PSU Profiles
Last Name

Erika F.H. Saunders

TitleProfessor and Chair
InstitutionCollege of Medicine
Address500 University Drive, Hershey, PA 17033
Mailbox: H073
vCardDownload vCard

    Collapse Biography 
    Collapse awards and honors
    1998Howard Hughes Medical Scholar Fellowship
    2004American Psychiatric Association Research Colloquium for Junior Investigators, American Psychiatric Association
    2006University of Michigan Resident Writing Award, University of Michigan
    2010Penn State Resident Teaching Award, Penn State College of Medicine Department of Psychiatry
    2011Dean's Award for Excellence in Teaching, Penn State College of Medicine
    2011Career Development Institute for Bipolar Disorder, University of Pittsburgh, PA
    2012Fellow, American Psychiatric Association
    2012NCDEU New Investigator Award, American Society for Clinical Psychopharmacology
    2013Named in Best Doctors
    2015Eta Chapter of the Pennsylvania Alpha Omega Alpha Honor Medical Society, Penn State College of Medicine
    2015American College of Psychiatrists

    Collapse Overview 
    Collapse overview
    Current position:
    Shively-Tan Professor and Chair, Department of Psychiatry
    Penn State College of Medicine

    Our lab studies the link between clinical phenotype of bipolar disorder and biologic and genetic underpinnings of the disease. Bipolar disorder has a variable clinical presentation that likely reflects multiple biological and genetic etiologies. Through the study of biological factors that correlate with clinical phenotype and outcome, we aim to identify markers of illness that define a subgroup of patients who may have a homogeneous etiology of illness, and use those markers to predict and to follow treatment response. Focusing on a subpopulation of patients narrows the variability in etiology and treatment response and moves the field closer to applying principles of personalized medicine to patients suffering from bipolar disorder. Using the tools of translational research, we are currently studying the relationship between sleep phenotypes, mood outcome and inflammation, stress hormones and metabolites of polyunsaturated fatty acid pathways.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Krishnamurthy V, Mukherjee D, Reider A, Seaman S, Singh G, Fernandez-Mendoza J, Saunders E. Subjective and objective sleep discrepancy in symptomatic bipolar disorder compared to healthy controls. J Affect Disord. 2018 03 15; 229:247-253. PMID: 29329056.
      View in: PubMed
    2. McInnis MG, Assari S, Kamali M, Ryan K, Langenecker SA, Saunders EFH, Versha K, Evans S, O'Shea KS, Mower Provost E, Marshall D, Forger D, Deldin P, Zoellner S. Cohort Profile: The Heinz C. Prechter Longitudinal Study of Bipolar Disorder. Int J Epidemiol. 2017 Dec 02. PMID: 29211851.
      View in: PubMed
    3. Saunders EFH. Introduction. J Clin Psychiatry. 2017 Sep/Oct; 78(8):1148. PMID: 29099552.
      View in: PubMed
    4. Mukherjee D, Krishnamurthy VB, Millett CE, Reider A, Can A, Groer M, Fuchs D, Postolache TT, Saunders EFH. Total sleep time and kynurenine metabolism associated with mood symptom severity in bipolar disorder. Bipolar Disord. 2018 02; 20(1):27-34. PMID: 28833866.
      View in: PubMed
    5. Millett CE, Mukherjee D, Reider A, Can A, Groer M, Fuchs D, Postolache TT, Kelleher SL, Saunders EFH. Peripheral zinc and neopterin concentrations are associated with mood severity in bipolar disorder in a gender-specific manner. Psychiatry Res. 2017 Sep; 255:52-58. PMID: 28528241.
      View in: PubMed
