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Richard Legro

TitleProfessor
InstitutionCollege of Medicine
DepartmentObstetrics and Gynecology
Address500 University Drive Hershey PA 17033
Phone7175318478

 Overview 
 overview
PREFERRED TITLE/ROLE:

Physician, Professor of Obstetrics and Gynecology and Public Health Sciences
Co-Leader, Participant and Clinical Interactive Resources (PCIR), Penn State Clinical and Translational Institute

GRADUATE PROGRAM AFFILIATIONS:

Cellular and Molecular Physiology

EDUCATION:

M.D., Medical/Clinical Mount Sinai School of Medicine, 1987
Internship and Residency, Magee-Womens Hospital, University of Pittsburgh, Obstetrics and Gynecology, 1987-1991
Fellowship, University of Southern California, Women's Hospital, Reproductive Endocrinology, 1991-1993




 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Legro RS, Adashi EY. Introduction: Germline stem cell therapy in humans: two are not enough. Fertil Steril. 2014 Jan; 101(1):1-2.
    View in: PubMed
  2. Legro RS, Arslanian SA, Ehrmann DA, Hoeger KM, Murad MH, Pasquali R, Welt CK. Diagnosis and treatment of polycystic ovary syndrome: an endocrine society clinical practice guideline. J Clin Endocrinol Metab. 2013 Dec; 98(12):4565-92.
    View in: PubMed
  3. Legro RS, Brzyski RG, Diamond MP, Coutifaris C, Schlaff WD, Alvero R, Casson P, Christman GM, Huang H, Yan Q, Haisenleder DJ, Barnhart KT, Bates GW, Usadi R, Lucidi R, Baker V, Trussell JC, Krawetz SA, Snyder P, Ohl D, Santoro N, Eisenberg E, Zhang H. The Pregnancy in Polycystic Ovary Syndrome II study: baseline characteristics and effects of obesity from a multicenter randomized clinical trial. Fertil Steril. 2014 Jan; 101(1):258-269.e8.
    View in: PubMed
  4. Legro RS. Introduction to the guest editor: Marcelle Cedars, MD. Semin Reprod Med. 2013 Nov; 31(6):389.
    View in: PubMed
  5. Kuang H, Li Y, Wu X, Hou L, Wu T, Liu J, Ng EH, Stener-Victorin E, Legro RS, Zhang H. Acupuncture and clomiphene citrate for live birth in polycystic ovary syndrome: study design of a randomized controlled trial. Evid Based Complement Alternat Med. 2013; 2013:527303.
    View in: PubMed
  6. Dmitrovic R, Kunselman AR, Legro RS. Sildenafil citrate in the treatment of pain in primary dysmenorrhea: a randomized controlled trial. Hum Reprod. 2013 Nov; 28(11):2958-65.
    View in: PubMed
  7. Legro RS. Introduction: back to the future: origins of polycystic ovary syndrome. Fertil Steril. 2013 Jul; 100(1):1.
    View in: PubMed
  8. Perales-Puchalt A, Legro RS. Ovulation induction in women with polycystic ovary syndrome. Steroids. 2013 Aug; 78(8):767-72.
    View in: PubMed
  9. Legro RS. The quality of ovulation is strained in normal women. Hum Reprod. 2013 Jun; 28(6):1446-7.
    View in: PubMed
  10. Raja-Khan N, Urbanek M, Rodgers RJ, Legro RS. The Role of TGF-ß in Polycystic Ovary Syndrome. Reprod Sci. 2014 Jan; 21(1):20-31.
    View in: PubMed
  11. Pauli JM, Lloyd T, Kunselman AR, Stetter CM, Dodson WC, Legro RS. Effect of adolescent pregnancy on final adult height in non-Hispanic white women. Arch Gynecol Obstet. 2013 Sep; 288(3):679-82.
    View in: PubMed
  12. Bates GW, Legro RS. Longterm management of Polycystic Ovarian Syndrome (PCOS). Mol Cell Endocrinol. 2013 Jul 5; 373(1-2):91-7.
    View in: PubMed
  13. Sasidevi A, Vellanki P, Kunselman AR, Raja-Khan N, Dunaif A, Legro RS. Familial aggregation of circulating C-reactive protein in polycystic ovary syndrome. Hum Reprod. 2013 Mar; 28(3):770-6.
    View in: PubMed
  14. Usadi RS, Legro RS. Reproductive impact of polycystic ovary syndrome. Curr Opin Endocrinol Diabetes Obes. 2012 Dec; 19(6):505-11.
    View in: PubMed
  15. Wickenheisser JK, Biegler JM, Nelson-Degrave VL, Legro RS, Strauss JF, McAllister JM. Cholesterol side-chain cleavage gene expression in theca cells: augmented transcriptional regulation and mRNA stability in polycystic ovary syndrome. PLoS One. 2012; 7(11):e48963.
    View in: PubMed
  16. Mutharasan P, Galdones E, Peñalver Bernabé B, Garcia OA, Jafari N, Shea LD, Woodruff TK, Legro RS, Dunaif A, Urbanek M. Evidence for chromosome 2p16.3 polycystic ovary syndrome susceptibility locus in affected women of European ancestry. J Clin Endocrinol Metab. 2013 Jan; 98(1):E185-90.
    View in: PubMed
  17. Legro RS. Quo vadis randomized controlled trials in infertility? Fertil Steril. 2012 Dec; 98(6):1350-1.
    View in: PubMed
  18. Legro RS. Obesity and PCOS: implications for diagnosis and treatment. Semin Reprod Med. 2012 Dec; 30(6):496-506.
    View in: PubMed
  19. Legro RS, Dodson WC, Gnatuk CL, Estes SJ, Kunselman AR, Meadows JW, Kesner JS, Krieg EF, Rogers AM, Haluck RS, Cooney RN. Effects of gastric bypass surgery on female reproductive function. J Clin Endocrinol Metab. 2012 Dec; 97(12):4540-8.
    View in: PubMed
  20. Legro RS, Niederberger C, Pellicer A. Disclosure of duplicative studies: damned if you don't. Fertil Steril. 2012 Dec; 98(6):1347-9.
    View in: PubMed
  21. Legro RS. Turner syndrome: new insights into an old disorder. Fertil Steril. 2012 Oct; 98(4):773-4.
    View in: PubMed
  22. Coney P, Demers LM, Dodson WC, Kunselman AR, Ladson G, Legro RS. Determination of vitamin D in relation to body mass index and race in a defined population of black and white women. Int J Gynaecol Obstet. 2012 Oct; 119(1):21-5.
    View in: PubMed
  23. Jones MR, Chazenbalk G, Xu N, Chua AK, Eigler T, Mengesha E, Chen YH, Lee JM, Pall M, Li X, Chen YD, Taylor KD, Mathur R, Krauss RM, Rotter JI, Legro RS, Azziz R, Goodarzi MO. Steroidogenic regulatory factor FOS is underexpressed in polycystic ovary syndrome (PCOS) adipose tissue and genetically associated with PCOS susceptibility. J Clin Endocrinol Metab. 2012 Sep; 97(9):E1750-7.
