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Herbert Y Reynolds
Title Professor Emeritus
Institution College of Medicine
Department Medicine
Address 500 University Drive, Hershey, PA 17033
Mailbox: H039
Telephone 7175315016
Fax 7175315831
Email
Other Positions
Title Professor Emeritus
Institution College of Medicine
Department Surgery
Background
PREFERRED TITLE/ROLE:

Professor Emeritus

EDUCATION:

M.D.
Publications
1. Reynolds HY. Re: Mentoring and coaching in medicine. Pharos Alpha Omega Alpha Honor Med Soc. 2012; 75(3):1p following 60.
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2. Reynolds HY. Review and perspective of the 12th Bronchoalveolar Lavage Conference within the second joint WASOG-BAL International Conference. Sarcoidosis Vasc Diffuse Lung Dis. 2011 Oct; 28(2):156-60.
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3. Reynolds HY. Bronchoalveolar lavage and other methods to define the human respiratory tract milieu in health and disease. Lung. 2011 Apr; 189(2):87-99.
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4. Castriotta RJ, Eldadah BA, Foster WM, Halter JB, Hazzard WR, Kiley JP, King TE, Horne FM, Nayfield SG, Reynolds HY, Schmader KE, Toews GB, High KP. Workshop on idiopathic pulmonary fibrosis in older adults. Chest. 2010 Sep; 138(3):693-703.
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5. Reynolds HY. Medical ear in the early morning tennis group--when to advise and what to say. Pharos Alpha Omega Alpha Honor Med Soc. 2010; 73(4):14-5; discussion 16.
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6. Reynolds HY. Free medical clinics: helping indigent patients and dealing with emerging health care needs. Acad Med. 2009 Oct; 84(10):1434-9.
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7. Choi AM, Reynolds HY, Colombini-Hatch S, Rothgeb A, Blaisdell CJ, Gail DB. NHLBI workshop: respiratory medicine-related research training for adult and pediatric fellows. Lung. 2009 Nov-Dec; 187(6):347-66.
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8. Reynolds HY. Present status of bronchoalveolar lavage in interstitial lung disease. Curr Opin Pulm Med. 2009 Sep; 15(5):479-85.
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9. Franks TJ, Colby TV, Travis WD, Tuder RM, Reynolds HY, Brody AR, Cardoso WV, Crystal RG, Drake CJ, Engelhardt J, Frid M, Herzog E, Mason R, Phan SH, Randell SH, Rose MC, Stevens T, Serge J, Sunday ME, Voynow JA, Weinstein BM, Whitsett J, Williams MC. Resident cellular components of the human lung: current knowledge and goals for research on cell phenotyping and function. Proc Am Thorac Soc. 2008 Sep 15; 5(7):763-6.
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10. Reynolds HY. Bronchoalveolar lavage: perspective from the 11th BAL conference. Monaldi Arch Chest Dis. 2008 Sep; 69(3):91-3.
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11. Reynolds HY. Bronchoalveolar lavage--obtaining biologic specimens from the respiratory tract surface. Sarcoidosis Vasc Diffuse Lung Dis. 2008 Sep; 25(1):5-9.
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12. Reynolds HY, Rothgeb A, Colombini-Hatch S, Gail DB, Kiley JP. The pipeline: preparing and training pulmonary scientists for research careers. Lung. 2008 Sep-Oct; 186(5):279-91.
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13. Reynolds HY. In choosing a research health career, mentoring is essential. Lung. 2008 Jan-Feb; 186(1):1-6.
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14. Reynolds HY. On becoming a doctor: a patient teaches. Acad Med. 2007 Sep; 82(9):875.
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15. Reynolds HY. Mentoring. Nurturing clinician and physician scientists in an academic career. Pharos Alpha Omega Alpha Honor Med Soc. 2007; 70(3):26-8.
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16. Reynolds HY. Medical volunteering: giving something back. Lung. 2006 Nov-Dec; 184(6):369-71.
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17. Reynolds H. The grey color of silver. Pharos Alpha Omega Alpha Honor Med Soc. 2006; 69(3):54.
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18. Wilkes DS, Egan TM, Reynolds HY. Lung transplantation: opportunities for research and clinical advancement. Am J Respir Crit Care Med. 2005 Oct 15; 172(8):944-55.
