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Karam El bayoumy
Title Professor
Institution College of Medicine
Department Biochemistry and Molecular Biology
Division Biochemistry/Molecular Biology
Address 500 University Drive Hershey PA 17033
Mailbox: CH72
Telephone 7175311005
Email
Background
PREFERRED TITLE/ROLE:

Distinguished Professor

SECONDARY APPOINTMENT(S)/ INSTITUTE(S)/ CENTER(S):

Penn State Hershey Cancer Institute, Chemical Carcinogenesis and Chemoprevention

GRADUATE PROGRAM AFFILIATIONS:

Biochemistry and Molecular Biology

EDUCATION:

B. S., Ain Shams University, Cairo, Egypt, (with honors), 1968-1970, Chemistry
M.S., New York University, NY, 1975, Organic Chemistry
Ph.D., New York University, NY, 1978, Physical Organic Chemistry
Publications
1. Jiang W, Zhu Z, McGinley JN, El Bayoumy K, Manni A, Thompson HJ. Identification of a molecular signature underlying inhibition of mammary carcinoma growth by dietary N-3 fatty acids. Cancer Res. 2012 Aug 1; 72(15):3795-806.
  View in: PubMed
 
2. Chen KM, Zhang SM, Aliaga C, Sun YW, Cooper T, Gowdahalli K, Zhu J, Amin S, El-Bayoumy K. Induction of ovarian cancer and DNA adducts by Dibenzo[a,l]pyrene in the mouse. Chem Res Toxicol. 2012 Feb 20; 25(2):374-80.
  View in: PubMed
 
3. Trushin N, Alam S, El-Bayoumy K, Krzeminski J, Amin SG, Gullett J, Meyers C, Prokopczyk B . J. Carcinogenesis. Comparative metabolism of benzo[a]pyrected with high-risk human papillomavirus types 16 and 18 as episomal or integrated genomes. 2012; 11:1-9.
 
4. Richie JP, Das A, Calcagnotto AM, Aliaga CA, El-Bayoumy K. Age related changes in selenium and glutathione levels in different lobes of the rat prostate. Exp Gerontol. 2012 Mar; 47(3):223-8.
  View in: PubMed
 
5. Guttenplan JB, Kosinska W, Zhao ZL, Chen KM, Aliaga C, DelTondo J, Cooper T, Sun YW, Zhang SM, Jiang K, Bruggeman R, Sharma AK, Amin S, Ahn K, El-Bayoumy K. Mutagenesis and carcinogenesis induced by dibenzo[a,l]pyrene in the mouse oral cavity: a potential new model for oral cancer. Int J Cancer. 2012 Jun 15; 130(12):2783-90.
  View in: PubMed
 
6. El-Bayoumy K, Das A, Russell S, Wolfe S, Jordan R, Renganathan K, Loughran TP, Somiari R. The effect of selenium enrichment on baker's yeast proteome. J Proteomics. 2012 Jan 4; 75(3):1018-30.
  View in: PubMed
 
7. Zhu Z, Jiang W, McGinley JN, Prokopczyk B, Richie JP, El Bayoumy K, Manni A, Thompson HJ. Mammary gland density predicts the cancer inhibitory activity of the N-3 to N-6 ratio of dietary fat. Cancer Prev Res (Phila). 2011 Oct; 4(10):1675-85.
  View in: PubMed
 
8. Manni A, Xu H, Washington S, Aliaga C, Das A, Cooper T, Richie JP, Prokopczyk B, Calcagnotto A, Trushin N, Van den Heuvel JP, Hamilton C, Demers LM, Liao J, Verderame MF, El-Bayoumy K. The effects of Tamoxifen and fish oil on mammary carcinogenesis in polyoma middle T transgenic mice. Horm Cancer. 2011 Aug; 2(4):249-59.
  View in: PubMed
 
9. Manni A, Richie JP, Xu H, Washington S, Aliaga C, Cooper TK, Bruggeman R, Das A, Prokopczyk B, Calcagnotto A, Trushin N, Dickinson R, Liao J, Verderame MF, El-Bayoumy K. Effects of fish oil and Tamoxifen on preneoplastic lesion development and biomarkers of oxidative stress in the early stages of N-methyl-N-nitrosourea-induced rat mammary carcinogenesis. Int J Oncol. 2011 Nov; 39(5):1153-64.
  View in: PubMed
 
10. Zhang SM, Chen KM, Aliaga C, Sun YW, Lin JM, Sharma AK, Amin S, El-Bayoumy K. Identification and quantification of DNA adducts in the oral tissues of mice treated with the environmental carcinogen dibenzo[a,l]pyrene by HPLC-MS/MS. Chem Res Toxicol. 2011 Aug 15; 24(8):1297-303.
  View in: PubMed
 
11. Bortner JD, Richie JP, Das A, Liao J, Umstead TM, Stanley A, Stanley BA, Belani CP, El-Bayoumy K. Proteomic profiling of human plasma by iTRAQ reveals down-regulation of ITI-HC3 and VDBP by cigarette smoking. J Proteome Res. 2011 Mar 4; 10(3):1151-9.
  View in: PubMed
 
12. Richie JP, Muscat JE, Ellison I, Calcagnotto A, Kleinman W, El-Bayoumy K. Association of selenium status and blood glutathione concentrations in blacks and whites. Nutr Cancer. 2011; 63(3):367-75.
  View in: PubMed
 
13. Krzeminski J, Kropachev K, Kolbanovskiy M, Reeves D, Kolbanovskiy A, Yun BH, Geacintov NE, Amin S, El-Bayoumy K. Inefficient nucleotide excision repair in human cell extracts of the N-(deoxyguanosin-8-yl)-6-aminochrysene and 5-(deoxyguanosin-N(2)-yl)-6-aminochrysene adducts derived from 6-nitrochrysene. Chem Res Toxicol. 2011 Jan 14; 24(1):65-72.
  View in: PubMed
 
14. Desai D, Kaushal N, Gandhi UH, Arner RJ, D'Souza C, Chen G, Vunta H, El-Bayoumy K, Amin S, Prabhu KS. Synthesis and evaluation of the anti-inflammatory properties of selenium-derivatives of celecoxib. Chem Biol Interact. 2010 Dec 5; 188(3):446-56.
  View in: PubMed
 
15. Sinha R, Sinha I, Facompre N, Russell S, Somiari RI, Richie JP, El-Bayoumy K. Selenium-responsive proteins in the sera of selenium-enriched yeast-supplemented healthy African American and Caucasian men. Cancer Epidemiol Biomarkers Prev. 2010 Sep; 19(9):2332-40.
  View in: PubMed
 
16. Facompre ND, El-Bayoumy K, Sun YW, Pinto JT, Sinha R. 1,4-phenylenebis(methylene)selenocyanate, but not selenomethionine, inhibits androgen receptor and Akt signaling in human prostate cancer cells. Cancer Prev Res (Phila). 2010 Aug; 3(8):975-84.
  View in: PubMed
 
 
Keyword
Last Name
Institution
    
 
 
 
Keywords   
Selenium
Benzopyrenes
DNA Adducts
Mammary Neoplasms, Experimental
Glutathione
See all (134) keywords
Co-Authors  
Aliaga, Cesar
Amin, Shantu
Cooper, Timothy
Das, Arunangshu
Richie, John
See all (25) people
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