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Clare Sample

TitleProfessor
InstitutionCollege of Medicine
DepartmentMicrobiology and Immunology
Address500 University Drive Hershey PA 17033
Mailbox: H107
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    Collapse Overview 
    Collapse overview
    PREFERRED TITLE/ROLE:
    Professor

    GRADUATE PROGRAM AFFILIATIONS:
    Biomedical Sciences
    Virology and Immunology (VIRIM) Option

    EDUCATION:
    Postdoctoral Training, University of Chicago, Department of Biochemistry and Molecular Biology
    Postdoctoral Training, Harvard Medical School, Department of Microbiology and Molecular Genetics
    Ph.D., University of South Florida College of Medicine, Department of Biochemistry
    MA, University of California Berkeley, Department of Biochemistry
    BA, Temple University (Biochemistry)


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Temple RM, Meyers C, Sample CE. Generation and Infection of Organotypic Cultures with Epstein-Barr Virus. Methods Mol Biol. 2017; 1532:65-78. PMID: 27873267.
      View in: PubMed
    2. Hasanali ZS, Epner EM, Feith DJ, Loughran TP, Sample CE. Vorinostat downregulates CD30 and decreases brentuximab vedotin efficacy in human lymphocytes. Mol Cancer Ther. 2014 Dec; 13(12):2784-92. PMID: 25319394; PMCID: PMC4258453.
    3. Temple RM, Zhu J, Budgeon L, Christensen ND, Meyers C, Sample CE. Efficient replication of Epstein-Barr virus in stratified epithelium in vitro. Proc Natl Acad Sci U S A. 2014 Nov 18; 111(46):16544-9. PMID: 25313069; PMCID: PMC4246336.
    4. Tursiella ML, Bowman ER, Wanzeck KC, Throm RE, Liao J, Zhu J, Sample CE. Epstein-Barr virus nuclear antigen 3A promotes cellular proliferation by repression of the cyclin-dependent kinase inhibitor p21WAF1/CIP1. PLoS Pathog. 2014 Oct; 10(10):e1004415. PMID: 25275486; PMCID: PMC4183747.
    5. Hughes DJ, Marendy EM, Dickerson CA, Yetming KD, Sample CE, Sample JT. Contributions of CTCF and DNA methyltransferases DNMT1 and DNMT3B to Epstein-Barr virus restricted latency. J Virol. 2012 Jan; 86(2):1034-45. PMID: 22072770; PMCID: PMC3255836.
    6. Hughes DJ, Dickerson CA, Shaner MS, Sample CE, Sample JT. trans-Repression of protein expression dependent on the Epstein-Barr virus promoter Wp during latency. J Virol. 2011 Nov; 85(21):11435-47. PMID: 21865378; PMCID: PMC3194970.
    7. Lockey TD, Zhan X, Surman S, Sample CE, Hurwitz JL. Epstein-Barr virus vaccine development: a lytic and latent protein cocktail. Front Biosci. 2008 May 01; 13:5916-27. PMID: 18508632.
      View in: PubMed
    8. Long SM, Sample CE. EBV-associated diseases in the AIDS patient. Cancer Treat Res. 2007; 133:163-83. PMID: 17672041.
      View in: PubMed
    9. Jiménez-Ramírez C, Brooks AJ, Forshell LP, Yakimchuk K, Zhao B, Fulgham TZ, Sample CE. Epstein-Barr virus EBNA-3C is targeted to and regulates expression from the bidirectional LMP-1/2B promoter. J Virol. 2006 Nov; 80(22):11200-8. PMID: 16956945; PMCID: PMC1642179.
    10. Zhao B, Dalbiès-Tran R, Jiang H, Ruf IK, Sample JT, Wang F, Sample CE. Transcriptional regulatory properties of Epstein-Barr virus nuclear antigen 3C are conserved in simian lymphocryptoviruses. J Virol. 2003 May; 77(10):5639-48. PMID: 12719556; PMCID: PMC154039.
    11. Ruvolo V, Navarro L, Sample CE, David M, Sung S, Swaminathan S. The Epstein-Barr virus SM protein induces STAT1 and interferon-stimulated gene expression. J Virol. 2003 Mar; 77(6):3690-701. PMID: 12610144; PMCID: PMC149524.
    12. Gottschalk S, Ng CY, Perez M, Smith CA, Sample C, Brenner MK, Heslop HE, Rooney CM. An Epstein-Barr virus deletion mutant associated with fatal lymphoproliferative disease unresponsive to therapy with virus-specific CTLs. Blood. 2001 Feb 15; 97(4):835-43. PMID: 11159505.
      View in: PubMed
    13. Dalbiès-Tran R, Stigger-Rosser E, Dotson T, Sample CE. Amino acids of Epstein-Barr virus nuclear antigen 3A essential for repression of Jkappa-mediated transcription and their evolutionary conservation. J Virol. 2001 Jan; 75(1):90-9. PMID: 11119577; PMCID: PMC113901.
    14. Zhao B, Sample CE. Epstein-barr virus nuclear antigen 3C activates the latent membrane protein 1 promoter in the presence of Epstein-Barr virus nuclear antigen 2 through sequences encompassing an spi-1/Spi-B binding site. J Virol. 2000 Jun; 74(11):5151-60. PMID: 10799590; PMCID: PMC110868.
