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Nancy Olsen

TitleProfessor Of Medicine, Chief Of Rheumatology
InstitutionCollege of Medicine
DepartmentMedicine
Address500 University Drive Hershey PA 17033
Phone7175315384

 Overview 
 overview
PREFERRED TITLE/ROLE:

Physician, Professor of Medicine, Chief of Rheumatology

EDUCATION:

Fellowship, Rheumatology, University of Texas Southwestern Medical Center (Dallas) (1983)
Residency, Internal Medicine, Medical College of Virginia/Virginia Commonwealth University (Richmond) (1980)
M.D., University of Chicago-Pritzker School of Medicine (Illinois) (1977)


 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Han BK, Kuzin I, Gaughan JP, Olsen NJ, Bottaro A. Baseline CXCL10 and CXCL13 levels are predictive biomarkers for tumor necrosis factor inhibitor therapy in patients with moderate to severe rheumatoid arthritis: a pilot, prospective study. Arthritis Res Ther. 2015; 18(1):93.
    View in: PubMed
  2. Raj P, Rai E, Song R, Khan S, Wakeland BE, Viswanathan K, Arana C, Liang C, Zhang B, Dozmorov I, Carr-Johnson F, Mitrovic M, Wiley GB, Kelly JA, Lauwerys BR, Olsen NJ, Cotsapas C, Garcia CK, Wise CA, Harley JB, Nath SK, James JA, Jacob CO, Tsao BP, Pasare C, Karp DR, Li QZ, Gaffney PM, Wakeland EK. Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity. Elife. 2016; 5.
    View in: PubMed
  3. Chong BF, Tseng LC, Hosler GA, Teske NM, Zhang S, Karp DR, Olsen NJ, Mohan C. A subset of CD163(+) macrophages displays mixed polarizations in discoid lupus skin. Arthritis Res Ther. 2015; 17(1):324.
    View in: PubMed
  4. Olsen NJ, Decker DA, Higgins P, Becker PM, McAloose CA, Benko AL, Kovacs WJ. Direct effects of HP Acthar Gel on human B lymphocyte activation in vitro. Arthritis Res Ther. 2015; 17:300.
    View in: PubMed
  5. Chen W, Cao H, Lin J, Olsen N, Zheng SG. Biomarkers for Primary Sjögren's Syndrome. Genomics Proteomics Bioinformatics. 2015 Aug; 13(4):219-23.
    View in: PubMed
  6. Han BK, Olsen NJ, Bottaro A. The CD27-CD70 pathway and pathogenesis of autoimmune disease. Semin Arthritis Rheum. 2016 Feb; 45(4):496-501.
    View in: PubMed
  7. Spurlock CF, Tossberg JT, Olsen NJ, Aune TM. Cutting Edge: Chronic NF-?B Activation in CD4+ T Cells in Rheumatoid Arthritis Is Genetically Determined by HLA Risk Alleles. J Immunol. 2015 Aug 1; 195(3):791-5.
    View in: PubMed
  8. Gao Y, Tang J, Chen W, Li Q, Nie J, Lin F, Wu Q, Chen Z, Gao Z, Fan H, Tsun A, Shen J, Chen G, Liu Z, Lou Z, Olsen NJ, Zheng SG, Li B. Inflammation negatively regulates FOXP3 and regulatory T-cell function via DBC1. Proc Natl Acad Sci U S A. 2015 Jun 23; 112(25):E3246-54.
    View in: PubMed
  9. Su W, Wan Q, Huang J, Han L, Chen X, Chen G, Olsen N, Zheng SG, Liang D. Culture medium from TNF-a-stimulated mesenchymal stem cells attenuates allergic conjunctivitis through multiple antiallergic mechanisms. J Allergy Clin Immunol. 2015 Aug; 136(2):423-32.e8.
    View in: PubMed
  10. Spurlock CF, Tossberg JT, Matlock BK, Olsen NJ, Aune TM. Methotrexate inhibits NF-?B activity via long intergenic (noncoding) RNA-p21 induction. Arthritis Rheumatol. 2014 Nov; 66(11):2947-57.
