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1.
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Hopper AK. Transfer RNA Post-Transcriptional Processing, Turnover, and Subcellular Dynamics in the Yeast Saccharomyces cerevisiae. Genetics. 2013 May; 194(1):43-67.
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2.
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Wu J, Huang HY, Hopper AK. A rapid and sensitive non-radioactive method applicable for genome-wide analysis of Saccharomyces cerevisiae genes involved in small RNA biology. Yeast. 2013 Apr; 30(4):119-28.
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3.
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Guy MP, Podyma BM, Preston MA, Shaheen HH, Krivos KL, Limbach PA, Hopper AK, Phizicky EM. Yeast Trm7 interacts with distinct proteins for critical modifications of the tRNAPhe anticodon loop. RNA. 2012 Oct; 18(10):1921-33.
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4.
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Dhungel N, Hopper AK. Beyond tRNA cleavage: novel essential function for yeast tRNA splicing endonuclease unrelated to tRNA processing. Genes Dev. 2012 Mar 1; 26(5):503-14.
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5.
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Karkusiewicz I, Turowski TW, Graczyk D, Towpik J, Dhungel N, Hopper AK, Boguta M. Maf1 protein, repressor of RNA polymerase III, indirectly affects tRNA processing. J Biol Chem. 2011 Nov 11; 286(45):39478-88.
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6.
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Cholbinski P, Jastrzebska Z, Wysocka-Kapcinska M, Plochocka D, Gornicka A, Hopper AK, Zoladek T. Yeast ubiquitin ligase Rsp5 contains nuclear localization and export signals. Eur J Cell Biol. 2011 Oct; 90(10):834-43.
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7.
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Rubio MA, Hopper AK. Transfer RNA travels from the cytoplasm to organelles. Wiley Interdiscip Rev RNA. 2011 Nov-Dec; 2(6):802-17.
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8.
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Hurto RL, Hopper AK. P-body components, Dhh1 and Pat1, are involved in tRNA nuclear-cytoplasmic dynamics. RNA. 2011 May; 17(5):912-24.
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9.
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Phizicky EM, Hopper AK. tRNA biology charges to the front. Genes Dev. 2010 Sep 1; 24(17):1832-60.
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10.
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Hopper AK, Pai DA, Engelke DR. Cellular dynamics of tRNAs and their genes. FEBS Lett. 2010 Jan 21; 584(2):310-7.
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11.
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Murthi A, Shaheen HH, Huang HY, Preston MA, Lai TP, Phizicky EM, Hopper AK. Regulation of tRNA bidirectional nuclear-cytoplasmic trafficking in Saccharomyces cerevisiae. Mol Biol Cell. 2010 Feb 15; 21(4):639-49.
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12.
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Lai TP, Stauffer KA, Murthi A, Shaheen HH, Peng G, Martin NC, Hopper AK. Mechanism and a peptide motif for targeting peripheral proteins to the yeast inner nuclear membrane. Traffic. 2009 Sep; 10(9):1243-56.
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13.
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Hopper AK, Shaheen HH. A decade of surprises for tRNA nuclear-cytoplasmic dynamics. Trends Cell Biol. 2008 Mar; 18(3):98-104.
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14.
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Weinert T, Hopper AK. tRNA traffic meets a cell-cycle checkpoint. Cell. 2007 Nov 30; 131(5):838-40.
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15.
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Shaheen HH, Horetsky RL, Kimball SR, Murthi A, Jefferson LS, Hopper AK. Retrograde nuclear accumulation of cytoplasmic tRNA in rat hepatoma cells in response to amino acid deprivation. Proc Natl Acad Sci U S A. 2007 May 22; 104(21):8845-50.
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16.
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Whitney ML, Hurto RL, Shaheen HH, Hopper AK. Rapid and reversible nuclear accumulation of cytoplasmic tRNA in response to nutrient availability. Mol Biol Cell. 2007 Jul; 18(7):2678-86.
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17.
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Hurto RL, Tong AH, Boone C, Hopper AK. Inorganic phosphate deprivation causes tRNA nuclear accumulation via retrograde transport in Saccharomyces cerevisiae. Genetics. 2007 Jun; 176(2):841-52.
