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Gerson Rosenberg
Title Professor
Institution College of Medicine
Department Surgery
Address 500 University Drive Hershey PA 17033
Mailbox: H151
Telephone 7175316301
Email
Background
PREFERRED TITLE/ROLE:

Professor of Surgery, and Bioengineering

SECONDARY APPOINTMENT(S)/ INSTITUTE(S)/ CENTER(S):

Bioengineering

GRADUATE PROGRAM AFFILIATIONS:

Bioengineering

EDUCATION:

Ph.D., Pennsylvania State University, 1975

NARRATIVE:

The activities of the Division of Artificial Organs center largely around the development of mechanical left ventricular assist devices and artificial hearts. Emphasis is placed on interdisciplinary participation in research activities by members of the College of Medicine, the College of Engineering, and the Bioengineering Program. Penn State has developed a pneumatically powered left ventricular assist device that is now a commercial product, and has been utilized in over 4,000 patients. Penn State has also developed a pneumatically powered artificial heart that has been utilized in four patients at Penn State's University Hospital, The Milton S. Hershey Medical Center. The major focus is now directed on permanent completely implantable systems as well as short term support for pediatric patients.The Division developed the Arrow LionHerat LVAD, the worlds first completely implantable LVAD and the Penn State Electric Total Artificial Heart that was sold to AbioMed and is the Abiocor II. Both bench research and animal implantation studies are being performed. Opportunities are available for one and two year research fellowships for residents in General and Cardiothoracic Surgery and engineers seeking Master's and Ph.D. degrees. Research opportunities are also provided for medical students. Research is funded through the National Institutes of Health, through industrial funding, and through foundation and private support. Research activities are conducted at facilities in the Division of Artificial Organs in the Department of Surgery, College of Medicine.
Publications
1. Cooper TK, Griffith JW, Reibson J, Peterson R, Roush EP, Zhong Q, Weiss WJ, Rosenberg G. Antibiotic-associated eosinophilic and occlusive arteritis in calves complicating preclinical studies of left ventricular assist devices. Toxicol Pathol. 2013; 41(3):519-27.
  View in: PubMed
 
2. Cooper TK, Zhong Q, Nabity M, Rosenberg G, Weiss WJ. Use of urinary biomarkers of renal ischemia in a lamb preclinical left ventricular assist device model. Artif Organs. 2012 Sep; 36(9):820-4.
  View in: PubMed
 
3. Weiss WJ, Carney EL, Clark JB, Peterson R, Cooper TK, Nifong TP, Siedlecki CA, Hicks D, Doxtater B, Lukic B, Yeager E, Reibson J, Cysyk J, Rosenberg G, Pierce WS. Chronic in vivo testing of the Penn State infant ventricular assist device. ASAIO J. 2012 Jan-Feb; 58(1):65-72.
  View in: PubMed
 
4. Cysyk J, Jhun CS, Newswanger R, Weiss W, Rosenberg G. Rotary blood pump control using integrated inlet pressure sensor. Conf Proc IEEE Eng Med Biol Soc. 2011; 2011:373-6.
  View in: PubMed
 
5. Medvitz RB, Boger DA, Izraelev V, Rosenberg G, Paterson EG. Computational fluid dynamics design and analysis of a passively suspended Tesla pump left ventricular assist device. Artif Organs. 2011 May; 35(5):522-33.
  View in: PubMed
 
6. Fritz B, Cysyk J, Newswanger R, Weiss W, Rosenberg G. Development of an inlet pressure sensor for control in a left ventricular assist device. ASAIO J. 2010 May-Jun; 56(3):180-5.
  View in: PubMed
 
7. Izraelev V, Weiss WJ, Fritz B, Newswanger RK, Paterson EG, Snyder A, Medvitz RB, Cysyk J, Pae WE, Hicks D, Lukic B, Rosenberg G. A passively suspended Tesla pump left ventricular assist device. ASAIO J. 2009 Nov-Dec; 55(6):556-61.
  View in: PubMed
 