    15. Parfenov VN, Davis DS, Pochukalina GN, Sample CE, Murti KG. Nuclear bodies of stage 6 oocytes of Rana temporaria contain nucleolar and coiled body proteins. Exp Cell Res. 1996 Nov 01; 228(2):229-36. PMID: 8912715.
      View in: PubMed
    16. Zhao B, Marshall DR, Sample CE. A conserved domain of the Epstein-Barr virus nuclear antigens 3A and 3C binds to a discrete domain of Jkappa. J Virol. 1996 Jul; 70(7):4228-36. PMID: 8676443; PMCID: PMC190353.
    17. Razzouk BI, Srinivas S, Sample CE, Singh V, Sixbey JW. Epstein-Barr Virus DNA recombination and loss in sporadic Burkitt's lymphoma. J Infect Dis. 1996 Mar; 173(3):529-35. PMID: 8627013.
      View in: PubMed
    18. Marshall D, Sample C. Epstein-Barr virus nuclear antigen 3C is a transcriptional regulator. J Virol. 1995 Jun; 69(6):3624-30. PMID: 7745710; PMCID: PMC189077.
    19. Wrightham MN, Stewart JP, Janjua NJ, Pepper SD, Sample C, Rooney CM, Arrand JR. Antigenic and sequence variation in the C-terminal unique domain of the Epstein-Barr virus nuclear antigen EBNA-1. Virology. 1995 Apr 20; 208(2):521-30. PMID: 7538250.
      View in: PubMed
    20. Parfenov VN, Davis DS, Pochukalina GN, Sample CE, Bugaeva EA, Murti KG. Nuclear actin filaments and their topological changes in frog oocytes. Exp Cell Res. 1995 Apr; 217(2):385-94. PMID: 7698240.
      View in: PubMed
    21. Sample C, Parker B. Biochemical characterization of Epstein-Barr virus nuclear antigen 3A and 3C proteins. Virology. 1994 Dec; 205(2):534-9. PMID: 7975254.
      View in: PubMed
    22. Sample J, Henson EB, Sample C. The Epstein-Barr virus nuclear protein 1 promoter active in type I latency is autoregulated. J Virol. 1992 Aug; 66(8):4654-61. PMID: 1321268; PMCID: PMC241289.
    23. Sample J, Brooks L, Sample C, Young L, Rowe M, Gregory C, Rickinson A, Kieff E. Restricted Epstein-Barr virus protein expression in Burkitt lymphoma is due to a different Epstein-Barr nuclear antigen 1 transcriptional initiation site. Proc Natl Acad Sci U S A. 1991 Jul 15; 88(14):6343-7. PMID: 1648738; PMCID: PMC52079.
    24. Sample C, Kieff E. Molecular basis for Epstein-Barr virus induced pathogenesis and disease. Springer Semin Immunopathol. 1991; 13(2):133-46. PMID: 1664982.
      View in: PubMed
    25. Petti L, Sample C, Kieff E. Subnuclear localization and phosphorylation of Epstein-Barr virus latent infection nuclear proteins. Virology. 1990 Jun; 176(2):563-74. PMID: 2161150.
      View in: PubMed
    26. Wang F, Gregory C, Sample C, Rowe M, Liebowitz D, Murray R, Rickinson A, Kieff E. Epstein-Barr virus latent membrane protein (LMP1) and nuclear proteins 2 and 3C are effectors of phenotypic changes in B lymphocytes: EBNA-2 and LMP1 cooperatively induce CD23. J Virol. 1990 May; 64(5):2309-18. PMID: 2157887; PMCID: PMC249392.
    27. Ness GC, Sukalski KA, Sample CE, Pendleton LC, McCreery MJ, Nordlie RC. Radiation inactivation analysis of rat liver microsomal glucose-6-phosphatase. J Biol Chem. 1989 May 05; 264(13):7111-4. PMID: 2540173.
      View in: PubMed
    28. Sanke T, Bell GI, Sample C, Rubenstein AH, Steiner DF. An islet amyloid peptide is derived from an 89-amino acid precursor by proteolytic processing. J Biol Chem. 1988 Nov 25; 263(33):17243-6. PMID: 3053705.
      View in: PubMed
    29. Sample CE, Steiner DF. Tissue-specific binding of a nuclear factor to the insulin gene promoter. FEBS Lett. 1987 Oct 05; 222(2):332-6. PMID: 3308516.
      View in: PubMed
    30. Sample CE, Pendleton LC, Ness GC. Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase mRNA levels by L-triiodothyronine. Biochemistry. 1987 Feb 10; 26(3):727-31. PMID: 3567145.
      View in: PubMed
    31. Sample CE, Ness GC. Regulation of the activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase by insulin. Biochem Biophys Res Commun. 1986 May 29; 137(1):201-7. PMID: 3521603.
      View in: PubMed
    32. Ness GC, Sample CE, Smith M, Pendleton LC, Eichler DC. Characteristics of rat liver microsomal 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Biochem J. 1986 Jan 01; 233(1):167-72. PMID: 3082322; PMCID: PMC1152999.
    33. Ness GC, McCreery MJ, Sample CE, Smith M, Pendleton LC. Sulfhydryl/disulfide forms of rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase. J Biol Chem. 1985 Dec 25; 260(30):16395-9. PMID: 4066714.
      View in: PubMed
    34. Phillips CE, Ness GC. Topography of rat liver microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase. Biochem Biophys Res Commun. 1984 Mar 15; 119(2):772-8. PMID: 6712656.
      View in: PubMed
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