    View in: PubMed
  11. Gu J, Lu L, Chen M, Xu L, Lan Q, Li Q, Liu Z, Chen G, Wang P, Wang X, Brand D, Olsen N, Zheng SG. TGF-ß-induced CD4+Foxp3+ T cells attenuate acute graft-versus-host disease by suppressing expansion and killing of effector CD8+ cells. J Immunol. 2014 Oct 1; 193(7):3388-97.
    View in: PubMed
  12. Spurlock CF, Gass HM, Bryant CJ, Wells BC, Olsen NJ, Aune TM. Methotrexate-mediated inhibition of nuclear factor ?B activation by distinct pathways in T cells and fibroblast-like synoviocytes. Rheumatology (Oxford). 2015 Jan; 54(1):178-87.
    View in: PubMed
  13. Lu L, Lan Q, Li Z, Zhou X, Gu J, Li Q, Wang J, Chen M, Liu Y, Shen Y, Brand DD, Ryffel B, Horwitz DA, Quismorio FP, Liu Z, Li B, Olsen NJ, Zheng SG. Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditions. Proc Natl Acad Sci U S A. 2014 Aug 19; 111(33):E3432-40.
    View in: PubMed
  14. Olsen NJ, Elmagboul N. Neutropenia after the third cycle of etanercept: could it be due to immunogenicity? J Clin Rheumatol. 2014 Jun; 20(4):237-8.
    View in: PubMed
  15. Olsen NJ, Benko AL, Kovacs WJ. Variation in the androgen receptor gene exon 1 CAG repeat correlates with manifestations of autoimmunity in women with lupus. Endocr Connect. 2014; 3(2):99-109.
    View in: PubMed
  16. Olsen NJ, Spurlock CF, Aune TM. Methotrexate induces production of IL-1 and IL-6 in the monocytic cell line U937. Arthritis Res Ther. 2014; 16(1):R17.
    View in: PubMed
  17. Olsen NJ, Karp DR. Autoantibodies and SLE: the threshold for disease. Nat Rev Rheumatol. 2014 Mar; 10(3):181-6.
    View in: PubMed
  18. Quan J, Lakhanpal A, Reddy MM, Zaman S, Li QZ, German DC, Olsen NJ, Kodadek T, Karp DR. Discovery of biomarkers for systemic lupus erythematosus using a library of synthetic autoantigen surrogates. J Immunol Methods. 2014 Jan 15; 402(1-2):23-34.
    View in: PubMed
  19. Benko AL, Olsen NJ, Kovacs WJ. Glucocorticoid inhibition of activation-induced cytidine deaminase expression in human B lymphocytes. Mol Cell Endocrinol. 2014 Feb 15; 382(2):881-7.
    View in: PubMed
  20. Kim-Howard X, Sun C, Molineros JE, Maiti AK, Chandru H, Adler A, Wiley GB, Kaufman KM, Kottyan L, Guthridge JM, Rasmussen A, Kelly J, Sánchez E, Raj P, Li QZ, Bang SY, Lee HS, Kim TH, Kang YM, Suh CH, Chung WT, Park YB, Choe JY, Shim SC, Lee SS, Han BG, Olsen NJ, Karp DR, Moser K, Pons-Estel BA, Wakeland EK, James JA, Harley JB, Bae SC, Gaffney PM, Alarcón-Riquelme M. Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations. Hum Mol Genet. 2014 Mar 15; 23(6):1656-68.
    View in: PubMed
  21. Tossberg JT, Crooke PS, Henderson MA, Sriram S, Mrelashvili D, Vosslamber S, Verweij CL, Olsen NJ, Aune TM. Using biomarkers to predict progression from clinically isolated syndrome to multiple sclerosis. J Clin Bioinforma. 2013; 3(1):18.
    View in: PubMed
  22. Becker AM, Dao KH, Han BK, Kornu R, Lakhanpal S, Mobley AB, Li QZ, Lian Y, Wu T, Reimold AM, Olsen NJ, Karp DR, Chowdhury FZ, Farrar JD, Satterthwaite AB, Mohan C, Lipsky PE, Wakeland EK, Davis LS. SLE peripheral blood B cell, T cell and myeloid cell transcriptomes display unique profiles and each subset contributes to the interferon signature. PLoS One. 2013; 8(6):e67003.
