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Akif Undar

TitleProfessor
InstitutionCollege of Medicine
DepartmentPediatrics
Address500 University Drive Hershey PA 17033
Mailbox: H085
Phone7175316700

 Overview 
 overview
PREFERRED TITLE/ROLE:



Professor of Pediatrics, Surgery, and Bioengineering



SECONDARY APPOINTMENT(S)/ INSTITUTE(S)/ CENTER(S):



Surgery and Bioengineering



GRADUATE PROGRAM AFFILIATIONS:



Bioengineering, MD/PhD Degree Program



EDUCATION:



B.S., Yildiz University, 1986

M.S., Southwest Texas State University, 1992

M.S.E., University of Texas at Austin, 1994

Ph.D., University of Texas at Austin, 1996



NARRATIVE:



After completing his undergraduate degree in Electrical Engineering and his first master's degree in Computer Science, Dr. Ündar decided to pursue a career in Biomedical Engineering because it combines engineering with medicine. His aspiration for biomedical engineering was and still is to help underserved populations. Therefore, he intentionally stayed in academia in an effort to improve the lives of underserved individuals regardless of the commercial profit.



His passion is the development of novel technologies and methodologies to be used in minimizing the adverse effects of cardiovascular operations, mechanical circulatory support systems and cardiopulmonary bypass procedures in neonates, infants, and children. In particular, Dr. Ündar focuses on research in minimizing cerebral, myocardial, pulmonary, and renal injury during and after pediatric cardiopulmonary bypass procedures and mechanical circulatory support. His research specialties include pediatric heart-lung machines, pulsatile versus non-pulsatile perfusion, pediatric mechanical circulatory support systems, complement, neutrophil, platelet, and cytokine inhibition during pediatric open-heart procedures, microdevices for measuring systemic inflammation in real-time, detection and classification of microemboli, blood viscoelasticity, and plasma proteomics.



He is the Founder & Director of the Penn State Hershey Pediatric Cardiovascular Research Center. http://www.pennstatehershey.org/web/pedscardiacresearch/home



He is also the Founder & President of an International Society for Pediatric Mechanical Cardiopulmonary Support (Non-profit tax exempt [503 (c) (3)] scientific organization).

http://www.cvent.com/EVENTS/Info/Summary.aspx?e=3b84e6a4-9dac-4c76-963c-0bd7045dff56



Dr. Ündar has also established an International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion. http://www.hmc.psu.edu/childrens/pedscpb/



The first annual meeting was held at the Hotel Hershey, Hershey, Pennsylvania in May of 2005. Since then, we have had eight international conferences with over 2,055 participants from 33 countries in attendance at these events. Based on full manuscripts, 65 Young Investigator Awards were awarded during the past eight years. As a result of these events, over 395 manuscripts have been generated for this underserved research area. These publications have become the largest resource for the investigators of pediatric mechanical cardiovascular research.



These three major entities, International Conference, Research Center, and International Society have an identical mission and three major objectives. The mission is to focus on the current problems associated with pediatric cardiac patients during and after acute or chronic cardiac support. The International Conference, Research Center, and International Society will bring together as many distinguished clinicians, bioengineers, and basic scientists as possible to precisely define current problems and suggest novel approaches and solutions.



Major objectives are to:

1. Establish International Conference, Research Center, and International Society as the leading forum for further development of novel treatments and devices for cardiovascular health in pediatric populations at the pediatric heart centers around the world.

2. Provide high-quality rigorous education for bioengineers, medical students, residents, post-doctoral fellows and junior faculty members in pediatric cardiovascular research.

3. Maintain pediatric international conference International Conference for Pediatric Mechanical Circulatory Support Systems & Pediatric Cardiopulmonary Perfusion as the leading conference for defining the problems and needs of current mechanical circulatory support systems in pediatric patients and suggesting appropriate solutions for underserved pediatric cardiac patients around the globe.



Dr. Ündar have authored and co-authored over 550 publications (over 225 articles, 11 conference proceedings and over 300 abstracts), including several invited editorials (as of September 2012). To date, Dr. Ündar have presented over 360 scientific papers including several invited lectures and visiting professorships at national and international conferences. He has also organized several scientific panels for national and international conferences.