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19. Busse WW, Wanner A, Adams K, Reynolds HY, Castro M, Chowdhury B, Kraft M, Levine RJ, Peters SP, Sullivan EJ. Investigative bronchoprovocation and bronchoscopy in airway diseases. Am J Respir Crit Care Med. 2005 Oct 1; 172(7):807-16.
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20. Reid L, Meyrick B, Antony VB, Chang LY, Crapo JD, Reynolds HY. The mysterious pulmonary brush cell: a cell in search of a function. Am J Respir Crit Care Med. 2005 Jul 1; 172(1):136-9.
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21. Reynolds HY, Gail DB, Kiley JP. Interstitial lung diseases--where we started from and are now going. Sarcoidosis Vasc Diffuse Lung Dis. 2005 Mar; 22(1):5-12.
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22. Fink JN, Ortega HG, Reynolds HY, Cormier YF, Fan LL, Franks TJ, Kreiss K, Kunkel S, Lynch D, Quirce S, Rose C, Schleimer RP, Schuyler MR, Selman M, Trout D, Yoshizawa Y. Needs and opportunities for research in hypersensitivity pneumonitis. Am J Respir Crit Care Med. 2005 Apr 1; 171(7):792-8.
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23. Reynolds HY. Lung inflammation and fibrosis: an alveolar macrophage-centered perspective from the 1970s to 1980s. Am J Respir Crit Care Med. 2005 Jan 15; 171(2):98-102.
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24. Reynolds HY. Guidance for the doctor's physician child. Pharos Alpha Omega Alpha Honor Med Soc. 2004; 67(1):30-2.
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25. Reynolds HY. Anne L. Davis, M.D.: 1925-2003. Trans Am Clin Climatol Assoc. 2004; 115:xlix-li.
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26. Reynolds HY. President's address: R.T.H. Laënnec, M.D.--clinicopathologic observations, using the stethoscope, made chest medicine more scientific. Trans Am Clin Climatol Assoc. 2004; 115:1-29.
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27. Reynolds HY. Modulating airway defenses against microbes. Curr Opin Pulm Med. 2002 May; 8(3):154-65.
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28. Reynolds HY. Sarcoidosis: impact of other illnesses on the presentation and management of multi-organ disease. Lung. 2002; 180(5):281-99.
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29. Reynolds HY. Sampling local respiratory tract sites for inflammation. Sarcoidosis Vasc Diffuse Lung Dis. 2001 Jun; 18(2):138-48.
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30. Reynolds HY. Advances in understanding pulmonary host defense mechanisms: dendritic cell function and immunomodulation. Curr Opin Pulm Med. 2000 May; 6(3):209-16.
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31. Reynolds HY. Use of bronchoalveolar lavage in humans--past necessity and future imperative. Lung. 2000; 178(5):271-93.
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32. Reynolds HY. Defense mechanisms against infections. Curr Opin Pulm Med. 1999 May; 5(3):136-42.
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33. Reynolds HY. Diagnostic and management strategies for diffuse interstitial lung disease. Chest. 1998 Jan; 113(1):192-202.
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34. Reynolds HY. Respiratory infections: community-acquired pneumonia and newer microbes. Lung. 1996; 174(4):207-24.
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35. Reynolds HY. Pulmonary host defenses. Alcohol Clin Exp Res. 1995 Feb; 19(1):6-10.
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36. Reynolds HY. Respiratory host defenses--surface immunity. Immunobiology. 1994 Oct; 191(4-5):402-12.
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37. Gleeson K, Reynolds HY. Life-threatening pneumonia. Clin Chest Med. 1994 Sep; 15(3):581-602.
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38. Simons R, Reynolds H. New imperatives for internal medicine residency education. Am J Med. 1994 Mar; 96(3):I-IV.
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39. Bone CR, Higgins MW, Hurd SS, Reynolds HY. NHLBI workshop summary. Research needs and opportunities related to respiratory health of women. Am Rev Respir Dis. 1992 Aug; 146(2):528-35.
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40. Gleeson K, Reynolds HY. Pneumonia in the intensive care unit setting. J Intensive Care Med. 1992 Jan-Feb; 7(1):24-35.
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41. Reynolds HY. Immunologic system in the respiratory tract. Physiol Rev. 1991 Oct; 71(4):1117-33.
