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Arunangshu Das
Title Assistant Professor
Institution College of Medicine
Department Biochemistry and Molecular Biology
Division Biochemistry/Molecular Biology
Address 500 University Drive Hershey PA 17033
Mailbox: CH76
Telephone 7175314664
Email
Background
PREFERRED TITLE/ROLE:

Assistant Professor of Biochemistry and Molecular Biology

SECONDARY APPOINTMENT(S)/ INSTITUTE(S)/ CENTER(S):

Penn State Hershey Cancer Center, Chemical Carcinogenesis and Chemoprevention

GRADUATE PROGRAM AFFILIATIONS:

Biochemistry and Molecular Biology

EDUCATION:

M.S., Jadavpur University, India, 1990
Ph. D., Jadavpur University, India, 1996
Publications
1. Das AK, Yang QY, Fu X, Liang JF, Duarte MS, Zhu MJ, Trobridge GD, Du M. AMP-activated protein kinase stimulates myostatin expression in C2C12 cells. Biochem Biophys Res Commun. 2012 Oct 12; 427(1):36-40.
  View in: PubMed
 
2. Das A, Bortner JD, Aliaga CA, Baker A, Stanley A, Stanley BA, Kaag M, Richie JP, El-Bayoumy K. Changes in proteomic profiles in different prostate lobes of male rats throughout growth and development and aging stages of the life span. Prostate. 2013 Mar; 73(4):363-75.
  View in: PubMed
 
3. Emmert SW, El-Bayoumy K, Das A, Sun YW, Amin S, Desai D, Aliaga C, Richie JP. Induction of lung glutathione and glutamylcysteine ligase by 1,4-phenylenebis(methylene)selenocyanate and its glutathione conjugate: role of nuclear factor-erythroid 2-related factor 2. Free Radic Biol Med. 2012 May 15; 52(10):2064-71.
  View in: PubMed
 
4. Richie JP, Das A, Calcagnotto AM, Aliaga CA, El-Bayoumy K. Age related changes in selenium and glutathione levels in different lobes of the rat prostate. Exp Gerontol. 2012 Mar; 47(3):223-8.
  View in: PubMed
 
5. El-Bayoumy K, Das A, Russell S, Wolfe S, Jordan R, Renganathan K, Loughran TP, Somiari R. The effect of selenium enrichment on baker's yeast proteome. J Proteomics. 2012 Jan 4; 75(3):1018-30.
  View in: PubMed
 
6. Manni A, Xu H, Washington S, Aliaga C, Das A, Cooper T, Richie JP, Prokopczyk B, Calcagnotto A, Trushin N, Van den Heuvel JP, Hamilton C, Demers LM, Liao J, Verderame MF, El-Bayoumy K. The effects of Tamoxifen and fish oil on mammary carcinogenesis in polyoma middle T transgenic mice. Horm Cancer. 2011 Aug; 2(4):249-59.
  View in: PubMed
 
7. Crampsie MA, Jones N, Das A, Aliaga C, Desai D, Lazarus P, Amin S, Sharma AK. Phenylbutyl isoselenocyanate modulates phase I and II enzymes and inhibits 4-(methylnitrosamino)-1-(3-pyridyl)- 1-butanone-induced DNA adducts in mice. Cancer Prev Res (Phila). 2011 Nov; 4(11):1884-94.
  View in: PubMed
 
8. Manni A, Richie JP, Xu H, Washington S, Aliaga C, Cooper TK, Bruggeman R, Das A, Prokopczyk B, Calcagnotto A, Trushin N, Dickinson R, Liao J, Verderame MF, El-Bayoumy K. Effects of fish oil and Tamoxifen on preneoplastic lesion development and biomarkers of oxidative stress in the early stages of N-methyl-N-nitrosourea-induced rat mammary carcinogenesis. Int J Oncol. 2011 Nov; 39(5):1153-64.
  View in: PubMed
 
9. Bortner JD, Richie JP, Das A, Liao J, Umstead TM, Stanley A, Stanley BA, Belani CP, El-Bayoumy K. Proteomic profiling of human plasma by iTRAQ reveals down-regulation of ITI-HC3 and VDBP by cigarette smoking. J Proteome Res. 2011 Mar 4; 10(3):1151-9.
  View in: PubMed
 
10. Bortner JD, Das A, Umstead TM, Freeman WM, Somiari R, Aliaga C, Phelps DS, El-Bayoumy K. Down-regulation of 14-3-3 isoforms and annexin A5 proteins in lung adenocarcinoma induced by the tobacco-specific nitrosamine NNK in the A/J mouse revealed by proteomic analysis. J Proteome Res. 2009 Aug; 8(8):4050-61.
  View in: PubMed
 
