|
1.
|
Ghai V, Sharma K, Abbi KK, Shimko S, Epner EM. Current approaches to epigenetic therapy for the treatment of mantle cell lymphoma. Adv Exp Med Biol. 2013; 779:257-66.
|
|
|
|
|
2.
|
Joshi M, Sheikh H, Abbi K, Long S, Sharma K, Tulchinsky M, Epner E. Marginal zone lymphoma: old, new, targeted, and epigenetic therapies. Ther Adv Hematol. 2012 Oct; 3(5):275-90.
|
|
|
|
|
3.
|
Abbi KK, Zhu J, Ehmann WC, Epner E, Carraher M, Mierski J, Talamo G, Lucas K, Rybka W, Claxton D. G-CSF mobilized vs conventional donor lymphocytes for therapy of relapse or incomplete engraftment after allogeneic hematopoietic transplantation. Bone Marrow Transplant. 2013 Mar; 48(3):357-62.
|
|
|
|
|
4.
|
Hasanali Z, Sharma K, Epner E. Flipping the cyclin D1 switch in mantle cell lymphoma. Best Pract Res Clin Haematol. 2012 Jun; 25(2):143-52.
|
|
|
|
|
5.
|
Spurgeon SE, Pindyck T, Okada C, Chen Y, Chen Z, Mater E, Abbi K, Epner EM. Cladribine plus rituximab is an effective therapy for newly diagnosed mantle cell lymphoma. Leuk Lymphoma. 2011 Aug; 52(8):1488-94.
|
|
|
|
|
6.
|
Talamo G, Farooq U, Zangari M, Liao J, Dolloff NG, Loughran TP, Epner E. Beyond the CRAB symptoms: a study of presenting clinical manifestations of multiple myeloma. Clin Lymphoma Myeloma Leuk. 2010 Dec; 10(6):464-8.
|
|
|
|
|
7.
|
Fowler CJ, Dunlap J, Troyer D, Stenzel P, Epner E, Maziarz RT. Life-threatening adenovirus infections in the setting of the immunocompromised allogeneic stem cell transplant patients. Adv Hematol. 2010; 2010:601548.
|
|
|
|
|
8.
|
Spurgeon S, Yu M, Phillips JD, Epner EM. Cladribine: not just another purine analogue? Expert Opin Investig Drugs. 2009 Aug; 18(8):1169-81.
|
|
|
|
|
9.
|
Goy A, Bernstein SH, Kahl BS, Djulbegovic B, Robertson MJ, de Vos S, Epner E, Krishnan A, Leonard JP, Lonial S, Nasta S, O'Connor OA, Shi H, Boral AL, Fisher RI. Bortezomib in patients with relapsed or refractory mantle cell lymphoma: updated time-to-event analyses of the multicenter phase 2 PINNACLE study. Ann Oncol. 2009 Mar; 20(3):520-5.
|
|
|
|
|
10.
|
Liu H, Huang J, Wang J, Jiang S, Bailey AS, Goldman DC, Welcker M, Bedell V, Slovak ML, Clurman B, Thayer M, Fleming WH, Epner E. Transvection mediated by the translocated cyclin D1 locus in mantle cell lymphoma. J Exp Med. 2008 Aug 4; 205(8):1843-58.
|
|
|
|
|
11.
|
Laport GG, Sandmaier BM, Storer BE, Scott BL, Stuart MJ, Lange T, Maris MB, Agura ED, Chauncey TR, Wong RM, Forman SJ, Petersen FB, Wade JC, Epner E, Bruno B, Bethge WA, Curtin PT, Maloney DG, Blume KG, Storb RF. Reduced-intensity conditioning followed by allogeneic hematopoietic cell transplantation for adult patients with myelodysplastic syndrome and myeloproliferative disorders. Biol Blood Marrow Transplant. 2008 Feb; 14(2):246-55.
|
|
|
|
|
12.
|
Yu M, Epner E. The epigenetics of mantle cell lymphoma. Curr Treat Options Oncol. 2007 Oct; 8(5):375-81.
|
|
|
|
|
13.
|
Kahl C, Storer BE, Sandmaier BM, Mielcarek M, Maris MB, Blume KG, Niederwieser D, Chauncey TR, Forman SJ, Agura E, Leis JF, Bruno B, Langston A, Pulsipher MA, McSweeney PA, Wade JC, Epner E, Bo Petersen F, Bethge WA, Maloney DG, Storb R. Relapse risk in patients with malignant diseases given allogeneic hematopoietic cell transplantation after nonmyeloablative conditioning. Blood. 2007 Oct 1; 110(7):2744-8.
