and estradiol-stimulated insulin-like growth factor I secretion and action in breast cancer cells in culture. J Steroid Biochem Mol Biol. 1990 Sep; 37(1):1-10.
    View in: PubMed
  186. Kuhn DC, Botti JJ, Cherouny PH, Demers LM. Eicosanoid production and transfer in the placenta of the diabetic pregnancy. Prostaglandins. 1990 Aug; 40(2):205-15.
    View in: PubMed
  187. Kuhn DC, Crawford MA, Stuart MJ, Botti JJ, Demers LM. Alterations in transfer and lipid distribution of arachidonic acid in placentas of diabetic pregnancies. Diabetes. 1990 Aug; 39(8):914-8.
    View in: PubMed
  188. Simons RJ, Simon JM, Demers LM, Santen RJ. Thyroid dysfunction in elderly hospitalized patients. Effect of age and severity of illness. Arch Intern Med. 1990 Jun; 150(6):1249-53.
    View in: PubMed
  189. Demers LM, Melby JC, Wilson TE, Lipton A, Harvey HA, Santen RJ. The effects of CGS 16949A, an aromatase inhibitor on adrenal mineralocorticoid biosynthesis. J Clin Endocrinol Metab. 1990 Apr; 70(4):1162-6.
    View in: PubMed
  190. Lipton A, Harvey HA, Demers LM, Hanagan JR, Mulagha MT, Kochak GM, Fitzsimmons S, Sanders SI, Santen RJ. A phase I trial of CGS 16949A. A new aromatase inhibitor. Cancer. 1990 Mar 15; 65(6):1279-85.
    View in: PubMed
  191. Manni A, Wright C, Badger B, Bartholomew M, Herlyn M, Mendelsohn J, Masui H, Demers L. Role of transforming growth factor-alpha-related peptides in the autocrine/paracrine control of experimental breast cancer growth in vitro by estradiol, prolactin, and progesterone. Breast Cancer Res Treat. 1990 Feb; 15(2):73-83.
    View in: PubMed
  192. Wild RA, Applebaum-Bowden D, Demers LM, Bartholomew M, Landis JR, Hazzard WR, Santen RJ. Lipoprotein lipids in women with androgen excess: independent associations with increased insulin and androgen. Clin Chem. 1990 Feb; 36(2):283-9.
    View in: PubMed
  193. Koch KL, Stern RM, Vasey MW, Seaton JF, Demers LM, Harrison TS. Neuroendocrine and gastric myoelectrical responses to illusory self-motion in humans. Am J Physiol. 1990 Feb; 258(2 Pt 1):E304-10.
    View in: PubMed
  194. Cohen FJ, Manni A, Glikman P, Bartholomew M, Demers L. Interactions between growth factor secretion and polyamines in MCF-7 breast cancer cells. Eur J Cancer. 1990; 26(5):603-8.
    View in: PubMed
  195. Kauffman GL, Zhang L, Xing LP, Seaton J, Colony P, Demers L. Central neurotensin protects the mucosa by a prostaglandin-mediated mechanism and inhibits gastric acid secretion in the rat. Ann N Y Acad Sci. 1990; 597:175-90.
    View in: PubMed
  196. Aberg JA, Demers LM, Romano PJ, Tenser RB. Prostaglandin production in chronic progressive multiple sclerosis. J Clin Lab Anal. 1990; 4(4):246-50.
    View in: PubMed
  197. Kuhn DC, Stanley CF, el-Ayouby N, Demers LM. Effect of in vivo coal dust exposure on arachidonic acid metabolism in the rat alveolar macrophage. J Toxicol Environ Health. 1990; 29(2):157-68.
    View in: PubMed
  198. Manni A, Boucher AE, Demers LM, Harvey HA, Lipton A, Simmonds MA, Bartholomew M. Endocrine effects of combined somatostatin analog and bromocriptine therapy in women with advanced breast cancer. Breast Cancer Res Treat. 1989 Dec; 14(3):289-98.
