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Yanming Wang

Address454 Frear North Lab
University Park, PA 16802
Phone8148653775

 Overview 
 overview
PREFERRED TITLE/ROLE:

Associate Professor of Biochemistry and Molecular Biology

GRADUATE PROGRAM AFFILIATIONS:

Cell and Developmental Biology, Genetics, Molecular Medicine

NARRATIVE:

Dr. Wang's research focuses on epigenetic histone modifications in cell differentiation and cancer, specifically the role of histone citrullination catalyzed by peptidylarginine deiminase 4 (PAD4) in transcriptional repression of tumor suppressor genes, as well as a unique role of histone hyper-citrullination in antibacterial innate immunity mediated by a highly decondensed chromatin structure termed neutrophil extracellular traps (NETs).


 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Wang Y, Li M, Stadler S, Correll S, Li P, Wang D, Hayama R, Leonelli L, Han H, Grigoryev SA, Allis CD, Coonrod SA. Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation. J Cell Biol. 2009 Jan 26; 184(2):205-13.
    View in: PubMed
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