    View in: PubMed
  24. Witchel SF, Recabarren SE, González F, Diamanti-Kandarakis E, Cheang KI, Duleba AJ, Legro RS, Homburg R, Pasquali R, Lobo RA, Zouboulis CC, Kelestimur F, Fruzzetti F, Futterweit W, Norman RJ, Abbott DH. Emerging concepts about prenatal genesis, aberrant metabolism and treatment paradigms in polycystic ovary syndrome. Endocrine. 2012 Dec; 42(3):526-34.
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  25. Dmitrovic R, Kunselman AR, Legro RS. Continuous compared with cyclic oral contraceptives for the treatment of primary dysmenorrhea: a randomized controlled trial. Obstet Gynecol. 2012 Jun; 119(6):1143-50.
    View in: PubMed
  26. Roth LW, Huang H, Legro RS, Diamond MP, Coutifaris C, Carson SA, Steinkampf MP, Carr BR, McGovern PG, Cataldo NA, Gosman GG, Nestler JE, Myers ER, Zhang H, Schlaff WD. Altering hirsutism through ovulation induction in women with polycystic ovary syndrome. Obstet Gynecol. 2012 Jun; 119(6):1151-6.
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  27. Diamond MP, Kruger M, Santoro N, Zhang H, Casson P, Schlaff W, Coutifaris C, Brzyski R, Christman G, Carr BR, McGovern PG, Cataldo NA, Steinkampf MP, Gosman GG, Nestler JE, Carson S, Myers EE, Eisenberg E, Legro RS. Endometrial shedding effect on conception and live birth in women with polycystic ovary syndrome. Obstet Gynecol. 2012 May; 119(5):902-8.
    View in: PubMed
  28. Legro RS, Kunselman AR. A good meta-analysis is hard to find. Fertil Steril. 2012 May; 97(5):1048-9.
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  29. Legro RS. Superovulation and multiple birth: in search of kryptonite. Fertil Steril. 2012 Apr; 97(4):793-4.
    View in: PubMed
  30. Polotsky AJ, Allshouse A, Crawford SL, Harlow SD, Khalil N, Santoro N, Legro RS. Relative contributions of oligomenorrhea and hyperandrogenemia to the risk of metabolic syndrome in midlife women. J Clin Endocrinol Metab. 2012 Jun; 97(6):E868-77.
    View in: PubMed
  31. Legro RS, Kunselman AR, Brzyski RG, Casson PR, Diamond MP, Schlaff WD, Christman GM, Coutifaris C, Taylor HS, Eisenberg E, Santoro N, Zhang H. The Pregnancy in Polycystic Ovary Syndrome II (PPCOS II) trial: rationale and design of a double-blind randomized trial of clomiphene citrate and letrozole for the treatment of infertility in women with polycystic ovary syndrome. Contemp Clin Trials. 2012 May; 33(3):470-81.
    View in: PubMed
  32. Leach RE, Jessmon P, Coutifaris C, Kruger M, Myers ER, Ali-Fehmi R, Carson SA, Legro RS, Schlaff WD, Carr BR, Steinkampf MP, Silva S, Leppert PC, Giudice L, Diamond MP, Armant DR. High throughput, cell type-specific analysis of key proteins in human endometrial biopsies of women from fertile and infertile couples. Hum Reprod. 2012 Mar; 27(3):814-28.
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  33. Goodarzi MO, Jones MR, Li X, Chua AK, Garcia OA, Chen YD, Krauss RM, Rotter JI, Ankener W, Legro RS, Azziz R, Strauss JF, Dunaif A, Urbanek M. Replication of association of DENND1A and THADA variants with polycystic ovary syndrome in European cohorts. J Med Genet. 2012 Feb; 49(2):90-5.
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  34. Hill LD, Ewens KG, Maher BS, York TP, Legro RS, Dunaif A, Strauss JF. Catechol-O-methyltransferase (COMT) single nucleotide polymorphisms and haplotypes are not major risk factors for polycystic ovary syndrome. Mol Cell Endocrinol. 2012 Mar 5; 350(1):72-7.
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  35. Jones MR, Chua AK, Mengesha EA, Taylor KD, Chen YD, Li X, Krauss RM, Rotter JI. Metabolic and cardiovascular genes in polycystic ovary syndrome: a candidate-wide association study (CWAS). Steroids. 2012 Mar 10; 77(4):317-22.
    View in: PubMed
  36. Booker CJ, Dodson WC, Kunselman AR, Repke JT, Legro RS. Twenty-four-hour ambulatory blood pressure monitor heart rate: a potential marker for gestational hypertension in at-risk women. Am J Perinatol. 2012 May; 29(5):339-46.
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  37. Fauser BC, Tarlatzis BC, Rebar RW, Legro RS, Balen AH, Lobo R, Carmina E, Chang J, Yildiz BO, Laven JS, Boivin J, Petraglia F, Wijeyeratne CN, Norman RJ, Dunaif A, Franks S, Wild RA, Dumesic D, Barnhart K. Consensus on women's health aspects of polycystic ovary syndrome (PCOS): the Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group. Fertil Steril. 2012 Jan; 97(1):28-38.e25.
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  38. Aubuchon M, Legro RS. Polycystic ovary syndrome: current infertility management. Clin Obstet Gynecol. 2011 Dec; 54(4):675-84.
    View in: PubMed
  39. Trussell JC, Christman GM, Ohl DA, Legro RS, Krawetz SA, Snyder PJ, Patrizio P, Polotsky AJ, Diamond MP, Casson PR, Coutifaris C, Barnhart K, Brzyski RG, Schlaff WD, Meacham R, Shin D, Thomas T, Zhang M, Santoro N, Eisenberg E, Zhang H. Recruitment challenges of a multicenter randomized controlled varicocelectomy trial. Fertil Steril. 2011 Dec; 96(6):1299-305.
    View in: PubMed
  40. Pauli JM, Raja-Khan N, Wu X, Legro RS. Current perspectives of insulin resistance and polycystic ovary syndrome. Diabet Med. 2011 Dec; 28(12):1445-54.
    View in: PubMed
  41. Legro RS. Barriers to conducting clinical research in reproductive medicine: United States of America. Fertil Steril. 2011 Oct; 96(4):817-9.
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  42. Casson PR, Krawetz SA, Diamond MP, Zhang H, Legro RS, Schlaff WD, Coutifaris C, Brzyski RG, Christman GM, Santoro N, Eisenberg E. Proactively establishing a biologic specimens repository for large clinical trials: an idea whose time has come. Syst Biol Reprod Med. 2011 Oct; 57(5):217-21.
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  43. Dmitrovic R, Katcher HI, Kunselman AR, Legro RS. Continuous glucose monitoring during pregnancy in women with polycystic ovary syndrome. Obstet Gynecol. 2011 Oct; 118(4):878-85.
    View in: PubMed
  44. Krawetz SA, Casson PR, Diamond MP, Zhang H, Legro RS, Schlaff WD, Coutifaris C, Brzyski RG, Christman GM, Santoro N, Eisenberg E. Establishing a biologic specimens repository for reproductive clinical trials: technical aspects. Syst Biol Reprod Med. 2011 Oct; 57(5):222-7.
    View in: PubMed
  45. Aubuchon M, Kunselman AR, Schlaff WD, Diamond MP, Coutifaris C, Carson SA, Steinkampf MP, Carr BR, McGovern PG, Cataldo NA, Gosman GG, Nestler JE, Myers ER, Legro RS. Metformin and/or clomiphene do not adversely affect liver or renal function in women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2011 Oct; 96(10):E1645-9.