 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Agirbasli MA, Song J, Lei F, Wang S, Kunselman AR, Clark JB, Myers JL, Ündar A. . Comparative effects of pulsatile and non-pulsatile flow on plasma fibrinolytic balance in pediatric patients undergoing cardiopulmonary bypass. Artificial Organs. 2014; 38(1): (in press).
  2. Durandy Y, Wang S, Ündar A. . An original versatile non-occlusive pressure regulated blood roller pump for extracorporeal perfusion. Artifical Organs. 2014.
  3. Wang S, Kunselman AR, Ündar A. . In vitro performance analysis of novel pulsatile diagonal pump in simulated pediatric mechanical circulatory support system. Artificial Organs (in press). . 2014.
  4. Palanzo DA, Baer LD, El-Banayosy A, Wang S, Undar A, Pae WE. Choosing a pump for extracorporeal membrane oxygenation in the USA. Artif Organs. 2014 Jan; 38(1):1-4.
    View in: PubMed
  5. Undar A, Wang S, Palanzo D, Weaver B, Pekkan K, Agirbasli M, Zahn JD, Luciani GB, Clark JB, Wilson RP, Kunselman AR, Sano S, Belli E, Pierce WS, Myers JL. Outcomes of the ninth international conference on pediatric mechanical circulatory support systems and pediatric cardiopulmonary perfusion. Artif Organs. 2014 Jan; 38(1):5-10.
    View in: PubMed
  6. Evenson A, Wang S, Kunselman AR, Undar A. Use of a novel diagonal pump in an in vitro neonatal pulsatile extracorporeal life support circuit. Artif Organs. 2014 Jan; 38(1):E1-9.
    View in: PubMed
  7. Undar A, Wang S, Palanzo DA. Impact of polymethylpentene oxygenators on outcomes of all extracorporeal life support patients in the United States. Artif Organs. 2013 Dec; 37(12):1080-1.
    View in: PubMed
  8. Wang S, Kunselman AR, Undar A. In vitro performance analysis of a novel pulsatile diagonal pump in a simulated pediatric mechanical circulatory support system. Artif Organs. 2014 Jan; 38(1):64-72.
    View in: PubMed
  9. Agirbasli MA, Song J, Lei F, Wang S, Kunselman AR, Clark JB, Myers JL, Undar A. Comparative effects of pulsatile and nonpulsatile flow on plasma fibrinolytic balance in pediatric patients undergoing cardiopulmonary bypass. Artif Organs. 2014 Jan; 38(1):28-33.
    View in: PubMed
  10. Haydin S, Undar A. [Updates on extracorporeal life support in the world and challenges in Turkey]. Anadolu Kardiyol Derg. 2013 Sep; 13(6):580-8.
    View in: PubMed
  11. Dhami R, Wang S, Kunselman AR, Undar A. In vitro comparison of the delivery of gaseous microemboli and hemodynamic energy for a diagonal and a roller pump during simulated infantile cardiopulmonary bypass procedures. Artif Organs. 2014 Jan; 38(1):56-63.
    View in: PubMed
  12. Krawiec C, Wang S, Kunselman AR, Undar A. Impact of Pulsatile Flow on Hemodynamic Energy in a Medos Deltastream DP3 Pediatric Extracorporeal Life Support System. Artif Organs. 2014 Jan; 38(1):19-27.
    View in: PubMed
  13. Menon PG, Antaki JF, Undar A, Pekkan K. Aortic outflow cannula tip design and orientation impacts cerebral perfusion during pediatric cardiopulmonary bypass procedures. Ann Biomed Eng. 2013 Dec; 41(12):2588-602.
    View in: PubMed
  14. Markmann T, Undar A. Outcomes of the International Pediatric Perfusion Symposiums. Artif Organs. 2013 Feb; 37(2):116-20.
    View in: PubMed
  15. Strother A, Wang S, Kunselman AR, Ündar A. Handling ability of gaseous microemboli of two pediatric arterial filters in a simulated CPB model. Perfusion. 2013 May; 28(3):244-52.
    View in: PubMed
  16. Albal PG, Menon PG, Kowalski W, Undar A, Turkoz R, Pekkan K. Novel fenestration designs for controlled venous flow shunting in failing Fontans with systemic venous hypertension. Artif Organs. 2013 Jan; 37(1):66-75.
    View in: PubMed
  17. Ündar A. . [Editor]. The Proceedings of the Ninth International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion. 2013; 9(9):(in press).
  18. Wang S, Kunselman AR, Ündar A. Novel pulsatile diagonal pump for pediatric extracorporeal life support system. Artif Organs. 2013 Jan; 37(1):37-47.
    View in: PubMed
  19. Sasso LA, Aran K, Guan Y, Ündar A, Zahn JD. Continuous monitoring of inflammation biomarkers during simulated cardiopulmonary bypass using a microfluidic immunoassay device - a pilot study. Artif Organs. 2013 Jan; 37(1):E9-E17.
    View in: PubMed
  20. Agirbasli M, Ündar A. Monitoring biomarkers after pediatric heart surgery: a new paradigm on the horizon. Artif Organs. 2013 Jan; 37(1):10-5.
    View in: PubMed
  21. Ündar A. . 2013 (4) (in press). Welcome to the 9th International Conference on Pediatric Mechanical Circulatory Support Systems & Pediatric Cardiopulmonary Perfusion. Artificial Organs. 2013; 4(37):(in press).
  22. Undar A, Wang S. Current devices for pediatric extracorporeal life support and mechanical circulatory support systems in the United States. Biomed Mater Eng. 2013; 23(1-2):57-62.
    View in: PubMed
  23. Ündar A. . The Proceedings of the Penn State Hershey Pediatric Cardiovascular Research Center: 2013 Update [Editor]. 2013; 3(3):(in press).
  24. Wang S, Durandy Y, Kunselman AR, Ündar A. A nonocclusive, inexpensive pediatric pulsatile roller pump for cardiopulmonary bypass, extracorporeal life support, and left/right ventricular assist systems. Artif Organs. 2013 Jan; 37(1):48-56.
    View in: PubMed
  25. Ündar A, Akçevin A, Alkan-Bozkaya T, Bakir I, Pauliks L, Palanzo D, Durandy Y, Ersayin-Kantas H, Ravishankar C, Gruenwald CE, Sandica E, Sun K, Türköz R, Pekkan K, Ceyran H, Weaver B, Pierce WS, Myers JL. Outcomes of the Eighth International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion. Artif Organs. 2013 Jan; 37(1):1-9.
    View in: PubMed
  26. Menon PG, Teslovich N, Chen CY, Undar A, Pekkan K. Characterization of neonatal aortic cannula jet flow regimes for improved cardiopulmonary bypass. J Biomech. 2013 Jan 18; 46(2):362-72.
    View in: PubMed
  27. Alkan-Bozkaya T, Akçevin A, Türkoglu H, Ündar A. Impact of pulsatile perfusion on clinical outcomes of neonates and infants with complex pathologies undergoing cardiopulmonary bypass procedures. Artif Organs. 2013 Jan; 37(1):82-6.
    View in: PubMed
  28. Undar A, Wang S, Krawiec C. Impact of a unique international conference on pediatric mechanical circulatory support and pediatric cardiopulmonary perfusion research. Artif Organs. 2012 Nov; 36(11):943-50.
    View in: PubMed
  29. Undar A, Wang S. Translational research is a necessity for selecting the best components of the extracorporeal circuitry for neonatal and pediatric CPB patients. Perfusion. 2013 Mar; 28(2):171-2.
    View in: PubMed
  30. Mathis RK, Lin J, Dogal NM, Qiu F, Kunselman A, Wang S, Ündar A. Evaluation of four pediatric cardiopulmonary bypass circuits in terms of perfusion quality and capturing gaseous microemboli. Perfusion. 2012 Nov; 27(6):470-9.
    View in: PubMed
  31. Ündar A, Palanzo D, Wang S. Using a secondary reservoir for pump suckers to avoid the generation of foam during CPB procedures in pediatric patients. Perfusion. 2012 Nov; 27(6):556-8.
    View in: PubMed
  32. Wang S, Palanzo D, Ündar A. Current ultrafiltration techniques before, during and after pediatric cardiopulmonary bypass procedures. Perfusion. 2012 Sep; 27(5):438-46.
    View in: PubMed
  33. Ündar A, Akçevin A, Pauliks LB, Palanzo D, Durandy Y, Myers JL. Welcome to the 8th International Conference on Pediatric Mechanical Circulatory Support Systems & Pediatric Cardiopulmonary Perfusion. Artif Organs. 2012 May; 36(5):460-2.
    View in: PubMed
  34. Ündar A. Facts and myths surrounding pediatric mechanical cardiovascular circulatory support research: a personal perspective. Artif Organs. 2012 May; 36(5):467-9.
    View in: PubMed
  35. Ündar A, Alkan-Bozkaya T, Palanzo D, Ersayin-Kantas H, Chin C, Ödemis E, Pekkan K, Agirbasli MA, Türköz A, Türköz R, Haydin S, Erek E, Yalçinbas YK, Sasmazel A, Karaci AR, Erkan H, Çicek AE, Bakir Í, Sarioglu T, Akçevin A, Aytaç A. Istanbul symposium on neonatal and pediatric cardiopulmonary bypass procedures. Artif Organs. 2012 May; 36(5):463-6.
    View in: PubMed
  36. Onan IS, Yivli P, Erkan H, Akçevin A, Ündar A, Bakir I. Perfusion practices and education of perfusionists for open heart surgery in Turkey--current practices and future suggestions. Artif Organs. 2012 May; 36(5):492-5.
    View in: PubMed
  37. Lin J, Dogal NM, Mathis RK, Qiu F, Kunselman A, Ündar A. Evaluation of Quadrox-i and Capiox FX neonatal oxygenators with integrated arterial filters in eliminating gaseous microemboli and retaining hemodynamic properties during simulated cardiopulmonary bypass. Perfusion. 2012 May; 27(3):235-43.
