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Douglas Leslie

TitleProfessor
InstitutionCollege of Medicine
DepartmentPublic Health Sciences
Address500 University Drive Hershey PA 17033
Mailbox: A210
Phone7175311259

 Overview 
 overview
PREFERRED TITLE/ROLE:

Professor of Public Health Sciences and Psychiatry
Chief, Division of Health Services and Behavioral Research
Director, Center for Applied Studies in Health Economics

EDUCATION:

Ph.D., Economics, Yale University, 1998
M.Phil., Economics, Yale University, 1993
M.A., Economics, Yale University, 1992

NARRATIVE:

Dr. Leslie is a health economist with considerable experience in the fields of health economics, health services research and pharmacoeconomics. His areas of study have included the effects of managed care and other fiscal pressures on patterns of service use and costs for the mentally ill, the quality of mental health care, adherence to treatment guidelines for individuals with schizophrenia, the cost-effectiveness of antipsychotic medications, and health care service use and costs associated with autism. Dr. Leslie has worked extensively with large administrative claims databases, including those from Medicaid, the Department of Veterans Affairs and private health insurers.


 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Safdar B, Dziura J, Bathulapalli H, Leslie DL, Skanderson M, Brandt C, Haskell SG. Chest pain syndromes are associated with high rates of recidivism and costs in young United States Veterans. BMC Fam Pract. 2015; 16:88.
    View in: PubMed
  2. Foy AJ, Liu G, Davidson WR, Sciamanna C, Leslie DL. Comparative effectiveness of diagnostic testing strategies in emergency department patients with chest pain: an analysis of downstream testing, interventions, and outcomes. JAMA Intern Med. 2015 Mar 1; 175(3):428-36.
    View in: PubMed
  3. Leslie DL, Milchak W, Gastfriend DR, Herschman PL, Bixler EO, Velott DL, Meyer RE. Effects of injectable extended-release naltrexone (XR-NTX) for opioid dependence on residential rehabilitation outcomes and early follow-up. Am J Addict. 2015 Apr; 24(3):265-70.
    View in: PubMed
  4. Kirby JS, Miller JJ, Adams DR, Leslie D. Health care utilization patterns and costs for patients with hidradenitis suppurativa. JAMA Dermatol. 2014 Sep; 150(9):937-44.
    View in: PubMed
  5. Lee YH, Liu G, Thiboutot DM, Leslie DL, Kirby JS. A retrospective analysis of the duration of oral antibiotic therapy for the treatment of acne among adolescents: investigating practice gaps and potential cost-savings. J Am Acad Dermatol. 2014 Jul; 71(1):70-6.
    View in: PubMed
  6. Wiechers IR, Leslie DL, Rosenheck RA. Prescribing of psychotropic medications to patients without a psychiatric diagnosis. Psychiatr Serv. 2013 Dec 1; 64(12):1243-8.
    View in: PubMed
  7. Schubart JR, Camacho F, Leslie D. Psychotropic medication trends among children and adolescents with autism spectrum disorder in the Medicaid program. Autism. 2014 Aug; 18(6):631-7.
    View in: PubMed
  8. Wang L, Mandell DS, Lawer L, Cidav Z, Leslie DL. Healthcare service use and costs for autism spectrum disorder: a comparison between medicaid and private insurance. J Autism Dev Disord. 2013 May; 43(5):1057-64.
    View in: PubMed
  9. Stein BD, Sorbero MJ, Goswami U, Schuster J, Leslie DL. Impact of a private health insurance mandate on public sector autism service use in Pennsylvania. J Am Acad Child Adolesc Psychiatry. 2012 Aug; 51(8):771-9.
    View in: PubMed
  10. Gore M, Sadosky A, Stacey BR, Tai KS, Leslie D. The burden of chronic low back pain: clinical comorbidities, treatment patterns, and health care costs in usual care settings. Spine (Phila Pa 1976). 2012 May 15; 37(11):E668-77.
    View in: PubMed
  11. Leslie DL, Rosenheck R. Off-label use of antipsychotic medications in Medicaid. Am J Manag Care. 2012 Mar; 18(3):e109-17.
    View in: PubMed
  12. Gore M, Tai KS, Sadosky A, Leslie D, Stacey BR. Use and costs of prescription medications and alternative treatments in patients with osteoarthritis and chronic low back pain in community-based settings. Pain Pract. 2012 Sep; 12(7):550-60.