    View in: PubMed
  199. Manni A, Badger B, Lynch J, Glikman P, Demers L. Hormonal control of polyamine pools in experimental breast cancer in vivo: correlation with estrogen and progesterone receptor levels. Breast Cancer Res Treat. 1989 Nov; 14(2):227-34.
    View in: PubMed
  200. Zhang L, Xing LP, Demers L, Washington J, Kauffman GL. Central neurotensin inhibits gastric acid secretion: an adrenergic mechanism in rats. Gastroenterology. 1989 Nov; 97(5):1130-4.
    View in: PubMed
  201. Leuenberger PK, Buchanan JR, Myers CA, Lloyd T, Demers LM. Determination of peak trabecular bone density: interplay of dietary fiber, carbohydrate, and androgens. Am J Clin Nutr. 1989 Nov; 50(5):955-61.
    View in: PubMed
  202. Manni A, Badger B, Glikman P, Bartholomew M, Santner S, Demers L. Individual and combined effects of alpha-difluoromethylornithine and ovariectomy on the growth and polyamine milieu of experimental breast cancer in rats. Cancer Res. 1989 Jul 1; 49(13):3529-34.
    View in: PubMed
  203. Veldhuis JD, Demers LM. Mechanism(s) by which activation of protein kinase C is coupled to prostacyclin synthesis in granulosa cells. Mol Cell Endocrinol. 1989 May; 63(1-2):219-26.
    View in: PubMed
  204. Glikman P, Manni A, Demers L, Bartholomew M. Polyamine involvement in the growth of hormone-responsive and -resistant human breast cancer cells in culture. Cancer Res. 1989 Mar 15; 49(6):1371-6.
    View in: PubMed
  205. Kulin HE, Frontera MA, Demers LM, Bartholomew MJ, Lloyd TA. The onset of sperm production in pubertal boys. Relationship to gonadotropin excretion. Am J Dis Child. 1989 Feb; 143(2):190-3.
    View in: PubMed
  206. Santen RJ, Demers LM, Adlercreutz H, Harvey H, Santner S, Sanders S, Lipton A. Inhibition of aromatase with CGS 16949A in postmenopausal women. J Clin Endocrinol Metab. 1989 Jan; 68(1):99-106.
    View in: PubMed
  207. Buchanan JR, Myers C, Lloyd T, Leuenberger P, Demers LM. Determinants of peak trabecular bone density in women: the role of androgens, estrogen, and exercise. J Bone Miner Res. 1988 Dec; 3(6):673-80.
    View in: PubMed
  208. Cohen FJ, Manni A, Glikman P, Bartholomew M, Demers L. Involvement of the polyamine pathway in antiestrogen-induced growth inhibition of human breast cancer. Cancer Res. 1988 Dec 1; 48(23):6819-25.
    View in: PubMed
  209. Buchanan JR, Hospodar P, Myers C, Leuenberger P, Demers LM. Effect of excess endogenous androgens on bone density in young women. J Clin Endocrinol Metab. 1988 Nov; 67(5):937-43.
    View in: PubMed
  210. Lookingbill DP, Egan N, Santen RJ, Demers LM. Correlation of serum 3 alpha-androstanediol glucuronide with acne and chest hair density in men. J Clin Endocrinol Metab. 1988 Nov; 67(5):986-91.
    View in: PubMed
  211. Baker E, Demers L. Menstrual status in female athletes: correlation with reproductive hormones and bone density. Obstet Gynecol. 1988 Nov; 72(5):683-7.
    View in: PubMed
  212. Lloyd T, Myers C, Buchanan JR, Demers LM. Collegiate women athletes with irregular menses during adolescence have decreased bone density. Obstet Gynecol. 1988 Oct; 72(4):639-42.
    View in: PubMed
  213. Manni A, Badger B, Wright C, Glenn J, Ahmed SR, Demers LM. Species-specificity of estradiol regulated growth factors in breast cancer. Eur J Cancer Clin Oncol. 1988 Aug; 24(8):1349-54.
