PSU Profiles
Last Name

Prakasha Gowda Aladahalli Sanne Gowda

TitleResearch Associate
InstitutionCollege of Medicine
DepartmentBiochemistry and Molecular Biology
Address500 University Drive, Hershey, PA 17033
Mailbox: H171
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    Research Associate of Biochemistry and Molecular Biology


    2002 Ph. D. Chemistry, University of Mysore, Mysore, India

    1997 M. Sc. Biochemistry, University of Mysore, Mysore, India

    1991 B. Sc. Biology, University of Mysore, Mysore, India

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Gowda AS, Krishnegowda G, Suo Z, Amin S, Spratt TE. Low fidelity bypass of O(2)-(3-pyridyl)-4-oxobutylthymine, the most persistent bulky adduct produced by the tobacco specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by model DNA polymerases. Chem Res Toxicol. 2012 Jun 18; 25(6):1195-202. PMID: 22533615.
      View in: PubMed
    2. Lin JM, Prakasha Gowda AS, Sharma AK, Amin S. In vitro growth inhibition of human cancer cells by novel honokiol analogs. Bioorg Med Chem. 2012 May 15; 20(10):3202-11. PMID: 22533983; PMCID: PMC3345044.
    3. Krishnegowda G, Prakasha Gowda AS, Tagaram HR, Carroll KF, Irby RB, Sharma AK, Amin S. Synthesis and biological evaluation of a novel class of isatin analogs as dual inhibitors of tubulin polymerization and Akt pathway. Bioorg Med Chem. 2011 Oct 15; 19(20):6006-14. PMID: 21920762; PMCID: PMC3235409.
    4. Sk UH, Prakasha Gowda AS, Crampsie MA, Yun JK, Spratt TE, Amin S, Sharma AK. Development of novel naphthalimide derivatives and their evaluation as potential melanoma therapeutics. Eur J Med Chem. 2011 Aug; 46(8):3331-8. PMID: 21609852.
      View in: PubMed
    5. Krishnegowda G, Sharma AK, Krzeminski J, Gowda AS, Lin JM, Desai D, Spratt TE, Amin S. Facile syntheses of O(2)-[4-(3-pyridyl-4-oxobut-1-yl]thymidine, the major adduct formed by tobacco specific nitrosamine 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in vivo, and its site-specifically adducted oligodeoxynucleotides. Chem Res Toxicol. 2011 Jun 20; 24(6):960-7. PMID: 21524094; PMCID: PMC3118900.
    6. Rubinson EH, Gowda AS, Spratt TE, Gold B, Eichman BF. An unprecedented nucleic acid capture mechanism for excision of DNA damage. Nature. 2010 Nov 18; 468(7322):406-11. PMID: 20927102; PMCID: PMC4160814.
    7. Prakasha Gowda AS, Polizzi JM, Eckert KA, Spratt TE. Incorporation of gemcitabine and cytarabine into DNA by DNA polymerase beta and ligase III/XRCC1. Biochemistry. 2010 Jun 15; 49(23):4833-40. PMID: 20459144.
      View in: PubMed
    8. DeCarlo L, Gowda AS, Suo Z, Spratt TE. Formation of purine-purine mispairs by Sulfolobus solfataricus DNA polymerase IV. Biochemistry. 2008 Aug 05; 47(31):8157-64. PMID: 18616289; PMCID: PMC2570044.
    9. Gowda AS, Madhunapantula SV, Achur RN, Valiyaveettil M, Bhavanandan VP, Gowda DC. Structural basis for the adherence of Plasmodium falciparum-infected erythrocytes to chondroitin 4-sulfate and design of novel photoactivable reagents for the identification of parasite adhesive proteins. J Biol Chem. 2007 Jan 12; 282(2):916-28. PMID: 17085451.
      View in: PubMed
    10. Kesavulu MM, Prakasha Gowda AS, Ramya TN, Surolia N, Suguna K. Plasmepsin inhibitors: design, synthesis, inhibitory studies and crystal structure analysis. J Pept Res. 2005 Oct; 66(4):211-9. PMID: 16138859.
      View in: PubMed
    11. Abiraj K, Prasad HS, Gowda AS, Gowda DC. Design, synthesis and antibacterial activity studies of model peptidess of proline/arginine-rich region in bactenecin7. Protein Pept Lett. 2004 Aug; 11(4):291-300. PMID: 15468471.
      View in: PubMed
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