    View in: PubMed
  38. Reed-Thurston D, Qiu F, Ündar A, Kopenhaver-Haidet K, Shenberger J. . Pediatric and neonatal extracorporeal life support technology component utilization: Are U.S. clinicians implementing new technology?. Artificial Organs. 2012; (in press).
  39. Jacobs ML, Undar A. "The respect of his colleagues ...". World J Pediatr Congenit Heart Surg. 2012 Jan 1; 3(1):7.
    View in: PubMed
  40. Clark JB, Barnes ML, Undar A, Myers JL. Multimodality neuromonitoring for pediatric cardiac surgery: our approach and a critical appraisal of the available evidence. World J Pediatr Congenit Heart Surg. 2012 Jan 1; 3(1):87-95.
    View in: PubMed
  41. Ündar A. . The Proceedings of the Penn State Hershey Pediatric Cardiovascular Research Center: 2011 Update. [Editor]. 2012; 2:1-266..
  42. Umstead TM, Lu CJ, Freeman WM, Myers JL, Clark JB, Thomas NJ, Icitovic N, Chinchilli VM, Undar A, Phelps DS. The kinetics of cardiopulmonary bypass: a dual-platform proteomics study of plasma biomarkers in pediatric patients undergoing cardiopulmonary bypass. Artif Organs. 2012 Jan; 36(1):E1-20.
    View in: PubMed
  43. Ündar A. . The Proceedings of the Seventh International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion. [Editor]. 2012; 8:1-139..
  44. Ündar A, Wang S, Krawiec C. . Impact of a unique international conference on pediatric mechanical circulatory support and pediatric cardiopulmonary perfusion research [invited editorial]. Artificial Organs. 2012; 11(36):(in press).
  45. Ündar A, Haydin S, Erek E, Ödemis E, Yivli P, Agirbasli MA, Alkan-Bozkaya T, Türköz A, Türköz R, Sasmazel A, Karaci AR, Çicek AE, Yalçinbas YK, Akçevin A, Tayyar Sarioglu T , Bakir I. . Turkish J Thoracic Cardiovascular Surgery. Recommendations For Techniques And Components’ Selection During Congenital Heart Surgery In Turkey. 2012; 20(2):399-405..
  46. Jacobs ML, Ündar A. “The Respect of His Colleagues…”[Editorial]. World Journal for Pediatric and Congenital Heart Surgery. 2012; 1(3):7.
  47. Sasso, L., I.H. Johnston, M. Zheng, R.K. Gupte, A. Ündar, and J.D. Zahn, . Automated MicrofluidicProcessing Platform for Multiplexed Magnetic Bead Immunoassays. Microfluidics and Nanofluidics. 2012; DOI 10.1007/s10404-012-0980-0.
  48. Clark JB, Barnes ML, Ündar A. Myers JL. Multimodality neuromonitoring for pediatric cardiac surgery: our approach and a critical appraisal of the available evidence [Invited Review]. World Journal for Pediatric and Congenital Heart Surgery. 2012; 1(3):87-95.
  49. Ündar A, Bakir I, Haydin S, Erek E, Yivli P, Ödemis E, Agirbasli MA., Alkan-Bozkaya T, Türköz A, Türköz R, Sasmazel A, Karaci AR, Çicek AE, Yalçinbas YK., Akçevin A, Sarioglu T. . Congenital heart surgery in Turkey: Today and Tomorrow (Editorial). Turkish J Thoracic Cardiovascular Surgery. 2012; 20(2):181-185..
  50. Dogal NM, Mathis RK, Lin J, Qiu F, Kunselman A, Undar A. Evaluation of three hollow-fiber membrane oxygenators without integrated arterial filters for neonatal cardiopulmonary bypass. Perfusion. 2012 Mar; 27(2):132-40.
    View in: PubMed
  51. Karaci AR, Sasmazel A, Aydemir NA, Saritas T, Harmandar B, Tuncel Z, Undar A. Comparison of parameters for detection of splanchnic hypoxia in children undergoing cardiopulmonary bypass with pulsatile versus nonpulsatile normothermia or hypothermia during congenital heart surgeries. Artif Organs. 2011 Nov; 35(11):1010-7.
    View in: PubMed
  52. Undar A, Ravishankar C, Gaynor JW, Baer LD, Clark JB, Wernowsky G, Myers JL. Outcomes of the Seventh International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion and Second Annual Meeting of the International Society for Pediatric Mechanical Cardiopulmonary Support. Artif Organs. 2011 Nov; 35(11):975-82.
    View in: PubMed
  53. Undar A, Haydin S, Yivli P, Weaver B, Pauliks L, Cicek AE, Erek E, Sasmazel A, Agirbasli MA, Alkan-Bozkaya T, Akçevin A, Bakir I. Istanbul Symposiums on Pediatric Extracorporeal Life Support Systems. Artif Organs. 2011 Nov; 35(11):983-8.
    View in: PubMed
  54. Pauliks LB, Undar A. Heart transplantation for congenital heart disease. World J Pediatr Congenit Heart Surg. 2011 Oct 1; 2(4):603-8.
    View in: PubMed
  55. Reed-Thurston D, Shenberger J, Qiu F, Undar A. Neonatal extracorporeal life support: will the newest technology reduce morbidity? Artif Organs. 2011 Nov; 35(11):989-96.
    View in: PubMed
  56. Qiu F, Lu CK, Palanzo D, Baer LD, Myers JL, Undar A. Hemodynamic evaluation of the Avalon Elite bi-caval dual lumen cannulae. Artif Organs. 2011 Nov; 35(11):1048-51.
    View in: PubMed
  57. Su XW, Guan Y, Barnes M, Clark JB, Myers JL, Undar A. Improved cerebral oxygen saturation and blood flow pulsatility with pulsatile perfusion during pediatric cardiopulmonary bypass. Pediatr Res. 2011 Aug; 70(2):181-5.
    View in: PubMed
  58. Qiu F, Talor J, Zahn J, Pauliks L, Kunselman AR, Palanzo D, Baer L, Woitas K, Wise R, McCoach R, Weaver B, Carney E, Haines N, Uluer MC, Aran K, Sasso LA, Alkan-Bozkaya T, Akcevin A, Guan Y, Wang S, Agirbasli M, Clark JB, Myers JL, Undar A. Translational research in pediatric extracorporeal life support systems and cardiopulmonary bypass procedures: 2011 update. World J Pediatr Congenit Heart Surg. 2011 Jul 1; 2(3):476-81.
    View in: PubMed
  59. Vasavada R, Khan S, Qiu F, Kunselman A, Undar A. Impact of oxygenator selection on hemodynamic energy indicators under pulsatile and nonpulsatile flow in a neonatal extracorporeal life support model. Artif Organs. 2011 Jun; 35(6):E101-7.
    View in: PubMed
  60. Qiu F, Clark JB, Kunselman AR, Undar A, Myers JL. Hemodynamic evaluation of arterial and venous cannulae performance in a simulated neonatal extracorporeal life support circuit. Perfusion. 2011 Jul; 26(4):276-83.
    View in: PubMed
  61. Clark JB, Pauliks LB, Myers JL, Undar A. Mechanical circulatory support for end-stage heart failure in repaired and palliated congenital heart disease. Curr Cardiol Rev. 2011 May; 7(2):102-9.
    View in: PubMed
  62. Undar A, Ravishankar C, Gaynor WJ, Baer LD, Clark JB, Wernowsky G, Myers JL. Welcome to the Seventh International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion. Artif Organs. 2011 Apr; 35(4):361-2.
    View in: PubMed
  63. Talor JJ, Undar A. Pediatric cardiopulmonary bypass: does perfusion mode matter? World J Pediatr Congenit Heart Surg. 2011 Apr; 2(2):296-300.
    View in: PubMed
  64. Undar A. Penn State Hershey Pediatric Cardiovascular Research Center: 2011 update. Artif Organs. 2011 Apr; 35(4):358-60.
    View in: PubMed
  65. Vasavada R. Current status of pediatric/neonatal extracorporeal life support: clinical outcomes, circuit evolution, and translational research. Perfusion. 2011 Jul; 26(4):294-301.
    View in: PubMed
  66. Clark JB, Guan Y, McCoach R, Kunselman AR, Myers JL, Undar A. An investigational study of minimum rotational pump speed to avoid retrograde flow in three centrifugal blood pumps in a pediatric extracorporeal life support model. Perfusion. 2011 May; 26(3):185-90.
    View in: PubMed
  67. Khan S, Vasavada R, Qiu F, Kunselman A, Undar A. Extracorporeal life support systems: alternative vs. conventional circuits. Perfusion. 2011 May; 26(3):191-8.
    View in: PubMed
  68. Pauliks LB and Ündar A. . Heart transplantation for congenital heart disease. World Journal for Pediatric and Congenital Heart Surgery. 2011; 2(4):603-608..
  69. Clark JB, Pauliks LB, Myers JL, Ündar A. Mechanical circulatory support for end-stage heart failure in repaired and palliated congenital heart disease. Current Cardiology Review. 2011; 7(2):102-109..
  70. Clark JB, Qiu F, Guan Y, Woitas KR, Myers JL, Undar A. Microemboli detection and classification during pediatric cardiopulmonary bypass. World J Pediatr Congenit Heart Surg. 2011 Jan; 2(1):111-4.
    View in: PubMed
  71. Ündar A. . Facts and myths surrounding pediatric mechanical cardiovascular circulatory support research: a personal perspective. The Proceedings of the Seventh International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion. 2011; 7:4-7..
  72. Talor J, Ündar A. . Pediatric cardiopulmonary bypass. Does perfusion mode Matter?. World Journal for Pediatric and Congenital Heart Surgery. 2011; 2(2):296-300..
  73. Clark JB, Qui F, Guan Y, Woitas KR, Myers JL, Ündar A. . Microemboli detection and classification during pediatric cardiopulmonary bypass. World Journal for Pediatric and Congenital Heart Surgery. 2011; 2(1):111-114..