|
|
|
|
|
14.
|
Fisher RI, Bernstein SH, Kahl BS, Djulbegovic B, Robertson MJ, de Vos S, Epner E, Krishnan A, Leonard JP, Lonial S, Stadtmauer EA, O'Connor OA, Shi H, Boral AL, Goy A. Multicenter phase II study of bortezomib in patients with relapsed or refractory mantle cell lymphoma. J Clin Oncol. 2006 Oct 20; 24(30):4867-74.
|
|
|
|
|
15.
|
Yi Z, Cohen-Barak O, Hagiwara N, Kingsley PD, Fuchs DA, Erickson DT, Epner EM, Palis J, Brilliant MH. Sox6 directly silences epsilon globin expression in definitive erythropoiesis. PLoS Genet. 2006 Feb; 2(2):e14.
|
|
|
|
|
16.
|
Kerbauy FR, Storb R, Hegenbart U, Gooley T, Shizuru J, Al-Ali HK, Radich JP, Maloney DG, Agura E, Bruno B, Epner EM, Chauncey TR, Blume KG, Niederwieser D, Sandmaier BM. Hematopoietic cell transplantation from HLA-identical sibling donors after low-dose radiation-based conditioning for treatment of CML. Leukemia. 2005 Jun; 19(6):990-7.
|
|
|
|
|
17.
|
Wang J, Liu H, Lin CM, Aladjem MI, Epner EM. Targeted deletion of the chicken beta-globin regulatory elements reveals a cooperative gene silencing activity. J Biol Chem. 2005 Jun 17; 280(24):23340-8.
|
|
|
|
|
18.
|
Liu H, Wang J, Epner EM. Cyclin D1 activation in B-cell malignancy: association with changes in histone acetylation, DNA methylation, and RNA polymerase II binding to both promoter and distal sequences. Blood. 2004 Oct 15; 104(8):2505-13.
|
|
|
|
|
19.
|
Hegenbart U, Niederwieser D, Forman S, Holler E, Leiblein S, Johnston L, Pönisch W, Epner E, Witherspoon R, Blume K, Storb R. Hematopoietic cell transplantation from related and unrelated donors after minimal conditioning as a curative treatment modality for severe paroxysmal nocturnal hemoglobinuria. Biol Blood Marrow Transplant. 2003 Nov; 9(11):689-97.
|
|
|
|
|
20.
|
Aladjem MI, Rodewald LW, Lin CM, Bowman S, Cimbora DM, Brody LL, Epner EM, Groudine M, Wahl GM. Replication initiation patterns in the beta-globin loci of totipotent and differentiated murine cells: evidence for multiple initiation regions. Mol Cell Biol. 2002 Jan; 22(2):442-52.
|
|
|
|
|
21.
|
Cimbora DM, Schübeler D, Reik A, Hamilton J, Francastel C, Epner EM, Groudine M. Long-distance control of origin choice and replication timing in the human beta-globin locus are independent of the locus control region. Mol Cell Biol. 2000 Aug; 20(15):5581-91.
|
|
|
|
|
22.
|
Bender MA, Reik A, Close J, Telling A, Epner E, Fiering S, Hardison R, Groudine M. Description and targeted deletion of 5' hypersensitive site 5 and 6 of the mouse beta-globin locus control region. Blood. 1998 Dec 1; 92(11):4394-403.
|
|
|
|
|
23.
|
Reik A, Telling A, Zitnik G, Cimbora D, Epner E, Groudine M. The locus control region is necessary for gene expression in the human beta-globin locus but not the maintenance of an open chromatin structure in erythroid cells. Mol Cell Biol. 1998 Oct; 18(10):5992-6000.
|
|
|
|
|
24.
|
Epner E, Reik A, Cimbora D, Telling A, Bender MA, Fiering S, Enver T, Martin DI, Kennedy M, Keller G, Groudine M. The beta-globin LCR is not necessary for an open chromatin structure or developmentally regulated transcription of the native mouse beta-globin locus. Mol Cell. 1998 Oct; 2(4):447-55.
|
|
|
|
|
25.
|
Ley TJ, Hug B, Fiering S, Epner E, Bender MA, Groudine M. Reduced beta-globin gene expression in adult mice containing deletions of locus control region 5' HS-2 or 5' HS-3. Ann N Y Acad Sci. 1998 Jun 30; 850:45-53.
