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Heath Mackley

TitleAssociate Professor
InstitutionCollege of Medicine
DepartmentRadiology
Address500 University Drive Hershey PA 17033
Phone7175311523
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    Collapse Overview 
    Collapse overview
    PREFERRED TITLE/ROLE:



    Physician, Associate Professor of Radiology, Medicine, and Pediatrics



    EDUCATION:



    Residency, Radiation Oncology, Cleveland Clinic Foundation (Ohio) (2007)

    M.D., University of Pennsylvania School of Medicine (2002)



    NARRATIVE:



    Dr. Mackley's main focus is treating cancer patients, but he is also actively involved in education and research. He is the educational liaison for the Division of Radiation Oncology, and teaches and mentors medical students, residents, and fellows. He is currently involved in various research projects, including investigator initiated clinical trials, national clinical trials, translational research, and population research.


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Tchelebi L, Zaorsky N, Mackley H. Stereotactic Body Radiation Therapy in the Management of Upper GI Malignancies. Biomedicines. 2018 Jan 03; 6(1). PMID: 29301352.
      View in: PubMed
    2. Liu J, Goldenberg D, Almokadem S, Crist H, Mackley HB. Long-term recurrence-free survival after an unplanned reduction in radiotherapy for HPV-positive oropharyngeal SCC: Two cases and a review of the literature. Ear Nose Throat J. 2017 Jul; 96(7):E23-E27. PMID: 28719715.
      View in: PubMed
    3. Koller KM, Mackley HB, Liu J, Wagner H, Talamo G, Schell TD, Pameijer C, Neves RI, Anderson B, Kokolus KM, Mallon CA, Drabick JJ. Improved survival and complete response rates in patients with advanced melanoma treated with concurrent ipilimumab and radiotherapy versus ipilimumab alone. Cancer Biol Ther. 2017 01 02; 18(1):36-42. PMID: 27905824.
      View in: PubMed
    4. Baker A, Camacho F, Andrews G, Mackley H. A retrospective analysis of the role of adjuvant radiotherapy in the treatment of cutaneous melanoma. Cancer Biol Ther. 2016 Aug 15; 1-5. PMID: 27636187.
      View in: PubMed
    5. Yin M, Mackley HB, Drabick JJ, Harvey HA. Primary female breast sarcoma: clinicopathological features, treatment and prognosis. Sci Rep. 2016 Aug 11; 6:31497. PMID: 27510467; PMCID: PMC4980597.
    6. Koller KM, Wang W, Schell TD, Cozza EM, Kokolus KM, Neves RI, Mackley HB, Pameijer C, Leung A, Anderson B, Mallon CA, Robertson G, Drabick JJ. Malignant melanoma-The cradle of anti-neoplastic immunotherapy. Crit Rev Oncol Hematol. 2016 Oct; 106:25-54. PMID: 27637351.
      View in: PubMed
    7. Al-Marrawi MY, Mackley HB, Ali S, Wagner H, Joshi M, Holder S, Kaag M, Mallon C, Talamo G, Drabick JJ. Consolidation With Radiation or Concurrent Chemo-Radiation After Chemotherapy Results in Durable Complete Remissions of Isolated Nodal Recurrences of Urothelial Cancer: A Case Series and Review. Clin Genitourin Cancer. 2016 08; 14(4):e393-9. PMID: 26877063.
      View in: PubMed
    8. Baker MJ, Goldstein AM, Gordon PL, Harbaugh KS, Mackley HB, Glantz MJ, Drabick JJ. An interstitial deletion within 9p21.3 and extending beyond CDKN2A predisposes to melanoma, neural system tumours and possible haematological malignancies. J Med Genet. 2016 Jan 21. PMID: 26794401.
      View in: PubMed
    9. Enomoto LM, Schaefer EW, Goldenberg D, Mackley H, Koch WM, Hollenbeak CS. The Cost of Hospice Services in Terminally Ill Patients With Head and Neck Cancer. JAMA Otolaryngol Head Neck Surg. 2015 Dec; 141(12):1066-74. PMID: 26447873.