  74. Ündar A. [Editor]. The Proceedings of the Seventh International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion. 2011; 7:1-121.
  75. Feng Qiu, MD, Jonathan Talor, BSE, Jeffrey Zahn, PhD, Linda Pauliks, MD, Allen R. Kunselman, MA, David Palanzo, CCP, Larry Baer, CCP, Karl Woitas, CCP, Robert Wise, CCP, Robert McCoach, RN, CCP, Bonnie Weaver, RN, MSN, CCRN, Elizabeth Carney, DVM, Yulong Guan, MD, Nikkole Haines, BS, Mehmet C. Uluer, ScM, Kiana Aran, BS Lawrance A. Sasso, BS Tijen Alkan-Bozkaya, MD, Atif Akcevin, MD, Yulong Guan, MD, Shigang Wang, MD, Mehmet Agirbasli, MD, J. Brian Clark, MD, John L. Myers, MD, Akif Ündar, PhD . Translational Research in Pediatric Extracorporeal Life Support Systems and Cardiopulmonary Bypass Procedures: 2011 Update. World Journal for Pediatric and Congenital Heart Surgery. 2011; 2(3):476-481..
  76. Su XW, Qiu F, Ündar A. Brain protection during pediatric cardiopulmonary bypass [Chinese]. Chinese Journal of Extracorporeal Circulation. 2011; 9(1):40-48..
  77. Ündar A. 2011; 1: 1-218. [Editor]. The Proceedings of the Penn State Hershey Pediatric Cardiovascular Research Center: 2011 Update. 2011; 1-218.
  78. An in vitro comparison of the ability of three commonly used pediatric cardiopulmonary bypass circuits to filter gaseous microemboli. Perfusion. 2011 Mar; 26(2):167-8.
    View in: PubMed
  79. Palanzo D, Guan Y, Wan C, Baer L, Kunselman A, Qiu F, Undar A. Air-handling capabilities of blood cardioplegia delivery systems in a simulated pediatric model. Artif Organs. 2010 Nov; 34(11):950-4.
    View in: PubMed
  80. Undar A. Outcomes of the Sixth International Conference on Pediatric Mechanical Circulatory Support systems and Pediatric Cardiopulmonary Perfusion and First Annual Meeting of the International Society for Pediatric Mechanical Cardiopulmonary Support. Artif Organs. 2010 Nov; 34(11):865-8.
    View in: PubMed
  81. Qiu F, Uluer MC, Kunselman A, Clark JB, Myers JL, Undar A. Impact of tubing length on hemodynamics in a simulated neonatal extracorporeal life support circuit. Artif Organs. 2010 Nov; 34(11):1003-9.
    View in: PubMed
  82. Alkan-Bozkaya T, Türkoglu H, Akçevin A, Paker T, Ozkan-Çerçi H, Dindar A, Ersoy C, Bayer V, Askin D, Undar A. Cardiac surgery of premature and low birthweight newborns: is a change of fate possible? Artif Organs. 2010 Nov; 34(11):891-7.
    View in: PubMed
  83. Agirbasli M, Nguyen ML, Win K, Kunselman AR, Clark JB, Myers JL, Undar A. Inflammatory and hemostatic response to cardiopulmonary bypass in pediatric population: feasibility of seriological testing of multiple biomarkers. Artif Organs. 2010 Nov; 34(11):987-95.
    View in: PubMed
  84. Akçevin A, Alkan-Bozkaya T, Qiu F, Undar A. Evaluation of perfusion modes on vital organ recovery and thyroid hormone homeostasis in pediatric patients undergoing cardiopulmonary bypass. Artif Organs. 2010 Nov; 34(11):879-84.
    View in: PubMed
  85. Qiu F, Guan Y, Su X, Kunselman A, Undar A. Evaluation of neonatal membrane oxygenators with respect to gaseous microemboli capture and transmembrane pressure gradients. Artif Organs. 2010 Nov; 34(11):923-9.
    View in: PubMed
  86. Palanzo D, Qiu F, Baer L, Clark JB, Myers JL, Undar A. Evolution of the extracorporeal life support circuitry. Artif Organs. 2010 Nov; 34(11):869-73.
    View in: PubMed
  87. Yee S, Qiu F, Su X, Rider A, Kunselman AR, Guan Y, Undar A. Evaluation of HL-20 roller pump and Rotaflow centrifugal pump on perfusion quality and gaseous microemboli delivery. Artif Organs. 2010 Nov; 34(11):937-43.
    View in: PubMed
  88. Umstead TM, Lu CJ, Freeman WM, Myers JL, Clark JB, Thomas NJ, Chinchilli VM, Vrana KE, Undar A, Phelps DS. Dual-platform proteomics study of plasma biomarkers in pediatric patients undergoing cardiopulmonary bypass. Pediatr Res. 2010 Jun; 67(6):641-9.
    View in: PubMed
  89. Guan Y, Su X, McCoach R, Wise R, Kunselman A, Undar A. Evaluation of Quadrox-i adult hollow fiber oxygenator with integrated arterial filter. J Extra Corpor Technol. 2010 Jun; 42(2):134-8.
    View in: PubMed
  90. Guan Y, Karkhanis T, Wang S, Rider A, Koenig SC, Slaughter MS, El Banayosy A, Undar A. Physiologic benefits of pulsatile perfusion during mechanical circulatory support for the treatment of acute and chronic heart failure in adults. Artif Organs. 2010 Jul; 34(7):529-36.
    View in: PubMed
  91. Su XW, Undar A. Brain protection during pediatric cardiopulmonary bypass. Artif Organs. 2010 Apr; 34(4):E91-102.
    View in: PubMed
  92. Undar A. Welcome letter: International Society for Pediatric Mechanical Cardiopulmonary Support. Artif Organs. 2010 Apr; 34(4):279.
    View in: PubMed
  93. Talor J, Yee S, Rider A, Kunselman AR, Guan Y, Undar A. Comparison of perfusion quality in hollow-fiber membrane oxygenators for neonatal extracorporeal life support. Artif Organs. 2010 Apr; 34(4):E110-6.
    View in: PubMed
  94. Undar A. Welcome letter: Sixth International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion. Artif Organs. 2010 Apr; 34(4):277-8.
    View in: PubMed
  95. Mechanical performance comparison between RotaFlow and CentriMag centrifugal blood pumps in an adult ECLS model. Perfusion. 2010 Mar; 25(2):71-6.
    View in: PubMed
  96. Ündar A. [Editor]. The Proceedings of the Sixth International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion. 2010; 6:1-131..
  97. Undar A, Pauliks L, Clark JB, Zahn J, Rosenberg G, Kunselman AR, Sun Q, Pekkan K, Saliba K, Carney E, Thomas N, Freeman W, Vrana K, El-Banayosy A, Ural SH, Wilson R, Umstead TM, Floros J, Phelps DS, Weiss W, Snyder A, Yang S, Kimatian S, Cyran SE, Chinchilli VM, Guan Y, Rider A, Haines N, Rogerson A, Alkan-Bozkaya T, Akcevin A, Sun K, Wang S, Cun L, Myers JL. Penn State Hershey--center for pediatric cardiovascular research. Artif Organs. 2009 Nov; 33(11):883-7.
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  98. Haines NM, Wang S, Kunselman A, Myers JL, Undar A. Comparison of pumps and oxygenators with pulsatile and nonpulsatile modes in an infant cardiopulmonary bypass model. Artif Organs. 2009 Nov; 33(11):993-1001.
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  99. Wang S, Woitas K, Clark JB, Myers JL, Undar A. Clinical real-time monitoring of gaseous microemboli in pediatric cardiopulmonary bypass. Artif Organs. 2009 Nov; 33(11):1026-30.
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  100. Undar A. Outcomes of the Fifth International Conference on Pediatric Mechanical Circulatory Support Systems & Pediatric Cardiopulmonary Perfusion. Artif Organs. 2009 Nov; 33(11):879-82.
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  101. Haines N, Wang S, Myers JL, Undar A. Comparison of two types of neonatal extracorporeal life support systems with pulsatile and nonpulsatile flow. Artif Organs. 2009 Nov; 33(11):958-66.
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  102. Guan Y, Palanzo D, Kunselman A, Undar A. Evaluation of membrane oxygenators and reservoirs in terms of capturing gaseous microemboli and pressure drops. Artif Organs. 2009 Nov; 33(11):1037-43.
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  103. Pauliks LB, Undar A, Clark JB, Myers JL. Segmental differences of impaired diastolic relaxation following cardiopulmonary bypass surgery in children: a tissue Doppler study. Artif Organs. 2009 Nov; 33(11):904-8.
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  104. Rogerson A, Guan Y, Kimatian SJ, Kunselman A, Clark JB, Myers JL, Undar A. Transcranial Doppler ultrasonography: a reliable method of monitoring pulsatile flow during cardiopulmonary bypass in infants and young children. J Thorac Cardiovasc Surg. 2010 Apr; 139(4):e80-2.
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  105. Wang S, Haines N, Richardson JS, Dasse KA, Undar A. Impact of the postpump resistance on pressure-flow waveform and hemodynamic energy level in a neonatal pulsatile centrifugal pump. ASAIO J. 2009 May-Jun; 55(3):277-81.
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  106. Wang S, Rider AR, Kunselman AR, Richardson JS, Dasse KA, Undar A. Effects of the pulsatile flow settings on pulsatile waveforms and hemodynamic energy in a PediVAS centrifugal pump. ASAIO J. 2009 May-Jun; 55(3):271-6.
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  107. Haines N, Wang S, Undar A, Alkan T, Akcevin A. Clinical outcomes of pulsatile and non-pulsatile mode of perfusion. J Extra Corpor Technol. 2009 Mar; 41(1):P26-9.