8. Undar A, Pauliks L, Clark JB, Zahn J, Rosenberg G, Kunselman AR, Sun Q, Pekkan K, Saliba K, Carney E, Thomas N, Freeman W, Vrana K, El-Banayosy A, Ural SH, Wilson R, Umstead TM, Floros J, Phelps DS, Weiss W, Snyder A, Yang S, Kimatian S, Cyran SE, Chinchilli VM, Guan Y, Rider A, Haines N, Rogerson A, Alkan-Bozkaya T, Akcevin A, Sun K, Wang S, Cun L, Myers JL. Penn State Hershey--center for pediatric cardiovascular research. Artif Organs. 2009 Nov; 33(11):883-7.
  View in: PubMed
 
9. Undar A, Ungerleider RM, Giacomuzzi C, Duncan BW, Rosenberg G, Pierce WS, Waldhausen JA, Myers JL. Fourth International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion. ASAIO J. 2008 Sep-Oct; 54(5):445-6.
  View in: PubMed
 
10. Connell JM, Khalapyan T, Myers JL, Rosenberg G, Weiss WJ. Anatomic fit assessment for the Penn State pediatric ventricular assist device. ASAIO J. 2007 Nov-Dec; 53(6):687-91.
  View in: PubMed
 
11. Lukic B, Zapanta CM, Khalapyan T, Connell J, Pae WE, Myers JL, Wilson RP, Undar A, Rosenberg G, Weiss WJ. The effect of left ventricular function and drive pressures on the filling and ejection of a pulsatile pediatric ventricular assist device in an acute animal model. ASAIO J. 2007 May-Jun; 53(3):379-84.
  View in: PubMed
 
12. Connell JM, Pae WE, Rosenberg G. Comparison of LionHeart LVAD-implanted calves based on renal infarctions. ASAIO J. 2007 Mar-Apr; 53(2):147-51.
  View in: PubMed
 
13. Connell JM, Khalapyan T, Al-Mondhiry HA, Wilson RP, Rosenberg G, Weiss WJ. Anticoagulation of juvenile sheep and goats with heparin, warfarin, and clopidogrel. ASAIO J. 2007 Mar-Apr; 53(2):229-37.
  View in: PubMed
 
14. Undar A, Ji B, Lukic B, Zapanta CM, Kunselman AR, Reibson JD, Weiss WJ, Rosenberg G, Myers JL. Quantification of perfusion modes in terms of surplus hemodynamic energy levels in a simulated pediatric CPB model. ASAIO J. 2006 Nov-Dec; 52(6):712-7.
  View in: PubMed
 
15. Undar A, Ji B, Lukic B, Zapanta CM, Kunselman AR, Reibson JD, Khalapyan T, Baer L, Weiss WJ, Rosenberg G, Myers JL. Comparison of hollow-fiber membrane oxygenators with different perfusion modes during normothermic and hypothermic CPB in a simulated neonatal model. Perfusion. 2006 Nov; 21(6):381-90.
  View in: PubMed
 
16. Yamanaka H, Rosenberg G, Weiss WJ, Snyder AJ, Zapanta CM, Siedlecki CA. Short-term in vivo studies of surface thrombosis in a left ventricular assist system. ASAIO J. 2006 May-Jun; 52(3):257-65.
  View in: PubMed
 
17. Zapanta CM, Griffith JW, Hess GD, Doxtater BJ, Khalapyan T, Pae WE, Rosenberg G. Microtextured materials for circulatory support devices: preliminary studies. ASAIO J. 2006 Jan-Feb; 52(1):17-23.
  View in: PubMed
 
18. Yamanaka H, Rosenberg G, Weiss WJ, Snyder AJ, Zapanta CM, Siedlecki CA. Multiscale analysis of surface thrombosis in vivo in a left ventricular assist system. ASAIO J. 2005 Sep-Oct; 51(5):567-77.
  View in: PubMed
 
19. Undar A, Rosenberg G, Myers JL. Major factors in the controversy of pulsatile versus nonpulsatile flow during acute and chronic cardiac support. ASAIO J. 2005 May-Jun; 51(3):173-5.
  View in: PubMed
 
20. Zapanta CM, Snyder AJ, Weiss WJ, Cleary TJ, Reibson JD, Rawhouser MA, Lewis JP, Pierce WS, Rosenberg G. Durability testing of a completely implantable electric total artificial heart. ASAIO J. 2005 May-Jun; 51(3):214-23.
  View in: PubMed
 
21. Undar A, Rosenberg G, Myers JL. Part 1: principles of research on pulsatile and nonpulsatile perfusion during chronic support. ASAIO J. 2005 May-Jun; 51(3):303-4; author reply 305-8.
  View in: PubMed
 
