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Edward Vresilovic
Title Professor
Institution College of Medicine
Department Orthopaedics and Rehabilitation
Division Orthopaedics
Address 500 University Drive Hershey PA 17033
Telephone 7175314837
Email
Background
PREFERRED TITLE/ROLE:

Physician

EDUCATION:

Fellowship, Joint Replacement, Thomas Jefferson University Hospital (1991)
Residency, Orthopedic Surgery, Hospital of the University of Pennsylvania (1990)
Internship, Surgery, General, Hospital of the University of Pennsylvania (1986)
M.D., University of Pennsylvania School of Medicine (1985)
Publications
1. Jacobs NT, Cortes DH, Vresilovic EJ, Elliott DM. Biaxial tension of fibrous tissue: using finite element methods to address experimental challenges arising from boundary conditions and anisotropy. J Biomech Eng. 2013 Feb; 135(2):021004.
  View in: PubMed
 
2. Showalter BL, Beckstein JC, Martin JT, Beattie EE, Espinoza OrĂ­as AA, Schaer TP, Vresilovic EJ, Elliott DM. Comparison of animal discs used in disc research to human lumbar disc: torsion mechanics and collagen content. Spine (Phila Pa 1976). 2012 Jul 1; 37(15):E900-7.
  View in: PubMed
 
3. Shapiro IM, Vresilovic EJ, Risbud MV. Is the spinal motion segment a diarthrodial polyaxial joint: what a nice nucleus like you doing in a joint like this? Bone. 2012 Mar; 50(3):771-6.
  View in: PubMed
 
4. O'Connell GD, Malhotra NR, Vresilovic EJ, Elliott DM. The effect of nucleotomy and the dependence of degeneration of human intervertebral disc strain in axial compression. Spine (Phila Pa 1976). 2011 Oct 1; 36(21):1765-71.
  View in: PubMed
 
5. Massey CJ, van Donkelaar CC, Vresilovic E, Zavaliangos A, Marcolongo M. Effects of aging and degeneration on the human intervertebral disc during the diurnal cycle: a finite element study. J Orthop Res. 2012 Jan; 30(1):122-8.
  View in: PubMed
 
6. O'Connell GD, Jacobs NT, Sen S, Vresilovic EJ, Elliott DM. Axial creep loading and unloaded recovery of the human intervertebral disc and the effect of degeneration. J Mech Behav Biomed Mater. 2011 Oct; 4(7):933-42.
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7. O'Connell GD, Vresilovic EJ, Elliott DM. Human intervertebral disc internal strain in compression: the effect of disc region, loading position, and degeneration. J Orthop Res. 2011 Apr; 29(4):547-55.
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8. Arthur A, Cannella M, Keane M, Singhatat W, Vresilovic E, Marcolongo M. Fill of the nucleus cavity affects mechanical stability in compression, bending, and torsion of a spine segment, which has undergone nucleus replacement. Spine (Phila Pa 1976). 2010 May 15; 35(11):1128-35.
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9. Joshi A, Massey CJ, Karduna A, Vresilovic E, Marcolongo M. The effect of nucleus implant parameters on the compressive mechanics of the lumbar intervertebral disc: a finite element study. J Biomed Mater Res B Appl Biomater. 2009 Aug; 90(2):596-607.
  View in: PubMed
 
10. Matz PG, Anderson PA, Kaiser MG, Holly LT, Groff MW, Heary RF, Mummaneni PV, Ryken TC, Choudhri TF, Vresilovic EJ, Resnick DK. Introduction and methodology: guidelines for the surgical management of cervical degenerative disease. J Neurosurg Spine. 2009 Aug; 11(2):101-3.
  View in: PubMed
 
11. Matz PG, Anderson PA, Holly LT, Groff MW, Heary RF, Kaiser MG, Mummaneni PV, Ryken TC, Choudhri TF, Vresilovic EJ, Resnick DK. The natural history of cervical spondylotic myelopathy. J Neurosurg Spine. 2009 Aug; 11(2):104-11.
  View in: PubMed
 
12. Holly LT, Matz PG, Anderson PA, Groff MW, Heary RF, Kaiser MG, Mummaneni PV, Ryken TC, Choudhri TF, Vresilovic EJ, Resnick DK. Clinical prognostic indicators of surgical outcome in cervical spondylotic myelopathy. J Neurosurg Spine. 2009 Aug; 11(2):112-8.
  View in: PubMed
 