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18.
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Butterfield-Gerson KL, Scheifele LZ, Ryan EP, Hopper AK, Parent LJ. Importin-beta family members mediate alpharetrovirus gag nuclear entry via interactions with matrix and nucleocapsid. J Virol. 2006 Feb; 80(4):1798-806.
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19.
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Hopper A. The 2006 George W. Beadle Medal. Fred Sherman. Genetics. 2006 Feb; 172(2):723-4.
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20.
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Engelke DR, Hopper AK. Modified view of tRNA: stability amid sequence diversity. Mol Cell. 2006 Jan 20; 21(2):144-5.
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21.
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Hopper AK. Cellular dynamics of small RNAs. Crit Rev Biochem Mol Biol. 2006 Jan-Feb; 41(1):3-19.
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22.
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Kwapisz M, Cholbinski P, Hopper AK, Rousset JP, Zoladek T. Rsp5 ubiquitin ligase modulates translation accuracy in yeast Saccharomyces cerevisiae. RNA. 2005 Nov; 11(11):1710-8.
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23.
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Gu W, Hurto RL, Hopper AK, Grayhack EJ, Phizicky EM. Depletion of Saccharomyces cerevisiae tRNA(His) guanylyltransferase Thg1p leads to uncharged tRNAHis with additional m(5)C. Mol Cell Biol. 2005 Sep; 25(18):8191-201.
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24.
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Shaheen HH, Hopper AK. Retrograde movement of tRNAs from the cytoplasm to the nucleus in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 2005 Aug 9; 102(32):11290-5.
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25.
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Murthi A, Hopper AK. Genome-wide screen for inner nuclear membrane protein targeting in Saccharomyces cerevisiae: roles for N-acetylation and an integral membrane protein. Genetics. 2005 Aug; 170(4):1553-60.
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26.
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Stanford DR, Whitney ML, Hurto RL, Eisaman DM, Shen WC, Hopper AK. Division of labor among the yeast Sol proteins implicated in tRNA nuclear export and carbohydrate metabolism. Genetics. 2004 Sep; 168(1):117-27.
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27.
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Hopper AK, Phizicky EM. tRNA transfers to the limelight. Genes Dev. 2003 Jan 15; 17(2):162-80.
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28.
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Kaminska J, Gajewska B, Hopper AK, Zoladek T. Rsp5p, a new link between the actin cytoskeleton and endocytosis in the yeast Saccharomyces cerevisiae. Mol Cell Biol. 2002 Oct; 22(20):6946-8.
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29.
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Feng W, Hopper AK. A Los1p-independent pathway for nuclear export of intronless tRNAs in Saccharomycescerevisiae. Proc Natl Acad Sci U S A. 2002 Apr 16; 99(8):5412-7.
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30.
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Pluta K, Lefebvre O, Martin NC, Smagowicz WJ, Stanford DR, Ellis SR, Hopper AK, Sentenac A, Boguta M. Maf1p, a negative effector of RNA polymerase III in Saccharomyces cerevisiae. Mol Cell Biol. 2001 Aug; 21(15):5031-40.
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31.
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Azad AK, Stanford DR, Sarkar S, Hopper AK. Role of nuclear pools of aminoacyl-tRNA synthetases in tRNA nuclear export. Mol Biol Cell. 2001 May; 12(5):1381-92.
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32.
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Gajewska B, Kaminska J, Jesionowska A, Martin NC, Hopper AK, Zoladek T. WW domains of Rsp5p define different functions: determination of roles in fluid phase and uracil permease endocytosis in Saccharomyces cerevisiae. Genetics. 2001 Jan; 157(1):91-101.
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33.
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Williams LR, Ellis SR, Hopper AK, Davis EO, Martin NC. Splicing before import - an intein in a mitochondrially targeted preprotein folds and is catalytically active in the cytoplasm in vivo. FEBS Lett. 2000 Jul 7; 476(3):301-5.
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34.
