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Elizabeth Frauenhoffer
Title Associate Professor
Institution College of Medicine
Department Pathology
Division Anatomic Pathology
Address 500 University Drive Hershey PA 17033
Telephone 7175318246
Email
Background
PREFERRED TITLE/ROLE:

Physician, Associate Professor of Pathology and Orthopaedics
Director, Bone and Soft Tissue Pathology Unit
Director of Undergraduate Pathology Education

EDUCATION:
B.A. cum laude, University of Pennsylvania (1979)
M.D., Medical College of Pennsylvania/Drexel University - School of Medicine (1983)
Residency, Pathology, Anatomic and Clinical, Penn State Milton S. Hershey Medical Center (1987)
Fellowship, Pathology, Gynecological/Surgical, Penn State Milton S. Hershey Medical Center (1988)
Fellowship, Pathology, Anatomic, University of Texas, M.D. Anderson Cancer Center (1989)

Diplomate, American Board of Pathology, Anatomic and Clinical Pathology, November 1987
Added Qualification in Cytopathology, May 1993

NARRATIVE:

Dr. Frauenhoffer has training and expertise in Orthopaedic Pathology, Gyynecologic Pathology and Cytopathology including Fine-needle Aspiration Biopsy. She also has interest in medical education and serves as the Director of Undergraduate Pathology Education, the Section Drector of the Histology Component of the Year I CMBMP course, the Co-Director of the Year II Musculoskeletal Course, and Director of the Year III-IV Selective in Pathology. She is one of the ombudspersons for medical and graduate students in the College of Medicine.

Publications
1. Kinney BJ, Hennrikus WL, Frauenhoffer EE. A 5-year-old girl with an enlarging mass at the elbow. J Pediatr Orthop B. 2012 Nov; 21(6):529-31.
  View in: PubMed
 
2. Smith A, Hal H, Frauenhoffer E. Extramedullary plasmacytoma of the pancreas: a rare entity. Case Rep Radiol. 2012; 2012:798264.
  View in: PubMed
 
3. Plakke MJ, Hennrikus WL, Frauenhoffer EE. Knee popping and clicking in a pediatric athlete: meniscal injury or sports tumor? J Surg Orthop Adv. 2012; 21(4):275-8.
  View in: PubMed
 
4. Fitzpatrick LR, Green C, Frauenhoffer EE, French KJ, Zhuang Y, Maines LW, Upson JJ, Paul E, Donahue H, Mosher TJ, Smith CD. Attenuation of arthritis in rodents by a novel orally-available inhibitor of sphingosine kinase. Inflammopharmacology. 2011 Apr; 19(2):75-87.
  View in: PubMed
 
5. Lucas KG, Shapiro T, Freiberg A, Frauenhoffer E. Matched unrelated umbilical cord blood transplantation for a patient with chemotherapy resistant Wilms tumor. Pediatr Blood Cancer. 2010 Oct; 55(4):763-5.
  View in: PubMed
 
6. Todd WU, Drabick JJ, Benninghoff MG, Frauenhoffer EE, Zander DS. Pulmonary crystal-storing histiocytosis diagnosed by computed tomography-guided fine-needle aspiration. Diagn Cytopathol. 2010 Apr; 38(4):274-8.
  View in: PubMed
 
7. Clarke LE, Frauenhoffer E, Fox E, Neves R, Bruggeman RD, Helm KF. CD10-positive myxofibrosarcomas: a pitfall in the differential diagnosis of atypical fibroxanthoma. J Cutan Pathol. 2010 Jul; 37(7):737-43.
  View in: PubMed
 
8. Ahmadpour N, Downey M, Frauenhoffer E, Riley T, Schreibman IR. Primary sclerosing cholangitis in association with multiple myeloma. Gastroenterol Hepatol (N Y). 2008 Aug; 4(8):580-3.
  View in: PubMed
 
9. Ruggiero FP, Frauenhoffer E, Stack BC. Thyroid lymphoma: a single institution's experience. Otolaryngol Head Neck Surg. 2005 Dec; 133(6):888-96.
  View in: PubMed
 
10. Ruggiero FP, Frauenhoffer EE, Stack BC. Papillary thyroid cancer with an initial presentation of abdominal and flank pain. Am J Otolaryngol. 2005 Mar-Apr; 26(2):142-5.
  View in: PubMed
 
11. Triano EA, Slusher LB, Atkins TA, Beneski JT, Gestl SA, Zolfaghari R, Polavarapu R, Frauenhoffer E, Weisz J. Class I alcohol dehydrogenase is highly expressed in normal human mammary epithelium but not in invasive breast cancer: implications for breast carcinogenesis. Cancer Res. 2003 Jun 15; 63(12):3092-100.
  View in: PubMed
 
12. Gestl SA, Green MD, Shearer DA, Frauenhoffer E, Tephly TR, Weisz J. Expression of UGT2B7, a UDP-glucuronosyltransferase implicated in the metabolism of 4-hydroxyestrone and all-trans retinoic acid, in normal human breast parenchyma and in invasive and in situ breast cancers. Am J Pathol. 2002 Apr; 160(4):1467-79.
  View in: PubMed
 
13. Grenko RT, Abendroth CS, Frauenhoffer EE, Ruggiero FM, Zaino RJ. Variance in the interpretation of cervical biopsy specimens obtained for atypical squamous cells of undetermined significance. Am J Clin Pathol. 2000 Nov; 114(5):735-40.
  View in: PubMed
 
14. Mayer TJ, Frauenhoffer EE, Meyers AC. Expression of epidermal growth factor and platelet-derived growth factor receptors during cervical carcinogenesis. In Vitro Cell Dev Biol Anim. 2000 Nov-Dec; 36(10):667-76.
  View in: PubMed
 
15. Segal LS, Berlin JM, Schneider DJ, Moulton MJ, Frauenhoffer EE. Chondronecrosis of the hip. The protective role of the ossific nucleus in an animal model. Clin Orthop Relat Res. 2000 Aug; (377):265-71.
  View in: PubMed
 
16. Frauenhoffer, EE. and Waltz, K. Malignant Granular Cell Tumor, in:. Cutaneous Oncology: Pathophysiology, Diagnosis, and Management, edited by Stanley Miller and Mary E. Maloney. 1998; 907-914.
 