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42. Rankin JA, Huang SS, Sostman HD, Gee JB, Reynolds HY. An analysis of the inter-relationships among multiple bronchoalveolar lavage and serum determinations, physiologic tests, and clinical disease activity in patients with sarcoidosis. Sarcoidosis. 1991 Mar; 8(1):19-28.
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43. Simons RJ, Reynolds HY. Altered immune status in the elderly. Semin Respir Infect. 1990 Dec; 5(4):251-9.
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44. Reynolds HY. Selective samples from human airways can help in studying chronic bronchitis. J Lab Clin Med. 1990 Feb; 115(2):142-3.
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45. Sibille Y, Reynolds HY. Macrophages and polymorphonuclear neutrophils in lung defense and injury. Am Rev Respir Dis. 1990 Feb; 141(2):471-501.
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46. Reynolds HY, Huck JL. Immunologic responses in the lung. Respiration. 1990; 57(3):221-8.
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47. Marcy TW, Reynolds HY. Pulmonary consequences of congenital and acquired primary immunodeficiency states. Clin Chest Med. 1989 Dec; 10(4):503-19.
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48. Friedman LN, Filderman AE, D'Aquila TG, Reynolds HY. ELISA analysis of BACTEC bottles for the earlier diagnosis of tuberculosis. Am Rev Respir Dis. 1989 Sep; 140(3):668-71.
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49. Reynolds HY. Pulmonary sarcoidosis: do cellular and immunochemical lung parameters exist that would separate subgroups of patients for prognosis? Sarcoidosis. 1989 Mar; 6(1):1-4.
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50. Reynolds HY. Hypersensitivity pneumonitis: correlation of cellular and immunologic changes with clinical phases of disease. Lung. 1988; 166(4):189-208.
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51. Merrill W, Marcy TA, Reynolds HY. Bronchoalveolar lavage: clinical role and quantitative assessment. Respiration. 1988; 54 Suppl 1:3-8.
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52. Sibille Y, Naegel GP, Merrill WW, Young KR, Care SB, Reynolds HY. Neutrophil chemotactic activity produced by normal and activated human bronchoalveolar lavage cells. J Lab Clin Med. 1987 Nov; 110(5):624-33.
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53. Stoller JK, Rankin JA, Reynolds HY. The impact of bronchoalveolar lavage cell analysis on clinicians' diagnostic reasoning about interstitial lung disease. Chest. 1987 Nov; 92(5):839-43.
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54. Reynolds HY. Host defense impairments that may lead to respiratory infections. Clin Chest Med. 1987 Sep; 8(3):339-58.
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55. Marcy TW, Merrill WW, Rankin JA, Reynolds HY. Limitations of using urea to quantify epithelial lining fluid recovered by bronchoalveolar lavage. Am Rev Respir Dis. 1987 Jun; 135(6):1276-80.
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56. Reynolds HY. Bacterial adherence to respiratory tract mucosa--a dynamic interaction leading to colonization. Semin Respir Infect. 1987 Mar; 2(1):8-19.
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57. Reynolds HY. Bronchoalveolar lavage. Am Rev Respir Dis. 1987 Jan; 135(1):250-63.
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58. Cooper JA, Merrill WW, Reynolds HY. Cyclophosphamide modulation of bronchoalveolar cellular populations and macrophage oxidative metabolism. Possible mechanisms of pulmonary pharmacotoxicity. Am Rev Respir Dis. 1986 Jul; 134(1):108-14.
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59. Crystal RG, Reynolds HY, Kalica AR. Bronchoalveolar lavage. The report of an international conference. Chest. 1986 Jul; 90(1):122-31.
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60. Reynolds HY. Gram-negative bacillary pneumonia. Compr Ther. 1986 Apr; 12(4):22-30.
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61. Reynolds HY. Idiopathic interstitial pulmonary fibrosis. Contribution of bronchoalveolar lavage analysis. Chest. 1986 Mar; 89(3 Suppl):139S-144S.
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62. Rankin JA, Naegel GP, Reynolds HY. Use of a central laboratory for analysis of bronchoalveolar lavage fluid. Am Rev Respir Dis. 1986 Feb; 133(2):186-90.
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63. Reynolds HY. Louis E. Siltzbach Memorial Lecture. Concepts of pathogenesis and lung reactivity in hypersensitivity pneumonitis. Ann N Y Acad Sci. 1986; 465:287-303.