    View in: PubMed
  13. Jablonski RA, Kolanowski A, Therrien B, Mahoney EK, Kassab C, Leslie DL. Reducing care-resistant behaviors during oral hygiene in persons with dementia. BMC Oral Health. 2011; 11:30.
    View in: PubMed
  14. Gore M, Sadosky A, Leslie D, Tai KS, Seleznick M. Patterns of therapy switching, augmentation, and discontinuation after initiation of treatment with select medications in patients with osteoarthritis. Clin Ther. 2011 Dec; 33(12):1914-31.
    View in: PubMed
  15. Leslie DL, Inouye SK. The importance of delirium: economic and societal costs. J Am Geriatr Soc. 2011 Nov; 59 Suppl 2:S241-3.
    View in: PubMed
  16. Gore M, Tai KS, Chandran A, Zlateva G, Leslie D. Clinical comorbidities, treatment patterns, and healthcare costs among patients with fibromyalgia newly prescribed pregabalin or duloxetine in usual care. J Med Econ. 2012; 15(1):19-31.
    View in: PubMed
  17. Gore M, Tai KS, Sadosky A, Leslie D, Stacey BR. Clinical comorbidities, treatment patterns, and direct medical costs of patients with osteoarthritis in usual care: a retrospective claims database analysis. J Med Econ. 2011; 14(4):497-507.
    View in: PubMed
  18. Druss BG, von Esenwein SA, Compton MT, Zhao L, Leslie DL. Budget impact and sustainability of medical care management for persons with serious mental illnesses. Am J Psychiatry. 2011 Nov; 168(11):1171-8.
    View in: PubMed
  19. Kolanowski AM, Fick DM, Litaker MS, Clare L, Leslie D, Boustani M. Study protocol for the recreational stimulation for elders as a vehicle to resolve delirium superimposed on dementia (Reserve For DSD) trial. Trials. 2011; 12:119.
    View in: PubMed
  20. Leslie DL, Goulet J, Skanderson M, Mattocks K, Haskell S, Brandt C. VA health care utilization and costs among male and female veterans in the year after service in Afghanistan and Iraq. Mil Med. 2011 Mar; 176(3):265-9.
    View in: PubMed
  21. Haskell SG, Mattocks K, Goulet JL, Krebs EE, Skanderson M, Leslie D, Justice AC, Yano EM, Brandt C. The burden of illness in the first year home: do male and female VA users differ in health conditions and healthcare utilization. Womens Health Issues. 2011 Jan-Feb; 21(1):92-7.
    View in: PubMed
  22. Wang L, Leslie DL. Health care expenditures for children with autism spectrum disorders in Medicaid. J Am Acad Child Adolesc Psychiatry. 2010 Nov; 49(11):1165-71.
    View in: PubMed
  23. Makarov DV, Loeb S, Landman AB, Nielsen ME, Gross CP, Leslie DL, Penson DF, Desai RA. Regional variation in total cost per radical prostatectomy in the healthcare cost and utilization project nationwide inpatient sample database. J Urol. 2010 Apr; 183(4):1504-9.
    View in: PubMed
  24. Busch SH, Frank RG, Leslie DL, Martin A, Rosenheck RA, Martin EG, Barry CL. Antidepressants and suicide risk: how did specific information in FDA safety warnings affect treatment patterns? Psychiatr Serv. 2010 Jan; 61(1):11-6.
    View in: PubMed
  25. Mohamed S, Rosenheck R, Harpaz-Rotem I, Leslie D, Sernyak MJ. Duration of pharmacotherapy with long-acting injectable risperidone in the treatment of schizophrenia. Psychiatr Q. 2009 Dec; 80(4):241-9.
    View in: PubMed
  26. Leslie DL, Mohamed S, Rosenheck RA. Off-label use of antipsychotic medications in the department of Veterans Affairs health care system. Psychiatr Serv. 2009 Sep; 60(9):1175-81.
    View in: PubMed
  27. Mohamed S, Leslie DL, Rosenheck RA. Use of antipsychotics in the treatment of major depressive disorder in the U.S. Department of Veterans Affairs. J Clin Psychiatry. 2009 Jun; 70(6):906-12.
    View in: PubMed
  28. Leslie DL, Kozma L, Martin A, Landeros A, Katsovich L, King RA, Leckman JF. Neuropsychiatric disorders associated with streptococcal infection: a case-control study among privately insured children. J Am Acad Child Adolesc Psychiatry. 2008 Oct; 47(10):1166-72.
    View in: PubMed
  29. Leslie DL, Rosenheck RA. Diversity versus concentration in antipsychotic drug selection. J Ment Health Policy Econ. 2008 Sep; 11(3):107-12.