    View in: PubMed
  214. Lancaster S, English HF, Demers LM, Manni A. Kinetic and morphometric responses of heterogeneous populations of experimental breast cancer cells in vivo. Cancer Res. 1988 Jun 1; 48(11):3276-81.
    View in: PubMed
  215. Oaks TE, Myers JL, Magovern JA, Demers LM, Waldhausen JA. The effect of cyclosporine on atrial natriuretic peptide in goats. Transplant Proc. 1988 Jun; 20(3 Suppl 3):549-50.
    View in: PubMed
  216. Manni A, Wright C, Badger B, Demers L, Bartholomew M. Polyamines and autocrine control of N-nitrosomethylurea-induced rat mammary tumor growth in vitro by progesterone. Cancer Res. 1988 Jun 1; 48(11):3058-61.
    View in: PubMed
  217. Lookingbill DP, Demers LM, Tigelaar RE, Shalita AR. Effect of isotretinoin on serum levels of precursor and peripherally derived androgens in patients with acne. Arch Dermatol. 1988 Apr; 124(4):540-3.
    View in: PubMed
  218. Ahmed SR, Boucher AE, Manni A, Santen RJ, Bartholomew M, Demers LM. Transdermal testosterone therapy in the treatment of male hypogonadism. J Clin Endocrinol Metab. 1988 Mar; 66(3):546-51.
    View in: PubMed
  219. Wild RA, Buchanan JR, Myers C, Demers LM. Declining adrenal androgens: an association with bone loss in aging women. Proc Soc Exp Biol Med. 1987 Dec; 186(3):355-60.
    View in: PubMed
  220. Kulin HE, Demers LM, Rogol AD, Veldhuis JD. The effect of long-term opiate antagonist administration to pubertal boys. J Androl. 1987 Nov-Dec; 8(6):374-7.
    View in: PubMed
  221. Manni A, Badger B, Wright C, Ahmed SR, Demers LM. Effects of progestins on growth of experimental breast cancer in culture: interaction with estradiol and prolactin and involvement of the polyamine pathway. Cancer Res. 1987 Jun 15; 47(12):3066-71.
    View in: PubMed
  222. Veldhuis JD, Demers LM. Activation of protein kinase C is coupled to prostaglandin E2 synthesis in swine granulosa cells. Prostaglandins. 1987 Jun; 33(6):819-29.
    View in: PubMed
  223. Wild RA, Buchanan JR, Myers C, Lloyd T, Demers LM. Adrenal androgens, sex-hormone binding globulin and bone density in osteoporotic menopausal women: is there a relationship? Maturitas. 1987 Apr; 9(1):55-61.
    View in: PubMed
  224. Demers LM, Veldhuis JD. A stimulatory role for the protein kinase C pathway in ovarian prostaglandin synthesis: studies with cultured swine granulosa cells. Adv Prostaglandin Thromboxane Leukot Res. 1987; 17B:1117-21.
    View in: PubMed
  225. Demers LM, Boucher AE, Santen RJ. Aminoglutethimide therapy in breast cancer: relationship of blood levels to drug-related side effects. Clin Physiol Biochem. 1987; 5(5):287-91.
    View in: PubMed
  226. Naeye RL, Demers LM. Differing effects of fetal sex on pregnancy and its outcome. Am J Med Genet Suppl. 1987; 3:67-74.
    View in: PubMed
  227. Manni A, Wright C, Luk GD, Davis G, Demers LM. Polyamines and the synthesis of estradiol-regulated growth factors in rat mammary cancer in culture. Breast Cancer Res Treat. 1987; 9(1):45-51.
    View in: PubMed
  228. Veldhuis JD, Demers LM. An inhibitory role for the protein kinase C pathway in ovarian steroidogenesis. Studies with cultured swine granulosa cells. Biochem J. 1986 Nov 1; 239(3):505-11.