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Qiu H, Hu C, Anderson J, Björk GR, Sarkar S, Hopper AK, Hinnebusch AG. Defects in tRNA processing and nuclear export induce GCN4 translation independently of phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2. Mol Cell Biol. 2000 Apr; 20(7):2505-16.
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35.
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Stanford DR, Martin NC, Hopper AK. ADEPTs: information necessary for subcellular distribution of eukaryotic sorting isozymes resides in domains missing from eubacterial and archaeal counterparts. Nucleic Acids Res. 2000 Jan 15; 28(2):383-92.
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36.
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Benko AL, Vaduva G, Martin NC, Hopper AK. Competition between a sterol biosynthetic enzyme and tRNA modification in addition to changes in the protein synthesis machinery causes altered nonsense suppression. Proc Natl Acad Sci U S A. 2000 Jan 4; 97(1):61-6.
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37.
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Sarkar S, Azad AK, Hopper AK. Nuclear tRNA aminoacylation and its role in nuclear export of endogenous tRNAs in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 1999 Dec 7; 96(25):14366-71.
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38.
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Hopper AK. Nucleocytoplasmic transport: Inside out regulation. Curr Biol. 1999 Nov 4; 9(21):R803-6.
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39.
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Vaduva G, Martinez-Quiles N, Anton IM, Martin NC, Geha RS, Hopper AK, Ramesh N. The human WASP-interacting protein, WIP, activates the cell polarity pathway in yeast. J Biol Chem. 1999 Jun 11; 274(24):17103-8.
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40.
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Feng W, Benko AL, Lee JH, Stanford DR, Hopper AK. Antagonistic effects of NES and NLS motifs determine S. cerevisiae Rna1p subcellular distribution. J Cell Sci. 1999 Feb; 112 ( Pt 3):339-47.
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41.
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Tolerico LH, Benko AL, Aris JP, Stanford DR, Martin NC, Hopper AK. Saccharomyces cerevisiae Mod5p-II contains sequences antagonistic for nuclear and cytosolic locations. Genetics. 1999 Jan; 151(1):57-75.
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42.
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Hopper AK. Nuclear functions charge ahead. Science. 1998 Dec 11; 282(5396):2003-4.
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43.
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Sarkar S, Hopper AK. tRNA nuclear export in saccharomyces cerevisiae: in situ hybridization analysis. Mol Biol Cell. 1998 Nov; 9(11):3041-55.
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44.
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Vaduva G, Martin NC, Hopper AK. Actin-binding verprolin is a polarity development protein required for the morphogenesis and function of the yeast actin cytoskeleton. J Cell Biol. 1997 Dec 29; 139(7):1821-33.
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45.
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Zoladek T, Tobiasz A, Vaduva G, Boguta M, Martin NC, Hopper AK. MDP1, a Saccharomyces cerevisiae gene involved in mitochondrial/cytoplasmic protein distribution, is identical to the ubiquitin-protein ligase gene RSP5. Genetics. 1997 Mar; 145(3):595-603.
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46.
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Traglia HM, O'Connor JP, Tung KS, Dallabrida S, Shen WC, Hopper AK. Nucleus-associated pools of Rna1p, the Saccharomyces cerevisiae Ran/TC4 GTPse activating protein involved in nucleus/cytosol transit. Proc Natl Acad Sci U S A. 1996 Jul 23; 93(15):7667-72.
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47.
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Saavedra C, Tung KS, Amberg DC, Hopper AK, Cole CN. Regulation of mRNA export in response to stress in Saccharomyces cerevisiae. Genes Dev. 1996 Jul 1; 10(13):1608-20.
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48.
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Shen WC, Stanford DR, Hopper AK. Los1p, involved in yeast pre-tRNA splicing, positively regulates members of the SOL gene family. Genetics. 1996 Jun; 143(2):699-712.
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49.
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Wolfe CL, Hopper AK, Martin NC. Mechanisms leading to and the consequences of altering the normal distribution of ATP(CTP):tRNA nucleotidyltransferase in yeast. J Biol Chem. 1996 Mar 1; 271(9):4679-86.