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64. Young KR, Rankin JA, Naegel GP, Paul ES, Reynolds HY. Bronchoalveolar lavage cells and proteins in patients with the acquired immunodeficiency syndrome. An immunologic analysis. Ann Intern Med. 1985 Oct; 103(4):522-33.
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65. Reynolds HY. Respiratory infections may reflect deficiencies in host defense mechanisms. Dis Mon. 1985 Feb; 31(2):1-98.
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66. Reynolds HY. Phagocytic defense in the lung. Antibiot Chemother. 1985; 36:74-87.
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67. Marcy TW, Reynolds HY. Pulmonary histiocytosis X. Lung. 1985; 163(3):129-50.
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68. Niederman MS, Merrill WW, Ferranti RD, Pagano KM, Palmer LB, Reynolds HY. Nutritional status and bacterial binding in the lower respiratory tract in patients with chronic tracheostomy. Ann Intern Med. 1984 Jun; 100(6):795-800.
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69. Naegel GP, Young KR, Reynolds HY. Receptors for human IgG subclasses on human alveolar macrophages. Am Rev Respir Dis. 1984 Mar; 129(3):413-8.
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70. Reynolds HY, Chrétien J. Respiratory tract fluids: analysis of content and contemporary use in understanding lung diseases. Dis Mon. 1984 Feb; 30(5):1-103.
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71. Niederman MS, Ferranti RD, Zeigler A, Merrill WW, Reynolds HY. Respiratory infection complicating long-term tracheostomy. The implication of persistent gram-negative tracheobronchial colonization. Chest. 1984 Jan; 85(1):39-44.
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72. Rankin JA, Naegel GP, Schrader CE, Matthay RA, Reynolds HY. Air-space immunoglobulin production and levels in bronchoalveolar lavage fluid of normal subjects and patients with sarcoidosis. Am Rev Respir Dis. 1983 Apr; 127(4):442-8.
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73. Reynolds HY. Lung inflammation: role of endogenous chemotactic factors in attracting polymorphonuclear granulocytes. Am Rev Respir Dis. 1983 Feb; 127(2):S16-25.
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74. Niederman MS, Rafferty TD, Sasaki CT, Merrill WW, Matthay RA, Reynolds HY. Comparison of bacterial adherence to ciliated and squamous epithelial cells obtained from the human respiratory tract. Am Rev Respir Dis. 1983 Jan; 127(1):85-90.
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75. Merrill WW, Reynolds HY. Bronchial lavage in inflammatory lung disease. Clin Chest Med. 1983 Jan; 4(1):71-84.
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76. Fick RB, Reynolds HY. Changing spectrum of pneumonia--news media creation or clinical reality? Am J Med. 1983 Jan; 74(1):1-8.
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77. Merrill W, O'Hearn E, Rankin J, Naegel G, Matthay RA, Reynolds HY. Kinetic analysis of respiratory tract proteins recovered during a sequential lavage protocol. Am Rev Respir Dis. 1982 Oct; 126(4):617-20.
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78. Reynolds HY. Hypersensitivity pneumonitis. Clin Chest Med. 1982 Sep; 3(3):503-19.
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79. Reynolds HY. Immunologic lung disease (part 2). Chest. 1982 Jun; 81(6):745-51.
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80. Reynolds HY. Immunologic lung diseases (part 1). Chest. 1982 May; 81(5):626-31.
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81. Reynolds HY. Could a defect in host-immunity be the cause of respiratory infections? Clin Chest Med. 1981 Jan; 2(1):103-10.
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82. Merrill WW, Naegel GP, Reynolds HY. Reaginic antibody in the lung lining fluid. Analysis of nomal human bronchoalveolar lavage fluid IgE and comparison to immunoglobulins G and A. J Lab Clin Med. 1980 Sep; 96(3):494-500.
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83. Merrill WW, Goodenberger D, Strober W, Matthay RA, Naegel GP, Reynolds HY. Free secretory component and other proteins in human lung lavage. Am Rev Respir Dis. 1980 Jul; 122(1):156-61.
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84. Reynolds HY. Immunologic concepts relating to the pathogenesis of diffuse interstitial lung diseases (emphasizing granulomatous forms and idiopathic pulmonary fibrosis). Trans Am Clin Climatol Assoc. 1980; 91:16-31.