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  108. Miller A, Lu CK, Wang S, Umstead TM, Freeman WM, Vrana K, Yang S, Myers JL, Phelps DS, Zahn JD, Undar A. Pediatric cardiopulmonary bypass circuits: a review of studies conducted at the Penn State Pediatric Cardiac Research Laboratories. J Extra Corpor Technol. 2009 Mar; 41(1):P50-8.
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  109. Wang S, Haines N, Undar A. Quantification of pressure-flow waveforms and selection of components for the pulsatile extracorporeal circuit. J Extra Corpor Technol. 2009 Mar; 41(1):P20-5.
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  110. Wang S, Haines N, Undar A. Hemodynamic energy delivery of the pulsatile flow in a simulated pediatric extracorporeal circuit. ASAIO J. 2009 Jan-Feb; 55(1):96-9.
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  111. Zahn, J.D., S. Yang, A. Undar and P. Athanasiou (Vol. 2): , ISBN 978-1-904455-47-9. . Biomolecular Separation and Analysis. Herold, K.E. and Rasooly, A. (Eds.). Microscale Blood Separation Technology" In Lab on a Chip Technology (Vol. 2):. 2009; 2:pp. 69-107..
  112. Haines NM, Rycus PT, Zwischenberger JB, Bartlett RH, Undar A. Extracorporeal Life Support Registry Report 2008: neonatal and pediatric cardiac cases. ASAIO J. 2009 Jan-Feb; 55(1):111-6.
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  113. Rider AR, Ressler NM, Karkhanis TR, Kunselman AR, Wang S, Undar A. The impact of pump settings on the quality of pulsatility. ASAIO J. 2009 Jan-Feb; 55(1):100-5.
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  114. Ündar A. [Editor]. The Proceedings of the Fifth International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion. 2009; 5:1-131..
  115. Ressler N, Rider AR, Kunselman AR, Richardson JS, Dasse KA, Wang S, Undar A. A hemodynamic evaluation of the Levitronix Pedivas centrifugal pump and Jostra Hl-20 roller pump under pulsatile and nonpulsatile perfusion in an infant CPB model. ASAIO J. 2009 Jan-Feb; 55(1):106-10.
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  116. Pekkan K, Dur O, Sundareswaran K, Kanter K, Fogel M, Yoganathan A, Undar A. Neonatal aortic arch hemodynamics and perfusion during cardiopulmonary bypass. J Biomech Eng. 2008 Dec; 130(6):061012.
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  117. Wang S, Undar A. Vacuum-assisted venous drainage and gaseous microemboli in cardiopulmonary bypass. J Extra Corpor Technol. 2008 Dec; 40(4):249-56.
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  118. Miller A, Wang S, Myers JL, Undar A. Gaseous microemboli detection in a simulated pediatric CPB circuit using a novel ultrasound system. ASAIO J. 2008 Sep-Oct; 54(5):504-8.
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  119. Pauliks LB, Undar A, Clark JB, Myers JL. Intraoperative techniques to assess cardiac function-feasiblity of strain rate imaging in the perioperative period in children. ASAIO J. 2008 Sep-Oct; 54(5):454-7.
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  120. Win KN, Wang S, Undar A. Microemboli generation, detection and characterization during CPB procedures in neonates, infants, and small children. ASAIO J. 2008 Sep-Oct; 54(5):486-90.
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  121. Undar A, Ungerleider RM, Giacomuzzi C, Duncan BW, Rosenberg G, Pierce WS, Waldhausen JA, Myers JL. Fourth International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion. ASAIO J. 2008 Sep-Oct; 54(5):445-6.
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  122. Rider AR, Griffith K, Ressler N, Kunselman AR, Wang S, Undar A. A hemodynamic evaluation of the Medos Deltastream DP1 rotary pump and Jostra HL-20 roller pump under pulsatile and nonpulsatile perfusion in an infant cardiopulmonary bypass model--a pilot study. ASAIO J. 2008 Sep-Oct; 54(5):529-33.
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  123. Wang S, Win KN, Kunselman AR, Woitas K, Myers JL, Undar A. The capability of trapping gaseous microemboli of two pediatric arterial filters with pulsatile and nonpulsatile flow in a simulated infant CPB model. ASAIO J. 2008 Sep-Oct; 54(5):519-22.
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  124. Wang S, Kunselman AR, Myers JL, Undar A. Comparison of two different blood pumps on delivery of gaseous microemboli during pulsatile and nonpulsatile perfusion in a simulated infant CPB model. ASAIO J. 2008 Sep-Oct; 54(5):538-41.
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  125. Wang S, Baer L, Kunselman AR, Myers JL, Undar A. Delivery of gaseous microemboli with vacuum-assisted venous drainage during pulsatile and nonpulsatile perfusion in a simulated neonatal cardiopulmonary bypass model. ASAIO J. 2008 Jul-Aug; 54(4):416-22.
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  126. Wang S, Miller A, Myers JL, Undar A. "Stolen" blood flow: effect of an open arterial filter purge line in a simulated neonatal CPB model. ASAIO J. 2008 Jul-Aug; 54(4):432-5.
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  127. Lull ME, Carkaci-Salli N, Freeman WM, Myers JL, Midgley FM, Thomas NJ, Kimatian SJ, Vrana KE, Undar A. Plasma biomarkers in pediatric patients undergoing cardiopulmonary bypass. Pediatr Res. 2008 Jun; 63(6):638-44.
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  128. Schreiner RS, Rider AR, Myers JW, Ji B, Kunselman AR, Myers JL, Undar A. Microemboli detection and classification by innovative ultrasound technology during simulated neonatal cardiopulmonary bypass at different flow rates, perfusion modes, and perfusate temperatures. ASAIO J. 2008 May-Jun; 54(3):316-24.
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  129. Rider AR, Ji B, Kunselman AR, Weiss WJ, Myers JL, Undar A. A performance evaluation of eight geometrically different 10 Fr pediatric arterial cannulae under pulsatile and nonpulsatile perfusion conditions in an infant cardiopulmonary bypass model. ASAIO J. 2008 May-Jun; 54(3):306-15.
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  130. Pauliks LB, Undar A. New devices for pediatric mechanical circulatory support. Curr Opin Cardiol. 2008 Mar; 23(2):91-6.
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  131. Undar A. International conference on pediatric mechanical circulatory support systems and pediatric cardiopulmonary perfusion: outcomes and future directions. ASAIO J. 2008 Mar-Apr; 54(2):141-6.
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  132. Wang S, Haines N, Ündar A. . Quantification of pressure-flow waveforms and selection of components for the pulsatile ECC. The ANZCP Gazette – Official Publication of the Australian & New Zealand College of Perfusionists. 2008; 9(2):6-14.
  133. Ündar A. [Editor]. The Proceedings of the Fourth International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion. 2008; 4:1-132..
  134. Alkan T, Akçevin A, Undar A, Türkoglu H, Paker T, Aytaç A. Benefits of pulsatile perfusion on vital organ recovery during and after pediatric open heart surgery. ASAIO J. 2007 Nov-Dec; 53(6):651-4.
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  135. Rider AR, Schreiner RS, Undar A. Pulsatile perfusion during cardiopulmonary bypass procedures in neonates, infants, and small children. ASAIO J. 2007 Nov-Dec; 53(6):706-9.
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  136. Undar A, Ji B, Kunselman AR, Myers JL. Detection and classification of gaseous microemboli during pulsatile and nonpulsatile perfusion in a simulated neonatal CPB model. ASAIO J. 2007 Nov-Dec; 53(6):725-9.
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  137. Undar A, Ji B, Rider A, Lukic B, Kunselman AR, Weiss WJ, Myers JL. Comparison of four different pediatric 10F aortic cannulae during pulsatile versus nonpulsatile perfusion in a simulated neonatal model of cardiopulmonary bypass. ASAIO J. 2007 Nov-Dec; 53(6):778-84.
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  138. Lemaire SA, Ochoa LN, Conklin LD, Schmittling ZC, Undar A, Clubb FJ, Li Wang X, Coselli JS, Fraser CD. Nerve and conduction tissue injury caused by contact with BioGlue. J Surg Res. 2007 Dec; 143(2):286-93.
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  139. Lukic B, Zapanta CM, Khalapyan T, Connell J, Pae WE, Myers JL, Wilson RP, Undar A, Rosenberg G, Weiss WJ. The effect of left ventricular function and drive pressures on the filling and ejection of a pulsatile pediatric ventricular assist device in an acute animal model. ASAIO J. 2007 May-Jun; 53(3):379-84.
