PSU Profiles
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Last Name
Institution

Steven Schiff

TitleBrush Chair Professor of Engineering
InstitutionCollege of Engineering
DepartmentEngineering Science and Mechanics
AddressW311 Millennium Science Cmplx
University Park, PA 16802
Phone8148634210
Other Positions
TitleProfessor
InstitutionCollege of Medicine
DepartmentNeurosurgery

InstitutionHuck Institutes of the Life Sciences


 Overview 
 overview
PREFERRED TITLE/ROLE:

Director, Penn State Center for Neural Engineering
Brush Chair Professor of Engineering
Professor of Neurosurgery
Professor of Engineering Science and Mechanics

GRADUATE PROGRAM AFFILIATIONS:

Neuroscience

EDUCATION:

S.B., Massachusetts Institute of Technology, 1977
M.D., Duke University, 1980
Ph.D. (Physiology, G. Somjen), Duke University, 1985
General surgery internship, Duke University, 1981
Neurosurgery residency, Duke University, 1989
Pediatric neurosurgery fellowship, Children's Hospital of Philadelphia, 1990

NARRATIVE:

Dr. Schiff's research focuses on understanding the physics of dynamical disease of the nervous system, developing smart prosthetics to treat those diseases, and global health.


 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Wei Y, Ullah G, Schiff SJ. Unification of neuronal spikes, seizures, and spreading depression. J Neurosci. 2014 Aug 27; 34(35):11733-43.
    View in: PubMed
  2. Wei Y, Ullah G, Ingram J, Schiff SJ. Oxygen and seizure dynamics: II. Computational modeling. J Neurophysiol. 2014 Jul 15; 112(2):213-23.
    View in: PubMed
  3. Ingram J, Zhang C, Cressman JR, Hazra A, Wei Y, Koo YE, Ziburkus J, Kopelman R, Xu J, Schiff SJ. Oxygen and seizure dynamics: I. Experiments. J Neurophysiol. 2014 Jul 15; 112(2):205-12.
    View in: PubMed
  4. Sedigh-Sarvestani M, Thuku GI, Sunderam S, Parkar A, Weinstein SL, Schiff SJ, Gluckman BJ. Rapid eye movement sleep and hippocampal theta oscillations precede seizure onset in the tetanus toxin model of temporal lobe epilepsy. J Neurosci. 2014 Jan 22; 34(4):1105-14.
    View in: PubMed
  5. La Corte G, Wei Y, Chernyy N, Gluckman BJ, Schiff SJ. Frequency dependence of behavioral modulation by hippocampal electrical stimulation. J Neurophysiol. 2014 Feb; 111(3):470-80.
    View in: PubMed
  6. Kiwanuka J, Bazira J, Mwanga J, Tumusiime D, Nyesigire E, Lwanga N, Warf BC, Kapur V, Poss M, Schiff SJ. The microbial spectrum of neonatal sepsis in Uganda: recovery of culturable bacteria in mother-infant pairs. PLoS One. 2013; 8(8):e72775.
    View in: PubMed
  7. Gorzelic P, Schiff SJ, Sinha A. Model-based rational feedback controller design for closed-loop deep brain stimulation of Parkinson's disease. J Neural Eng. 2013 Apr; 10(2):026016.
    View in: PubMed
  8. Ingram JM, Zhang C, Xu J, Schiff SJ. FRET excited ratiometric oxygen sensing in living tissue. J Neurosci Methods. 2013 Mar 30; 214(1):45-51.
    View in: PubMed
  9. Žiburkus J, Cressman JR, Schiff SJ. Seizures as imbalanced up states: excitatory and inhibitory conductances during seizure-like events. J Neurophysiol. 2013 Mar; 109(5):1296-306.
    View in: PubMed
  10. Sedigh-Sarvestani M, Schiff SJ, Gluckman BJ. Reconstructing mammalian sleep dynamics with data assimilation. PLoS Comput Biol. 2012; 8(11):e1002788.
    View in: PubMed
  11. Berzhanskaya J, Chernyy N, Gluckman BJ, Schiff SJ, Ascoli GA. Modulation of hippocampal rhythms by subthreshold electric fields and network topology. J Comput Neurosci. 2013 Jun; 34(3):369-89.
    View in: PubMed