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85. Gadek JE, Kelman JA, Fells G, Weinberger SE, Horwitz AL, Reynolds HY, Fulmer JD, Crystal RG. Collagenase in the lower respiratory tract of patients with idiopathic pulmonary fibrosis. N Engl J Med. 1979 Oct 4; 301(14):737-42.
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86. Reynolds HY. [Local pulmonary defenses and their amplification. Control mechanisms]. Nouv Presse Med. 1979 Jun 7; 8(25):2057-61.
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87. Merrill WW, Naegel GP, Matthay RA, Reynolds HY. Production of chemotactic factor(s) by in vivo cultured human alveolar macrophages. Chest. 1979 Feb; 75(2 Suppl):224.
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88. Reynolds HY. Lung host defenses: a status report. Chest. 1979 Feb; 75(2 Suppl):239-42.
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89. Weinberger SE, Kelman JA, Elson NA, Young RC, Reynolds HY, Fulmer JD, Crystal RG. Bronchoalveolar lavage in interstitial lung disease. Ann Intern Med. 1978 Oct; 89(4):459-66.
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90. Line BR, Fulmer JD, Reynolds HY, Roberts WC, Jones AE, Harris EK, Crystal RG. Gallium-67 citrate scanning in the staging of idiopathic pulmonary fibrosis: Correlation and physiologic and morphologic features and bronchoalveolar lavage. Am Rev Respir Dis. 1978 Aug; 118(2):355-65.
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91. Reynolds HY. The importance of lymphocytes in pulmonary health and disease. Lung. 1978; 155(3):225-42.
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92. Reynolds HY, Merrill WM, Amento EP, Naegel GP. Immunoglobulin A in secretions from the lower human respiratory tract. Adv Exp Med Biol. 1978; 107:553-64.
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93. Kazmierowski JA, Gallin JI, Reynolds HY. Mechanism for the inflammatory response in primate lungs. Demonstration and partial characterization of an alveolar macrophage-derived chemotactic factor with preferential activity for polymorphonuclear leukocytes. J Clin Invest. 1977 Feb; 59(2):273-81.
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94. Kazmierowski JA, Aduan RP, Reynolds HY. Pulmonary host defense: coordinated interaction of mechanical, cellular and humoral immune systems of the lung. Bull Eur Physiopathol Respir. 1977 Jan-Feb; 13(1):103-16.
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95. Reynolds HY, Fulmer JD, Kazmierowski JA, Roberts WC, Frank MM, Crystal RG. Analysis of cellular and protein content of broncho-alveolar lavage fluid from patients with idiopathic pulmonary fibrosis and chronic hypersensitivity pneumonitis. J Clin Invest. 1977 Jan; 59(1):165-75.
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96. Crystal RG, Fulmer JD, Roberts WC, Moss ML, Line BR, Reynolds HY. Idiopathic pulmonary fibrosis. Clinical, histologic, radiographic, physiologic, scintigraphic, cytologic, and biochemical aspects. Ann Intern Med. 1976 Dec; 85(6):769-88.
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97. Reynolds HY, Atkinson JP, Newball HH, Frank MM. Receptors for immunoglobulin and complement on human alveolar macrophages. J Immunol. 1975 Jun; 114(6):1813-9.
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98. Reynolds HY. Prevention and future control of hospital-associated infections commonly caused by gram-negative bacteria. Prev Med. 1974 Dec; 3(4):507-14.
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99. Reynolds HY. Pulmonary host defenses in rabbits after immunization with Pseudomonas antigens: the interaction of bacteria, antibodies, macrophages, and lymphocytes. J Infect Dis. 1974 Nov; 130 Suppl(0):S134-42.
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100. Reynolds HY, Newball HH. Analysis of proteins and respiratory cells obtained from human lungs by bronchial lavage. J Lab Clin Med. 1974 Oct; 84(4):559-73.
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101. Reynolds HY, Thompson RE. Pulmonary host defenses. I. Analysis of protein and lipids in bronchial secretions and antibody responses after vaccination with pseudomonas aeruginosa. J Immunol. 1973 Aug; 111(2):358-68.
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102. Reynolds HY, Thompson RE. Pulmonary host defenses. II. Interaction of respiratory antibodies with Pseudomonas aeruginosa and alveolar macrophages. J Immunol. 1973 Aug; 111(2):369-80.
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Co-Authors  
Gleeson, Kevin
Simons, Richard
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