|
|
|
|
|
26.
|
Hug BA, Wesselschmidt RL, Fiering S, Bender MA, Epner E, Groudine M, Ley TJ. Analysis of mice containing a targeted deletion of beta-globin locus control region 5' hypersensitive site 3. Mol Cell Biol. 1996 Jun; 16(6):2906-12.
|
|
|
|
|
27.
|
Dieken ES, Epner EM, Fiering S, Fournier RE, Groudine M. Efficient modification of human chromosomal alleles using recombination-proficient chicken/human microcell hybrids. Nat Genet. 1996 Feb; 12(2):174-82.
|
|
|
|
|
28.
|
Aladjem MI, Groudine M, Brody LL, Dieken ES, Fournier RE, Wahl GM, Epner EM. Participation of the human beta-globin locus control region in initiation of DNA replication. Science. 1995 Nov 3; 270(5237):815-9.
|
|
|
|
|
29.
|
Fiering S, Epner E, Robinson K, Zhuang Y, Telling A, Hu M, Martin DI, Enver T, Ley TJ, Groudine M. Targeted deletion of 5'HS2 of the murine beta-globin LCR reveals that it is not essential for proper regulation of the beta-globin locus. Genes Dev. 1995 Sep 15; 9(18):2203-13.
|
|
|
|
|
30.
|
Fiering S, Kim CG, Epner EM, Groudine M. An "in-out" strategy using gene targeting and FLP recombinase for the functional dissection of complex DNA regulatory elements: analysis of the beta-globin locus control region. Proc Natl Acad Sci U S A. 1993 Sep 15; 90(18):8469-73.
|
|
|
|
|
31.
|
Kim CG, Epner EM, Forrester WC, Groudine M. Inactivation of the human beta-globin gene by targeted insertion into the beta-globin locus control region. Genes Dev. 1992 Jun; 6(6):928-38.
|
|
|
|
|
32.
|
Epner E, Kim CG, Groudine M. What does the locus control region control? Curr Biol. 1992 May; 2(5):262-4.
|
|
|
|
|
33.
|
Forrester WC, Epner E, Driscoll MC, Enver T, Brice M, Papayannopoulou T, Groudine M. A deletion of the human beta-globin locus activation region causes a major alteration in chromatin structure and replication across the entire beta-globin locus. Genes Dev. 1990 Oct; 4(10):1637-49.
|
|
|
|
|
34.
|
Groudine M, Forrester WC, Novak U, Epner E. Replication and activation of the human beta-globin gene domain. Prog Clin Biol Res. 1989; 316A:15-35.
|
|
|
|
|
35.
|
Epner E, Forrester WC, Groudine M. Asynchronous DNA replication within the human beta-globin gene locus. Proc Natl Acad Sci U S A. 1988 Nov; 85(21):8081-5.
|
|
|
|
|
36.
|
Marks PA, Rifkind RA, Gambari R, Epner E, Chen ZX, Banks J. Commitment to terminal differentiation and the cell cycle. Curr Top Cell Regul. 1982; 21:189-203.
|
|
|
|
|
37.
|
Rifkind RA, Epner E, Marks PA. Commitment, DNA synthesis and gene expression in erythroleukemia cells. Adv Exp Med Biol. 1982; 158:253-7.
|
|
|
|
|
38.
|
Epner E, Rifkind RA, Marks PA. Replication of alpha and beta globin DNA sequences occurs during early S phase in murine erythroleukemia cells. Proc Natl Acad Sci U S A. 1981 May; 78(5):3058-62.
|
|
|
|
|
39.
|
Terada M, Epner E, Nudel U, Salmon J, Fibach E, Rifkind RA, Marks PA. Induction of murine erythroleukemia differentiation by actinomycin D. Proc Natl Acad Sci U S A. 1978 Jun; 75(6):2795-9.
|
|
|
|
|
40.
|
Marks PA, Reuben R, Epner E, Breslow R, Cobb W, Bogden AE, Rifkind RA. Induction of murine erythroleukemia cells to differentiate: a model for the detection of new anti-tumor drugs. Antibiot Chemother. 1978; 23:33-41.
|
|
|
|
|
41.
|
Firshein W, Meyer B, Epner E, Viggiani J. Role of polyadenylic acid in a deoxyribonucleic acid-membrane fraction extracted from pneumococci. J Bacteriol. 1976 Jul; 127(1):14-23.
|
|
|
|