PSU Profiles
Last Name

Jiangang (Jason) Liao

InstitutionCollege of Medicine
DepartmentPublic Health Sciences
Address500 University Drive Hershey PA 17033
Mailbox: A210
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    Professor of Public Health Sciences


    Ph.D. in Biostatistics, Johns Hopkins University, 1993
    M.S. in Biostatistics, Chinese Academy of Preventive Medicine, 1986


    Biostatistics, Bioinformatics, Cancer research
    My Statistical Methodology Research Page

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Abdulghani J, Gokare P, Gallant JN, Dicker D, Whitcomb T, Cooper T, Liao J, Derr J, Liu J, Goldenberg D, Finnberg NK, El-Deiry WS. Sorafenib and Quinacrine Target Anti-Apoptotic Protein MCL1: A Poor Prognostic Marker in Anaplastic Thyroid Cancer (ATC). Clin Cancer Res. 2016 Dec 15; 22(24):6192-6203. PMID: 27307592.
      View in: PubMed
    2. Alsubai J, Matters GL, McGovern CO, Liao J, Gilius EL, Smith JP. Germline Mutation of the CCK Receptor: A Novel Biomarker for Pancreas Cancer. Clin Transl Gastroenterol. 2016 Jan 07; 7:e134. PMID: 26741064; PMCID: PMC4737870.
    3. He F, Bixler EO, Liao J, Berg A, Imamura Kawasawa Y, Fernandez-Mendoza J, Vgontzas AN, Liao D. Habitual sleep variability, mediated by nutrition intake, is associated with abdominal obesity in adolescents. Sleep Med. 2015 Dec; 16(12):1489-94. PMID: 26611945; PMCID: PMC4662770 [Available on 12/01/16].
    4. Smith JP, Whitcomb DC, Matters GL, Brand RE, Liao J, Huang YJ, Frazier ML. Distribution of cholecystokinin-B receptor genotype between patients with pancreatic cancer and controls and its impact on survival. Pancreas. 2015 Mar; 44(2):236-42. PMID: 25469546; PMCID: PMC4326549.
    5. Smith JP, Cooper TK, McGovern CO, Gilius EL, Zhong Q, Liao J, Molinolo AA, Gutkind JS, Matters GL. Cholecystokinin receptor antagonist halts progression of pancreatic cancer precursor lesions and fibrosis in mice. Pancreas. 2014 Oct; 43(7):1050-9. PMID: 25058882; PMCID: PMC4161619.
    6. Richie JP, Das A, Calcagnotto AM, Sinha R, Neidig W, Liao J, Lengerich EJ, Berg A, Hartman TJ, Ciccarella A, Baker A, Kaag MG, Goodin S, DiPaola RS, El-Bayoumy K. Comparative effects of two different forms of selenium on oxidative stress biomarkers in healthy men: a randomized clinical trial. Cancer Prev Res (Phila). 2014 Aug; 7(8):796-804. PMID: 24938534; PMCID: PMC4125492.
    7. Matters GL, Cooper TK, McGovern CO, Gilius EL, Liao J, Barth BM, Kester M, Smith JP. Cholecystokinin mediates progression and metastasis of pancreatic cancer associated with dietary fat. Dig Dis Sci. 2014 Jun; 59(6):1180-91. PMID: 24817409; PMCID: PMC4096234.
    8. Ashmore JH, Lesko SM, Miller PE, Cross AJ, Muscat JE, Zhu J, Liao J, Harper G, Lazarus P, Hartman TJ. Association of dietary and supplemental iron and colorectal cancer in a population-based study. Eur J Cancer Prev. 2013 Nov; 22(6):506-11. PMID: 23492957.
      View in: PubMed
    9. Liao JG, McMurry T, Berg A. Prior robust empirical Bayes inference for large-scale data by conditioning on rank with application to microarray data. Biostatistics. 2014 Jan; 15(1):60-73. PMID: 23934072; PMCID: PMC3862209.
    10. Olson J, Talekar M, Sachdev M, Castellani W, De la Cruz N, Davis J, Liao J, George M. Potassium changes associated with blood transfusion in pediatric patients. Am J Clin Pathol. 2013 Jun; 139(6):800-5. PMID: 23690124.