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  140. Ji B, Undar A. Precise quantification of pressure-flow waveforms during pulsatile and nonpulsatile perfusion. J Thorac Cardiovasc Surg. 2007 May; 133(5):1395; author reply 1396.
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  141. Yang S, Undar A, Zahn JD. Continuous cytometric bead processing within a microfluidic device for bead based sensing platforms. Lab Chip. 2007 May; 7(5):588-95.
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  142. Ji B, Undar A. Comparison of perfusion modes on microcirculation during acute and chronic cardiac support: is there a difference? Perfusion. 2007 Mar; 22(2):115-9.
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  143. Travis AR, Giridharan GA, Pantalos GM, Dowling RD, Prabhu SD, Slaughter MS, Sobieski M, Undar A, Farrar DJ, Koenig SC. Vascular pulsatility in patients with a pulsatile- or continuous-flow ventricular assist device. J Thorac Cardiovasc Surg. 2007 Feb; 133(2):517-24.
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  144. Ündar A, Alkan T, Akcevin A. . Pulsatility in pediatric perfusion. Proceedings of the 21st European Association for Cardio-Thoracic Surgery Annual Meeting. 2007; 21:92-94.
  145. Ündar A. [Editor]. The Proceedings of the Third International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion. 2007; 3:1-116..
  146. Yang S, Ji B, Undar A, Zahn JD. Microfluidic devices for continuous blood plasma separation and analysis during pediatric cardiopulmonary bypass procedures. ASAIO J. 2006 Nov-Dec; 52(6):698-704.
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  147. LeMaire SA, Ochoa LN, Conklin LD, Widman RA, Clubb FJ, Undar A, Schmittling ZC, Wang XL, Fraser CD, Coselli JS. Transcutaneous near-infrared spectroscopy for detection of regional spinal ischemia during intercostal artery ligation: preliminary experimental results. J Thorac Cardiovasc Surg. 2006 Nov; 132(5):1150-5.
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  148. Undar A, Ji B, Lukic B, Zapanta CM, Kunselman AR, Reibson JD, Weiss WJ, Rosenberg G, Myers JL. Quantification of perfusion modes in terms of surplus hemodynamic energy levels in a simulated pediatric CPB model. ASAIO J. 2006 Nov-Dec; 52(6):712-7.
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  149. Undar A, Ji B, Lukic B, Zapanta CM, Kunselman AR, Reibson JD, Khalapyan T, Baer L, Weiss WJ, Rosenberg G, Myers JL. Comparison of hollow-fiber membrane oxygenators with different perfusion modes during normothermic and hypothermic CPB in a simulated neonatal model. Perfusion. 2006 Nov; 21(6):381-90.
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  150. Agati S, Ciccarello G, Fachile N, Scappatura RM, Grasso D, Salvo D, Undar A, Mignosa C. DIDECMO: a new polymethylpentene oxygenator for pediatric extracorporeal membrane oxygenation. ASAIO J. 2006 Sep-Oct; 52(5):509-12.
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  151. Agati S, Ciccarello G, Salvo D, Turla G, Undar A, Mignosa C. Use of a novel anticoagulation strategy during ECMO in a pediatric population: single-center experience. ASAIO J. 2006 Sep-Oct; 52(5):513-6.
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  152. Alkan T, Akçevin A, Undar A, Türkoglu H, Paker T, Aytaç A. Effects of pulsatile and nonpulsatile perfusion on vital organ recovery in pediatric heart surgery: a pilot clinical study. ASAIO J. 2006 Sep-Oct; 52(5):530-5.
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  153. Agati S, Ciccarello G, Ocello S, Salvo D, Marcelletti C, Undar A, Mignosa C. Pulsatile ECMO and VAD: a dual use of a new device in pediatric cardiac patients. ASAIO J. 2006 Sep-Oct; 52(5):501-4.
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  154. Lull ME, Freeman WM, Myers JL, Midgley F, Kimatian SJ, Undar A, Vrana KE. Plasma proteomics: a noninvasive window on pathology and pediatric cardiac surgery. ASAIO J. 2006 Sep-Oct; 52(5):562-6.
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  155. Ji B, Undar A. An evaluation of the benefits of pulsatile versus nonpulsatile perfusion during cardiopulmonary bypass procedures in pediatric and adult cardiac patients. ASAIO J. 2006 Jul-Aug; 52(4):357-61.
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  156. Yang S, Undar A, Zahn JD. A microfluidic device for continuous, real time blood plasma separation. Lab Chip. 2006 Jul; 6(7):871-80.
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  157. Agati S, Mignosa C, Ciccarello G, Salvo D, Undar A. Initial European clinical experience with pulsatile extracorporeal membrane oxygenation. J Heart Lung Transplant. 2006 Apr; 25(4):400-3.
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  158. Undar A. Outcomes of the First International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion. ASAIO J. 2006 Jan-Feb; 52(1):1-3.
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  159. Yang S, Ündar A, Zahn JD. . Continuous particle cross over in microfluidic channels for continuous biosensing. Proceedings of ASME Conference, International Mechanical Engineering Conference Exp Fluids Engineering: IMECE. 2006; 16087:1-7.
  160. Ündar A. [Editor]. The Proceedings of the Second International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion. 2006; 2:1-130..
  161. Long JA, Undar A, Manning KB, Deutsch S. Viscoelasticity of pediatric blood and its implications for the testing of a pulsatile pediatric blood pump. ASAIO J. 2005 Sep-Oct; 51(5):563-6.
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  162. Undar A. Pulsatile versus nonpulsatile cardiopulmonary bypass procedures in neonates and infants: from bench to clinical practice. ASAIO J. 2005 Sep-Oct; 51(5):vi-x.
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  163. Agati S, Mignosa C, Ciccarello G, Dario S, Undar A. Pulsatile ECMO in neonates and infants: first European clinical experience with a new device. ASAIO J. 2005 Sep-Oct; 51(5):508-12.
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  164. Yang S, Undar A, Zahn JD. Blood plasma separation in microfluidic channels using flow rate control. ASAIO J. 2005 Sep-Oct; 51(5):585-90.
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  165. Undar A, Eichstaedt HC, Masai T, Bigley JE, Kunselman AR. Precise quantification of pulsatility is a necessity for direct comparisons of six different pediatric heart-lung machines in a neonatal CPB model. ASAIO J. 2005 Sep-Oct; 51(5):600-3.
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  166. Weiss WJ, Lukic B, Undar A. Energy equivalent pressure and total hemodynamic energy associated with the pressure-flow waveforms of a pediatric pulsatile ventricular assist device. ASAIO J. 2005 Sep-Oct; 51(5):614-7.
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  167. Undar A. Benefits of pulsatile flow during and after cardiopulmonary bypass procedures. Artif Organs. 2005 Sep; 29(9):688-90.
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  168. Undar A. Effect of hypothermic cardiopulmonary bypass on blood viscoelasticity in pediatric cardiac patients. ASAIO J. 2005 Sep-Oct; 51(5):522-4.
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  169. Undar A, Rosenberg G, Myers JL. Part 1: principles of research on pulsatile and nonpulsatile perfusion during chronic support. ASAIO J. 2005 May-Jun; 51(3):303-4; author reply 305-8.
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  170. Undar A, Rosenberg G, Myers JL. Major factors in the controversy of pulsatile versus nonpulsatile flow during acute and chronic cardiac support. ASAIO J. 2005 May-Jun; 51(3):173-5.
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  171. Undar A, Owens WR, McGarry MC, Surprise DL, Kilpack VD, Mueller MW, McKenzie ED, Fraser CD. Comparison of hollow-fiber membrane oxygenators in terms of pressure drop of the membranes during normothermic and hypothermic cardiopulmonary bypass in neonates. Perfusion. 2005 May; 20(3):135-8.
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  172. Undar A, Myers JL. Arterial pressure and pump flow rate during long-term pulsatile and nonpulsatile cardiac support. Ann Thorac Surg. 2005 Mar; 79(3):1093-4; author reply 1094.
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  173. Luo J, Undar A. Insights of neurologic dysfunction after coronary artery bypass grafting. Chest. 2005 Mar; 127(3):1075; author reply 1075-6.