      View in: PubMed
    10. Short PF, Moran JR, Yang TC, Camacho F, Gusani NJ, Mackley HB, Matthews SA, Anderson RT. Effects of Hospital Type and Distance on Lymph Node Assessment for Colon Cancer Among Metropolitan and Nonmetropolitan Patients in Appalachia. Med Care Res Rev. 2016 10; 73(5):546-64. PMID: 26613702.
      View in: PubMed
    11. Fleming ST, Mackley HB, Camacho F, Yao N, Gusani NJ, Seiber EE, Matthews SA, Yang TC, Hwang W. Patterns of Care for Metastatic Colorectal Cancer in Appalachia, and the Clinical, Sociodemographic, and Service Provider Determinants. J Rural Health. 2016; 32(2):113-24. PMID: 26241785.
      View in: PubMed
    12. Hollenbeak CS, Kulaylat AN, Mackley H, Koch W, Schaefer EW, Goldenberg D. Determinants of Medicare Costs for Elderly Patients With Oral Cavity and Pharyngeal Cancers. JAMA Otolaryngol Head Neck Surg. 2015 Jul; 141(7):628-35. PMID: 26042925.
      View in: PubMed
    13. Hess CB, Singer M, Khaku A, Malinou J, Juliano JJ, Varlotto JM, Wagner H, Liao J, Myers KR, Levine MP, Mackley HB. Optimal Frequency of Psychosocial Distress Screening in Radiation Oncology. J Oncol Pract. 2015 Jul; 11(4):298-302. PMID: 26188046.
      View in: PubMed
    14. Wyluda EJ, Cheng J, Schell TD, Haley JS, Mallon C, Neves RI, Robertson G, Sivik J, Mackley H, Talamo G, Drabick JJ. Durable complete responses off all treatment in patients with metastatic malignant melanoma after sequential immunotherapy followed by a finite course of BRAF inhibitor therapy. Cancer Biol Ther. 2015; 16(5):662-70. PMID: 25806780; PMCID: PMC4622667.
    15. Kimmick GG, Camacho F, Mackley HB, Kern T, Yao N, Matthews SA, Fleming S, Lipscomb J, Liao J, Hwang W, Anderson RT. Individual, Area, and Provider Characteristics Associated With Care Received for Stages I to III Breast Cancer in a Multistate Region of Appalachia. J Oncol Pract. 2015 01; 11(1):e9-e18. PMID: 25228530.
      View in: PubMed
    16. Goldenberg D, Mackley H, Koch W, Bann DV, Schaefer EW, Hollenbeak CS. Age and stage as determinants of treatment for oral cavity and oropharyngeal cancers in the elderly. Oral Oncol. 2014 Oct; 50(10):976-82. PMID: 25153476; PMCID: PMC4355916.
    17. Schaefer EW, Wilson MZ, Goldenberg D, Mackley H, Koch W, Hollenbeak CS. Effect of marriage on outcomes for elderly patients with head and neck cancer. Head Neck. 2015 May; 37(5):735-42. PMID: 24596027.
      View in: PubMed
    18. Jiang Y, Mackley HB, Kimchi ET, Zhu J, Gusani N, Kaifi J, Staveley-O'Carroll KF, Belani CP. Phase I dose escalation study of capecitabine and erlotinib concurrent with radiation in locally advanced pancreatic cancer. Cancer Chemother Pharmacol. 2014 Jul; 74(1):205-10. PMID: 24908435.
      View in: PubMed
    19. Mackley HB, Teslova T, Camacho F, Short PF, Anderson RT. Does rurality influence treatment decisions in early stage laryngeal cancer? J Rural Health. 2014; 30(4):406-11. PMID: 24654995.
      View in: PubMed
    20. Varlotto JM, Decamp MM, Flickinger JC, Lake J, Recht A, Belani CP, Reed MF, Toth JW, Mackley HB, Sciamanna CN, Lipton A, Ali SM, Mahraj RP, Gilbert CR, Yao N. Would screening for lung cancer benefit 75- to 84-year-old residents of the United States? Front Oncol. 2014; 4:37. PMID: 24639950; PMCID: PMC3945517.
    21. Lynch MC, Drabick JJ, Neves RI, Fox EJ, Mackley HB, Anderson BE. Palliative effect of capecitabine and cetuximab for refractory metastatic squamous cell carcinoma of the perineum in epidermodysplasia verruciformis. Skinmed. 2014 Jan-Feb; 12(1):54-6. PMID: 24720087.