      View in: PubMed
    11. Takahashi Y, Hori T, Cooper TK, Liao J, Desai N, Serfass JM, Young MM, Park S, Izu Y, Wang HG. Bif-1 haploinsufficiency promotes chromosomal instability and accelerates Myc-driven lymphomagenesis via suppression of mitophagy. Blood. 2013 Feb 28; 121(9):1622-32. PMID: 23287860; PMCID: PMC3587325.
    12. Watters RJ, Fox TE, Tan SF, Shanmugavelandy S, Choby JE, Broeg K, Liao J, Kester M, Cabot MC, Loughran TP, Liu X. Targeting glucosylceramide synthase synergizes with C6-ceramide nanoliposomes to induce apoptosis in natural killer cell leukemia. Leuk Lymphoma. 2013 Jun; 54(6):1288-96. PMID: 23181473; PMCID: PMC4296321.
    13. Talamo G, Liao J, Joudeh J, Lamparella NE, Dinh H, Malysz J, Ehmann WC. Perceived levels of pain associated with bone marrow aspirates and biopsies. J Support Oncol. 2012 Jul-Aug; 10(4):166-70. PMID: 22621791.
      View in: PubMed
    14. Nichenametla SN, Muscat JE, Liao JG, Lazarus P, Richie JP. A functional trinucleotide repeat polymorphism in the 5'-untranslated region of the glutathione biosynthetic gene GCLC is associated with increased risk for lung and aerodigestive tract cancers. Mol Carcinog. 2013 Oct; 52(10):791-9. PMID: 22610501; PMCID: PMC3595361.
    15. Cheng Y, Sk UH, Zhang Y, Ren X, Zhang L, Huber-Keener KJ, Sun YW, Liao J, Amin S, Sharma AK, Yang JM. Rational incorporation of selenium into temozolomide elicits superior antitumor activity associated with both apoptotic and autophagic cell death. PLoS One. 2012; 7(4):e35104. PMID: 22496897; PMCID: PMC3320619.
    16. Nyland SB, Krissinger DJ, Clemente MJ, Irby RB, Baab KT, Jarbadan NR, Sokol L, Schaefer E, Liao J, Cuthbertson D, Epling-Burnette P, Paquette R, List AF, Maciejewski JP, Loughran TP. Seroreactivity to LGL leukemia-specific epitopes in aplastic anemia, myelodysplastic syndrome and paroxysmal nocturnal hemoglobinuria: results of a bone marrow failure consortium study. Leuk Res. 2012 May; 36(5):581-7. PMID: 22386729; PMCID: PMC3312981.
    17. Smith JP, Harms JF, Matters GL, McGovern CO, Ruggiero FM, Liao J, Fino KK, Ortega EE, Gilius EL, Phillips JA. A single nucleotide polymorphism of the cholecystokinin-B receptor predicts risk for pancreatic cancer. Cancer Biol Ther. 2012 Feb 01; 13(3):164-74. PMID: 22277584; PMCID: PMC3336072.
    18. Qi J, Rice SJ, Salzberg AC, Runkle EA, Liao J, Zander DS, Mu D. MiR-365 regulates lung cancer and developmental gene thyroid transcription factor 1. Cell Cycle. 2012 Jan 01; 11(1):177-86. PMID: 22185756; PMCID: PMC3272236.
    19. Cheng Y, Zhang Y, Zhang L, Ren X, Huber-Keener KJ, Liu X, Zhou L, Liao J, Keihack H, Yan L, Rubin E, Yang JM. MK-2206, a novel allosteric inhibitor of Akt, synergizes with gefitinib against malignant glioma via modulating both autophagy and apoptosis. Mol Cancer Ther. 2012 Jan; 11(1):154-64. PMID: 22057914; PMCID: PMC3302182.
    20. Kline CL, Sheikh HS, Scicchitano A, Gingrich R, Beachler C, Finnberg NK, Liao J, Sivik J, El-Deiry WS. Preliminary observations indicate variable patterns of plasma 5-fluorouracil (5-FU) levels during dose optimization of infusional 5-FU in colorectal cancer patients. Cancer Biol Ther. 2011 Oct 01; 12(7):557-68. PMID: 21931273.