    View in: PubMed
  23. Olsen NJ, Yousif M, Mutwally A, Cory M, Elmagboul N, Karp DR. Organ damage in high-risk patients with systemic and incomplete lupus syndromes. Rheumatol Int. 2013 Oct; 33(10):2585-90.
    View in: PubMed
  24. Olsen NJ, Schleich MA, Karp DR. Multifaceted effects of hydroxychloroquine in human disease. Semin Arthritis Rheum. 2013 Oct; 43(2):264-72.
    View in: PubMed
  25. Sakiani S, Olsen NJ, Kovacs WJ. Gonadal steroids and humoral immunity. Nat Rev Endocrinol. 2013 Jan; 9(1):56-62.
    View in: PubMed
  26. Crooke PS, Tossberg JT, Horst SN, Tauscher JL, Henderson MA, Beaulieu DB, Schwartz DA, Olsen NJ, Aune TM. Using gene expression data to identify certain gastro-intestinal diseases. J Clin Bioinforma. 2012; 2(1):20.
    View in: PubMed
  27. Benko AL, Olsen NJ, Kovacs WJ. Estrogen and telomerase in human peripheral blood mononuclear cells. Mol Cell Endocrinol. 2012 Nov 25; 364(1-2):83-8.
    View in: PubMed
  28. Olsen NJ, Li QZ, Quan J, Wang L, Mutwally A, Karp DR. Autoantibody profiling to follow evolution of lupus syndromes. Arthritis Res Ther. 2012; 14(4):R174.
    View in: PubMed
  29. Chong BF, Tseng LC, Lee T, Vasquez R, Li QZ, Zhang S, Karp DR, Olsen NJ, Mohan C. IgG and IgM autoantibody differences in discoid and systemic lupus patients. J Invest Dermatol. 2012 Dec; 132(12):2770-9.
    View in: PubMed
  30. Bellatin MF, Han M, Fallena M, Fan L, Xia D, Olsen N, Branch V, Karp D, Stastny P. Production of autoantibodies against citrullinated antigens/peptides by human B cells. J Immunol. 2012 Apr 1; 188(7):3542-50.
    View in: PubMed
  31. Graeber KE, Olsen NJ. Th17 cell cytokine secretion profile in host defense and autoimmunity. Inflamm Res. 2012 Feb; 61(2):87-96.
    View in: PubMed
  32. Spurlock CF, Tossberg JT, Fuchs HA, Olsen NJ, Aune TM. Methotrexate increases expression of cell cycle checkpoint genes via JNK activation. Arthritis Rheum. 2012 Jun; 64(6):1780-9.
    View in: PubMed
  33. Chong BF, Song J, Olsen NJ. Determining risk factors for developing systemic lupus erythematosus in patients with discoid lupus erythematosus. Br J Dermatol. 2012 Jan; 166(1):29-35.
    View in: PubMed
  34. Olsen NJ. Scleroderma: the need for extreme remedies. Am J Med Sci. 2011 Nov; 342(5):416-21.
    View in: PubMed
  35. Tossberg JT, Crooke PS, Henderson MA, Sriram S, Mrelashvili D, Chitnis S, Polman C, Vosslamber S, Verweij CL, Olsen NJ, Aune TM. Gene-expression signatures: biomarkers toward diagnosing multiple sclerosis. Genes Immun. 2012 Feb; 13(2):146-54.
    View in: PubMed
  36. Spurlock CF, Aune ZT, Tossberg JT, Collins PL, Aune JP, Huston JW, Crooke PS, Olsen NJ, Aune TM. Increased sensitivity to apoptosis induced by methotrexate is mediated by JNK. Arthritis Rheum. 2011 Sep; 63(9):2606-16.
    View in: PubMed
  37. Stoll ML, Li QZ, Zhou J, Punaro M, Olsen NJ. Elevated IgG autoantibody production in oligoarticular juvenile idiopathic arthritis may predict a refractory course. Clin Exp Rheumatol. 2011 Jul-Aug; 29(4):736-42.
    View in: PubMed
  38. Merrill JT, Wallace DJ, Petri M, Kirou KA, Yao Y, White WI, Robbie G, Levin R, Berney SM, Chindalore V, Olsen N, Richman L, Le C, Jallal B, White B. Safety profile and clinical activity of sifalimumab, a fully human anti-interferon a monoclonal antibody, in systemic lupus erythematosus: a phase I, multicentre, double-blind randomised study. Ann Rheum Dis. 2011 Nov; 70(11):1905-13.