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  46. Diamond MP, Mitwally M, Casper R, Ager J, Legro RS, Brzyski R, Casson P, Eisenberg E, Zhang H. Estimating rates of multiple gestation pregnancies: sample size calculation from the assessment of multiple intrauterine gestations from ovarian stimulation (AMIGOS) trial. Contemp Clin Trials. 2011 Nov; 32(6):902-8.
    View in: PubMed
  47. Ladson G, Dodson WC, Sweet SD, Archibong AE, Kunselman AR, Demers LM, Williams NI, Coney P, Legro RS. Racial influence on the polycystic ovary syndrome phenotype: a black and white case-control study. Fertil Steril. 2011 Jul; 96(1):224-229.e2.
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  48. Ladson G, Dodson WC, Sweet SD, Archibong AE, Kunselman AR, Demers LM, Lee PA, Williams NI, Coney P, Legro RS. Effects of metformin in adolescents with polycystic ovary syndrome undertaking lifestyle therapy: a pilot randomized double-blind study. Fertil Steril. 2011 Jun 30; 95(8):2595-8.e1-6.
    View in: PubMed
  49. Schlaff WD, Zhang H, Diamond MP, Coutifaris C, Casson PR, Brzyski RG, Christman GM, Barnhart KT, Trussell JC, Krawetz SA, Snyder PJ, Ohl D, Santoro N, Eisenberg E, Huang H, Legro RS. Increasing burden of institutional review in multicenter clinical trials of infertility: the Reproductive Medicine Network experience with the Pregnancy in Polycystic Ovary Syndrome (PPCOS) I and II studies. Fertil Steril. 2011 Jul; 96(1):15-8.
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  50. Legro RS. Metformin as adjuvant therapy to IVF in women with PCOS: when is intention-to-treat unintentional? Hum Reprod. 2011 Aug; 26(8):2043-4.
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  51. Jones MR, Chua A, Chen YD, Li X, Krauss RM, Rotter JI, Legro RS, Azziz R, Goodarzi MO. Harnessing expression data to identify novel candidate genes in polycystic ovary syndrome. PLoS One. 2011; 6(5):e20120.
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  52. Taylor MC, Reema Kar A, Kunselman AR, Stetter CM, Dunaif A, Legro RS. Evidence for increased cardiovascular events in the fathers but not mothers of women with polycystic ovary syndrome. Hum Reprod. 2011 Aug; 26(8):2226-31.
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  53. Raja-Khan N, Stener-Victorin E, Wu X, Legro RS. The physiological basis of complementary and alternative medicines for polycystic ovary syndrome. Am J Physiol Endocrinol Metab. 2011 Jul; 301(1):E1-E10.
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  54. Pasquali R, Stener-Victorin E, Yildiz BO, Duleba AJ, Hoeger K, Mason H, Homburg R, Hickey T, Franks S, Tapanainen JS, Balen A, Abbott DH, Diamanti-Kandarakis E, Legro RS. PCOS Forum: research in polycystic ovary syndrome today and tomorrow. Clin Endocrinol (Oxf). 2011 Apr; 74(4):424-33.
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  55. Ewens KG, Jones MR, Ankener W, Stewart DR, Urbanek M, Dunaif A, Legro RS, Chua A, Azziz R, Spielman RS, Goodarzi MO, Strauss JF. Type 2 diabetes susceptibility single-nucleotide polymorphisms are not associated with polycystic ovary syndrome. Fertil Steril. 2011 Jun 30; 95(8):2538-41.e1-6.
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  56. Dapuzzo L, Seitz FE, Dodson WC, Stetter C, Kunselman AR, Legro RS. Incomplete and inconsistent reporting of maternal and fetal outcomes in infertility treatment trials. Fertil Steril. 2011 Jun 30; 95(8):2527-30.
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  57. Wickham EP, Ewens KG, Legro RS, Dunaif A, Nestler JE, Strauss JF. Polymorphisms in the SHBG gene influence serum SHBG levels in women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2011 Apr; 96(4):E719-27.
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  58. Ewens KG, Jones MR, Ankener W, Stewart DR, Urbanek M, Dunaif A, Legro RS, Chua A, Azziz R, Spielman RS, Goodarzi MO, Strauss JF. FTO and MC4R gene variants are associated with obesity in polycystic ovary syndrome. PLoS One. 2011; 6(1):e16390.
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  59. Ladson G, Dodson WC, Sweet SD, Archibong AE, Kunselman AR, Demers LM, Williams NI, Coney P, Legro RS. The effects of metformin with lifestyle therapy in polycystic ovary syndrome: a randomized double-blind study. Fertil Steril. 2011 Mar 1; 95(3):1059-66.e1-7.
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  60. Raja-Khan N, Kunselman AR, Hogeman CS, Stetter CM, Demers LM, Legro RS. Effects of atorvastatin on vascular function, inflammation, and androgens in women with polycystic ovary syndrome: a double-blind, randomized, placebo-controlled trial. Fertil Steril. 2011 Apr; 95(5):1849-52.
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  61. Legro RS. Metformin during pregnancy in polycystic ovary syndrome: another vitamin bites the dust. J Clin Endocrinol Metab. 2010 Dec; 95(12):5199-202.
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  62. Raja-Khan N, Shuja SA, Kunselman AR, Hogeman CS, Demers LM, Gnatuk CL, Legro RS. Brachial artery conductance during reactive hyperemia is increased in women with polycystic ovary syndrome. Eur J Obstet Gynecol Reprod Biol. 2011 Mar; 155(1):49-53.
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  63. Legro RS, Schlaff WD, Diamond MP, Coutifaris C, Casson PR, Brzyski RG, Christman GM, Trussell JC, Krawetz SA, Snyder PJ, Ohl D, Carson SA, Steinkampf MP, Carr BR, McGovern PG, Cataldo NA, Gosman GG, Nestler JE, Myers ER, Santoro N, Eisenberg E, Zhang M, Zhang H. Total testosterone assays in women with polycystic ovary syndrome: precision and correlation with hirsutism. J Clin Endocrinol Metab. 2010 Dec; 95(12):5305-13.
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  64. Zhang H, Legro RS, Zhang J, Zhang L, Chen X, Huang H, Casson PR, Schlaff WD, Diamond MP, Krawetz SA, Coutifaris C, Brzyski RG, Christman GM, Santoro N, Eisenberg E. Decision trees for identifying predictors of treatment effectiveness in clinical trials and its application to ovulation in a study of women with polycystic ovary syndrome. Hum Reprod. 2010 Oct; 25(10):2612-21.
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  65. Raja-Khan N, Kunselman AR, Demers LM, Ewens KG, Spielman RS, Legro RS. A variant in the fibrillin-3 gene is associated with TGF-ß and inhibin B levels in women with polycystic ovary syndrome. Fertil Steril. 2010 Dec; 94(7):2916-9.
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  66. Williams NI, Reed JL, Leidy HJ, Legro RS, De Souza MJ. Estrogen and progesterone exposure is reduced in response to energy deficiency in women aged 25-40 years. Hum Reprod. 2010 Sep; 25(9):2328-39.