      View in: PubMed
    21. Manni A, Xu H, Washington S, Aliaga C, Das A, Cooper T, Richie JP, Prokopczyk B, Calcagnotto A, Trushin N, Van den Heuvel JP, Hamilton C, Demers LM, Liao J, Verderame MF, El-Bayoumy K. The effects of Tamoxifen and fish oil on mammary carcinogenesis in polyoma middle T transgenic mice. Horm Cancer. 2011 Aug; 2(4):249-59. PMID: 21769696.
      View in: PubMed
    22. Manni A, Richie JP, Xu H, Washington S, Aliaga C, Cooper TK, Bruggeman R, Das A, Prokopczyk B, Calcagnotto A, Trushin N, Dickinson R, Liao J, Verderame MF, El-Bayoumy K. Effects of fish oil and Tamoxifen on preneoplastic lesion development and biomarkers of oxidative stress in the early stages of N-methyl-N-nitrosourea-induced rat mammary carcinogenesis. Int J Oncol. 2011 Nov; 39(5):1153-64. PMID: 21892590.
      View in: PubMed
    23. Liao A, Broeg K, Fox T, Tan SF, Watters R, Shah MV, Zhang LQ, Li Y, Ryland L, Yang J, Aliaga C, Dewey A, Rogers A, Loughran K, Hirsch L, Jarbadan NR, Baab KT, Liao J, Wang HG, Kester M, Desai D, Amin S, Loughran TP, Liu X. Therapeutic efficacy of FTY720 in a rat model of NK-cell leukemia. Blood. 2011 Sep 08; 118(10):2793-800. PMID: 21768294; PMCID: PMC3172796.
    24. Bortner JD, Richie JP, Das A, Liao J, Umstead TM, Stanley A, Stanley BA, Belani CP, El-Bayoumy K. Proteomic profiling of human plasma by iTRAQ reveals down-regulation of ITI-HC3 and VDBP by cigarette smoking. J Proteome Res. 2011 Mar 04; 10(3):1151-9. PMID: 21186835.
      View in: PubMed
    25. Talamo G, Farooq U, Zangari M, Liao J, Dolloff NG, Loughran TP, Epner E. Beyond the CRAB symptoms: a study of presenting clinical manifestations of multiple myeloma. Clin Lymphoma Myeloma Leuk. 2010 Dec; 10(6):464-8. PMID: 21156463.
      View in: PubMed
    26. Huh SJ, Chen YL, Friedman SL, Liao J, Huang HJ, Cavenee WK, Robertson GP. KLF6 Gene and early melanoma development in a collagen I-rich extracellular environment. J Natl Cancer Inst. 2010 Aug 04; 102(15):1131-47. PMID: 20660366; PMCID: PMC2914760.
    27. Belani CP, Liao J. Maintenance therapy for non-small-cell lung cancer. Lancet. 2010 Jan 23; 375(9711):281-2. PMID: 20109952.
      View in: PubMed
    28. Talamo G, Liao J, Bayerl MG, Claxton DF, Zangari M. Oral administration of analgesia and anxiolysis for pain associated with bone marrow biopsy. Support Care Cancer. 2010 Mar; 18(3):301-5. PMID: 19455356.
      View in: PubMed
    29. Chen KW, Perlman A, Liao JG, Lam A, Staller J, Sigal LH. Effects of external qigong therapy on osteoarthritis of the knee. A randomized controlled trial. Clin Rheumatol. 2008 Dec; 27(12):1497-505. PMID: 18654733; PMCID: PMC2582590.
    30. Cerynik DL, Ewald TJ, Sastry A, Amin NH, Liao JG, Tom JA. Outcomes of isolated glenoid labral injuries in professional baseball pitchers. Clin J Sport Med. 2008 May; 18(3):255-8. PMID: 18469567.
      View in: PubMed
    31. Liao JG, Chin KV. Logistic regression for disease classification using microarray data: model selection in a large p and small n case. Bioinformatics. 2007 Aug 01; 23(15):1945-51. PMID: 17540680.
      View in: PubMed
    32. Hagendorf BA, Liao JG, Price MR, Burd RS. Evaluation of race and insurance status as predictors of undergoing laparoscopic appendectomy in children. Ann Surg. 2007 Jan; 245(1):118-25. PMID: 17197974; PMCID: PMC1867949.
    33. Lasser MS, Liao JG, Burd RS. National trends in the use of antireflux procedures for children. Pediatrics. 2006 Nov; 118(5):1828-35. PMID: 17079551.
