|
1.
|
Hengst JA, Yun JK. Sphingosine kinase: a key to solving the 'French Paradox'? Br J Pharmacol. 2012 Jul; 166(5):1603-4.
|
|
|
|
|
2.
|
Mahmoud S, Yun JK, Ruiz-Velasco V. Gß2 and Gß4 participate in the opioid and adrenergic receptor-mediated Ca2+ channel modulation in rat sympathetic neurons. J Physiol. 2012 Oct 1; 590(Pt 19):4673-89.
|
|
|
|
|
3.
|
Madhunapantula SV, Hengst J, Gowda R, Fox TE, Yun JK, Robertson GP. Targeting sphingosine kinase-1 to inhibit melanoma. Pigment Cell Melanoma Res. 2012 Mar; 25(2):259-74.
|
|
|
|
|
4.
|
Sk UH, Prakasha Gowda AS, Crampsie MA, Yun JK, Spratt TE, Amin S, Sharma AK. Development of novel naphthalimide derivatives and their evaluation as potential melanoma therapeutics. Eur J Med Chem. 2011 Aug; 46(8):3331-8.
|
|
|
|
|
5.
|
O'Neill SM, Yun JK, Fox TE, Kester M. Transcriptional regulation of the human neutral ceramidase gene. Arch Biochem Biophys. 2011 Jul; 511(1-2):21-30.
|
|
|
|
|
6.
|
O'Neill SM, Houck KL, Yun JK, Fox TE, Kester M. AP-1 binding transcriptionally regulates human neutral ceramidase. Arch Biochem Biophys. 2011 Jul; 511(1-2):31-9.
|
|
|
|
|
7.
|
Hengst JA, Wang X, Sk UH, Sharma AK, Amin S, Yun JK. Development of a sphingosine kinase 1 specific small-molecule inhibitor. Bioorg Med Chem Lett. 2010 Dec 15; 20(24):7498-502.
|
|
|
|
|
8.
|
Hengst JA, Guilford JM, Conroy EJ, Wang X, Yun JK. Enhancement of sphingosine kinase 1 catalytic activity by deletion of 21 amino acids from the COOH-terminus. Arch Biochem Biophys. 2010 Feb 1; 494(1):23-31.
|
|
|
|
|
9.
|
Hengst JA, Guilford JM, Fox TE, Wang X, Conroy EJ, Yun JK. Sphingosine kinase 1 localized to the plasma membrane lipid raft microdomain overcomes serum deprivation induced growth inhibition. Arch Biochem Biophys. 2009 Dec; 492(1-2):62-73.
|
|
|
|
|
10.
|
Morgan TT, Muddana HS, Altinoglu EI, Rouse SM, Tabakovic A, Tabouillot T, Russin TJ, Shanmugavelandy SS, Butler PJ, Eklund PC, Yun JK, Kester M, Adair JH. Encapsulation of organic molecules in calcium phosphate nanocomposite particles for intracellular imaging and drug delivery. Nano Lett. 2008 Dec; 8(12):4108-15.
|
|
|
|
|
11.
|
Zhang R, Shah MV, Yang J, Nyland SB, Liu X, Yun JK, Albert R, Loughran TP. Network model of survival signaling in large granular lymphocyte leukemia. Proc Natl Acad Sci U S A. 2008 Oct 21; 105(42):16308-13.
|
|
|
|
|
12.
|
Bayerl MG, Bruggeman RD, Conroy EJ, Hengst JA, King TS, Jimenez M, Claxton DF, Yun JK. Sphingosine kinase 1 protein and mRNA are overexpressed in non-Hodgkin lymphomas and are attractive targets for novel pharmacological interventions. Leuk Lymphoma. 2008 May; 49(5):948-54.
|
|
|
|
|
13.
|
Itagaki K, Yun JK, Hengst JA, Yatani A, Hauser CJ, Spolarics Z, Deitch EA. Sphingosine 1-phosphate has dual functions in the regulation of endothelial cell permeability and Ca2+ metabolism. J Pharmacol Exp Ther. 2007 Oct; 323(1):186-91.
|
|
|
|
|
14.
|
Francy JM, Nag A, Conroy EJ, Hengst JA, Yun JK. Sphingosine kinase 1 expression is regulated by signaling through PI3K, AKT2, and mTOR in human coronary artery smooth muscle cells. Biochim Biophys Acta. 2007 Apr; 1769(4):253-65.
|
|
|
|
|
15.
|
Fox TE, Houck KL, O'Neill SM, Nagarajan M, Stover TC, Pomianowski PT, Unal O, Yun JK, Naides SJ, Kester M. Ceramide recruits and activates protein kinase C zeta (PKC zeta) within structured membrane microdomains. J Biol Chem. 2007 Apr 27; 282(17):12450-7.
|
|
|
|
|
16.
|
French KJ, Upson JJ, Keller SN, Zhuang Y, Yun JK, Smith CD. Antitumor activity of sphingosine kinase inhibitors. J Pharmacol Exp Ther. 2006 Aug; 318(2):596-603.
|
|
|
|
|
17.
|
Reese BE, Krissinger D, Yun JK, Billingsley ML. Elucidation of stannin function using microarray analysis: implications for cell cycle control. Gene Expr. 2006; 13(1):41-52.
|
|
|
|
|
18.
|
Davidson CE, Reese BE, Billingsley ML, Yun JK. The protein stannin binds 14-3-3zeta and modulates mitogen-activated protein kinase signaling. Brain Res Mol Brain Res. 2005 Aug 18; 138(2):256-63.
|
|
|
|
|
19.
|
Lee C, Xu DZ, Feketeova E, Kannan KB, Yun JK, Deitch EA, Fekete Z, Livingston DH, Hauser CJ. Attenuation of shock-induced acute lung injury by sphingosine kinase inhibition. J Trauma. 2004 Nov; 57(5):955-60.
|
|
|
|
|
20.
|
Davidson CE, Reese BE, Billingsley ML, Yun JK. Stannin, a protein that localizes to the mitochondria and sensitizes NIH-3T3 cells to trimethyltin and dimethyltin toxicity. Mol Pharmacol. 2004 Oct; 66(4):855-63.
|
|
|
|
|
21.
|
French KJ, Schrecengost RS, Lee BD, Zhuang Y, Smith SN, Eberly JL, Yun JK, Smith CD. Discovery and evaluation of inhibitors of human sphingosine kinase. Cancer Res. 2003 Sep 15; 63(18):5962-9.
|
|
|
|
|
22.
|
Yun JK, Kester M. Regulatory role of sphingomyelin metabolites in hypoxia-induced vascular smooth muscle cell proliferation. Arch Biochem Biophys. 2002 Dec 1; 408(1):78-86.
|
|
|
|