    View in: PubMed
  229. Manni A, Wright C, Demers L, Luk G. Polyamines and hormonal regulation of N-nitrosomethylurea-induced rat mammary tumor growth in vivo. Cancer Res. 1986 Oct; 46(10):4938-41.
    View in: PubMed
  230. Buchanan JR, Santen R, Cauffman S, Cavaliere A, Greer RB, Demers LM. The effect of endogenous estrogen fluctuation on metabolism of 25-hydroxyvitamin D. Calcif Tissue Int. 1986 Sep; 39(3):139-44.
    View in: PubMed
  231. Buchanan JR, Santen RJ, Cavaliere A, Cauffman SW, Greer RB, Demers LM. Interaction between parathyroid hormone and endogenous estrogen in normal women. Metabolism. 1986 Jun; 35(6):489-94.
    View in: PubMed
  232. Manni A, Wright C, Feil P, Baranao L, Demers L, Garcia M, Rochefort H. Autocrine stimulation by estradiol-regulated growth factors of rat hormone-responsive mammary cancer: interaction with the polyamine pathway. Cancer Res. 1986 Apr; 46(4 Pt 1):1594-8.
    View in: PubMed
  233. Veldhuis JD, Evans WS, Demers LM, Thorner MO, Wakat D, Rogol AD. Altered neuroendocrine regulation of gonadotropin secretion in women distance runners. J Clin Endocrinol Metab. 1985 Sep; 61(3):557-63.
    View in: PubMed
  234. Hahn DW, McGuire JL, Carraher RP, Demers LM. Influence of ovarian steroids on prostaglandin- and leukotriene-induced uterine contractions. Am J Obstet Gynecol. 1985 Sep 1; 153(1):87-91.
    View in: PubMed
  235. Veldhuis JD, Demers LM. A role for somatomedin C as a differentiating hormone and amplifier of hormone action on ovarian cells: studies with synthetically pure human somatomedin C and swine granulosa cells. Biochem Biophys Res Commun. 1985 Jul 16; 130(1):234-40.
    View in: PubMed
  236. Lookingbill DP, Horton R, Demers LM, Egan N, Marks JG, Santen RJ. Tissue production of androgens in women with acne. J Am Acad Dermatol. 1985 Mar; 12(3):481-7.
    View in: PubMed
  237. Kulin HE, Samojlik E, Demers LM, Santner SJ. Response of the prepubertal ovary to acute chorionic gonadotropin administration: absence of modulation by growth hormone. J Clin Endocrinol Metab. 1985 Jan; 60(1):208-11.
    View in: PubMed
  238. Demers LM. Prostaglandins in human disease. Clin Lab Med. 1984 Dec; 4(4):787-801.
    View in: PubMed
  239. Veldhuis JD, Gwynne JT, Strauss JF, Demers LM. Role of estradiol as a biological amplifier of gonadotropin action in the ovary: in vitro studies using swine granulosa cells and homologous lipoproteins. Endocrinology. 1984 Jun; 114(6):2312-22.
    View in: PubMed
  240. Rees MC, Anderson AB, Demers LM, Turnbull AC. Endometrial and myometrial prostaglandin release during the menstrual cycle in relation to menstrual blood loss. J Clin Endocrinol Metab. 1984 May; 58(5):813-8.
    View in: PubMed
  241. Santen RJ, Demers LM, Max DT, Smith J, Stein BS, Glode LM. Long term effects of administration of a gonadotropin-releasing hormone superagonist analog in men with prostatic carcinoma. J Clin Endocrinol Metab. 1984 Feb; 58(2):397-400.
    View in: PubMed
  242. Veldhuis JD, Klase PA, Demers LM, Chafouleas JG. Mechanisms subserving calcium's modulation of luteinizing hormone action in isolated swine granulosa cells. Endocrinology. 1984 Feb; 114(2):441-9.
    View in: PubMed
  243. Demers LM, Brennecke SP, Mountford LA, Brunt JD, Turnbull AC. Development and validation of a radioimmunoassay for prostaglandin E2 metabolite levels in plasma. J Clin Endocrinol Metab. 1983 Jul; 57(1):101-6.