    View in: PubMed
  39. Tessnow AH, Olsen NJ, Kovacs WJ. Expression of humoral autoimmunity is related to androgen receptor CAG repeat length in men with systemic lupus erythematosus. J Clin Immunol. 2011 Aug; 31(4):567-73.
    View in: PubMed
  40. Li QZ, Karp DR, Quan J, Branch VK, Zhou J, Lian Y, Chong BF, Wakeland EK, Olsen NJ. Risk factors for ANA positivity in healthy persons. Arthritis Res Ther. 2011; 13(2):R38.
    View in: PubMed
  41. Olsen NJ. Nutraceuticals for the treatment of osteoarthritis. Minerva Med. 2011 Feb; 102(1):33-40.
    View in: PubMed
  42. Kovacs WJ, Olsen NJ. Sexual dimorphism of RA manifestations: genes, hormones and behavior. Nat Rev Rheumatol. 2011 May; 7(5):307-10.
    View in: PubMed
  43. Olsen NJ, Kovacs WJ. Evidence that androgens modulate human thymic T cell output. J Investig Med. 2011 Jan; 59(1):32-5.
    View in: PubMed
  44. Olsen NJ, Branch VK, Jonnala G, Seskar M, Cooper M. Phase 1, placebo-controlled, dose escalation trial of chicory root extract in patients with osteoarthritis of the hip or knee. BMC Musculoskelet Disord. 2010; 11:156.
    View in: PubMed
  45. McMahan ZH, Sailors JL, Toto R, Olsen NJ. Systemic amyloidosis presenting as chronic diarrhea in a patient with ankylosing spondylitis. J Clin Rheumatol. 2010 Jan; 16(1):22-5.
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  46. Li QZ, Zhou J, Lian Y, Zhang B, Branch VK, Carr-Johnson F, Karp DR, Mohan C, Wakeland EK, Olsen NJ. Interferon signature gene expression is correlated with autoantibody profiles in patients with incomplete lupus syndromes. Clin Exp Immunol. 2010 Mar; 159(3):281-91.
    View in: PubMed
  47. Goldbach-Mansky R, Wilson M, Fleischmann R, Olsen N, Silverfield J, Kempf P, Kivitz A, Sherrer Y, Pucino F, Csako G, Costello R, Pham TH, Snyder C, van der Heijde D, Tao X, Wesley R, Lipsky PE. Comparison of Tripterygium wilfordii Hook F versus sulfasalazine in the treatment of rheumatoid arthritis: a randomized trial. Ann Intern Med. 2009 Aug 18; 151(4):229-40, W49-51.
    View in: PubMed
  48. Liu Z, Sokka T, Maas K, Olsen NJ, Aune TM. Prediction of disease severity in patients with early rheumatoid arthritis by gene expression profiling. Hum Genomics Proteomics. 2009; 2009.
    View in: PubMed
  49. Thudi A, Yin S, Wandstrat AE, Li QZ, Olsen NJ. Vitamin D levels and disease status in Texas patients with systemic lupus erythematosus. Am J Med Sci. 2008 Feb; 335(2):99-104.
    View in: PubMed
  50. Qi J, Olsen NJ, Price RR, Winston JA, Park JH. Diffusion-weighted imaging of inflammatory myopathies: polymyositis and dermatomyositis. J Magn Reson Imaging. 2008 Jan; 27(1):212-7.
    View in: PubMed
  51. Fossey SC, Vnencak-Jones CL, Olsen NJ, Sriram S, Garrison G, Deng X, Crooke PS, Aune TM. Identification of molecular biomarkers for multiple sclerosis. J Mol Diagn. 2007 Apr; 9(2):197-204.
    View in: PubMed
  52. Li QZ, Zhou J, Wandstrat AE, Carr-Johnson F, Branch V, Karp DR, Mohan C, Wakeland EK, Olsen NJ. Protein array autoantibody profiles for insights into systemic lupus erythematosus and incomplete lupus syndromes. Clin Exp Immunol. 2007 Jan; 147(1):60-70.