      View in: PubMed
    22. Kline CL, Schiccitano A, Zhu J, Beachler C, Sheikh H, Harvey HA, Mackley HB, McKenna K, Staveley-O'Carroll K, Poritz L, Messaris E, Stewart D, Sivik J, El-Deiry WS. Personalized dosing via pharmacokinetic monitoring of 5-fluorouracil might reduce toxicity in early- or late-stage colorectal cancer patients treated with infusional 5-fluorouracil-based chemotherapy regimens. Clin Colorectal Cancer. 2014 Jun; 13(2):119-26. PMID: 24461492.
      View in: PubMed
    23. Anderson RT, Yang TC, Matthews SA, Camacho F, Kern T, Mackley HB, Kimmick G, Louis C, Lengerich E, Yao N. Breast cancer screening, area deprivation, and later-stage breast cancer in Appalachia: does geography matter? Health Serv Res. 2014 Apr; 49(2):546-67. PMID: 24117371; PMCID: PMC3976186.
    24. Fleming ST, Mackley HB, Camacho F, Seiber EE, Gusani NJ, Matthews SA, Liao J, Yang TC, Hwang W, Yao N. Clinical, sociodemographic, and service provider determinants of guideline concordant colorectal cancer care for Appalachian residents. J Rural Health. 2014; 30(1):27-39. PMID: 24383482; PMCID: PMC3882337.
    25. Yao N, Mackley HB, Anderson RT, Recht A. Survival after partial breast brachytherapy in elderly patients with nonmetastatic breast cancer. Brachytherapy. 2013 Jul-Aug; 12(4):293-302. PMID: 23477884; PMCID: PMC4196242.
    26. Kimmick GG, Camacho F, Hwang W, Mackley H, Stewart J, Anderson RT. Adjuvant Radiation and Outcomes After Breast Conserving Surgery in Publicly Insured Patients. J Geriatr Oncol. 2012 Apr 01; 3(2):138-146. PMID: 22712029.
      View in: PubMed
    27. Kaifi JT, Gusani NJ, Jiang Y, Mackley HB, Dye CE, Mathew A, Kimchi ET, Reed MF, Staveley-O'Carroll KF. Multidisciplinary management of early and locally advanced esophageal cancer. J Clin Gastroenterol. 2011 May-Jun; 45(5):391-9. PMID: 21301357.
      View in: PubMed
    28. Sohrabi S, Drabick JJ, Crist H, Goldenberg D, Sheehan JM, Mackley HB. Neoadjuvant concurrent chemoradiation for advanced esthesioneuroblastoma: a case series and review of the literature. J Clin Oncol. 2011 May 01; 29(13):e358-61. PMID: 21282533.
      View in: PubMed
    29. Jiang Y, Mackley H, Cheng H, Ajani JA. Use of K-Ras as a predictive biomarker for selecting anti-EGF receptor/pathway treatment. Biomark Med. 2010 Aug; 4(4):535-41. PMID: 20701442.
      View in: PubMed
    30. Jiang Y, Mackley H, Cheng H, Ajani JA. Anal carcinoma therapy: can we improve on 5-fluorouracil/mitomycin/radiotherapy? J Natl Compr Canc Netw. 2010 Jan; 8(1):135-44. PMID: 20064295.
      View in: PubMed
    31. Mackley HB, Adelstein JS, Reddy CA, Adelstein DJ, Rice TW, Saxton JP, Videtic GM. Choice of radiotherapy planning modality influences toxicity in the treatment of locally advanced esophageal cancer. J Gastrointest Cancer. 2008; 39(1-4):130-7. PMID: 19407936.
      View in: PubMed
    32. Mackley HB, Reddy CA, Lee SY, Harnisch GA, Mayberg MR, Hamrahian AH, Suh JH. Intensity-modulated radiotherapy for pituitary adenomas: the preliminary report of the Cleveland Clinic experience. Int J Radiat Oncol Biol Phys. 2007 Jan 01; 67(1):232-9. PMID: 17084541.
      View in: PubMed
    33. Mackley HB, Videtic GM. Primary carcinoid tumors of the lung: a role for radiotherapy. Oncology (Williston Park). 2006 Nov; 20(12):1537-43; discussion 1544-5, 1549. PMID: 17153907.
      View in: PubMed
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