22. Undar A, Zapanta CM, Reibson JD, Souba M, Lukic B, Weiss WJ, Snyder AJ, Kunselman AR, Pierce WS, Rosenberg G, Myers JL. Precise quantification of pressure flow waveforms of a pulsatile ventricular assist device. ASAIO J. 2005 Jan-Feb; 51(1):56-9.
  View in: PubMed
 
23. Undar A, Rosenberg G, Myers JL. Impact of pulsatile flow on microcirculation. ASAIO J. 2004 Nov-Dec; 50(6):624-5.
  View in: PubMed
 
24. Undar A, Rosenberg G, Myers JL. How should investigators compare different perfusion modes or different types of pulsatile flow during chronic support? ASAIO J. 2004 Jul-Aug; 50(4):401-2.
  View in: PubMed
 
25. Donahue TL, Rosenberg G, Jacobs CR, Weiss WJ. Finite element analysis of stresses developed in blood sacs of a pusherplate blood pump. Comput Methods Biomech Biomed Engin. 2003 Feb; 6(1):7-15.
  View in: PubMed
 
26. Hoenicke EM, Strange RG, Weiss WJ, Snyder AJ, Rawhouser MA, Rosenberg G, Prophet GA, Pae WE, Sun BC, Pierce WS. Modifications in surgical implantation of the Penn State electric total artificial heart. Ann Thorac Surg. 2001 Mar; 71(3 Suppl):S150-5; discussion S183-4.
  View in: PubMed
 
27. Mehta SM, Pae WE, Rosenberg G, Snyder AJ, Weiss WJ, Lewis JP, Frank DJ, Thompson JJ, Pierce WS. The LionHeart LVD-2000: a completely implanted left ventricular assist device for chronic circulatory support. Ann Thorac Surg. 2001 Mar; 71(3 Suppl):S156-61; discussion S183-4.
  View in: PubMed
 
28. Speedling EJ, Nizza AA, Eichhorn S, Rosenberg G, Schnepf P. The consumer survey review process: a pathway to quality. Mt Sinai J Med. 1993 Oct; 60(5):399-404.
  View in: PubMed
 
29. al-Mondhiry H, Pae WE, Rosenberg G, Pierce WS. Hematologic and hemostatic complications associated with long-term use of total artificial heart: clinical and experimental observations. Artif Organs. 1992 Feb; 16(1):83-9.
  View in: PubMed
 
30. Pierce WS, Rosenberg G, Snyder AJ, Pae WE, Donachy JH, Waldhausen JA. An electric artificial heart for clinical use. Ann Surg. 1990 Sep; 212(3):339-43; discussion 343-4.
  View in: PubMed
 
31. Weiss WJ, Rosenberg G, Snyder AJ, Cleary TJ, Gaumond RP, Geselowitz DB, Pierce WS. Permanent circulatory support systems at the Pennsylvania State University. IEEE Trans Biomed Eng. 1990 Feb; 37(2):138-45.
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32. al-Mondhiry H, Pae W, Rosenberg G, Pierce W. Hematologic abnormalities and thromboembolic complications in calves implanted with pneumatic artificial hearts. Long-term studies and autopsy findings. ASAIO Trans. 1989 Jul-Sep; 35(3):238-41.
  View in: PubMed
 
33. Weiss WJ, Rosenberg G, Snyder AJ, Pae WE, Richenbacher WE, Pierce WS. In vivo performance of a transcutaneous energy transmission system with the Penn State motor driven ventricular assist device. ASAIO Trans. 1989 Jul-Sep; 35(3):284-8.
  View in: PubMed
 
34. Oaks TE, Pae WE, Rosenberg G, Pennock JL, Pierce WS. The use of a paracorporeal ventricular assist device as a bridge to cardiac transplantation. ASAIO Trans. 1987 Jul-Sep; 33(3):408-12.
  View in: PubMed
 
35. Pierce WS, Donachy JH, Landis DL, Brighton JA, Rosenberg G, Migliore JJ, Prophet GA, White WJ, Waldhausen JA. Prolonged mechanical support of the left ventricle. Circulation. 1978 Sep; 58(3 Pt 2):I133-46.
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Keyword
Last Name
Institution
    
 
 
 
Co-Authors  
Myers, John
Pae, Walter
Pierce, William
Undar, Akif
Weiss, William
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