  12. Schiff SJ, Ranjeva SL, Sauer TD, Warf BC. Rainfall drives hydrocephalus in East Africa. J Neurosurg Pediatr. 2012 Sep; 10(3):161-7.
    View in: PubMed
  13. Xiao Y, Huang XY, Van Wert S, Barreto E, Wu JY, Gluckman BJ, Schiff SJ. The role of inhibition in oscillatory wave dynamics in the cortex. Eur J Neurosci. 2012 Jul; 36(2):2201-12.
    View in: PubMed
  14. Geronimo A, Schiff SJ, Kamrunnahar M. Visual evoked potentials for attentional gating in a brain-computer interface. Conf Proc IEEE Eng Med Biol Soc. 2012; 2012:1745-8.
    View in: PubMed
  15. Warf BC, Dagi AR, Kaaya BN, Schiff SJ. Five-year survival and outcome of treatment for postinfectious hydrocephalus in Ugandan infants. J Neurosurg Pediatr. 2011 Nov; 8(5):502-8.
    View in: PubMed
  16. Warf BC, Alkire BC, Bhai S, Hughes C, Schiff SJ, Vincent JR, Meara JG. Costs and benefits of neurosurgical intervention for infant hydrocephalus in sub-Saharan Africa. J Neurosurg Pediatr. 2011 Nov; 8(5):509-21.
    View in: PubMed
  17. Kamrunnahar M, Dias NS, Schiff SJ. Toward a model-based predictive controller design in brain-computer interfaces. Ann Biomed Eng. 2011 May; 39(5):1482-92.
    View in: PubMed
  18. Li L, Padhi A, Ranjeva SL, Donaldson SC, Warf BC, Mugamba J, Johnson D, Opio Z, Jayarao B, Kapur V, Poss M, Schiff SJ. Association of bacteria with hydrocephalus in Ugandan infants. J Neurosurg Pediatr. 2011 Jan; 7(1):73-87.
    View in: PubMed
  19. Kamrunnahar M, Schiff SJ. A square root ensemble Kalman filter application to a motor-imagery brain-computer interface. Conf Proc IEEE Eng Med Biol Soc. 2011; 2011:6385-8.
    View in: PubMed
  20. Mandell JG, Neuberger T, Drapaca CS, Webb AG, Schiff SJ. The dynamics of brain and cerebrospinal fluid growth in normal versus hydrocephalic mice. J Neurosurg Pediatr. 2010 Jul; 6(1):1-10.
    View in: PubMed
  21. Schiff SJ. Towards model-based control of Parkinson's disease. Philos Trans A Math Phys Eng Sci. 2010 May 13; 368(1918):2269-308.
    View in: PubMed
  22. Ullah G, Schiff SJ. Assimilating seizure dynamics. PLoS Comput Biol. 2010 May; 6(5):e1000776.
    View in: PubMed
  23. Dias NS, Kamrunnahar M, Mendes PM, Schiff SJ, Correia JH. Feature selection on movement imagery discrimination and attention detection. Med Biol Eng Comput. 2010 Apr; 48(4):331-41.
    View in: PubMed
  24. Schachter SC, Guttag J, Schiff SJ, Schomer DL. Advances in the application of technology to epilepsy: the CIMIT/NIO Epilepsy Innovation Summit. Epilepsy Behav. 2009 Sep; 16(1):3-46.
    View in: PubMed
  25. Sunderam S, Chernyy N, Peixoto N, Mason JP, Weinstein SL, Schiff SJ, Gluckman BJ. Seizure entrainment with polarizing low-frequency electric fields in a chronic animal epilepsy model. J Neural Eng. 2009 Aug; 6(4):046009.
    View in: PubMed
  26. Sauer TD, Schiff SJ. Data assimilation for heterogeneous networks: the consensus set. Phys Rev E Stat Nonlin Soft Matter Phys. 2009 May; 79(5 Pt 1):051909.
    View in: PubMed
  27. Ullah G, Schiff SJ. Tracking and control of neuronal Hodgkin-Huxley dynamics. Phys Rev E Stat Nonlin Soft Matter Phys. 2009 Apr; 79(4 Pt 1):040901.
    View in: PubMed
  28. Cressman JR, Ullah G, Ziburkus J, Schiff SJ, Barreto E. The influence of sodium and potassium dynamics on excitability, seizures, and the stability of persistent states: I. Single neuron dynamics. J Comput Neurosci. 2009 Apr; 26(2):159-70.
    View in: PubMed
  29. Kamrunnahar M, Dias NS, Schiff SJ. Optimization of electrode channels in Brain Computer Interfaces. Conf Proc IEEE Eng Med Biol Soc. 2009; 2009:6477-80.
    View in: PubMed