      View in: PubMed
    34. Dickstein RJ, Barone JG, Liao JG, Burd RS. The effect of surgeon volume and hospital characteristics on in-hospital outcome after ureteral reimplantation in children. Pediatr Surg Int. 2006 May; 22(5):417-21. PMID: 16609897.
      View in: PubMed
    35. Ly DP, Liao JG, Burd RS. Effect of surgeon and hospital characteristics on outcome after pyloromyotomy. Arch Surg. 2005 Dec; 140(12):1191-7. PMID: 16365241.
      View in: PubMed
    36. Cotton BA, Liao JG, Burd RS. The utility of clinical and laboratory data for predicting intraabdominal injury among children. J Trauma. 2005 Jun; 58(6):1306-7. PMID: 15995491.
      View in: PubMed
    37. Liao JG, Lin Y, Selvanayagam ZE, Shih WJ. A mixture model for estimating the local false discovery rate in DNA microarray analysis. Bioinformatics. 2004 Nov 01; 20(16):2694-701. PMID: 15145810.
      View in: PubMed
    38. Schoenwald SK, Sheidow AJ, Letourneau EJ, Liao JG. Transportability of multisystemic therapy: evidence for multilevel influences. Ment Health Serv Res. 2003 Dec; 5(4):223-39. PMID: 14672501.
      View in: PubMed
    39. Wong YF, Selvanayagam ZE, Wei N, Porter J, Vittal R, Hu R, Lin Y, Liao J, Shih JW, Cheung TH, Lo KW, Yim SF, Yip SK, Ngong DT, Siu N, Chan LK, Chan CS, Kong T, Kutlina E, McKinnon RD, Denhardt DT, Chin KV, Chung TK. Expression genomics of cervical cancer: molecular classification and prediction of radiotherapy response by DNA microarray. Clin Cancer Res. 2003 Nov 15; 9(15):5486-92. PMID: 14654527.
      View in: PubMed
    40. Upadhyaya HP, Brady KT, Wharton M, Liao J. Psychiatric disorders and cigarette smoking among child and adolescent psychiatry inpatients. Am J Addict. 2003 Mar-Apr; 12(2):144-52. PMID: 12746089.
      View in: PubMed
    41. Upadhyaya HP, Brady KT, Liao J, Sethuraman G, Middaugh L, Wharton M, Sallee FR. Neuroendocrine and behavioral responses to dopaminergic agonists in adolescents with alcohol abuse. Psychopharmacology (Berl). 2003 Mar; 166(2):95-101. PMID: 12520313.
      View in: PubMed
    42. Muthén B, Brown CH, Masyn K, Jo B, Khoo ST, Yang CC, Wang CP, Kellam SG, Carlin JB, Liao J. General growth mixture modeling for randomized preventive interventions. Biostatistics. 2002 Dec; 3(4):459-75. PMID: 12933592.
      View in: PubMed
    43. Malcolm R, Liao J, Michel M, Cochran K, Pye W, Yeager D, Halushka PV. Amlodipine reduces blood pressure and headache frequency in cocaine-dependent outpatients. J Psychoactive Drugs. 2002 Oct-Dec; 34(4):415-9. PMID: 12562110.
      View in: PubMed
    44. Henggeler SW, Schoenwald SK, Liao JG, Letourneau EJ, Edwards DL. Transporting efficacious treatments to field settings: the link between supervisory practices and therapist fidelity in MST programs. J Clin Child Adolesc Psychol. 2002 Jun; 31(2):155-67. PMID: 12056100.
      View in: PubMed
    45. Liao JG. A hierarchical Bayesian model for combining multiple 2 x 2 tables using conditional likelihoods. Biometrics. 1999 Mar; 55(1):268-72. PMID: 11318166.
      View in: PubMed
    46. Brookmeyer R, Liao JG. Statistical modelling of the AIDS epidemic for forecasting health care needs. Biometrics. 1990 Dec; 46(4):1151-63. PMID: 2085630.
      View in: PubMed
    47. Brookmeyer R, Liao JG. The analysis of delays in disease reporting: methods and results for the acquired immunodeficiency syndrome. Am J Epidemiol. 1990 Aug; 132(2):355-65. PMID: 2372012.
      View in: PubMed
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