17. Dye CE, FrauenhofferEE, Vrahas M. Osteonecrosis of the Femoral Head in Haemophiliacs: Not All Joint Disease is Haemophilic Arthropathy. Haemophilia. 1997; 3(2):111-117.
 
18. Salam MM, Frauenhoffer EE. Left atrial appendage rupture caused by a seat belt: a case report and review of the literature. J Trauma. 1996 Apr; 40(4):642-3.
  View in: PubMed
 
19. Manning EC, Belenko MI, Frauenhoffer EE, Ahsan N. Acute renal failure secondary to solid tumor renal metastases: case report and review of the literature. Am J Kidney Dis. 1996 Feb; 27(2):284-91.
  View in: PubMed
 
20. Batsakis JG, Ro JY, Frauenhoffer EE. Bacillary angiomatosis. Ann Otol Rhinol Laryngol. 1995 Aug; 104(8):668-72.
  View in: PubMed
 
21. Robertson JS, Frauenhoffer EE, Stryker J, Schaitkin B, Velkley DE, McGinn JD. Osteoradionecrosis of the hyoid induced by combined modality therapy for laryngeal carcinoma. Ear Nose Throat J. 1995 Aug; 74(8):578-81.
  View in: PubMed
 
22. Abendroth CS, Frauenhoffer EE. Nodular fasciitis of the parotid gland. Report of a case with presentation in an unusual location and cytologic differential diagnosis. Acta Cytol. 1995 May-Jun; 39(3):530-4.
  View in: PubMed
 
23. Frauenhoffer EE. The histologic features of musculoskeletal tumors. Radiol Clin North Am. 1993 Mar; 31(2):373-81.
  View in: PubMed
 
24. Wetzel FT, Wilson SC, Manale BL, Frauenhoffer EE. Neural compression due to osteochondral fragments. A report of two cases and review of the literature. Spine (Phila Pa 1976). 1992 Oct; 17(10):1259-64.
  View in: PubMed
 
25. Zaino RJ, Ward S, Delgado G, Bundy B, Gore H, Fetter G, Ganjei P, Frauenhoffer E. Histopathologic predictors of the behavior of surgically treated stage IB squamous cell carcinoma of the cervix. A Gynecologic Oncology Group study. Cancer. 1992 Apr 1; 69(7):1750-8.
  View in: PubMed
 
26. Giudici MA, Eggli KD, Moser RP, Roloff JS, Frauenhoffer EE, Kransdorf MJ. Case report 730. Malignant large cell lymphoma of tibial epiphysis. Skeletal Radiol. 1992; 21(4):260-5.
  View in: PubMed
 
27. Frauenhoffer EE, Ro JY, el-Naggar AK, Ordóñez NG, Ayala AG. Clear cell cribriform hyperplasia of the prostate. Immunohistochemical and DNA flow cytometric study. Am J Clin Pathol. 1991 Apr; 95(4):446-53.
  View in: PubMed
 
28. Coen P, Kulin H, Ballantine T, Zaino R, Frauenhoffer E, Boal D, Inkster S, Brodie A, Santen R. An aromatase-producing sex-cord tumor resulting in prepubertal gynecomastia. N Engl J Med. 1991 Jan 31; 324(5):317-22.
  View in: PubMed
 
29. Frauenhoffer EE, Ro JY, Silva EG, el-Naggar A. Well-differentiated serous ovarian carcinoma presenting as a breast mass: a case report and flow cytometric DNA study. Int J Gynecol Pathol. 1991; 10(1):79-87.
  View in: PubMed
 
30. Doud TM, Moser RP, Giudici MA, Frauenhoffer EE, Maurer RJ. Case report 704: Extraskeletal osteosarcoma of the thigh with several suspected skeletal metastases and extensive metastases to the chest. Skeletal Radiol. 1991; 20(8):628-32.
  View in: PubMed
 
31. Frauenhoffer EE, Zaino RJ, Wolff TV, Whitney CE. Value of endocervical curettage in the staging of endometrial carcinoma. Int J Gynecol Pathol. 1987; 6(3):195-202.
  View in: PubMed
 
32. Appelbaum PC, Jacobs MR, Palko WM, Frauenhoffer EE, Duffett A. Accuracy and reproducibility of the IDS rapID STR system for species identification of streptococci. J Clin Microbiol. 1986 May; 23(5):843-6.
  View in: PubMed
 
33. Towfighi J, Berlin CM, Ladda RL, Frauenhoffer EE, Lehman RA. Neuropathology of oral-facial-digital syndromes. Arch Pathol Lab Med. 1985 Jul; 109(7):642-6.
  View in: PubMed
 
 
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Co-Authors  
Abendroth, Catherine
Hennrikus, William
Kulin, Howard
Weisz, Judith
Zaino, Richard
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