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  67. Legro RS, Sauer MV, Mottla GL, Richter KS, Li X, Dodson WC, Liao D. Effect of air quality on assisted human reproduction. Hum Reprod. 2010 May; 25(5):1317-24.
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  68. Ewens KG, Stewart DR, Ankener W, Urbanek M, McAllister JM, Chen C, Baig KM, Parker SC, Margulies EH, Legro RS, Dunaif A, Strauss JF, Spielman RS. Family-based analysis of candidate genes for polycystic ovary syndrome. J Clin Endocrinol Metab. 2010 May; 95(5):2306-15.
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  69. Legro RS, Roller RL, Dodson WC, Stetter CM, Kunselman AR, Dunaif A. Associations of birthweight and gestational age with reproductive and metabolic phenotypes in women with polycystic ovarian syndrome and their first-degree relatives. J Clin Endocrinol Metab. 2010 Feb; 95(2):789-99.
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  70. Coviello AD, Sam S, Legro RS, Dunaif A. High prevalence of metabolic syndrome in first-degree male relatives of women with polycystic ovary syndrome is related to high rates of obesity. J Clin Endocrinol Metab. 2009 Nov; 94(11):4361-6.
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  71. Legro RS. Insulin resistance in women's health: why it matters and how to identify it. Curr Opin Obstet Gynecol. 2009 Aug; 21(4):301-5.
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  72. Devlin MJ, Stetter CM, Lin HM, Beck TJ, Legro RS, Petit MA, Lieberman DE, Lloyd T. Peripubertal estrogen levels and physical activity affect femur geometry in young adult women. Osteoporos Int. 2010 Apr; 21(4):609-17.
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  73. Pagidas K, Carson SA, McGovern PG, Barnhart HX, Myers ER, Legro RS, Diamond MP, Carr BR, Schlaff WD, Coutifaris C, Steinkampf MP, Cataldo NA, Nestler JE, Gosman G, Giudice LC. Body mass index and intercourse compliance. Fertil Steril. 2010 Sep; 94(4):1447-50.
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  74. Pagidas K, Carson SA, McGovern PG, Barnhart HX, Myers ER, Legro RS, Diamond MP, Carr BR, Schlaff WD, Coutifaris C, Steinkampf MP, Cataldo NA, Nestler JE, Gosman G, Giudice LC. Intercourse compliance, ovulation, and treatment success in the National Institute of Child Health and Human Development-Reproductive Medicine Network's Pregnancy in Polycystic Ovary Syndrome (PPCOS) Trial. Fertil Steril. 2010 Sep; 94(4):1444-6.
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  75. Rausch ME, Legro RS, Barnhart HX, Schlaff WD, Carr BR, Diamond MP, Carson SA, Steinkampf MP, McGovern PG, Cataldo NA, Gosman GG, Nestler JE, Giudice LC, Leppert PC, Myers ER, Coutifaris C. Predictors of pregnancy in women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2009 Sep; 94(9):3458-66.
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  76. Chen C, Wickenheisser J, Ewens KG, Ankener W, Legro RS, Dunaif A, McAllister JM, Spielman RS, Strauss JF. PDE8A genetic variation, polycystic ovary syndrome and androgen levels in women. Mol Hum Reprod. 2009 Aug; 15(8):459-69.
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  77. Urbanek M, Nampiaparampil G, D'Souza J, Sefton E, Ackerman C, Legro RS, Dunaif A. The role of genetic variation in the lamin a/c gene in the etiology of polycystic ovary syndrome. J Clin Endocrinol Metab. 2009 Jul; 94(7):2665-9.
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  78. Biyasheva A, Legro RS, Dunaif A, Urbanek M. Evidence for association between polycystic ovary syndrome (PCOS) and TCF7L2 and glucose intolerance in women with PCOS and TCF7L2. J Clin Endocrinol Metab. 2009 Jul; 94(7):2617-25.
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  79. Legro RS, McAllister JM. Heirarchical clustering and beyond in PCOS endometrium: brave new world. J Clin Endocrinol Metab. 2009 Apr; 94(4):1084-5.
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  80. Trussell JC, Kunselman AR, Legro RS. Epinephrine is associated with both erectile dysfunction and lower urinary tract symptoms. Fertil Steril. 2010 Feb; 93(3):837-42.
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  81. Legro RS. Impact of metformin, oral contraceptives, and lifestyle modification on polycystic ovary syndrome in obese adolescent women: do we need a new drug? J Clin Endocrinol Metab. 2008 Nov; 93(11):4218-20.
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  82. Azziz R, Carmina E, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale HF, Futterweit W, Janssen OE, Legro RS, Norman RJ, Taylor AE, Witchel SF. The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report. Fertil Steril. 2009 Feb; 91(2):456-88.
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  83. Legro RS. Individualizing infertility therapy with pharmacogenomics: vanity or vanguard? Pharmacogenomics. 2008 Sep; 9(9):1179-81.
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  84. Cataldo NA, Barnhart HX, Legro RS, Myers ER, Schlaff WD, Carr BR, Diamond MP, Carson SA, Steinkampf MP, Coutifaris C, McGovern PG, Gosman G, Nestler JE, Giudice LC. Extended-release metformin does not reduce the clomiphene citrate dose required to induce ovulation in polycystic ovary syndrome. J Clin Endocrinol Metab. 2008 Aug; 93(8):3124-7.
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  85. Sam S, Coviello AD, Sung YA, Legro RS, Dunaif A. Metabolic phenotype in the brothers of women with polycystic ovary syndrome. Diabetes Care. 2008 Jun; 31(6):1237-41.
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  86. Katcher HI, Kunselman AR, Dmitrovic R, Demers LM, Gnatuk CL, Kris-Etherton PM, Legro RS. Comparison of hormonal and metabolic markers after a high-fat, Western meal versus a low-fat, high-fiber meal in women with polycystic ovary syndrome. Fertil Steril. 2009 Apr; 91(4):1175-82.
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  87. Pauli EM, Legro RS, Demers LM, Kunselman AR, Dodson WC, Lee PA. Diminished paternity and gonadal function with increasing obesity in men. Fertil Steril. 2008 Aug; 90(2):346-51.
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  88. Kent SC, Gnatuk CL, Kunselman AR, Demers LM, Lee PA, Legro RS. Hyperandrogenism and hyperinsulinism in children of women with polycystic ovary syndrome: a controlled study. J Clin Endocrinol Metab. 2008 May; 93(5):1662-9.
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  89. Legro RS. New directions in polycystic ovary syndrome. Semin Reprod Med. 2008 Jan; 26(1):3-4.
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  90. Coney P, Ladson G, Sweet S, Legro RS. Does polycystic ovary syndrome increase the disparity in metabolic syndrome and cardiovascular-related health for African-American women? Semin Reprod Med. 2008 Jan; 26(1):35-8.
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  91. Sam S, Sung YA, Legro RS, Dunaif A. Evidence for pancreatic beta-cell dysfunction in brothers of women with polycystic ovary syndrome. Metabolism. 2008 Jan; 57(1):84-9.
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  92. Katcher HI, Legro RS, Kunselman AR, Gillies PJ, Demers LM, Bagshaw DM, Kris-Etherton PM. The effects of a whole grain-enriched hypocaloric diet on cardiovascular disease risk factors in men and women with metabolic syndrome. Am J Clin Nutr. 2008 Jan; 87(1):79-90.