    View in: PubMed
  53. Wandstrat AE, Carr-Johnson F, Branch V, Gray H, Fairhurst AM, Reimold A, Karp D, Wakeland EK, Olsen NJ. Autoantibody profiling to identify individuals at risk for systemic lupus erythematosus. J Autoimmun. 2006 Nov; 27(3):153-60.
    View in: PubMed
  54. Stanic AK, Stein CM, Morgan AC, Fazio S, Linton MF, Wakeland EK, Olsen NJ, Major AS. Immune dysregulation accelerates atherosclerosis and modulates plaque composition in systemic lupus erythematosus. Proc Natl Acad Sci U S A. 2006 May 2; 103(18):7018-23.
    View in: PubMed
  55. Liu Z, Yelverton RW, Kraft B, Tanner SB, Olsen NJ, Aune TM. Highly conserved gene expression profiles in humans with allergic rhinitis altered by immunotherapy. Clin Exp Allergy. 2005 Dec; 35(12):1581-90.
    View in: PubMed
  56. Maas K, Chen H, Shyr Y, Olsen NJ, Aune T. Shared gene expression profiles in individuals with autoimmune disease and unaffected first-degree relatives of individuals with autoimmune disease. Hum Mol Genet. 2005 May 15; 14(10):1305-14.
    View in: PubMed
  57. Maas K, Westfall M, Pietenpol J, Olsen NJ, Aune T. Reduced p53 in peripheral blood mononuclear cells from patients with rheumatoid arthritis is associated with loss of radiation-induced apoptosis. Arthritis Rheum. 2005 Apr; 52(4):1047-57.
    View in: PubMed
  58. Olsen N, Sokka T, Seehorn CL, Kraft B, Maas K, Moore J, Aune TM. A gene expression signature for recent onset rheumatoid arthritis in peripheral blood mononuclear cells. Ann Rheum Dis. 2004 Nov; 63(11):1387-92.
    View in: PubMed
  59. Olsen NJ. Drug-induced autoimmunity. Best Pract Res Clin Rheumatol. 2004 Oct; 18(5):677-88.
    View in: PubMed
  60. Aune TM, Parker JS, Maas K, Liu Z, Olsen NJ, Moore JH. Co-localization of differentially expressed genes and shared susceptibility loci in human autoimmunity. Genet Epidemiol. 2004 Sep; 27(2):162-72.
    View in: PubMed
  61. Olsen NJ, Stein CM. New drugs for rheumatoid arthritis. N Engl J Med. 2004 May 20; 350(21):2167-79.
    View in: PubMed
  62. Olsen NJ, Moore JH, Aune TM. Gene expression signatures for autoimmune disease in peripheral blood mononuclear cells. Arthritis Res Ther. 2004; 6(3):120-8.
    View in: PubMed
  63. Aune TM, Maas K, Parker J, Moore JH, Olsen NJ. Profiles of gene expression in human autoimmune disease. Cell Biochem Biophys. 2004; 40(2):81-96.
    View in: PubMed
  64. Asanuma Y, Oeser A, Shintani AK, Turner E, Olsen N, Fazio S, Linton MF, Raggi P, Stein CM. Premature coronary-artery atherosclerosis in systemic lupus erythematosus. N Engl J Med. 2003 Dec 18; 349(25):2407-15.
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  65. Drake WP, Byrd VM, Olsen NJ. Reactivation of systemic lupus erythematosus after initiation of highly active antiretroviral therapy for acquired immunodeficiency syndrome. J Clin Rheumatol. 2003 Jun; 9(3):176-80.
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  66. Kavanaugh A, Genovese M, Baughman J, Kivitz A, Bulpitt K, Olsen N, Weisman M, Matteson E, Furst D, van Vollenhoven R, Anderson J, Cohen S, Wei N, Meijerink J, Jacobs C, Mocci S. Allele and antigen-specific treatment of rheumatoid arthritis: a double blind, placebo controlled phase 1 trial. J Rheumatol. 2003 Mar; 30(3):449-54.
    View in: PubMed
  67. Aune TM, Maas K, Moore JH, Olsen NJ. Gene expression profiles in human autoimmune disease. Curr Pharm Des. 2003; 9(23):1905-17.