13. Mummaneni PV, Kaiser MG, Matz PG, Anderson PA, Groff M, Heary R, Holly L, Ryken T, Choudhri T, Vresilovic E, Resnick D. Preoperative patient selection with magnetic resonance imaging, computed tomography, and electroencephalography: does the test predict outcome after cervical surgery? J Neurosurg Spine. 2009 Aug; 11(2):119-29.
  View in: PubMed
 
14. Mummaneni PV, Kaiser MG, Matz PG, Anderson PA, Groff MW, Heary RF, Holly LT, Ryken TC, Choudhri TF, Vresilovic EJ, Resnick DK. Cervical surgical techniques for the treatment of cervical spondylotic myelopathy. J Neurosurg Spine. 2009 Aug; 11(2):130-41.
  View in: PubMed
 
15. Ryken TC, Heary RF, Matz PG, Anderson PA, Groff MW, Holly LT, Kaiser MG, Mummaneni PV, Choudhri TF, Vresilovic EJ, Resnick DK. Cervical laminectomy for the treatment of cervical degenerative myelopathy. J Neurosurg Spine. 2009 Aug; 11(2):142-9.
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16. Anderson PA, Matz PG, Groff MW, Heary RF, Holly LT, Kaiser MG, Mummaneni PV, Ryken TC, Choudhri TF, Vresilovic EJ, Resnick DK. Laminectomy and fusion for the treatment of cervical degenerative myelopathy. J Neurosurg Spine. 2009 Aug; 11(2):150-6.
  View in: PubMed
 
17. Matz PG, Anderson PA, Groff MW, Heary RF, Holly LT, Kaiser MG, Mummaneni PV, Ryken TC, Choudhri TF, Vresilovic EJ, Resnick DK. Cervical laminoplasty for the treatment of cervical degenerative myelopathy. J Neurosurg Spine. 2009 Aug; 11(2):157-69.
  View in: PubMed
 
18. Matz PG, Holly LT, Mummaneni PV, Anderson PA, Groff MW, Heary RF, Kaiser MG, Ryken TC, Choudhri TF, Vresilovic EJ, Resnick DK. Anterior cervical surgery for the treatment of cervical degenerative myelopathy. J Neurosurg Spine. 2009 Aug; 11(2):170-3.
  View in: PubMed
 