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  93. McGovern PG, Carson SA, Barnhart HX, Myers ER, Legro RS, Diamond MP, Carr BR, Schlaff WD, Coutifaris C, Cataldo NA, Steinkampf MP, Nestler JE, Gosman G, Leppert PC, Giudice LC. Medication adherence and treatment success in the National Institute of Child Health and Human Development-Reproductive Medicine Network's Pregnancy in Polycystic Ovary Syndrome Trial. Fertil Steril. 2008 Oct; 90(4):1283-6.
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  94. Legro RS, Pauli JG, Kunselman AR, Meadows JW, Kesner JS, Zaino RJ, Demers LM, Gnatuk CL, Dodson WC. Effects of continuous versus cyclical oral contraception: a randomized controlled trial. J Clin Endocrinol Metab. 2008 Feb; 93(2):420-9.
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  95. Sweet S, Legro RS, Coney P. A comparison of methods and results in recruiting white and black women into reproductive studies: the MMC-PSU cooperative center on reproduction experience. Contemp Clin Trials. 2008 Jul; 29(4):478-81.
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  96. Legro RS, Barnhart HX, Schlaff WD, Carr BR, Diamond MP, Carson SA, Steinkampf MP, Coutifaris C, McGovern PG, Cataldo NA, Gosman GG, Nestler JE, Giudice LC, Ewens KG, Spielman RS, Leppert PC, Myers ER. Ovulatory response to treatment of polycystic ovary syndrome is associated with a polymorphism in the STK11 gene. J Clin Endocrinol Metab. 2008 Mar; 93(3):792-800.
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  97. Urbanek M, Sam S, Legro RS, Dunaif A. Identification of a polycystic ovary syndrome susceptibility variant in fibrillin-3 and association with a metabolic phenotype. J Clin Endocrinol Metab. 2007 Nov; 92(11):4191-8.
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  98. Norman RJ, Dewailly D, Legro RS, Hickey TE. Polycystic ovary syndrome. Lancet. 2007 Aug 25; 370(9588):685-97.
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  99. Leppert PC, Legro RS, Kjerulff KH. Hysterectomy and loss of fertility: implications for women's mental health. J Psychosom Res. 2007 Sep; 63(3):269-74.
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  100. Trussell JC, Legro RS. Erectile dysfunction: does insulin resistance play a part? Fertil Steril. 2007 Oct; 88(4):771-8.
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  101. Legro RS, Zaino RJ, Demers LM, Kunselman AR, Gnatuk CL, Williams NI, Dodson WC. The effects of metformin and rosiglitazone, alone and in combination, on the ovary and endometrium in polycystic ovary syndrome. Am J Obstet Gynecol. 2007 Apr; 196(4):402.e1-10; discussion 402.e10-1.
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  102. Legro RS. Pregnancy considerations in women with polycystic ovary syndrome. Clin Obstet Gynecol. 2007 Mar; 50(1):295-304.
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  103. Legro RS, Barnhart HX, Schlaff WD, Carr BR, Diamond MP, Carson SA, Steinkampf MP, Coutifaris C, McGovern PG, Cataldo NA, Gosman GG, Nestler JE, Giudice LC, Leppert PC, Myers ER. Clomiphene, metformin, or both for infertility in the polycystic ovary syndrome. N Engl J Med. 2007 Feb 8; 356(6):551-66.
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  104. Legro RS. A 27-year-old woman with a diagnosis of polycystic ovary syndrome. JAMA. 2007 Feb 7; 297(5):509-19.
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  105. McGovern PG, Legro RS, Myers ER, Barnhart HX, Carson SA, Diamond MP, Carr BR, Schlaff WD, Coutifaris C, Steinkampf MP, Nestler JE, Gosman G, Leppert PC, Giudice LC. Utility of screening for other causes of infertility in women with "known" polycystic ovary syndrome. Fertil Steril. 2007 Feb; 87(2):442-4.
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  106. Legro RS, Myers ER, Barnhart HX, Carson SA, Diamond MP, Carr BR, Schlaff WD, Coutifaris C, McGovern PG, Cataldo NA, Steinkampf MP, Nestler JE, Gosman G, Guidice LC, Leppert PC. The Pregnancy in Polycystic Ovary Syndrome study: baseline characteristics of the randomized cohort including racial effects. Fertil Steril. 2006 Oct; 86(4):914-33.
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  107. Azziz R, Carmina E, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale HF, Futterweit W, Janssen OE, Legro RS, Norman RJ, Taylor AE, Witchel SF. Positions statement: criteria for defining polycystic ovary syndrome as a predominantly hyperandrogenic syndrome: an Androgen Excess Society guideline. J Clin Endocrinol Metab. 2006 Nov; 91(11):4237-45.
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  108. Vgontzas AN, Trakada G, Bixler EO, Lin HM, Pejovic S, Zoumakis E, Chrousos GP, Legro RS. Plasma interleukin 6 levels are elevated in polycystic ovary syndrome independently of obesity or sleep apnea. Metabolism. 2006 Aug; 55(8):1076-82.
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  109. Diamanti-Kandarakis E, Kandarakis H, Legro RS. The role of genes and environment in the etiology of PCOS. Endocrine. 2006 Aug; 30(1):19-26.
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  110. Stewart DR, Dombroski BA, Urbanek M, Ankener W, Ewens KG, Wood JR, Legro RS, Strauss JF, Dunaif A, Spielman RS. Fine mapping of genetic susceptibility to polycystic ovary syndrome on chromosome 19p13.2 and tests for regulatory activity. J Clin Endocrinol Metab. 2006 Oct; 91(10):4112-7.
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  111. Legro RS. Type 2 diabetes and polycystic ovary syndrome. Fertil Steril. 2006 Jul; 86 Suppl 1:S16-7.
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  112. Dodson WC, Kunselman AR, Legro RS. Association of obesity with treatment outcomes in ovulatory infertile women undergoing superovulation and intrauterine insemination. Fertil Steril. 2006 Sep; 86(3):642-6.
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  113. Gosman GG, Katcher HI, Legro RS. Obesity and the role of gut and adipose hormones in female reproduction. Hum Reprod Update. 2006 Sep-Oct; 12(5):585-601.
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  114. Legro RS, Azziz R, Giudice L. A twenty-first century research agenda for polycystic ovary syndrome. Best Pract Res Clin Endocrinol Metab. 2006 Jun; 20(2):331-6.
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  115. Hickey TE, Legro RS, Norman RJ. Epigenetic modification of the X chromosome influences susceptibility to polycystic ovary syndrome. J Clin Endocrinol Metab. 2006 Jul; 91(7):2789-91.
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  116. Sam S, Legro RS, Essah PA, Apridonidze T, Dunaif A. Evidence for metabolic and reproductive phenotypes in mothers of women with polycystic ovary syndrome. Proc Natl Acad Sci U S A. 2006 May 2; 103(18):7030-5.
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  117. Legro RS. Long-term, low-dose flutamide does not cause hepatotoxicity in hyperandrogenic women. Nat Clin Pract Endocrinol Metab. 2006 Apr; 2(4):188-9.
