|Institution||College of Medicine|
|Department||Cellular and Molecular Physiology|
|Address||500 University Drive Hershey PA 17033|
Associate Professor of Cellular and Molecular Physiology
SECONDARY APPOINTMENT(S)/ INSTITUTE(S)/ CENTER(S):
The Huck Institute of the Life Sciences
GRADUATE PROGRAM AFFILIATIONS:
Biomedical Sciences, Physiology, Cell and Developmental Biology, Molecular Medicine, Anatomy
Postdoctoral Training, University of Pennsylvania School of Medicine, 2000-2003
Ph.D., University of Vermont College of Medicine, 2000
My research group studies the structural, biochemical, and physiological properties of molecular motor and cytoskeletal proteins. We examine the structural mechanism of energy transduction in myosin motor proteins using spectroscopic, enzymatic, and biophysical methods. In addition, studies of uncharacterized non-muscle myosin proteins that function in vision, hearing, intracellular transport, and contractility are in progress. Defects in the myosin motors under investigation are associated with many different genetic diseases such as cardiomyopathies, cancer, deafness, and retinal degeneration. Other ongoing projects are focused on myosin-based regulation of the actin cytoskeleton in alveolar macrophages, inner ear hair cells, and photoreceptors.
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