19. Matz PG, Holly LT, Groff MW, Vresilovic EJ, Anderson PA, Heary RF, Kaiser MG, Mummaneni PV, Ryken TC, Choudhri TF, Resnick DK. Indications for anterior cervical decompression for the treatment of cervical degenerative radiculopathy. J Neurosurg Spine. 2009 Aug; 11(2):174-82.
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20. Matz PG, Ryken TC, Groff MW, Vresilovic EJ, Anderson PA, Heary RF, Holly LT, Kaiser MG, Mummaneni PV, Choudhri TF, Resnick DK. Techniques for anterior cervical decompression for radiculopathy. J Neurosurg Spine. 2009 Aug; 11(2):183-97.
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21. Heary RF, Ryken TC, Matz PG, Anderson PA, Groff MW, Holly LT, Kaiser MG, Mummaneni PV, Choudhri TF, Vresilovic EJ, Resnick DK. Cervical laminoforaminotomy for the treatment of cervical degenerative radiculopathy. J Neurosurg Spine. 2009 Aug; 11(2):198-202.
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22. Ryken TC, Heary RF, Matz PG, Anderson PA, Groff MW, Holly LT, Kaiser MG, Mummaneni PV, Choudhri TF, Vresilovic EJ, Resnick DK. Techniques for cervical interbody grafting. J Neurosurg Spine. 2009 Aug; 11(2):203-20.
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23. Kaiser MG, Mummaneni PV, Matz PG, Anderson PA, Groff MW, Heary RF, Holly LT, Ryken TC, Choudhri TF, Vresilovic EJ, Resnick DK. Radiographic assessment of cervical subaxial fusion. J Neurosurg Spine. 2009 Aug; 11(2):221-7.
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24. Kaiser MG, Mummaneni PV, Matz PG, Anderson PA, Groff MW, Heary RF, Holly LT, Ryken TC, Choudhri TF, Vresilovic EJ, Resnick DK. Management of anterior cervical pseudarthrosis. J Neurosurg Spine. 2009 Aug; 11(2):228-37.
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25. Holly LT, Matz PG, Anderson PA, Groff MW, Heary RF, Kaiser MG, Mummaneni PV, Ryken TC, Choudhri TF, Vresilovic EJ, Resnick DK. Functional outcomes assessment for cervical degenerative disease. J Neurosurg Spine. 2009 Aug; 11(2):238-44.
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26. Resnick DK, Anderson PA, Kaiser MG, Groff MW, Heary RF, Holly LT, Mummaneni PV, Ryken TC, Choudhri TF, Vresilovic EJ, Matz PG. Electrophysiological monitoring during surgery for cervical degenerative myelopathy and radiculopathy. J Neurosurg Spine. 2009 Aug; 11(2):245-52.
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27. Cannella M, Arthur A, Allen S, Keane M, Joshi A, Vresilovic E, Marcolongo M. The role of the nucleus pulposus in neutral zone human lumbar intervertebral disc mechanics. J Biomech. 2008 Jul 19; 41(10):2104-11.
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28. Nguyen AM, Johannessen W, Yoder JH, Wheaton AJ, Vresilovic EJ, Borthakur A, Elliott DM. Noninvasive quantification of human nucleus pulposus pressure with use of T1rho-weighted magnetic resonance imaging. J Bone Joint Surg Am. 2008 Apr; 90(4):796-802.
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29. Beckstein JC, Sen S, Schaer TP, Vresilovic EJ, Elliott DM. Comparison of animal discs used in disc research to human lumbar disc: axial compression mechanics and glycosaminoglycan content. Spine (Phila Pa 1976). 2008 Mar 15; 33(6):E166-73.
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30. Elliott DM, Yerramalli CS, Beckstein JC, Boxberger JI, Johannessen W, Vresilovic EJ. The effect of relative needle diameter in puncture and sham injection animal models of degeneration. Spine (Phila Pa 1976). 2008 Mar 15; 33(6):588-96.
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31. O'Connell GD, Johannessen W, Vresilovic EJ, Elliott DM. Human internal disc strains in axial compression measured noninvasively using magnetic resonance imaging. Spine (Phila Pa 1976). 2007 Dec 1; 32(25):2860-8.
  View in: PubMed
 
32. O'Connell GD, Vresilovic EJ, Elliott DM. Comparison of animals used in disc research to human lumbar disc geometry. Spine (Phila Pa 1976). 2007 Feb 1; 32(3):328-33.
  View in: PubMed
 
33. Vresilovic EJ, Johannessen W, Elliott DM. Disc mechanics with trans-endplate partial nucleotomy are not fully restored following cyclic compressive loading and unloaded recovery. J Biomech Eng. 2006 Dec; 128(6):823-9.
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34. Johannessen W, Cloyd JM, O'Connell GD, Vresilovic EJ, Elliott DM. Trans-endplate nucleotomy increases deformation and creep response in axial loading. Ann Biomed Eng. 2006 Apr; 34(4):687-96.
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35. Joshi A, Fussell G, Thomas J, Hsuan A, Lowman A, Karduna A, Vresilovic E, Marcolongo M. Functional compressive mechanics of a PVA/PVP nucleus pulposus replacement. Biomaterials. 2006 Jan; 27(2):176-84.
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36. Joshi A, Mehta S, Vresilovic E, Karduna A, Marcolongo M. Nucleus implant parameters significantly change the compressive stiffness of the human lumbar intervertebral disc. J Biomech Eng. 2005 Jun; 127(3):536-40.
  View in: PubMed
 