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  118. Coviello AD, Legro RS, Dunaif A. Adolescent girls with polycystic ovary syndrome have an increased risk of the metabolic syndrome associated with increasing androgen levels independent of obesity and insulin resistance. J Clin Endocrinol Metab. 2006 Feb; 91(2):492-7.
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  119. Ehrmann DA, Liljenquist DR, Kasza K, Azziz R, Legro RS, Ghazzi MN. Prevalence and predictors of the metabolic syndrome in women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2006 Jan; 91(1):48-53.
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  120. Ho CK, Wood JR, Stewart DR, Ewens K, Ankener W, Wickenheisser J, Nelson-Degrave V, Zhang Z, Legro RS, Dunaif A, McAllister JM, Spielman R, Strauss JF. Increased transcription and increased messenger ribonucleic acid (mRNA) stability contribute to increased GATA6 mRNA abundance in polycystic ovary syndrome theca cells. J Clin Endocrinol Metab. 2005 Dec; 90(12):6596-602.
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  121. Urbanek M, Woodroffe A, Ewens KG, Diamanti-Kandarakis E, Legro RS, Strauss JF, Dunaif A, Spielman RS. Candidate gene region for polycystic ovary syndrome on chromosome 19p13.2. J Clin Endocrinol Metab. 2005 Dec; 90(12):6623-9.
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  122. Myers ER, Silva SG, Hafley G, Kunselman AR, Nestler JE, Legro RS. Estimating live birth rates after ovulation induction in polycystic ovary syndrome: sample size calculations for the pregnancy in polycystic ovary syndrome trial. Contemp Clin Trials. 2005 Jun; 26(3):271-80.
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  123. Wickenheisser JK, Nelson-DeGrave VL, Hendricks KL, Legro RS, Strauss JF, McAllister JM. Retinoids and retinol differentially regulate steroid biosynthesis in ovarian theca cells isolated from normal cycling women and women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2005 Aug; 90(8):4858-65.
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  124. Sam S, Legro RS, Bentley-Lewis R, Dunaif A. Dyslipidemia and metabolic syndrome in the sisters of women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2005 Aug; 90(8):4797-802.
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  125. Legro RS, Gnatuk CL, Kunselman AR, Dunaif A. Changes in glucose tolerance over time in women with polycystic ovary syndrome: a controlled study. J Clin Endocrinol Metab. 2005 Jun; 90(6):3236-42.
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  126. Legro RS, Chiu P, Kunselman AR, Bentley CM, Dodson WC, Dunaif A. Polycystic ovaries are common in women with hyperandrogenic chronic anovulation but do not predict metabolic or reproductive phenotype. J Clin Endocrinol Metab. 2005 May; 90(5):2571-9.
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  127. McGovern PG, Myers ER, Silva S, Coutifaris C, Carson SA, Legro RS, Schlaff WD, Carr BR, Steinkampf MP, Giudice LC, Leppert PC, Diamond MP. Absence of secretory endometrium after false-positive home urine luteinizing hormone testing. Fertil Steril. 2004 Nov; 82(5):1273-7.
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  128. Coutifaris C, Myers ER, Guzick DS, Diamond MP, Carson SA, Legro RS, McGovern PG, Schlaff WD, Carr BR, Steinkampf MP, Silva S, Vogel DL, Leppert PC. Histological dating of timed endometrial biopsy tissue is not related to fertility status. Fertil Steril. 2004 Nov; 82(5):1264-72.
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  129. Nelson-Degrave VL, Wickenheisser JK, Hendricks KL, Asano T, Fujishiro M, Legro RS, Kimball SR, Strauss JF, McAllister JM. Alterations in mitogen-activated protein kinase kinase and extracellular regulated kinase signaling in theca cells contribute to excessive androgen production in polycystic ovary syndrome. Mol Endocrinol. 2005 Feb; 19(2):379-90.
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  130. Ehrmann DA, Kasza K, Azziz R, Legro RS, Ghazzi MN. Effects of race and family history of type 2 diabetes on metabolic status of women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2005 Jan; 90(1):66-71.
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  131. Petit MA, Beck TJ, Lin HM, Bentley C, Legro RS, Lloyd T. Femoral bone structural geometry adapts to mechanical loading and is influenced by sex steroids: the Penn State Young Women's Health Study. Bone. 2004 Sep; 35(3):750-9.
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  132. Legro RS, Myers E. Surrogate end-points or primary outcomes in clinical trials in women with polycystic ovary syndrome? Hum Reprod. 2004 Aug; 19(8):1697-704.
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  133. Stamets K, Taylor DS, Kunselman A, Demers LM, Pelkman CL, Legro RS. A randomized trial of the effects of two types of short-term hypocaloric diets on weight loss in women with polycystic ovary syndrome. Fertil Steril. 2004 Mar; 81(3):630-7.
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  134. Legro RS, Castracane VD, Kauffman RP. Detecting insulin resistance in polycystic ovary syndrome: purposes and pitfalls. Obstet Gynecol Surv. 2004 Feb; 59(2):141-54.
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  135. Legro RS, Azziz R, Ehrmann D, Fereshetian AG, O'Keefe M, Ghazzi MN. Minimal response of circulating lipids in women with polycystic ovary syndrome to improvement in insulin sensitivity with troglitazone. J Clin Endocrinol Metab. 2003 Nov; 88(11):5137-44.
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  136. Carmina E, Legro RS, Stamets K, Lowell J, Lobo RA. Difference in body weight between American and Italian women with polycystic ovary syndrome: influence of the diet. Hum Reprod. 2003 Nov; 18(11):2289-93.
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  137. Nelson-DeGrave VL, Wickenheisser JK, Cockrell JE, Wood JR, Legro RS, Strauss JF, McAllister JM. Valproate potentiates androgen biosynthesis in human ovarian theca cells. Endocrinology. 2004 Feb; 145(2):799-808.
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  138. Legro RS. Diagnostic criteria in polycystic ovary syndrome. Semin Reprod Med. 2003 Aug; 21(3):267-75.
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  139. Legro RS. Polycystic ovary syndrome and cardiovascular disease: a premature association? Endocr Rev. 2003 Jun; 24(3):302-12.
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  140. Azziz R, Ehrmann DA, Legro RS, Fereshetian AG, O'Keefe M, Ghazzi MN. Troglitazone decreases adrenal androgen levels in women with polycystic ovary syndrome. Fertil Steril. 2003 Apr; 79(4):932-7.
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  141. Urbanek M, Du Y, Silander K, Collins FS, Steppan CM, Strauss JF, Dunaif A, Spielman RS, Legro RS. Variation in resistin gene promoter not associated with polycystic ovary syndrome. Diabetes. 2003 Jan; 52(1):214-7.
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  142. Legro RS, Lin HM, Demers LM, Lloyd T. Urinary free cortisol increases in adolescent caucasian females during perimenarche. J Clin Endocrinol Metab. 2003 Jan; 88(1):215-9.
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  143. Legro RS. Detection of insulin resistance and its treatment in adolescents with polycystic ovary syndrome. J Pediatr Endocrinol Metab. 2002 Dec; 15 Suppl 5:1367-78.
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  144. Legro RS, Strauss JF. Molecular progress in infertility: polycystic ovary syndrome. Fertil Steril. 2002 Sep; 78(3):569-76.
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  145. Lloyd T, Lin HM, Matthews AE, Bentley CM, Legro RS. Oral contraceptive use by teenage women does not affect body composition. Obstet Gynecol. 2002 Aug; 100(2):235-9.