    View in: PubMed
  244. Warner B, Worgul TJ, Drago J, Demers L, Dufau M, Max D, Santen RJ. Effect of very high dose D-leucine6-gonadotropin-releasing hormone proethylamide on the hypothalamic-pituitary testicular axis in patients with prostatic cancer. J Clin Invest. 1983 Jun; 71(6):1842-53.
    View in: PubMed
  245. Demers LM, Dourte B, Hutchinson B. Urine urea nitrogen as measured in the Beckman Astra-8. Clin Chem. 1983 Jun; 29(6):1310-1.
    View in: PubMed
  246. Reeves WC, Demers LM, Wood MA, Skarlatos S, Copenhaver G, Whitesell L, Luderer JR. The release of thromboxane A2 and prostacyclin following experimental acute pulmonary embolism. Prostaglandins Leukot Med. 1983 May; 11(1):1-10.
    View in: PubMed
  247. López Bernal A, Anderson AB, Demers LM, Turnbull AC. Glucocorticoid binding by human fetal membranes at term. J Clin Endocrinol Metab. 1982 Nov; 55(5):862-5.
    View in: PubMed
  248. Brenner DE, Harvey HA, Lipton A, Demers L. A study of prostaglandin E2, parathormone, and response to indomethacin in patients with hypercalcemia of malignancy. Cancer. 1982 Feb 1; 49(3):556-61.
    View in: PubMed
  249. Stumpf PG, Maruca J, Santen RJ, Demers LM. Development of a vaginal ring for achieving physiologic levels of 17 beta-estradiol in hypoestrogenic women. J Clin Endocrinol Metab. 1982 Jan; 54(1):208-10.
    View in: PubMed
  250. Santner SJ, Santen RJ, Kulin HE, Demers LM. A model for validation of radioimmunoassay kit reagents: measurement of follitropin and lutropin in blood and urine. Clin Chem. 1981 Nov; 27(11):1892-5.
    View in: PubMed
  251. Demers LM, Harrison TS, Halbert DR, Santen RJ. Effect of prolonged exercise on plasma prostaglandin levels. Prostaglandins Med. 1981 Apr; 6(4):413-8.
    View in: PubMed
  252. Quinones GR, Rohner TJ, Drago JR, Demers LM. Will prostatic acid phosphatase determination by radioimmunoassay increase the diagnosis of early prostatic cancer? J Urol. 1981 Mar; 125(3):361-4.
    View in: PubMed
  253. Santen RJ, Samojlik E, Demers L, Badder E. Adrenal of male dog secretes androgens and estrogens. Am J Physiol. 1980 Aug; 239(2):E109-12.
    View in: PubMed
  254. Naeye RL, Fisher R, Rubin HR, Demers LM. Selected hormone levels in victims of the sudden infant death syndrome. Pediatrics. 1980 Jun; 65(6):1134-6.
    View in: PubMed
  255. Hahn DW, Demers LM, McGuire JL. Studies on the mechanism of the antifertility activity of human chorionic gonadotropin in rodents. Contraception. 1980 May; 21(5):551-60.
    View in: PubMed
  256. Demers LM, Jones DE. Serum concentration of bile acids in maternal blood and cord blood at parturition. Am J Obstet Gynecol. 1980 May 1; 137(1):146-7.
    View in: PubMed
  257. Marcus JI, Demers LM. Probable deficiencies in the DuPont aca method for CK-MB. Clin Chem. 1980 May; 26(6):789.
    View in: PubMed
  258. Veldhuis JD, Demers LM, Hammond JM. Regulation of ornithine decarboxylase in isolated granulosa cells in vitro by constituents of follicular fluid. Endocrinology. 1979 Nov; 105(5):1143-51.
    View in: PubMed
  259. Abt AB, Demers LM, Shochat SJ. Cystic nephroma: an ultrastructural and biochemical study. J Urol. 1979 Oct; 122(4):539-41.