37. Vresilovic EJ, Mehta S, Placide R, Milam RA. Traumatic spondylopelvic dissociation. A report of two cases. J Bone Joint Surg Am. 2005 May; 87(5):1098-103.
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38. Risbud MV, Fertala J, Vresilovic EJ, Albert TJ, Shapiro IM. Nucleus pulposus cells upregulate PI3K/Akt and MEK/ERK signaling pathways under hypoxic conditions and resist apoptosis induced by serum withdrawal. Spine (Phila Pa 1976). 2005 Apr 15; 30(8):882-9.
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39. Radin S, El-Bassyouni G, Vresilovic EJ, Schepers E, Ducheyne P. In vivo tissue response to resorbable silica xerogels as controlled-release materials. Biomaterials. 2005 Mar; 26(9):1043-52.
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40. Risbud MV, Albert TJ, Guttapalli A, Vresilovic EJ, Hillibrand AS, Vaccaro AR, Shapiro IM. Differentiation of mesenchymal stem cells towards a nucleus pulposus-like phenotype in vitro: implications for cell-based transplantation therapy. Spine (Phila Pa 1976). 2004 Dec 1; 29(23):2627-32.
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41. Patel RV, DeLong W, Vresilovic EJ. Evaluation and treatment of spinal injuries in the patient with polytrauma. Clin Orthop Relat Res. 2004 May; (422):43-54.
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42. Johannessen W, Vresilovic EJ, Wright AC, Elliott DM. Intervertebral disc mechanics are restored following cyclic loading and unloaded recovery. Ann Biomed Eng. 2004 Jan; 32(1):70-6.
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43. Risbud MV, Izzo MW, Adams CS, Arnold WW, Hillibrand AS, Vresilovic EJ, Vaccaro AR, Albert TJ, Shapiro IM. An organ culture system for the study of the nucleus pulposus: description of the system and evaluation of the cells. Spine (Phila Pa 1976). 2003 Dec 15; 28(24):2652-8; discussion 2658-9.
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44. Gan JC, Ducheyne P, Vresilovic EJ, Swaim W, Shapiro IM. Intervertebral disc tissue engineering I: characterization of the nucleus pulposus. Clin Orthop Relat Res. 2003 Jun; (411):305-14.
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45. Gan JC, Ducheyne P, Vresilovic EJ, Shapiro IM. Intervertebral disc tissue engineering II: cultures of nucleus pulposus cells. Clin Orthop Relat Res. 2003 Jun; (411):315-24.
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46. Slipman CW, Shin CH, Patel RK, Isaac Z, Huston CW, Lipetz JS, Lenrow DA, Braverman DL, Vresilovic EJ. Etiologies of failed back surgery syndrome. Pain Med. 2002 Sep; 3(3):200-14; discussion 214-7.
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47. Slipman CW, Isaac Z, Lenrow DA, Chou LH, Gilchrist RV, Vresilovic EJ. Clinical evidence of chemical radiculopathy. Pain Physician. 2002 Jul; 5(3):260-5.
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48. Rajpurohit R, Risbud MV, Ducheyne P, Vresilovic EJ, Shapiro IM. Phenotypic characteristics of the nucleus pulposus: expression of hypoxia inducing factor-1, glucose transporter-1 and MMP-2. Cell Tissue Res. 2002 Jun; 308(3):401-7.
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49. Slipman CW, Rogers DP, Isaac Z, Lipetz JS, Herzog R, Lenrow DA, Vresilovic EJ. MR lumbar discography with intradiscal gadolinium in patients with severe anaphylactoid reaction to iodinated contrast material. Pain Med. 2002 Mar; 3(1):23-9.
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50. Slipman CW, Patel RK, Vresilovic EJ, Brautigam P, Mathies A, Adam LE, Lenrow D, Bhat AL, Isaac Z, Alavi A. Osseous stress reaction in a rower diagnosed with positron emission tomography (PET): a case report. Pain Physician. 2001 Oct; 4(4):336-42.
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51. Slipman CW, Lipetz JS, Plastaras CT, Jackson HB, Vresilovic EJ, Lenrow DA, Braverman DL. Fluoroscopically guided therapeutic sacroiliac joint injections for sacroiliac joint syndrome. Am J Phys Med Rehabil. 2001 Jun; 80(6):425-32.
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52. Slipman CW, Patel RK, Zhang L, Vresilovic E, Lenrow D, Shin C, Herzog R. Side of symptomatic annular tear and site of low back pain: is there a correlation? Spine (Phila Pa 1976). 2001 Apr 15; 26(8):E165-9.