    View in: PubMed
  68. Brogan BL, Olsen NJ. Drug-induced rheumatic syndromes. Curr Opin Rheumatol. 2003 Jan; 15(1):76-80.
    View in: PubMed
  69. Maas K, Chan S, Parker J, Slater A, Moore J, Olsen N, Aune TM. Cutting edge: molecular portrait of human autoimmune disease. J Immunol. 2002 Jul 1; 169(1):5-9.
    View in: PubMed
  70. Olsen NJ, Kovacs WJ. Hormones, pregnancy, and rheumatoid arthritis. J Gend Specif Med. 2002 Jul-Aug; 5(4):28-37.
    View in: PubMed
  71. Moore JH, Parker JS, Olsen NJ, Aune TM. Symbolic discriminant analysis of microarray data in autoimmune disease. Genet Epidemiol. 2002 Jun; 23(1):57-69.
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  72. Olsen NJ, Gu X, Kovacs WJ. Bone marrow stromal cells mediate androgenic suppression of B lymphocyte development. J Clin Invest. 2001 Dec; 108(11):1697-704.
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  73. Cohen S, Cannon GW, Schiff M, Weaver A, Fox R, Olsen N, Furst D, Sharp J, Moreland L, Caldwell J, Kaine J, Strand V. Two-year, blinded, randomized, controlled trial of treatment of active rheumatoid arthritis with leflunomide compared with methotrexate. Utilization of Leflunomide in the Treatment of Rheumatoid Arthritis Trial Investigator Group. Arthritis Rheum. 2001 Sep; 44(9):1984-92.
    View in: PubMed
  74. Park JH, Olsen NJ. Utility of magnetic resonance imaging in the evaluation of patients with inflammatory myopathies. Curr Rheumatol Rep. 2001 Aug; 3(4):334-45.
    View in: PubMed
  75. Olsen NJ, Park JH, King LE. Amyopathic dermatomyositis. Curr Rheumatol Rep. 2001 Aug; 3(4):346-51.
    View in: PubMed
  76. Holla VR, Adas F, Imig JD, Zhao X, Price E, Olsen N, Kovacs WJ, Magnuson MA, Keeney DS, Breyer MD, Falck JR, Waterman MR, Capdevila JH. Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension. Proc Natl Acad Sci U S A. 2001 Apr 24; 98(9):5211-6.
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  77. Olsen NJ, Olson G, Viselli SM, Gu X, Kovacs WJ. Androgen receptors in thymic epithelium modulate thymus size and thymocyte development. Endocrinology. 2001 Mar; 142(3):1278-83.
    View in: PubMed
  78. Olsen NJ, Kovacs WJ. Effects of androgens on T and B lymphocyte development. Immunol Res. 2001; 23(2-3):281-8.
    View in: PubMed
  79. St Clair EW, Cohen SB, Lee ML, Fleischmann RM, Lee SH, Moreland LW, Olsen NJ, Pratt PW, Yocum DE, Heck L, Winkelhake J, Holcenberg JS, Shulman MJ. Treatment of rheumatoid arthritis with a DR4/1 peptide. J Rheumatol. 2000 Aug; 27(8):1855-63.
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  80. Park JH, Niermann KJ, Olsen N. Evidence for metabolic abnormalities in the muscles of patients with fibromyalgia. Curr Rheumatol Rep. 2000 Apr; 2(2):131-40.
    View in: PubMed
  81. Strand V, Cohen S, Schiff M, Weaver A, Fleischmann R, Cannon G, Fox R, Moreland L, Olsen N, Furst D, Caldwell J, Kaine J, Sharp J, Hurley F, Loew-Friedrich I. Treatment of active rheumatoid arthritis with leflunomide compared with placebo and methotrexate. Leflunomide Rheumatoid Arthritis Investigators Group. Arch Intern Med. 1999 Nov 22; 159(21):2542-50.
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  82. Olsen NJ, Strand V, Kremer JM. Leflunomide for the treatment of rheumatoid arthritis. Bull Rheum Dis. 1999; 48(8):1-4.
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  83. Park JH, Kari S, King LE, Olsen NJ. Analysis of 31P MR spectroscopy data using artificial neural networks for longitudinal evaluation of muscle diseases: dermatomyositis. NMR Biomed. 1998 Jun-Aug; 11(4-5):245-56.