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  146. Legro RS, Urbanek M, Kunselman AR, Leiby BE, Dunaif A. Self-selected women with polycystic ovary syndrome are reproductively and metabolically abnormal and undertreated. Fertil Steril. 2002 Jul; 78(1):51-7.
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  147. Legro RS, Bentley-Lewis R, Driscoll D, Wang SC, Dunaif A. Insulin resistance in the sisters of women with polycystic ovary syndrome: association with hyperandrogenemia rather than menstrual irregularity. J Clin Endocrinol Metab. 2002 May; 87(5):2128-33.
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  148. Legro RS, Kunselman AR, Demers L, Wang SC, Bentley-Lewis R, Dunaif A. Elevated dehydroepiandrosterone sulfate levels as the reproductive phenotype in the brothers of women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2002 May; 87(5):2134-8.
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  149. Legro RS. Polycystic ovary syndrome. Long term sequelae and management. Minerva Ginecol. 2002 Apr; 54(2):97-114.
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  150. Palmert MR, Gordon CM, Kartashov AI, Legro RS, Emans SJ, Dunaif A. Screening for abnormal glucose tolerance in adolescents with polycystic ovary syndrome. J Clin Endocrinol Metab. 2002 Mar; 87(3):1017-23.
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  151. Kent SC, Legro RS. Polycystic ovary syndrome in adolescents. Adolesc Med. 2002 Feb; 13(1):73-88, vi.
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  152. Lloyd T, Lin HM, Eggli DF, Dodson WC, Demers LM, Legro RS. Adolescent Caucasian mothers have reduced adult hip bone density. Fertil Steril. 2002 Jan; 77(1):136-40.
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  153. Nelson VL, Qin KN, Rosenfield RL, Wood JR, Penning TM, Legro RS, Strauss JF, McAllister JM. The biochemical basis for increased testosterone production in theca cells propagated from patients with polycystic ovary syndrome. J Clin Endocrinol Metab. 2001 Dec; 86(12):5925-33.
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  154. Legro RS, Kunselman AR, Dunaif A. Prevalence and predictors of dyslipidemia in women with polycystic ovary syndrome. Am J Med. 2001 Dec 1; 111(8):607-13.
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  155. Legro RS. Polycystic ovary syndrome: the new millenium. Mol Cell Endocrinol. 2001 Nov 26; 184(1-2):87-93.
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  156. Azziz R, Ehrmann D, Legro RS, Whitcomb RW, Hanley R, Fereshetian AG, O'Keefe M, Ghazzi MN. Troglitazone improves ovulation and hirsutism in the polycystic ovary syndrome: a multicenter, double blind, placebo-controlled trial. J Clin Endocrinol Metab. 2001 Apr; 86(4):1626-32.
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  157. Legro RS. Diabetes prevalence and risk factors in polycystic ovary syndrome. Obstet Gynecol Clin North Am. 2001 Mar; 28(1):99-109.
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  158. Bennett RA, Dodson WC, Olt GJ, Ahearn J, Legro RS. Spontaneous conception in the presence of stage IIIC endometrioid ovarian cancer. Fertil Steril. 2001 Mar; 75(3):623-4.
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  159. Legro RS, Kunselman AR, Miller SA, Satyaswaroop PG. Role of androgens in the growth of endometrial carcinoma: an in vivo animal model. Am J Obstet Gynecol. 2001 Feb; 184(3):303-8.
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  160. Vgontzas AN, Legro RS, Bixler EO, Grayev A, Kales A, Chrousos GP. Polycystic ovary syndrome is associated with obstructive sleep apnea and daytime sleepiness: role of insulin resistance. J Clin Endocrinol Metab. 2001 Feb; 86(2):517-20.
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  161. Urbanek M, Wu X, Vickery KR, Kao LC, Christenson LK, Schneyer A, Legro RS, Driscoll DA, Strauss JF, Dunaif A, Spielman RS. Allelic variants of the follistatin gene in polycystic ovary syndrome. J Clin Endocrinol Metab. 2000 Dec; 85(12):4455-61.
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  162. Lloyd T, Taylor DS, Lin HM, Matthews AE, Eggli DF, Legro RS. Oral contraceptive use by teenage women does not affect peak bone mass: a longitudinal study. Fertil Steril. 2000 Oct; 74(4):734-8.
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  163. Wickenheisser JK, Quinn PG, Nelson VL, Legro RS, Strauss JF, McAllister JM. Differential activity of the cytochrome P450 17alpha-hydroxylase and steroidogenic acute regulatory protein gene promoters in normal and polycystic ovary syndrome theca cells. J Clin Endocrinol Metab. 2000 Jun; 85(6):2304-11.
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  164. Coulson CC, Kunselman AR, Cain J, Legro RS. The mentor effect in student evaluation. Obstet Gynecol. 2000 Apr; 95(4):619-22.
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  165. Legro RS, Lin HM, Demers LM, Lloyd T. Rapid maturation of the reproductive axis during perimenarche independent of body composition. J Clin Endocrinol Metab. 2000 Mar; 85(3):1021-5.
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  166. Legro RS. Is there a male phenotype in polycystic ovary syndrome families? J Pediatr Endocrinol Metab. 2000; 13 Suppl 5:1307-9.
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  167. Urbanek M, Legro RS, Driscoll D, Strauss JF, Dunaif A, Spielman RS. Searching for the polycystic ovary syndrome genes. J Pediatr Endocrinol Metab. 2000; 13 Suppl 5:1311-3.
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  168. Legro RS. The genetics of obesity. Lessons for polycystic ovary syndrome. Ann N Y Acad Sci. 2000; 900:193-202.
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  169. Legro RS, Blanche P, Krauss RM, Lobo RA. Alterations in low-density lipoprotein and high-density lipoprotein subclasses among Hispanic women with polycystic ovary syndrome: influence of insulin and genetic factors. Fertil Steril. 1999 Dec; 72(6):990-5.
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  170. Cohen MA, Chang PL, Uhler M, Legro R, Sauer MV, Lindheim SR. Reproductive outcome after sterilization reversal in women of advanced reproductive age. J Assist Reprod Genet. 1999 Sep; 16(8):402-4.
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  171. Urbanek M, Legro RS, Driscoll DA, Azziz R, Ehrmann DA, Norman RJ, Strauss JF, Spielman RS, Dunaif A. Thirty-seven candidate genes for polycystic ovary syndrome: strongest evidence for linkage is with follistatin. Proc Natl Acad Sci U S A. 1999 Jul 20; 96(15):8573-8.
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  172. Good C, Tulchinsky M, Mauger D, Demers LM, Legro RS. Bone mineral density and body composition in lean women with polycystic ovary syndrome. Fertil Steril. 1999 Jul; 72(1):21-5.
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  173. Legro RS. Polycystic ovary syndrome. Phenotype to genotype. Endocrinol Metab Clin North Am. 1999 Jun; 28(2):379-96.
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  174. Nelson VL, Legro RS, Strauss JF, McAllister JM. Augmented androgen production is a stable steroidogenic phenotype of propagated theca cells from polycystic ovaries. Mol Endocrinol. 1999 Jun; 13(6):946-57.
