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Jiafen Hu
Title Research Associate
Institution College of Medicine
Department Pathology
Division Gittlen Cancer Research Institute
Address 500 University Drive Hershey PA 17033
Mailbox: H059
Telephone 7175314700
Email
Background
PREFERRED TITLE/ROLE:

Research Associate, Jake Gittlen Cancer Research

EDUCATION:

Post-Doc. Hershey Medical Center, Pennsylvania State University
Ph.D. Chinese Academy of Sciences
M.S and B.S Wuhan University
Publications
1. Cladel NM, Budgeon LR, Hu J, Balogh KK, Christensen ND. Synonymous codon changes in the oncogenes of the cottontail rabbit papillomavirus lead to increased oncogenicity and immunogenicity of the virus. Virology. 2013 Apr 10; 438(2):70-83.
  View in: PubMed
 
2. Bounds CE, Hu J, Cladel NM, Balogh K, Christensen ND. Vaccine generated immunity targets an HPV16 E7 HLA-A2.1-restricted CD8(+) T cell epitope relocated to an early gene or a late gene of the cottontail rabbit papillomavirus (CRPV) genome in HLA-A2.1 transgenic rabbits. Vaccine. 2011 Feb 1; 29(6):1194-200.
  View in: PubMed
 
3. Hu J, Schell TD, Peng X, Cladel NM, Balogh KK, Christensen ND. Using HLA-A2.1 Transgenic Rabbit Model to Screen and Characterize New HLA-A2.1 Restricted Epitope DNA Vaccines. J Vaccines Vaccin. 2010 Aug 20; 1(1).
  View in: PubMed
 
4. Hu J, Cladel N, Balogh K, Christensen N. Mucosally delivered peptides prime strong immunity in HLA-A2.1 transgenic rabbits. Vaccine. 2010 May 7; 28(21):3706-13.
  View in: PubMed
 
5. Chentoufi AA, Dasgupta G, Christensen ND, Hu J, Choudhury ZS, Azeem A, Jester JV, Nesburn AB, Wechsler SL, BenMohamed L. A novel HLA (HLA-A*0201) transgenic rabbit model for preclinical evaluation of human CD8+ T cell epitope-based vaccines against ocular herpes. J Immunol. 2010 Mar 1; 184(5):2561-71.
  View in: PubMed
 
6. Cladel NM, Hu J, Balogh KK, Christensen ND. Differences in methodology, but not differences in viral strain, account for variable experimental outcomes in laboratories utilizing the cottontail rabbit papillomavirus model. J Virol Methods. 2010 Apr; 165(1):36-41.
  View in: PubMed
 
7. Hu J, Cladel NM, Budgeon L, Balogh KK, Christensen ND. Papillomavirus DNA complementation in vivo. Virus Res. 2009 Sep; 144(1-2):117-22.
  View in: PubMed
 
8. Cladel NM, Hu J, Balogh KK, Christensen ND. CRPV genomes with synonymous codon optimizations in the CRPV E7 gene show phenotypic differences in growth and altered immunity upon E7 vaccination. PLoS One. 2008; 3(8):e2947.
  View in: PubMed
 
9. Hu J, Cladel N, Peng X, Balogh K, Christensen ND. Protective immunity with an E1 multivalent epitope DNA vaccine against cottontail rabbit papillomavirus (CRPV) infection in an HLA-A2.1 transgenic rabbit model. Vaccine. 2008 Feb 6; 26(6):809-16.
  View in: PubMed
 
10. Cladel NM, Hu J, Balogh K, Mejia A, Christensen ND. Wounding prior to challenge substantially improves infectivity of cottontail rabbit papillomavirus and allows for standardization of infection. J Virol Methods. 2008 Mar; 148(1-2):34-9.
  View in: PubMed
 
11. Hu J, Budgeon LR, Cladel NM, Culp TD, Balogh KK, Christensen ND. Detection of L1, infectious virions and anti-L1 antibody in domestic rabbits infected with cottontail rabbit papillomavirus. J Gen Virol. 2007 Dec; 88(Pt 12):3286-93.
  View in: PubMed
 
12. Hu J, Peng X, Budgeon LR, Cladel NM, Balogh KK, Christensen ND. Establishment of a cottontail rabbit papillomavirus/HLA-A2.1 transgenic rabbit model. J Virol. 2007 Jul; 81(13):7171-7.
  View in: PubMed
 
13. Hu J, Cladel NM, Christensen ND. Increased immunity to cottontail rabbit papillomavirus infection in EIII/JC inbred rabbits after vaccination with a mutant E6 that correlates with spontaneous regression. Viral Immunol. 2007; 20(2):320-5.
  View in: PubMed
 
14. Hu J, Peng X, Schell TD, Budgeon LR, Cladel NM, Christensen ND. An HLA-A2.1-transgenic rabbit model to study immunity to papillomavirus infection. J Immunol. 2006 Dec 1; 177(11):8037-45.
  View in: PubMed
 
15. Hu J, Cladel NM, Balogh K, Budgeon L, Christensen ND. Impact of genetic changes to the CRPV genome and their application to the study of pathogenesis in vivo. Virology. 2007 Feb 20; 358(2):384-90.
  View in: PubMed
 
16. Hu J, Cladel NM, Budgeon LR, Reed CA, Pickel MD, Christensen ND. Protective cell-mediated immunity by DNA vaccination against Papillomavirus L1 capsid protein in the Cottontail Rabbit Papillomavirus model. Viral Immunol. 2006; 19(3):492-507.
  View in: PubMed
 
17. Hu J, Peng X, Cladel NM, Pickel MD, Christensen ND. Large cutaneous rabbit papillomas that persist during cyclosporin A treatment can regress spontaneously after cessation of immunosuppression. J Gen Virol. 2005 Jan; 86(Pt 1):55-63.
  View in: PubMed
 
18. Hu J, Cladel NM, Budgeon LR, Christensen ND. Characterization of three rabbit oral papillomavirus oncogenes. Virology. 2004 Jul 20; 325(1):48-55.
  View in: PubMed
 
19. Hu J, Cladel NM, Wang Z, Han R, Pickel MD, Christensen ND. GM-CSF enhances protective immunity to cottontail rabbit papillomavirus E8 genetic vaccination in rabbits. Vaccine. 2004 Mar 12; 22(9-10):1124-30.
  View in: PubMed
 
20. Hu J, Cladel NM, Pickel MD, Christensen ND. Amino acid residues in the carboxy-terminal region of cottontail rabbit papillomavirus E6 influence spontaneous regression of cutaneous papillomas. J Virol. 2002 Dec; 76(23):11801-8.
  View in: PubMed
 
21. Hu J, Han R, Cladel NM, Pickel MD, Christensen ND. Intracutaneous DNA vaccination with the E8 gene of cottontail rabbit papillomavirus induces protective immunity against virus challenge in rabbits. J Virol. 2002 Jul; 76(13):6453-9.
  View in: PubMed
 
 
Keyword
Last Name
Institution
    
 
 
 
Keywords   
Cottontail rabbit papillomavirus
Papillomavirus Infections
HLA-A2 Antigen
Vaccines, DNA
Rabbits
See all (114) keywords
Co-Authors  
Christensen, Neil
Peng, Xuwen
Schell, Todd
See all (3) people
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