    6. Saunders EF. Introduction. J Clin Psychiatry. 2017 Feb; 78(2):214. PMID: 28234435.
      View in: PubMed
    7. Heath J, Lehman E, Saunders EF, Craig T. Anxiety and depression in adults with primary immunodeficiency: How much do these patients experience and how much do they attribute to their primary immunodeficiency? Allergy Asthma Proc. 2016 Sep; 37(5):409-15. PMID: 27657526.
      View in: PubMed
    8. Saunders EF. Introduction. J Clin Psychiatry. 2016 May; 77(5):672. PMID: 27249076.
      View in: PubMed
    9. Ryan KA, Assari S, Pester BD, Hinrichs K, Angers K, Baker A, Marshall DF, Stringer D, Saunders EF, Kamali M, McInnis MG, Langenecker SA. Similar Trajectory of Executive Functioning Performance over 5 years among individuals with Bipolar Disorder and Unaffected Controls using Latent Growth Modeling. J Affect Disord. 2016 07 15; 199:87-94. PMID: 27093492.
      View in: PubMed
    10. Marshall DF, Passarotti AM, Ryan KA, Kamali M, Saunders EF, Pester B, McInnis MG, Langenecker SA. Deficient inhibitory control as an outcome of childhood trauma. Psychiatry Res. 2016 Jan 30; 235:7-12. PMID: 26707783.
      View in: PubMed
    11. Schwartz S, Schultz S, Reider A, Saunders EF. Daily mood monitoring of symptoms using smartphones in bipolar disorder: A pilot study assessing the feasibility of ecological momentary assessment. J Affect Disord. 2016 Feb; 191:88-93. PMID: 26655117; PMCID: PMC4799837 [Available on 02/01/17].
    12. Saunders EF, Reider A, Singh G, Gelenberg AJ, Rapoport SI. Low unesterified:esterified eicosapentaenoic acid (EPA) plasma concentration ratio is associated with bipolar disorder episodes, and omega-3 plasma concentrations are altered by treatment. Bipolar Disord. 2015 Nov; 17(7):729-42. PMID: 26424416; PMCID: PMC4623957 [Available on 11/01/16].
    13. Saunders EF. Early career psychiatrists. Introduction. J Clin Psychiatry. 2015 Oct; 76(10):1373. PMID: 26528643.
      View in: PubMed
    14. Saunders EF, Fernandez-Mendoza J, Kamali M, Assari S, McInnis MG. The effect of poor sleep quality on mood outcome differs between men and women: A longitudinal study of bipolar disorder. J Affect Disord. 2015 Jul 15; 180:90-6. PMID: 25885066; PMCID: PMC4448970.
    15. Saunders EF. Introduction. J Clin Psychiatry. 2015 Apr; 76(4):426. PMID: 25919833.
      View in: PubMed
    16. Saunders EF. JCP early career psychiatrists. Introduction. J Clin Psychiatry. 2014 Sep; 75(9):1009. PMID: 25295425.
      View in: PubMed
    17. Saunders EF, Nazir R, Kamali M, Ryan KA, Evans S, Langenecker S, Gelenberg AJ, McInnis MG. Gender differences, clinical correlates, and longitudinal outcome of bipolar disorder with comorbid migraine. J Clin Psychiatry. 2014 May; 75(5):512-9. PMID: 24816075; PMCID: PMC4211932.
    18. Saunders EF, Novick DM, Fernandez-Mendoza J, Kamali M, Ryan KA, Langenecker SA, Gelenberg AJ, McInnis MG. Sleep quality during euthymia in bipolar disorder: the role of clinical features, personality traits, and stressful life events. Int J Bipolar Disord. 2013; 1:16. PMID: 25505683; PMCID: PMC4230686.
    19. Aggarwal R, Baweja R, Saunders EF, Singareddy R. CPAP-induced mania in bipolar disorder: a case report. Bipolar Disord. 2013 Nov; 15(7):803-7. PMID: 23980584; PMCID: PMC4208920.
    20. Fouche AS, Saunders EF, Craig T. Depression and anxiety in patients with hereditary angioedema. Ann Allergy Asthma Immunol. 2014 Apr; 112(4):371-5. PMID: 24428960; PMCID: PMC4211935.
    21. Jen, A; Saunders, EFH; Ornstein, R; Kamali, M; McInnis, M. . Impulsivity, Alcohol Use Disorders and Anxiety Disorders associated with Eating Disorders in Bipolar Disorder. International Journal of Bipolar Disorders. 2013; 16(1).