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  84. Olsen NJ, Park JH. Skeletal muscle abnormalities in patients with fibromyalgia. Am J Med Sci. 1998 Jun; 315(6):351-8.
    View in: PubMed
  85. Park JH, Phothimat P, Oates CT, Hernanz-Schulman M, Olsen NJ. Use of P-31 magnetic resonance spectroscopy to detect metabolic abnormalities in muscles of patients with fibromyalgia. Arthritis Rheum. 1998 Mar; 41(3):406-13.
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  86. Olsen NJ, Viselli SM, Fan J, Kovacs WJ. Androgens accelerate thymocyte apoptosis. Endocrinology. 1998 Feb; 139(2):748-52.
    View in: PubMed
  87. Park J, Bank W, Lech G, Long H, Olsen N, Chance B. Correlative magnetic resonance and near-infrared technologies for the evaluation of mitochondrial disease. Biofactors. 1998; 7(3):253-4.
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  88. Viselli SM, Reese KR, Fan J, Kovacs WJ, Olsen NJ. Androgens alter B cell development in normal male mice. Cell Immunol. 1997 Dec 15; 182(2):99-104.
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  89. Olsen NJ, Park JH. Inflammatory myopathies: issues in diagnosis and management. Arthritis Care Res. 1997 Jun; 10(3):200-7.
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  90. Nakazawa M, Fantappie MR, Freeman GL, Eloi-Santos S, Olsen NJ, Kovacs WJ, Secor WE, Colley DG. Schistosoma mansoni: susceptibility differences between male and female mice can be mediated by testosterone during early infection. Exp Parasitol. 1997 Mar; 85(3):233-40.
    View in: PubMed
  91. Olsen NJ, King LE, Park JH. Muscle abnormalities in scleroderma. Rheum Dis Clin North Am. 1996 Nov; 22(4):783-96.
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  92. Olsen NJ, Kovacs WJ. Gonadal steroids and immunity. Endocr Rev. 1996 Aug; 17(4):369-84.
    View in: PubMed
  93. Kari S, Olsen NJ, Park JH. Evaluation of muscle diseases using artificial neural network analysis of 31P MR spectroscopy data. Magn Reson Med. 1995 Nov; 34(5):664-72.
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  94. Olsen NJ, Kovacs WJ. Case report: testosterone treatment of systemic lupus erythematosus in a patient with Klinefelter's syndrome. Am J Med Sci. 1995 Oct; 310(4):158-60.
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  95. Adams LB, Park JH, Olsen NJ, Gardner ES, Hernanz-Schulman M, King LE. Quantitative evaluation of improvement in muscle weakness in a patient receiving extracorporeal photopheresis for scleroderma: magnetic resonance imaging and magnetic resonance spectroscopy. J Am Acad Dermatol. 1995 Sep; 33(3):519-22.
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  96. Olsen NJ, Park JH. MRS and NIRS for muscle disease evaluation. Bull Rheum Dis. 1995 Aug; 44(5):4-7.
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  97. Viselli SM, Olsen NJ, Shults K, Steizer G, Kovacs WJ. Immunochemical and flow cytometric analysis of androgen receptor expression in thymocytes. Mol Cell Endocrinol. 1995 Mar; 109(1):19-26.
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  98. Viselli SM, Stanziale S, Shults K, Kovacs WJ, Olsen NJ. Castration alters peripheral immune function in normal male mice. Immunology. 1995 Feb; 84(2):337-42.
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  99. Park JH, Olsen NJ, King L, Vital T, Buse R, Kari S, Hernanz-Schulman M, Price RR. Use of magnetic resonance imaging and P-31 magnetic resonance spectroscopy to detect and quantify muscle dysfunction in the amyopathic and myopathic variants of dermatomyositis. Arthritis Rheum. 1995 Jan; 38(1):68-77.
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  100. Moore S, Ruska K, Peters L, Olsen NJ. Associations of IgA and IgA-rheumatoid factor with disease features in patients with rheumatoid arthritis. Immunol Invest. 1994 Nov; 23(6-7):355-65.