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  174. Undar A, Zapanta CM, Reibson JD, Souba M, Lukic B, Weiss WJ, Snyder AJ, Kunselman AR, Pierce WS, Rosenberg G, Myers JL. Precise quantification of pressure flow waveforms of a pulsatile ventricular assist device. ASAIO J. 2005 Jan-Feb; 51(1):56-9.
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  175. Ündar A. [Editor]. The Proceedings of the First International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion. 2005; 1:1-114..
  176. Ündar A, Cicek A, Akcevin A, Sarioglu T. . Perfusion practices and education of perfusionists for open-heart surgery in Turkey. Turkish Journal of Thoracic and Cardiovascular Surgery. 2005; 13:123-126..
  177. Yang S, Ündar A, Zahn JD. . Proceedings of ASME Conference, International Mechanical Engineering Conference Exp Fluids Engineering:. Biological fluid separation in microfluidic channels using flow rate control. 2005; (80501):1-7.
  178. Undar A, Rosenberg G, Myers JL. Impact of pulsatile flow on microcirculation. ASAIO J. 2004 Nov-Dec; 50(6):624-5.
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  179. Undar A, Eichstaedt HC, Clubb FJ, Lu M, Bigley JE, Deady BA, Porter A, Vaughn WK, Fung M. Anesthetic induction with ketamine inhibits platelet activation before, during, and after cardiopulmonary bypass in baboons. Artif Organs. 2004 Oct; 28(10):959-62.
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  180. Undar A, McKenzie ED, McGarry MC, Owens WR, Surprise DL, Kilpack VD, Mueller MW, Stayer SA, Andropoulos DB, Towbin JA, Fraser CD. Outcomes of congenital heart surgery patients after extracorporeal life support at Texas Children's Hospital. Artif Organs. 2004 Oct; 28(10):963-6.
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  181. Undar A, Rosenberg G, Myers JL. How should investigators compare different perfusion modes or different types of pulsatile flow during chronic support? ASAIO J. 2004 Jul-Aug; 50(4):401-2.
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  182. Undar A. Controversy over the benefits of pulsatile perfusion. Int J Artif Organs. 2004 Jun; 27(6):509-10; author reply 511-2.
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  183. Undar A. Myths and truths of pulsatile and nonpulsatile perfusion during acute and chronic cardiac support. Artif Organs. 2004 May; 28(5):439-43.
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  184. Ündar A. . Principles and practices of pulsatile perfusion in pediatric and adult open-heart surgery. Turkish Journal of Thoracic and Cardiovascular Surgery. 2004; 12:215-219..
  185. Undar A. Energy equivalent pressure formula is for precise quantification of different perfusion modes. Ann Thorac Surg. 2003 Nov; 76(5):1777-8.
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  186. Undar A, LeMaire SA, Schmittling ZC, Coselli JS, Köksoy C, Deady BA, Fraser CD. Use of near-infrared spectroscopy to monitor regional cerebral oxygen saturation during infrarenal aortic crossclamping in piglets. Artif Organs. 2003 Sep; 27(9):849-53.
    View in: PubMed
  187. Undar A, Fraser CD. Quantification of arterial pressure and pump-flow waveforms for pulsatile- and continuous-flow devices during chronic support. J Heart Lung Transplant. 2003 Jun; 22(6):706; author reply 706-7.
    View in: PubMed
  188. Undar A. Universal and precise quantification of pulsatile and nonpulsatile pressure flow waveforms is necessary for direct and adequate comparisons among the results of different investigators. Perfusion. 2003 Apr; 18(2):135-6.
    View in: PubMed
  189. Undar A. Fundamentals of pulsatile versus nonpulsatile flow during chronic support. ASAIO J. 2003 Jan-Feb; 49(1):139-40.
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  190. Undar A. The ABCs of research on pulsatile versus nonpulsatile perfusion during cardiopulmonary bypass. Med Sci Monit. 2002 Dec; 8(12):ED21-4.
    View in: PubMed
  191. Undar A, Masai T, Beyer EA, Goddard-Finegold J, McGarry MC, Fraser CD. Pediatric physiologic pulsatile pump enhances cerebral and renal blood flow during and after cardiopulmonary bypass. Artif Organs. 2002 Nov; 26(11):919-23.
    View in: PubMed
  192. Undar A, Vaughn WK. Effects of mild hypothermic cardiopulmonary bypass on blood viscoelasticity in coronary artery bypass grafting patients. Artif Organs. 2002 Nov; 26(11):964-6.
    View in: PubMed
  193. Undar A, Fraser CD. The alphabet of research on pulsatile and nonpulsatile (continuous flow) perfusion during chronic support. Artif Organs. 2002 Sep; 26(9):812-3; author reply 813-5.
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  194. McMahon CJ, DiBardino DJ, Undar A, Fraser CD. Anomalous origin of left coronary artery from the right pulmonary artery in association with type III aortopulmonary window and interrupted aortic arch. Ann Thorac Surg. 2002 Sep; 74(3):919-21.
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  195. Undar A, Eichstaedt HC, Bigley JE, Deady BA, Porter AE, Vaughn WK, Fraser CD. Effects of pulsatile and nonpulsatile perfusion on cerebral hemodynamics investigated with a new pediatric pump. J Thorac Cardiovasc Surg. 2002 Aug; 124(2):413-6.
    View in: PubMed
  196. Undar A, Eichstaedt HC, Clubb FJ, Fung M, Lu M, Bigley JE, Vaughn WK, Fraser CD. Novel anti-factor D monoclonal antibody inhibits complement and leukocyte activation in a baboon model of cardiopulmonary bypass. Ann Thorac Surg. 2002 Aug; 74(2):355-62; discussion 362.
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  197. Undar A, Fraser CD. Anti-factor D monoclonal antibody, pulsatile flow and cardiotomy suction during cardiopulmonary bypass. Eur J Cardiothorac Surg. 2002 Aug; 22(2):330-1; author reply 331.
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  198. LeMaire SA, Schmittling ZC, Coselli JS, Undar A, Deady BA, Clubb FJ, Fraser CD. BioGlue surgical adhesive impairs aortic growth and causes anastomotic strictures. Ann Thorac Surg. 2002 May; 73(5):1500-5; discussion 1506.
    View in: PubMed
  199. Undar A, Koudieh MS, Fraser CD. Precise quantification of pulsatile flow. Ann Thorac Surg. 2002 Apr; 73(4):1358; author reply 1358-9.
    View in: PubMed
  200. Ündar A. . The ABCs of research on pulsatile versus nonpulsatile perfusion during cardiopulmonary bypass [Invited Editorial]. Medical Science Monitor. 2002; 8(12):ED21-ED24. .
  201. Undar A, Masai T, Yang SQ, Eichstaedt HC, McGarry MC, Vaughn WK, Fraser CD. Pulsatile perfusion improves regional myocardial blood flow during and after hypothermic cardiopulmonary bypass in a neonatal piglet model. ASAIO J. 2002 Jan-Feb; 48(1):90-5.
    View in: PubMed
  202. Undar A, Fraser CD. Change in vasoconstrictive function during left heart bypass. Artif Organs. 2001 Dec; 25(12):1022-4.
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  203. Undar A. Did Undar and associates really make those comments on the issue of pulsatile versus nonpulsatile flow? Absolutely not. ASAIO J. 2001 Nov-Dec; 47(6):699-702.
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  204. Undar A, Masai T, Yang SQ, Eichstaedt HC, McGarry MC, Vaughn WK, Goddard-Finegold J, Fraser CD. Global and regional cerebral blood flow in neonatal piglets undergoing pulsatile cardiopulmonary bypass with continuous perfusion at 25 degrees C and circulatory arrest at 18 degrees C. Perfusion. 2001 Nov; 16(6):503-10.
    View in: PubMed
  205. Undar A, Eichstaedt HC, Masai T, Yang SQ, Bigley JE, McGarry MC, Mueller M, Vaughn WK, Fraser CD. Comparison of six pediatric cardiopulmonary bypass pumps during pulsatile and nonpulsatile perfusion. J Thorac Cardiovasc Surg. 2001 Oct; 122(4):827-9.
    View in: PubMed
  206. Fung M, Loubser PG, Undar A, Mueller M, Sun C, Sun WN, Vaughn WK, Fraser CD. Inhibition of complement, neutrophil, and platelet activation by an anti-factor D monoclonal antibody in simulated cardiopulmonary bypass circuits. J Thorac Cardiovasc Surg. 2001 Jul; 122(1):113-22.
    View in: PubMed
  207. Undar A, Fraser CD. Influence of pulsatile and nonpulsatile left heart bypass on the hormonal circadian rhythm. ASAIO J. 2001 May-Jun; 47(3):305-7.
    View in: PubMed
  208. Ündar A, Vaughn WK, Calhoon JH. . Effects of pulsatile versus nonpulsatile flow on cerebral hemodynamics during pediatric cardiopulmonary bypass with deep hypothermic circulatory arrest. Proceedings of the 23 Annual Conference of the IEEE Engineering in Medicine and Biology Society. 2001; 23:1-4.