  30. Schiff SJ. Kalman meets neuron: the emerging intersection of control theory with neuroscience. Conf Proc IEEE Eng Med Biol Soc. 2009; 2009:3318-21.
    View in: PubMed
  31. Chernyy N, Schiff SJ, Gluckman BJ. Time dependence of stimulation/recording-artifact transfer function estimates for neural interface systems. Conf Proc IEEE Eng Med Biol Soc. 2009; 2009:1380-3.
    View in: PubMed
  32. Ullah G, Cressman JR, Barreto E, Schiff SJ. The influence of sodium and potassium dynamics on excitability, seizures, and the stability of persistent states. II. Network and glial dynamics. J Comput Neurosci. 2009 Apr; 26(2):171-83.
    View in: PubMed
  33. Kruglikov SY, Chari S, Rapp PE, Weinstein SL, Given BK, Schiff SJ. Fully optimized discrimination of physiological responses to auditory stimuli. J Neural Eng. 2008 Jun; 5(2):133-43.
    View in: PubMed
  34. Kamrunnahar M, Dias NS, Schiff SJ, Gluckman BJ. Model-based responses and features in Brain Computer Interfaces. Conf Proc IEEE Eng Med Biol Soc. 2008; 2008:4482-5.
    View in: PubMed
  35. Chernyy N, Schiff SJ, Gluckman BJ. Multi-taper transfer function estimation for stimulation artifact removal from neural recordings. Conf Proc IEEE Eng Med Biol Soc. 2008; 2008:2772-6.
    View in: PubMed
  36. Schiff SJ, Sauer T. Kalman filter control of a model of spatiotemporal cortical dynamics. J Neural Eng. 2008 Mar; 5(1):1-8.
    View in: PubMed
  37. Schiff SJ, Huang X, Wu JY. Dynamical evolution of spatiotemporal patterns in mammalian middle cortex. Phys Rev Lett. 2007 Apr 27; 98(17):178102.
    View in: PubMed
  38. Sunderam S, Chernyy N, Peixoto N, Mason JP, Weinstein SL, Schiff SJ, Gluckman BJ. Improved sleep-wake and behavior discrimination using MEMS accelerometers. J Neurosci Methods. 2007 Jul 30; 163(2):373-83.
    View in: PubMed
  39. Dias NS, Kamrunnahar M, Mendes PM, Schiff SJ, Correia JH. Comparison of EEG pattern classification methods for brain-computer interfaces. Conf Proc IEEE Eng Med Biol Soc. 2007; 2007:2540-3.
    View in: PubMed
  40. Ziburkus J, Cressman JR, Barreto E, Schiff SJ. Interneuron and pyramidal cell interplay during in vitro seizure-like events. J Neurophysiol. 2006 Jun; 95(6):3948-54.
    View in: PubMed
  41. Sunderam S, Chernyy N, Mason J, Peixoto N, Weinstein SL, Schiff SJ, Gluckman BJ. Seizure modulation with applied electric fields in chronically implanted animals. Conf Proc IEEE Eng Med Biol Soc. 2006; 1:1612-5.
    View in: PubMed
  42. Schiff SJ, Sauer T, Kumar R, Weinstein SL. Neuronal spatiotemporal pattern discrimination: the dynamical evolution of seizures. Neuroimage. 2005 Dec; 28(4):1043-55.
    View in: PubMed
  43. Park EH, Barreto E, Gluckman BJ, Schiff SJ, So P. A model of the effects of applied electric fields on neuronal synchronization. J Comput Neurosci. 2005 Aug; 19(1):53-70.
    View in: PubMed
  44. Richardson KA, Schiff SJ, Gluckman BJ. Control of traveling waves in the Mammalian cortex. Phys Rev Lett. 2005 Jan 21; 94(2):028103.
    View in: PubMed
  45. Jerger KK, Weinstein SL, Sauer T, Schiff SJ. Multivariate linear discrimination of seizures. Clin Neurophysiol. 2005 Mar; 116(3):545-51.
    View in: PubMed
  46. Schiff SJ. Dangerous phase. Neuroinformatics. 2005; 3(4):315-8.
    View in: PubMed
  47. Huang X, Troy WC, Yang Q, Ma H, Laing CR, Schiff SJ, Wu JY. Spiral waves in disinhibited mammalian neocortex. J Neurosci. 2004 Nov 3; 24(44):9897-902.
    View in: PubMed
  48. Netoff TI, Pecora LM, Schiff SJ. Analytical coupling detection in the presence of noise and nonlinearity. Phys Rev E Stat Nonlin Soft Matter Phys. 2004 Jan; 69(1 Pt 2):017201.