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  175. Comings DE, Blake H, Dietz G, Gade-Andavolu R, Legro RS, Saucier G, Johnson P, Verde R, MacMurray JP. The proenkephalin gene (PENK) and opioid dependence. Neuroreport. 1999 Apr 6; 10(5):1133-5.
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  176. Legro RS, Gnatuk CL, Kunselman AR, Cain J. Oocyte donors as gynecologic teaching associates. Obstet Gynecol. 1999 Jan; 93(1):147-50.
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  177. Legro RS, Kunselman AR, Dodson WC, Dunaif A. Prevalence and predictors of risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: a prospective, controlled study in 254 affected women. J Clin Endocrinol Metab. 1999 Jan; 84(1):165-9.
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  178. Legro RS, Driscoll D, Strauss JF, Fox J, Dunaif A. Evidence for a genetic basis for hyperandrogenemia in polycystic ovary syndrome. Proc Natl Acad Sci U S A. 1998 Dec 8; 95(25):14956-60.
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  179. Legro RS. Polycystic ovary syndrome: current and future treatment paradigms. Am J Obstet Gynecol. 1998 Dec; 179(6 Pt 2):S101-S108.
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  180. Legro RS. Insulin resistance in polycystic ovary syndrome: treating a phenotype without a genotype. Mol Cell Endocrinol. 1998 Oct 25; 145(1-2):103-10.
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  181. Dodson WC, Moessner J, Miller J, Legro RS, Gnatuk CL. A randomized comparison of the methods of sperm preparation for intrauterine insemination. Fertil Steril. 1998 Sep; 70(3):574-5.
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  182. Legro RS, Finegood D, Dunaif A. A fasting glucose to insulin ratio is a useful measure of insulin sensitivity in women with polycystic ovary syndrome. J Clin Endocrinol Metab. 1998 Aug; 83(8):2694-8.
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  183. Legro RS, Spielman R, Urbanek M, Driscoll D, Strauss JF, Dunaif A. Phenotype and genotype in polycystic ovary syndrome. Recent Prog Horm Res. 1998; 53:217-56.
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  184. Legro RS, Shackleford DP, Moessner JM, Gnatuk CL, Dodson WC. ART in women 40 and over. Is the cost worth it? J Reprod Med. 1997 Feb; 42(2):76-82.
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  185. Wong IL, Legro RS, Lindheim SR, Paulson RJ, Sauer MV. Efficacy of oocytes donated by older women in an oocyte donation programme. Hum Reprod. 1996 Apr; 11(4):820-3.
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  186. Legro RS, Paulson RJ, Lobo RA, Sauer MV. Association of early beta-human chorionic gonadotrophin values with pregnancy wastage and multiple implantation in a donor oocyte programme. Hum Reprod. 1995 Dec; 10(12):3293-6.
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  187. Duffy DM, Legro RS, Chang L, Stanczyk FZ, Lobo RA. Metabolism of dihydrotestosterone to 5 alpha-androstane-3 alpha, 17 beta-diol glucuronide is greater in the peripheral compartment than in the splanchnic compartment. Fertil Steril. 1995 Oct; 64(4):736-9.
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  188. Legro RS, Laifer SA. First-trimester pancreatitis. Maternal and neonatal outcome. J Reprod Med. 1995 Oct; 40(10):689-95.
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  189. Legro RS, Price FV, Caritis SN. Successful conservative treatment of placenta percreta. Am J Obstet Gynecol. 1995 May; 172(5):1648-9.
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  190. Legro RS, Muhleman DR, Comings DE, Lobo RA, Kovacs BW. A dopamine D3 receptor genotype is associated with hyperandrogenic chronic anovulation and resistant to ovulation induction with clomiphene citrate in female Hispanics. Fertil Steril. 1995 Apr; 63(4):779-84.
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  191. Legro RS, Wong IL, Paulson RJ, Lobo RA, Sauer MV. Multiple implantation after oocyte donation: a frequent but inefficient event. Fertil Steril. 1995 Apr; 63(4):849-53.
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  192. Morris RS, Paulson RJ, Lindheim SR, Legro RS, Lobo RA, Sauer MV. Angiotensin-converting enzyme inhibition reverses luteal phase steroid production in oocyte donors. Fertil Steril. 1995 Apr; 63(4):854-8.
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  193. Lindheim SR, Legro RS, Morris RS, Vijod MA, Lobo RA, Paulson RJ, Sauer MV. Altered responses to stress in women undergoing in-vitro fertilization and recipients of oocyte donation. Hum Reprod. 1995 Feb; 10(2):320-3.
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  194. Legro RS. The genetics of polycystic ovary syndrome. Am J Med. 1995 Jan 16; 98(1A):9S-16S.
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  195. Legro RS, Wong IL, Paulson RJ, Lobo RA, Sauer MV. Recipient's age does not adversely affect pregnancy outcome after oocyte donation. Am J Obstet Gynecol. 1995 Jan; 172(1 Pt 1):96-100.
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  196. Legro RS, Carmina E, Stanczyk FZ, Gentzschein E, Lobo RA. Alterations in androgen conjugate levels in women and men with alopecia. Fertil Steril. 1994 Oct; 62(4):744-50.
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  197. Legro RS, Dietz GW, Comings DE, Lobo RA, Kovacs BW. Association of dopamine D2 receptor gene haplotypes with anovulation and fecundity in female Hispanics. Hum Reprod. 1994 Jul; 9(7):1271-5.
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  198. Legro RS, Price FV, Hill LM, Caritis SN. Nonsurgical management of placenta percreta: a case report. Obstet Gynecol. 1994 May; 83(5 Pt 2):847-9.
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  199. Legro RS, Shahbahrami B, Lobo RA, Kovacs BW. Size polymorphisms of the androgen receptor among female Hispanics and correlation with androgenic characteristics. Obstet Gynecol. 1994 May; 83(5 Pt 1):701-6.
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  200. Lindheim SR, Legro RS, Morris RS, Wong IL, Tran DQ, Vijod MA, Stanczyk FZ, Lobo RA. The effect of progestins on behavioral stress responses in postmenopausal women. J Soc Gynecol Investig. 1994 Jan-Mar; 1(1):79-83.
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  201. Legro RS, Ary BA, Paulson RJ, Stanczyk FZ, Sauer MV. Premature luteinization as detected by elevated serum progesterone is associated with a higher pregnancy rate in donor oocyte in-vitro fertilization. Hum Reprod. 1993 Sep; 8(9):1506-11.
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  202. Comings DE, Muhleman D, Dietz G, Dino M, LeGro R, Gade R. Association between Tourette's syndrome and homozygosity at the dopamine D3 receptor gene. Lancet. 1993 Apr 3; 341(8849):906.
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  203. Lindheim SR, Legro RS, Bernstein L, Stanczyk FZ, Vijod MA, Presser SC, Lobo RA. Behavioral stress responses in premenopausal and postmenopausal women and the effects of estrogen. Am J Obstet Gynecol. 1992 Dec; 167(6):1831-6.
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  204. Price FV, Legro RS, Watt-Morse M, Kaplan SS. Chediak-Higashi syndrome in pregnancy. Obstet Gynecol. 1992 May; 79(5 ( Pt 2)):804-6.
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Legro's Networks
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Concepts
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Co-Authors
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Similar People
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Same Department
Physical Neighbors
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