    View in: PubMed
  30. Rosenheck RA, Leslie DL, Doshi JA. Policy implications of CATIE. Psychiatr Serv. 2008 Jun; 59(6):695.
    View in: PubMed
  31. Rosenheck RA, Leslie DL, Doshi JA. Second-generation antipsychotics: cost-effectiveness, policy options, and political decision making. Psychiatr Serv. 2008 May; 59(5):515-20.
    View in: PubMed
  32. Leslie DL, Marcantonio ER, Zhang Y, Leo-Summers L, Inouye SK. One-year health care costs associated with delirium in the elderly population. Arch Intern Med. 2008 Jan 14; 168(1):27-32.
    View in: PubMed
  33. Rosenheck RA, Leslie DL, Sindelar JL, Miller EA, Tariot PN, Dagerman KS, Davis SM, Lebowitz BD, Rabins P, Hsiao JK, Lieberman JA, Schneider LS. Cost-benefit analysis of second-generation antipsychotics and placebo in a randomized trial of the treatment of psychosis and aggression in Alzheimer disease. Arch Gen Psychiatry. 2007 Nov; 64(11):1259-68.
    View in: PubMed
  34. Rosenheck RA, Leslie DL, Busch S, Rofman ES, Sernyak M. Rethinking antipsychotic formulary policy. Schizophr Bull. 2008 Mar; 34(2):375-80.
    View in: PubMed
  35. McAvay GJ, Van Ness PH, Bogardus ST, Zhang Y, Leslie DL, Leo-Summers LS, Inouye SK. Depressive symptoms and the risk of incident delirium in older hospitalized adults. J Am Geriatr Soc. 2007 May; 55(5):684-91.
    View in: PubMed
  36. Leslie DL, Martin A. Health care expenditures associated with autism spectrum disorders. Arch Pediatr Adolesc Med. 2007 Apr; 161(4):350-5.
    View in: PubMed
  37. Rosenheck RA, Leslie DL, Sindelar J, Miller EA, Lin H, Stroup TS, McEvoy J, Davis SM, Keefe RS, Swartz M, Perkins DO, Hsiao JK, Lieberman J. Cost-effectiveness of second-generation antipsychotics and perphenazine in a randomized trial of treatment for chronic schizophrenia. Am J Psychiatry. 2006 Dec; 163(12):2080-9.
    View in: PubMed
  38. McAvay GJ, Van Ness PH, Bogardus ST, Zhang Y, Leslie DL, Leo-Summers LS, Inouye SK. Older adults discharged from the hospital with delirium: 1-year outcomes. J Am Geriatr Soc. 2006 Aug; 54(8):1245-50.
    View in: PubMed
  39. Rosenheck R, Leslie D, Keefe R, McEvoy J, Swartz M, Perkins D, Stroup S, Hsiao JK, Lieberman J. Barriers to employment for people with schizophrenia. Am J Psychiatry. 2006 Mar; 163(3):411-7.
    View in: PubMed
  40. Petrakis IL, Leslie D, Finney JW, Rosenheck R. Atypical antipsychotic medication and substance use-related outcomes in the treatment of schizophrenia. Am J Addict. 2006 Jan-Feb; 15(1):44-9.
    View in: PubMed
  41. Chwastiak L, Rosenheck R, Leslie D. Impact of medical comorbidity on the quality of schizophrenia pharmacotherapy in a national VA sample. Med Care. 2006 Jan; 44(1):55-61.
    View in: PubMed
  42. Hoblyn J, Noda A, Yesavage JA, Brooks JO, Sheikh J, Lee T, Tinklenberg JR, Schneider B, O'Hara R, Leslie DL, Rosenheck RA, Kraemer HC. Factors in choosing atypical antipsychotics: toward understanding the bases of physicians' prescribing decisions. J Psychiatr Res. 2006 Mar; 40(2):160-6.
    View in: PubMed
  43. Harpaz-Rotem I, Leslie DL, Martin A, Rosenheck RA. Changes in child and adolescent inpatient psychiatric admission diagnoses between 1995 and 2000. Soc Psychiatry Psychiatr Epidemiol. 2005 Aug; 40(8):642-7.
    View in: PubMed
  44. Leslie DL, Zhang Y, Holford TR, Bogardus ST, Leo-Summers LS, Inouye SK. Premature death associated with delirium at 1-year follow-up. Arch Intern Med. 2005 Jul 25; 165(14):1657-62.