  209. Undar A, Fraser CD. Effects of reduced pulse pressure on the cerebral metabolism during prolonged, nonpulsatile left heart bypass. Artif Organs. 2001 Jan; 25(1):72-3.
    View in: PubMed
  210. Fung M; Undar A; Eichstaedt HC; et al. . Novel anti-factor D monoclonal antibody inhibits complement and leukocyte activation in a baboon model of cardiopulmonary bypass. MOLECULAR IMMUNOLOGY. 2001; 38(2-3):90-90 .
  211. Undar A, Fraser CD. Recent advances in paediatric cardiopulmonary bypass. Perfusion. 2000 Jun; 15(3):261-2.
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  212. Undar A, Vaughn WK, Calhoon JH. The effects of cardiopulmonary bypass and deep hypothermic circulatory arrest on blood viscoelasticity and cerebral blood flow in a neonatal piglet model. Perfusion. 2000 Mar; 15(2):121-8.
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  213. Undar A, Koenig KM, Frazier OH, Fraser CD. Impact of membrane oxygenators on pulsatile versus nonpulsatile perfusion in a neonatal model. Perfusion. 2000 Mar; 15(2):111-20.
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  214. Loubser PG; Fung M; Undar A; et al. . Inhibition of complement, neutrophil and platelet activation by an anti-factor D antibody during extracorporeal circulation. ANESTHESIOLOGY. 2000; 93(3A):U172-U172 .
  215. Undar A; Loubser PG; Fung M; et al. . Use of a new anti-factor D monoclonal antibody to suppress complement, neutrophil, platelet, and cytokine activation during cardiopulmonary bypass. CIRCULATION. 2000; 102(18):468-468 .
  216. Undar A, Eichstaedt HC, Frazier OH, Fraser CD. Monitoring regional cerebral oxygen saturation using near-infrared spectroscopy during pulsatile hypothermic cardiopulmonary bypass in a neonatal piglet model. ASAIO J. 2000 Jan-Feb; 46(1):103-6.
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  217. Undar A, Fraser CD. Physiology of nonpulsatile circulation: acute versus chronic support. ASAIO J. 2000 Jan-Feb; 46(1):150.
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  218. Undar A, Fraser CD. Balloon pump-induced pulsatile perfusion during cardiopulmonary bypass does not improve brain oxygenation. J Thorac Cardiovasc Surg. 2000 Jan; 119(1):189-90.
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  219. Undar A, Masai T, Frazier OH, Fraser CD. Pulsatile and nonpulsatile flows can be quantified in terms of energy equivalent pressure during cardiopulmonary bypass for direct comparisons. ASAIO J. 1999 Nov-Dec; 45(6):610-4.
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  220. Undar A, Masai T, Yang SQ, Goddard-Finegold J, Frazier OH, Fraser CD. Effects of perfusion mode on regional and global organ blood flow in a neonatal piglet model. Ann Thorac Surg. 1999 Oct; 68(4):1336-42; discussion 1342-3.
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  221. Undar A, Frazier OH, Fraser CD. Defining pulsatile perfusion: quantification in terms of energy equivalent pressure. Artif Organs. 1999 Aug; 23(8):712-6.
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  222. Undar A, Henderson N, Thurston GB, Masai T, Beyer EA, Frazier OH, Fraser CD. The effects of pulsatile versus nonpulsatile perfusion on blood viscoelasticity before and after deep hypothermic circulatory arrest in a neonatal piglet model. Artif Organs. 1999 Aug; 23(8):717-21.
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  223. Kameneva MV, Undar A, Antaki JF, Watach MJ, Calhoon JH, Borovetz HS. Decrease in red blood cell deformability caused by hypothermia, hemodilution, and mechanical stress: factors related to cardiopulmonary bypass. ASAIO J. 1999 Jul-Aug; 45(4):307-10.
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  224. Undar A, Andropoulos DB, Fraser CD. Comparison of pH-stat and alpha-stat cardiopulmonary bypass on cerebral oxygenation and blood flow in relation to hypothermic circulatory arrest in piglets. Anesthesiology. 1999 Mar; 90(3):926-7.
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  225. Undar A, Masai T, Inman R, Beyer EA, Mueller MA, McGarry MC, Frazier OH, Fraser CD. Evaluation of a physiologic pulsatile pump system for neonate-infant cardiopulmonary bypass support. ASAIO J. 1999 Jan-Feb; 45(1):53-8.
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  226. Undar A, Fraser CD. Influence of membrane oxygenators on the pulsatile flow in extracorporeal circuits: an experimental analysis. Int J Artif Organs. 1998 Nov; 21(11):714-5.
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  227. Undar A, Holland MC, Howelton RV, Benson CK, Ybarra JR, Miller OL, Rossbach MM, Runge TM, Johnson SB, Sako EY, Calhoon JH. Testing neonate-infant membrane oxygenators with the University of Texas neonatal pulsatile cardiopulmonary bypass system in vitro. Perfusion. 1998 Sep; 13(5):346-52.
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  228. Undar A, Fraser CD. The relation between pump flow rate and pulsatility on cerebral hemodynamics during pediatric cardiopulmonary bypass. J Thorac Cardiovasc Surg. 1998 Sep; 116(3):530-1.
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  229. Undar A, Lodge AJ, Daggett CW, Runge TM, Ungerleider RM, Calhoon JH. The type of aortic cannula and membrane oxygenator affect the pulsatile waveform morphology produced by a neonate-infant cardiopulmonary bypass system in vivo. Artif Organs. 1998 Aug; 22(8):681-6.
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  230. Undar A, Johnson SB, Calhoon JH. Comparison of pulsatile versus nonpulsatile perfusion on the postcardiopulmonary bypass aortic-radial artery pressure gradient. J Cardiothorac Vasc Anesth. 1998 Jun; 12(3):376-7.
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  231. Undar A, Calhoon JH. Stöckert roller pump generated pulsatile flow: cerebral metabolic changes in adult cardiopulmonary bypass. Perfusion. 1998 May; 13(3):215-6.
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  232. Undar A, Fraser CD. Influence of membrane oxygenators on the pulsatile flow in extracorporeal circuits: an experimental analysis. Int J Artif Organs. 1998 Mar; 21(3):179-80.
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  233. Undar A, Calhoon JH, Cossman RM, Johnson SB. The effects of pulsatile cardiopulmonary bypass on cerebral and renal blood flow in dogs. J Cardiothorac Vasc Anesth. 1998 Feb; 12(1):126-8.
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  234. Undar A, Helfrich CM, Johnson SB, Calhoon JH. Temperature during cardiopulmonary bypass for coronary artery operations does not influence postoperative cognitive function: a prospective, randomized trial. J Thorac Cardiovasc Surg. 1998 Feb; 115(2):482-4.
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  235. Undar A, Lodge AJ, Daggett CW, Runge TM, Ungerleider RM, Calhoon JH. Error associated with the choice of an aortic cannula in measuring regional cerebral blood flow with microspheres during pulsatile CPB in a neonatal piglet model. ASAIO J. 1997 Sep-Oct; 43(5):M482-6.
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  236. Lodge AJ, Undar A, Daggett CW, Runge TM, Calhoon JH, Ungerleider RM. Regional blood flow during pulsatile cardiopulmonary bypass and after circulatory arrest in an infant model. Ann Thorac Surg. 1997 May; 63(5):1243-50.
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  237. Ündar A, Holland MC, Howelton RV, Benson CK, Ybarra JR, Miller OL, Runge TM, Johnson SB, Sako EY, Calhoon JH. . Testing neonate-infant membrane oxygenators with the University of Texas pulsatile cardiopulmonary bypass system in vitro. [Synopsis]. Proceedings of the American Academy of Cardiovascular Perfusion. 1997; 18:107-109.
  238. Undar A, Lodge AJ, Runge TM, Daggett CW, Ungerleider RM, Calhoon JH. Design and performance of a physiologic pulsatile flow neonate-infant cardiopulmonary bypass system. ASAIO J. 1996 Sep-Oct; 42(5):M580-3.
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  239. Ündar A. Design and performance of physiologic pulsatile flow cardiopulmonary bypass systems for neonates and infants. Ph.D. Dissertation,. The University of Texas at Austin. 1996; 1-343..
  240. Undar A, Runge TM, Miller OL, Felger MC, Lansing R, Korvick DL, Bohls FO, Ottmers SE, O'Dell BJ, Ybarra JR, Howelton RV, Mireles RZ, Benson CK, Holland MC, Calhoon JH. Design of a physiologic pulsatile flow cardiopulmonary bypass system for neonates and infants. Int J Artif Organs. 1996 Mar; 19(3):170-6.
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