    View in: PubMed
  260. Demers LM, Ebright L, Derck DD. Improved radioimmunoassay for 11-deoxycortisol (compound S) in plasma. Clin Chem. 1979 Oct; 25(10):1704-7.
    View in: PubMed
  261. Veldhuis JD, Kulin HE, Demers LM, Lambert PW. Infantile hypercalcemia with subcutaneous fat necrosis: endocrine studies. J Pediatr. 1979 Sep; 95(3):460-2.
    View in: PubMed
  262. Demers LM. Free thyroxine assay and thyroxine index compared. Clin Chem. 1979 Jul; 25(7):1349-50.
    View in: PubMed
  263. Osterman J, Demers LM, Hammond JM. Indomethacin blocks gonadotropin stimulation of ovarian ornithine decarboxylase activity by inhibiting protein synthesis. Prostaglandins. 1979 Feb; 17(2):269-76.
    View in: PubMed
  264. Osterman J, Demers LM, Hammond JM. Gonadotropin stimulation of porcine ovarian ornithine decarboxylase in vitro: the role of 3',5'-adenosine monophosphate. Endocrinology. 1978 Nov; 103(5):1718-24.
    View in: PubMed
  265. Jones DE, Miranda R, Wolfe M, Demers LM. Serum concentration of bile acids in relation to the normal menstrual cycle the administration or oral contraceptives, and pregnancy. Am J Obstet Gynecol. 1978 Mar 1; 130(5):593.
    View in: PubMed
  266. Santen RJ, Wells SA, Cohn N, Demers LM, Misbin RI, Foltz EL. Compensatory increase in TSH secretion without effect on prolactin secretion in patients treated with aminoglutethimide. J Clin Endocrinol Metab. 1977 Oct; 45(4):739-46.
    View in: PubMed
  267. Harvey HA, Allegra JC, Demers LM, Luderer JR, Brenner DE, Trautlein JJ, White DS, Gillin MA, Lipton A. Immunosuppression and human cancer: role of prostaglandins. Cancer. 1977 Jun; 39(6):2362-4.
    View in: PubMed
  268. Mortel R, Allegra JC, Demers LM, Harvey HA, Trautlein J, Nahhas W, White D, Gillin MA, Lipton A. Plasma prostaglandins across the tumor bed of patients with gynecologic malignancy. Cancer. 1977 May; 39(5):2201-3.
    View in: PubMed
  269. Demers LM, Allegra JC, Harvey HA, Lipton A, Luderer JR, Mortel R, Brenner DE. Plasma prostaglandins in hypercalcemic patients with neoplastic disease. Cancer. 1977 Apr; 39(4):1559-62.
    View in: PubMed
  270. Demers LM, Feil PD, Bardin CW. Factors that influence steroid induction of endometrial glycogenesis in organ culture. Ann N Y Acad Sci. 1977 Mar 11; 286:249-59.
    View in: PubMed
  271. Feil PD, Pegg AE, Demers LM, Bardin CW. Involvement of polyamines in the progestin-induced stimulation of endometrial glycogen synthesis during organ culture. Biochem Biophys Res Commun. 1977 Mar 7; 75(1):1-6.
    View in: PubMed
  272. Demers LM, Gabbe SG. Placental prostaglandin levels in pre-eclampsia. Am J Obstet Gynecol. 1976 Sep 1; 126(1):137-9.
    View in: PubMed
  273. Allegra J, Lipton A, Harvey H, Luderer J, Brenner D, Mortel R, Demers L, Gillin M, White D, Trautlein J. Decreased prevalence of immediate hypersensitivity (atopy) in a cancer population. Cancer Res. 1976 Sep; 36(9 pt.1):3225-6.
    View in: PubMed
  274. Demers LM, Hepner G. Radioimmunoassay of bile acids in serum. Clin Chem. 1976 May; 22(5):602-6.
    View in: PubMed
  275. Sampson EJ, Derck DD, Demers LM. Comparison of results for 13 clinical laboratory determinations with three automated analytical systems. Clin Chem. 1976 Mar; 22(3):346-9.