    View in: PubMed
  49. Kruglikov SY, Schiff SJ. Interplay of electroencephalogram phase and auditory-evoked neural activity. J Neurosci. 2003 Nov 5; 23(31):10122-7.
    View in: PubMed
  50. Francis JT, Gluckman BJ, Schiff SJ. Sensitivity of neurons to weak electric fields. J Neurosci. 2003 Aug 13; 23(19):7255-61.
    View in: PubMed
  51. Richardson KA, Gluckman BJ, Weinstein SL, Glosch CE, Moon JB, Gwinn RP, Gale K, Schiff SJ. In vivo modulation of hippocampal epileptiform activity with radial electric fields. Epilepsia. 2003 Jun; 44(6):768-77.
    View in: PubMed
  52. Netoff TI, Schiff SJ. Decreased neuronal synchronization during experimental seizures. J Neurosci. 2002 Aug 15; 22(16):7297-307.
    View in: PubMed
  53. Schiff SJ, Dunagan BK, Worth RM. Failure of single-unit neuronal activity to differentiate globus pallidus internus and externus in Parkinson disease. J Neurosurg. 2002 Jul; 97(1):119-28.
    View in: PubMed
  54. So P, Barreto E, Josic K, Sander E, Schiff SJ. Limits to the experimental detection of nonlinear synchrony. Phys Rev E Stat Nonlin Soft Matter Phys. 2002 Apr; 65(4 Pt 2A):046225.
    View in: PubMed
  55. Jerger KK, Netoff TI, Francis JT, Sauer T, Pecora L, Weinstein SL, Schiff SJ. Early seizure detection. J Clin Neurophysiol. 2001 May; 18(3):259-68.
    View in: PubMed
  56. Gluckman BJ, Nguyen H, Weinstein SL, Schiff SJ. Adaptive electric field control of epileptic seizures. J Neurosci. 2001 Jan 15; 21(2):590-600.
    View in: PubMed
  57. Kestle J, Drake J, Milner R, Sainte-Rose C, Cinalli G, Boop F, Piatt J, Haines S, Schiff S, Cochrane D, Steinbok P, MacNeil N. Long-term follow-up data from the Shunt Design Trial. Pediatr Neurosurg. 2000 Nov; 33(5):230-236.
    View in: PubMed
  58. Schiff SJ, Colella D, Jacyna GM, Hughes E, Creekmore JW, Marshall A, Bozek-Kuzmicki M, Benke G, Gaillard WD, Conry J, Weinstein SR. Brain chirps: spectrographic signatures of epileptic seizures. Clin Neurophysiol. 2000 Jun; 111(6):953-8.
    View in: PubMed
  59. Barreto E, So P, Gluckman BJ, Schiff SJ. From generalized synchrony to topological decoherence: emergent sets in coupled chaotic systems. Phys Rev Lett. 2000 Feb 21; 84(8):1689-92.
    View in: PubMed
  60. Schiff SJ. Forecasting brain storms. Nat Med. 1998 Oct; 4(10):1117-8.
    View in: PubMed
  61. Drake JM, Kestle JR, Milner R, Cinalli G, Boop F, Piatt J, Haines S, Schiff SJ, Cochrane DD, Steinbok P, MacNeil N. Randomized trial of cerebrospinal fluid shunt valve design in pediatric hydrocephalus. Neurosurgery. 1998 Aug; 43(2):294-303; discussion 303-5.
    View in: PubMed
  62. So P, Francis JT, Netoff TI, Gluckman BJ, Schiff SJ. Periodic orbits: a new language for neuronal dynamics. Biophys J. 1998 Jun; 74(6):2776-85.
    View in: PubMed
  63. Hertz-Pannier L, Gaillard WD, Mott SH, Cuenod CA, Bookheimer SY, Weinstein S, Conry J, Papero PH, Schiff SJ, Le Bihan D, Theodore WH. Noninvasive assessment of language dominance in children and adolescents with functional MRI: a preliminary study. Neurology. 1997 Apr; 48(4):1003-12.
    View in: PubMed
  64. Gluckman BJ, Neel EJ, Netoff TI, Ditto WL, Spano ML, Schiff SJ. Electric field suppression of epileptiform activity in hippocampal slices. J Neurophysiol. 1996 Dec; 76(6):4202-5.
    View in: PubMed
  65. Heyes MP, Saito K, Milstien S, Schiff SJ. Quinolinic acid in tumors, hemorrhage and bacterial infections of the central nervous system in children. J Neurol Sci. 1995 Nov; 133(1-2):112-8.
    View in: PubMed