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53. Slipman CW, Lipetz JS, Jackson HB, Plastaras CT, Vresilovic EJ. Outcomes of therapeutic selective nerve root blocks for whiplash induced cervical radicular pain. Pain Physician. 2001 Apr; 4(2):167-74.
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54. Slipman CW, Whyte Ii WS, Lichtenstein GR, Lenrow D, Braverman D, Ellen M, Vresilovic EJ. Thoracic spine spasms secondary to hemorrhagic intestinal ulcer. Pain Physician. 2001 Jan; 4(1):97-100.
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55. Gan JC, Ducheyne P, Vresilovic E, Shapiro IM. Bioactive glass serves as a substrate for maintenance of phenotype of nucleus pulposus cells of the intervertebral disc. J Biomed Mater Res. 2000 Sep 15; 51(4):596-604.
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56. Slipman CW, Lipetz JS, Herzog RJ, Vresilovic EJ. Nonsurgical treatment for radicular of pain of zygoapophyseal joint cyst origin: therapeutic selective nerve root block. Arch Phys Med Rehabil. 2000 Aug; 81(8):1119-22.
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57. Slipman CW, Lipetz JS, Jackson HB, Rogers DP, Vresilovic EJ. Therapeutic selective nerve root block in the nonsurgical treatment of atraumatic cervical spondylotic radicular pain: a retrospective analysis with independent clinical review. Arch Phys Med Rehabil. 2000 Jun; 81(6):741-6.
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58. Slipman CW, Jackson HB, Lipetz JS, Chan KT, Lenrow D, Vresilovic EJ. Sacroiliac joint pain referral zones. Arch Phys Med Rehabil. 2000 Mar; 81(3):334-8.
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59. Slipman CW, Lipetz JS, Jackson HB, Vresilovic EJ. Deep venous thrombosis and pulmonary embolism as a complication of bed rest for low back pain. Arch Phys Med Rehabil. 2000 Jan; 81(1):127-9.
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60. Katz MA, Beredjiklian PK, Vresilovic EJ, Tahernia AD, Gabriel JP, Chan PS, Heppenstall RB. Computed tomographic scanning of cervical spine fractures: does it influence treatment? J Orthop Trauma. 1999 Jun-Jul; 13(5):338-43.
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61. Luchetti WT, Copley LA, Vresilovic EJ, Black J, Steinberg ME. Drain entrapment and titanium to ceramic head deposition: two unique complications following closed reduction of a dislocated total hip arthroplasty. J Arthroplasty. 1998 Sep; 13(6):713-7.
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62. Slipman CW, Sterenfeld EB, Chou LH, Herzog R, Vresilovic E. The predictive value of provocative sacroiliac joint stress maneuvers in the diagnosis of sacroiliac joint syndrome. Arch Phys Med Rehabil. 1998 Mar; 79(3):288-92.
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63. Chan PS, Luchetti WT, Campbell JT, Vresilovic EJ. Supracondylar femur fracture above a mature knee fusion treated with a long locked intramedullary rod. Am J Orthop (Belle Mead NJ). 1997 Sep; 26(9):630-2.
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64. Slipman CW, Sterenfeld EB, Chou LH, Herzog R, Vresilovic E. The value of radionuclide imaging in the diagnosis of sacroiliac joint syndrome. Spine (Phila Pa 1976). 1996 Oct 1; 21(19):2251-4.
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65. Vresilovic EJ, Hozack WJ, Booth RE, Rothman RH. Comparative risk of early postoperative pulmonary embolism after cemented total knee versus total hip arthroplasty with low-dose warfarin prophylaxis. Am J Knee Surg. 1996; 9(1):2-6.
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66. Vresilovic EJ, Hozack WJ, Booth RE, Rothman RH. Incidence of pulmonary embolism after total knee arthroplasty with low-dose coumadin prophylaxis. Clin Orthop Relat Res. 1993 Jan; (286):27-31.
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67. Vresilovic EJ, Spindler KP, Robertson WW, Davidson RS, Drummond DS. Failures of pin removal after in situ pinning of slipped capital femoral epiphyses: a comparison of different pin types. J Pediatr Orthop. 1990 Nov-Dec; 10(6):764-8.
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Keyword
Last Name
Institution
    
 
 
 
Keywords   
Intervertebral Disc
Lumbar Vertebrae
Cervical Vertebrae
Radiculopathy
Spinal Cord Diseases
See all (269) keywords
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