    View in: PubMed
  276. Sampson EJ, Demers LM, Krieg AF. Faster enzymatic procedure for serum triglycerides. Clin Chem. 1975 Dec; 21(13):1983-5.
    View in: PubMed
  277. Makino T, Demers LM, Greep RO. Factors influencing pituitary glycogen metabolism and gonadotropic hormone release. I. Luteinizing hormone-releasing hormone. Fertil Steril. 1974 Oct; 25(10):872-7.
    View in: PubMed
  278. Demers LM, Makino T, Greep RO. Factors influencing pituitary glycogen metabolism and gonadotropic hormone release. II. A role of prostaglandins. Fertil Steril. 1974 Oct; 25(10):878-84.
    View in: PubMed
  279. Demers LM, Yoshinaga K, Greep RO. Prostaglandin F in moneky uterine fluid during the menstrual cycle and following steroid treatment. Prostaglandins. 1974 Mar 25; 5(6):513-9.
    View in: PubMed
  280. Schlegel W, Demers LM, Hildebrandt-Stark HE, Behrman HR, Greep RO. Partial purification of human placental 15-hydroxy-prostaglandin dehydrogenase: kinetic properties. Prostaglandins. 1974 Mar 10; 5(5):417-33.
    View in: PubMed
  281. Demers LM, Jacobs RD. Hormonal regulation of rat uterine glycogen metabolism. Biol Reprod. 1973 Oct; 9(3):272-8.
    View in: PubMed
  282. Demers LM, Jacobs RD, Greep RO. Comparative effects of ovarian steroids on glycogen metabolism of rat, rabbit and guinea pig uterine tissue. Proc Soc Exp Biol Med. 1973 Sep; 143(4):1158-63.
    View in: PubMed
  283. Macdonald GJ, Demers LM, Greep RO. Peripheral serum progesterone and correlated endometrial glycogen levels during the menstrual cycle of Macaca arctoides. Fertil Steril. 1973 Feb; 24(2):98-103.
    View in: PubMed
  284. Demers LM, Behrman HR, Greep RO. Effects of prostaglandins and gonadotrophins on luteal prostaglandin and steroid biosynthesis. Adv Biosci. 1973; 9:701-7.
    View in: PubMed
  285. Gebbe SG, Demers LM, Greep RO, Villee CA. The effects of hypoxia on placental glycogen metabolism. Am J Obstet Gynecol. 1972 Oct 15; 114(4):540-5.
    View in: PubMed
  286. Demers LM, Macdonald GJ, Hertig AT, King NW, Mackey JJ. The cervix uteri in Macaca mulatta, Macaca arctoides, and Macaca fascicularis--a comparative anatomic study with special reference to Macaca arctoides as a unique model for endometrial study. Fertil Steril. 1972 Aug; 23(8):529-34.
    View in: PubMed
  287. Demers LM. The morning-after pill. N Engl J Med. 1971 May 6; 284(18):1034-6.
    View in: PubMed
  288. Csermely T, Hughes EC, Demers LM. Effect of oral contraceptives on human endometrium in culture. Am J Obstet Gynecol. 1971 Apr 1; 109(7):1066-72.
    View in: PubMed
  289. Verdy M, Beaulieu R, Demers L. Plasma calcitonin activity in a patient with thyroid medullary carcinoma and her children with osteopetrosis. J Clin Endocrinol Metab. 1971 Feb; 32(2):216-21.
    View in: PubMed
  290. Hughes EC, Demers LM, Csermely T, Jones DB. Organ culture of human endometrium. Effect of ovarian steroids. Am J Obstet Gynecol. 1969 Nov 1; 105(5):707-20.
    View in: PubMed
Demers's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts
_
Co-Authors
_
Similar People
_
Same Department
Physical Neighbors
_