  66. Scott DA, Schiff SJ. Predictability of EEG interictal spikes. Biophys J. 1995 Nov; 69(5):1748-57.
    View in: PubMed
  67. Aitken PG, Sauer T, Schiff SJ. Looking for chaos in brain slices. J Neurosci Methods. 1995 Jun; 59(1):41-8.
    View in: PubMed
  68. Jerger K, Schiff SJ. Periodic pacing an in vitro epileptic focus. J Neurophysiol. 1995 Feb; 73(2):876-9.
    View in: PubMed
  69. Gaillard WD, White S, Malow B, Flamini R, Weinstein S, Sato S, Kufta C, Schiff S, Devinsky O, Fazilat S, et al. FDG-PET in children and adolescents with partial seizures: role in epilepsy surgery evaluation. Epilepsy Res. 1995 Jan; 20(1):77-84.
    View in: PubMed
  70. Schiff SJ, Aldroubi A, Unser M, Sato S. Fast wavelet transformation of EEG. Electroencephalogr Clin Neurophysiol. 1994 Dec; 91(6):442-55.
    View in: PubMed
  71. Rivera AD, Burke T, Schiff SJ, Weiss IP. An experimental study of reflex variability in selective dorsal rhizotomy. J Neurosurg. 1994 Dec; 81(6):885-94.
    View in: PubMed
  72. Kast J, Duong D, Nowzari F, Chadduck WM, Schiff SJ. Time-related patterns of ventricular shunt failure. Childs Nerv Syst. 1994 Nov; 10(8):524-8.
    View in: PubMed
  73. Gossard JP, Floeter MK, Kawai Y, Burke RE, Chang T, Schiff SJ. Fluctuations of excitability in the monosynaptic reflex pathway to lumbar motoneurons in the cat. J Neurophysiol. 1994 Sep; 72(3):1227-39.
    View in: PubMed
  74. Schiff SJ, Jerger K, Duong DH, Chang T, Spano ML, Ditto WL. Controlling chaos in the brain. Nature. 1994 Aug 25; 370(6491):615-20.
    View in: PubMed
  75. Schiff SJ, Jerger K, Chang T, Sauer T, Aitken PG. Stochastic versus deterministic variability in simple neuronal circuits: II. Hippocampal slice. Biophys J. 1994 Aug; 67(2):684-91.
    View in: PubMed
  76. Chang T, Schiff SJ, Sauer T, Gossard JP, Burke RE. Stochastic versus deterministic variability in simple neuronal circuits: I. Monosynaptic spinal cord reflexes. Biophys J. 1994 Aug; 67(2):671-83.
    View in: PubMed
  77. Schiff SJ, Sauer T, Chang T. Discriminating deterministic versus stochastic dynamics in neuronal activity. Integr Physiol Behav Sci. 1994 Jul-Sep; 29(3):246-61.
    View in: PubMed
  78. Packer RJ, Sutton LN, Patel KM, Duhaime AC, Schiff S, Weinstein SR, Gaillard WD, Conry JA, Schut L. Seizure control following tumor surgery for childhood cortical low-grade gliomas. J Neurosurg. 1994 Jun; 80(6):998-1003.
    View in: PubMed
  79. Schiff SJ, Weinstein SL. Use of recombinant human erythropoietin to avoid blood transfusion in a Jehovah's Witness requiring hemispherectomy. Case report. J Neurosurg. 1993 Oct; 79(4):600-2.
    View in: PubMed
  80. Weiss IP, Schiff SJ. Reflex variability in selective dorsal rhizotomy. J Neurosurg. 1993 Sep; 79(3):346-53.
    View in: PubMed
  81. Schiff SJ, Chang T. Differentiation of linearly correlated noise from chaos in a biologic system using surrogate data. Biol Cybern. 1992; 67(5):387-93.
    View in: PubMed
  82. Schiff SJ. A surgeon's risk of AIDS. J Neurosurg. 1990 Nov; 73(5):651-60.
    View in: PubMed
  83. Aitken PG, Schiff SJ. Barbiturate protection against hypoxic neuronal damage in vitro. J Neurosurg. 1986 Aug; 65(2):230-2.
    View in: PubMed
  84. Schiff SJ, Somjen GG. Hyperexcitability following moderate hypoxia in hippocampal tissue slices. Brain Res. 1985 Jul 1; 337(2):337-40.
    View in: PubMed
  85. Moore JW, Stockbridge N, Schiff SJ. On the squid axon membrane's response to sequential voltage and current clamps. Biophys J. 1982 Dec; 40(3):259-62.
    View in: PubMed
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