    22. Marshall DF, Walker SJ, Ryan KA, Kamali M, Saunders EF, Weldon AL, Adams KM, McInnis MG, Langenecker SA. Greater executive and visual memory dysfunction in comorbid bipolar disorder and substance use disorder. Psychiatry Res. 2012 Dec 30; 200(2-3):252-7. PMID: 22769049; PMCID: PMC3650480.
    23. Saunders EF, Fitzgerald KD, Zhang P, McInnis MG. Clinical features of bipolar disorder comorbid with anxiety disorders differ between men and women. Depress Anxiety. 2012 Aug; 29(8):739-46. PMID: 22461133; PMCID: PMC3650482.
    24. Kamali M, Saunders EF, Prossin AR, Brucksch CB, Harrington GJ, Langenecker SA, McInnis MG. Associations between suicide attempts and elevated bedtime salivary cortisol levels in bipolar disorder. J Affect Disord. 2012 Feb; 136(3):350-8. PMID: 22154566; PMCID: PMC3683957.
    25. Vederman AC, Weisenbach SL, Rapport LJ, Leon HM, Haase BD, Franti LM, Schallmo MP, Saunders EF, Kamali MM, Zubieta JK, Langenecker SA, McInnis MG. Modality-specific alterations in the perception of emotional stimuli in Bipolar Disorder compared to Healthy Controls and Major Depressive Disorder. Cortex. 2012 Sep; 48(8):1027-34. PMID: 21683948; PMCID: PMC3660134.
    26. Saunders EF, Zhang P, Copeland JN, Mclnnis MG, Zöllner S. Suggestive linkage at 9p22 in bipolar disorder weighted by alcohol abuse. Am J Med Genet B Neuropsychiatr Genet. 2009 Dec 05; 150B(8):1133-8. PMID: 19259988.
      View in: PubMed
    27. Saunders BD, Saunders EF, Gauger PG. Lithium therapy and hyperparathyroidism: an evidence-based assessment. World J Surg. 2009 Nov; 33(11):2314-23. PMID: 19252941.
      View in: PubMed
    28. Saunders EF, Silk KR. Personality trait dimensions and the pharmacological treatment of borderline personality disorder. J Clin Psychopharmacol. 2009 Oct; 29(5):461-7. PMID: 19745646.
      View in: PubMed
    29. Langenecker SA, Saunders EF, Kade AM, Ransom MT, McInnis MG. Intermediate: cognitive phenotypes in bipolar disorder. J Affect Disord. 2010 May; 122(3):285-93. PMID: 19800130; PMCID: PMC3773480.
    30. McEachin RC, Keller BJ, Saunders EF, McInnis MG. Modeling gene-by-environment interaction in comorbid depression with alcohol use disorders via an integrated bioinformatics approach. BioData Min. 2008 Jul 17; 1(1):2. PMID: 18822146; PMCID: PMC2547861.
    31. Saunders EH, Scott LJ, McInnis MG, Burmeister M. Familiality and diagnostic patterns of subphenotypes in the National Institutes of Mental Health bipolar sample. Am J Med Genet B Neuropsychiatr Genet. 2008 Jan 05; 147B(1):18-26. PMID: 17525972.
      View in: PubMed
    32. Margolin DH, Saunders EH, Bronfin B, de Rosa N, Axthelm MK, Goloubeva OG, Eapen S, Gelman RS, Letvin NL. Germinal center function in the spleen during simian HIV infection in rhesus monkeys. J Immunol. 2006 Jul 15; 177(2):1108-19. PMID: 16818768.
      View in: PubMed
    33. Margolin DH, Saunders EF, Bronfin B, de Rosa N, Axthelm MK, Alvarez X, Letvin NL. High frequency of virus-specific B lymphocytes in germinal centers of simian-human immunodeficiency virus-infected rhesus monkeys. J Virol. 2002 Apr; 76(8):3965-73. PMID: 11907236; PMCID: PMC136115.
    34. Helmuth EF, Letvin NL, Margolin DH. Germline repertoire of the immunoglobulin V(H)3 family in rhesus monkeys. Immunogenetics. 2000 Jun; 51(7):519-27. PMID: 10912503.
      View in: PubMed
    Saunders's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    Co-Authors Expand Description
    Similar People Expand Description
    Same Department Expand Description
    Physical Neighbors Expand Description