    View in: PubMed
  45. Leslie DL, Rosenheck RA. Pharmacotherapy and health care costs among patients with schizophrenia and newly diagnosed diabetes. Psychiatr Serv. 2005 Jul; 56(7):803-9.
    View in: PubMed
  46. Miller EA, Leslie DL, Rosenheck RA. Incidence of new-onset diabetes mellitus among patients receiving atypical neuroleptics in the treatment of mental illness: evidence from a privately insured population. J Nerv Ment Dis. 2005 Jun; 193(6):387-95.
    View in: PubMed
  47. Leslie DL, Zhang Y, Bogardus ST, Holford TR, Leo-Summers LS, Inouye SK. Consequences of preventing delirium in hospitalized older adults on nursing home costs. J Am Geriatr Soc. 2005 Mar; 53(3):405-9.
    View in: PubMed
  48. Inouye SK, Leo-Summers L, Zhang Y, Bogardus ST, Leslie DL, Agostini JV. A chart-based method for identification of delirium: validation compared with interviewer ratings using the confusion assessment method. J Am Geriatr Soc. 2005 Feb; 53(2):312-8.
    View in: PubMed
  49. Sernyak MJ, Leslie D, Rosenheck R. Predictors of antipsychotic medication change. J Behav Health Serv Res. 2005 Jan-Mar; 32(1):85-94.
    View in: PubMed
  50. Busch SH, Leslie DL, Rosenheck RA. Comparing the quality of antidepressant pharmacotherapy in the Department of Veterans Affairs and the private sector. Psychiatr Serv. 2004 Dec; 55(12):1386-91.
    View in: PubMed
  51. Leslie DL, Rosenheck RA. Incidence of newly diagnosed diabetes attributable to atypical antipsychotic medications. Am J Psychiatry. 2004 Sep; 161(9):1709-11.
    View in: PubMed
  52. Harpaz-Rotem I, Leslie D, Rosenheck RA. Treatment retention among children entering a new episode of mental health care. Psychiatr Serv. 2004 Sep; 55(9):1022-8.
    View in: PubMed
  53. Martin A, Young C, Leckman JF, Mukonoweshuro C, Rosenheck R, Leslie D. Age effects on antidepressant-induced manic conversion. Arch Pediatr Adolesc Med. 2004 Aug; 158(8):773-80.
    View in: PubMed
  54. Busch SH, Leslie D, Rosenheck R. Measuring quality of pharmacotherapy for depression in a national health care system. Med Care. 2004 Jun; 42(6):532-42.
    View in: PubMed
  55. Leslie DL, Rosenheck RA. Adherence of schizophrenia pharmacotherapy to published treatment recommendations: patient, facility, and provider predictors. Schizophr Bull. 2004; 30(3):649-58.
    View in: PubMed
  56. Rosenheck R, Perlick D, Bingham S, Liu-Mares W, Collins J, Warren S, Leslie D, Allan E, Campbell EC, Caroff S, Corwin J, Davis L, Douyon R, Dunn L, Evans D, Frecska E, Grabowski J, Graeber D, Herz L, Kwon K, Lawson W, Mena F, Sheikh J, Smelson D, Smith-Gamble V. Effectiveness and cost of olanzapine and haloperidol in the treatment of schizophrenia: a randomized controlled trial. JAMA. 2003 Nov 26; 290(20):2693-702.
    View in: PubMed
  57. Petrakis IL, Leslie D, Rosenheck R. Use of naltrexone in the treatment of alcoholism nationally in the Department of Veterans Affairs. Alcohol Clin Exp Res. 2003 Nov; 27(11):1780-4.
    View in: PubMed
  58. Martin A, Leslie D. Trends in psychotropic medication costs for children and adolescents, 1997-2000. Arch Pediatr Adolesc Med. 2003 Oct; 157(10):997-1004.
    View in: PubMed
  59. Leslie DL, Rosenheck RA. Benchmarking the quality of schizophrenia pharmacotherapy: a comparison of the Department of Veterans Affairs and the private sector. J Ment Health Policy Econ. 2003 Sep; 6(3):113-21.
    View in: PubMed
  60. Rosenheck R, Leslie D. Administrative prescription review procedures and use of atypical antipsychotic medications in the Department of Veterans Affairs. Ment Health Serv Res. 2003 Sep; 5(3):149-53.
    View in: PubMed
  61. Petrakis IL, Leslie D, Rosenheck R. The use of antidepressants in alcohol-dependent veterans. J Clin Psychiatry. 2003 Aug; 64(8):865-70.