11. Chen KM, Sacks PG, Spratt TE, Lin JM, Boyiri T, Schwartz J, Richie JP, Calcagnotto A, Das A, Bortner J, Zhao Z, Amin S, Guttenplan J, El-Bayoumy K. Modulations of benzo[a]pyrene-induced DNA adduct, cyclin D1 and PCNA in oral tissue by 1,4-phenylenebis(methylene)selenocyanate. Biochem Biophys Res Commun. 2009 May 22; 383(1):151-5.
  View in: PubMed
 
12. Das A, Bortner J, Desai D, Amin S, El-Bayoumy K. The selenium analog of the chemopreventive compound S,S'-(1,4-phenylenebis[1,2-ethanediyl])bisisothiourea is a remarkable inducer of apoptosis and inhibitor of cell growth in human non-small cell lung cancer. Chem Biol Interact. 2009 Jul 15; 180(2):158-64.
  View in: PubMed
 
13. Chen KM, Spratt TE, Stanley BA, De Cotiis DA, Bewley MC, Flanagan JM, Desai D, Das A, Fiala ES, Amin S, El-Bayoumy K. Inhibition of nuclear factor-kappaB DNA binding by organoselenocyanates through covalent modification of the p50 subunit. Cancer Res. 2007 Nov 1; 67(21):10475-83.
  View in: PubMed
 
14. Richie JP, Kleinman W, Desai DH, Das A, Amin SG, Pinto JT, El-Bayoumy K. The organoselenium compound 1,4-phenylenebis(methylene)selenocyanate inhibits 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced tumorgenesis and enhances glutathione-related antioxidant levels in A/J mouse lung. Chem Biol Interact. 2006 Jun 10; 161(2):93-103.
  View in: PubMed
 
15. El-Bayoumy K, Das A, Narayanan B, Narayanan N, Fiala ES, Desai D, Rao CV, Amin S, Sinha R. Molecular targets of the chemopreventive agent 1,4-phenylenebis (methylene)-selenocyanate in human non-small cell lung cancer. Carcinogenesis. 2006 Jul; 27(7):1369-76.
  View in: PubMed
 
16. Utzat CD, Clement CC, Ramos LA, Das A, Tomasz M, Basu AK. DNA adduct of the mitomycin C metabolite 2,7-diaminomitosene is a nontoxic and nonmutagenic DNA lesion in vitro and in vivo. Chem Res Toxicol. 2005 Feb; 18(2):213-23.
  View in: PubMed
 
17. Sohn OS, Desai DH, Das A, Rodriguez JG, Amin SG, El-Bayoumy K. Comparative excretion and tissue distribution of selenium in mice and rats following treatment with the chemopreventive agent 1,4-phenylenebis(methylene)selenocyanate. Chem Biol Interact. 2005 Feb 10; 151(3):193-202.
  View in: PubMed
 
18. El-Bayoumy K, Das A, Boyiri T, Desai D, Sinha R, Pittman B, Amin S. Comparative action of 1,4-phenylenebis(methylene)selenocyanate and its metabolites against 7,12-dimethylbenz[a]anthracene-DNA adduct formation in the rat and cell proliferation in rat mammary tumor cells. Chem Biol Interact. 2003 Oct 25; 146(2):179-90.
  View in: PubMed
 
19. Das A, Desai D, Pittman B, Amin S, El-Bayoumy K. Comparison of the chemopreventive efficacies of 1,4-phenylenebis(methylene)selenocyanate and selenium-enriched yeast on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced lung tumorigenesis in A/J mouse. Nutr Cancer. 2003; 46(2):179-85.
  View in: PubMed
 
20. Desai D, Das A, Cohen L, el-Bayoumy K, Amin S. Chemopreventive efficacy of suberoylanilide hydroxamic acid (SAHA) against 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumorigenesis in female A/J mice. Anticancer Res. 2003 Jan-Feb; 23(1A):499-503.
  View in: PubMed
 
 
Keyword
Last Name
Institution
    
 
 
 
Keywords   
Organoselenium Compounds
Anticarcinogenic Agents
Selenium
Carcinogens
Urea
See all (151) keywords
Co-Authors  
Aliaga, Cesar
Amin, Shantu
Desai, Dhimant
El bayoumy, Karam
Richie, John
See all (24) people
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