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  101. Fava RA, Olsen NJ, Spencer-Green G, Yeo KT, Yeo TK, Berse B, Jackman RW, Senger DR, Dvorak HF, Brown LF. Vascular permeability factor/endothelial growth factor (VPF/VEGF): accumulation and expression in human synovial fluids and rheumatoid synovial tissue. J Exp Med. 1994 Jul 1; 180(1):341-6.
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  102. King LE, Park JH, Adams L, Vital T, Olsen NJ. Evaluation of muscles in a patient with suspected amyopathic dermatomyositis by magnetic resonance imaging and phosphorus-31-spectroscopy. J Am Acad Dermatol. 1994 Jan; 30(1):137-8.
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  103. Olsen NJ, Viselli SM, Shults K, Stelzer G, Kovacs WJ. Induction of immature thymocyte proliferation after castration of normal male mice. Endocrinology. 1994 Jan; 134(1):107-13.
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  104. Olsen NJ, Brooks RH, Furst D. Variability of immunologic and clinical features in patients with rheumatoid arthritis studied over 24 hours. J Rheumatol. 1993 Jun; 20(6):940-3.
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  105. Strand V, Lipsky PE, Cannon GW, Calabrese LH, Wiesenhutter C, Cohen SB, Olsen NJ, Lee ML, Lorenz TJ, Nelson B. Effects of administration of an anti-CD5 plus immunoconjugate in rheumatoid arthritis. Results of two phase II studies. The CD5 Plus Rheumatoid Arthritis Investigators Group. Arthritis Rheum. 1993 May; 36(5):620-30.
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  106. Olsen NJ, Zhou P, Ong H, Kovacs WJ. Testosterone induces expression of transforming growth factor-beta 1 in the murine thymus. J Steroid Biochem Mol Biol. 1993 May; 45(5):327-32.
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  107. Olsen NJ, Nicholson WE, DeBold CR, Orth DN. Lymphocyte-derived adrenocorticotropin is insufficient to stimulate adrenal steroidogenesis in hypophysectomized rats. Endocrinology. 1992 Apr; 130(4):2113-9.
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  108. Olsen NJ, Watson MB, Henderson GS, Kovacs WJ. Androgen deprivation induces phenotypic and functional changes in the thymus of adult male mice. Endocrinology. 1991 Nov; 129(5):2471-6.
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  109. Peters LJ, Olsen NJ. Mechanisms of action of methotrexate. Bull Rheum Dis. 1991 Oct; 41(6):5-8.
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  110. Olsen NJ, Teal GP, Brooks RH. IgM-rheumatoid factor and responses to second-line drugs in rheumatoid arthritis. Agents Actions. 1991 Sep; 34(1-2):169-71.
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  111. Olsen NJ, Watson MB, Kovacs WJ. Studies of immunological function in mice with defective androgen action. Distinction between alterations in immune function due to hormonal insensitivity and alterations due to other genetic factors. Immunology. 1991 May; 73(1):52-7.
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  112. May DG, Black CM, Olsen NJ, Csuka ME, Tanner SB, Bellino L, Porter JA, Wilkinson GR, Branch RA. Scleroderma is associated with differences in individual routes of drug metabolism: a study with dapsone, debrisoquin, and mephenytoin. Clin Pharmacol Ther. 1990 Sep; 48(3):286-95.
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  113. Olsen NJ, Kovacs WJ. Increased thymic size and thymocyte interleukin 2 production in androgen-resistant mice. Scand J Immunol. 1989 Jun; 29(6):733-8.
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  114. Olsen NJ, Murray LM. Antiproliferative effects of methotrexate on peripheral blood mononuclear cells. Arthritis Rheum. 1989 Apr; 32(4):378-85.
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  115. Kovacs WJ, Olsen NJ. Androgen receptors in human thymocytes. J Immunol. 1987 Jul 15; 139(2):490-3.
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  116. Olsen NJ, Jasin HE. Synthesis of rheumatoid factor in vitro: implications for the pathogenesis of rheumatoid arthritis. Semin Arthritis Rheum. 1985 Nov; 15(2):146-56.
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  117. Olsen N, Ziff M, Jasin HE. In vitro synthesis of immunoglobulins and IgM-rheumatoid factor by blood mononuclear cells of patients with rheumatoid arthritis. Rheumatol Int. 1982; 2(2):59-66.
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