    View in: PubMed
  62. Sernyak MJ, Gulanski B, Leslie DL, Rosenheck R. Undiagnosed hyperglycemia in clozapine-treated patients with schizophrenia. J Clin Psychiatry. 2003 May; 64(5):605-8.
    View in: PubMed
  63. Rosenheck R, Leslie D, Woody G. Fiscal strain and access to opiate substitution therapy at Department of Veterans Affairs Medical Centers. Am J Addict. 2003 May-Jun; 12(3):220-8.
    View in: PubMed
  64. Martin A, Leslie D. Psychiatric inpatient, outpatient, and medication utilization and costs among privately insured youths, 1997-2000. Am J Psychiatry. 2003 Apr; 160(4):757-64.
    View in: PubMed
  65. Sernyak MJ, Leslie D, Rosenheck R. Use of system-wide outcomes monitoring data to compare the effectiveness of atypical neuroleptic medications. Am J Psychiatry. 2003 Feb; 160(2):310-5.
    View in: PubMed
  66. Rosenheck R, Doyle J, Leslie D, Fontana A. Changing environments and alternative perspectives in evaluating the cost-effectiveness of new antipsychotic drugs. Schizophr Bull. 2003; 29(1):81-93.
    View in: PubMed
  67. Martin A, Sherwin T, Stubbe D, Van Hoof T, Scahill L, Leslie D. Datapoints: use of multiple psychotropic drugs by Medicaid-insured and privately insured children. Psychiatr Serv. 2002 Dec; 53(12):1508.
    View in: PubMed
  68. Leslie DL, Rosenheck RA. From conventional to atypical antipsychotics and back: dynamic processes in the diffusion of new medications. Am J Psychiatry. 2002 Sep; 159(9):1534-40.
    View in: PubMed
  69. Sernyak MJ, Leslie DL, Alarcon RD, Losonczy MF, Rosenheck R. Association of diabetes mellitus with use of atypical neuroleptics in the treatment of schizophrenia. Am J Psychiatry. 2002 Apr; 159(4):561-6.
    View in: PubMed
  70. Leslie DL, Rosenheck RA. Use of pharmacy data to assess quality of pharmacotherapy for schizophrenia in a national health care system: individual and facility predictors. Med Care. 2001 Sep; 39(9):923-33.
    View in: PubMed
  71. Leslie DL, Rosenheck R. The effect of institutional fiscal stress on the use of atypical antipsychotic medications in the treatment of schizophrenia. J Nerv Ment Dis. 2001 Jun; 189(6):377-83.
    View in: PubMed
  72. Leslie DL, Rosenheck RA, Horwitz SM. Patterns of mental health utilization and costs among children in a privately insured population. Health Serv Res. 2001 Apr; 36(1 Pt 1):113-27.
    View in: PubMed
  73. Rosenheck R, Leslie D, Sernyak M. From clinical trials to real-world practice: use of atypical antipsychotic medication nationally in the Department of Veterans Affairs. Med Care. 2001 Mar; 39(3):302-8.
    View in: PubMed
  74. Leslie DL, Rosenheck RA. Comparing quality of mental health care for public-sector and privately insured populations. Psychiatr Serv. 2000 May; 51(5):650-5.
    View in: PubMed
  75. Striegel-Moore RH, Leslie D, Petrill SA, Garvin V, Rosenheck RA. One-year use and cost of inpatient and outpatient services among female and male patients with an eating disorder: evidence from a national database of health insurance claims. Int J Eat Disord. 2000 May; 27(4):381-9.
    View in: PubMed
  76. Rosenheck RA, Druss B, Stolar M, Leslie D, Sledge W. Effect of declining mental health service use on employees of a large corporation. Health Aff (Millwood). 1999 Sep-Oct; 18(5):193-203.
    View in: PubMed
  77. Leslie DL, Rosenheck R. Shifting to outpatient care? Mental health care use and cost under private insurance. Am J Psychiatry. 1999 Aug; 156(8):1250-7.
    View in: PubMed
  78. Leslie DL, Rosenheck R. Changes in inpatient mental health utilization and costs in a privately insured population, 1993 to 1995. Med Care. 1999 May; 37(5):457-68.
    View in: PubMed
  79. Leslie DL, Rosenheck R. Inpatient treatment of comorbid psychiatric and substance abuse disorders: comparison of public sector and privately insured populations. Adm Policy Ment Health. 1999 Mar; 26(4):253-68.
    View in: PubMed
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