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50.
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Zoladek T, Vaduva G, Hunter LA, Boguta M, Go BD, Martin NC, Hopper AK. Mutations altering the mitochondrial-cytoplasmic distribution of Mod5p implicate the actin cytoskeleton and mRNA 3' ends and/or protein synthesis in mitochondrial delivery. Mol Cell Biol. 1995 Dec; 15(12):6884-94.
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51.
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Corbett AH, Koepp DM, Schlenstedt G, Lee MS, Hopper AK, Silver PA. Rna1p, a Ran/TC4 GTPase activating protein, is required for nuclear import. J Cell Biol. 1995 Sep; 130(5):1017-26.
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52.
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Tung KS, Hopper AK. The glucose repression and RAS-cAMP signal transduction pathways of Saccharomyces cerevisiae each affect RNA processing and the synthesis of a reporter protein. Mol Gen Genet. 1995 Apr 10; 247(1):48-54.
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53.
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Rose AM, Belford HG, Shen WC, Greer CL, Hopper AK, Martin NC. Location of N2,N2-dimethylguanosine-specific tRNA methyltransferase. Biochimie. 1995; 77(1-2):45-53.
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54.
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Wolfe CL, Lou YC, Hopper AK, Martin NC. Interplay of heterogeneous transcriptional start sites and translational selection of AUGs dictate the production of mitochondrial and cytosolic/nuclear tRNA nucleotidyltransferase from the same gene in yeast. J Biol Chem. 1994 May 6; 269(18):13361-6.
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55.
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Hess SM, Stanford DR, Hopper AK. SRD1, a S. cerevisiae gene affecting pre-rRNA processing contains a C2/C2 zinc finger motif. Nucleic Acids Res. 1994 Apr 11; 22(7):1265-71.
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56.
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Boguta M, Hunter LA, Shen WC, Gillman EC, Martin NC, Hopper AK. Subcellular locations of MOD5 proteins: mapping of sequences sufficient for targeting to mitochondria and demonstration that mitochondrial and nuclear isoforms commingle in the cytosol. Mol Cell Biol. 1994 Apr; 14(4):2298-306.
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57.
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Murawski M, Szczesniak B, Zoladek T, Hopper AK, Martin NC, Boguta M. maf1 mutation alters the subcellular localization of the Mod5 protein in yeast. Acta Biochim Pol. 1994; 41(4):441-8.
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58.
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Martin NC, Hopper AK. How single genes provide tRNA processing enzymes to mitochondria, nuclei and the cytosol. Biochimie. 1994; 76(12):1161-7.
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59.
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Shen WC, Selvakumar D, Stanford DR, Hopper AK. The Saccharomyces cerevisiae LOS1 gene involved in pre-tRNA splicing encodes a nuclear protein that behaves as a component of the nuclear matrix. J Biol Chem. 1993 Sep 15; 268(26):19436-44.
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60.
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Rose AM, Joyce PB, Hopper AK, Martin NC. Separate information required for nuclear and subnuclear localization: additional complexity in localizing an enzyme shared by mitochondria and nuclei. Mol Cell Biol. 1992 Dec; 12(12):5652-8.
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61.
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Wang SS, Stanford DR, Silvers CD, Hopper AK. STP1, a gene involved in pre-tRNA processing, encodes a nuclear protein containing zinc finger motifs. Mol Cell Biol. 1992 Jun; 12(6):2633-43.
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62.
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Tung KS, Norbeck LL, Nolan SL, Atkinson NS, Hopper AK. SRN1, a yeast gene involved in RNA processing, is identical to HEX2/REG1, a negative regulator in glucose repression. Mol Cell Biol. 1992 Jun; 12(6):2673-80.
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63.
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Slusher LB, Gillman EC, Martin NC, Hopper AK. mRNA leader length and initiation codon context determine alternative AUG selection for the yeast gene MOD5. Proc Natl Acad Sci U S A. 1991 Nov 1; 88(21):9789-93.
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64.
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Gillman EC, Slusher LB, Martin NC, Hopper AK. MOD5 translation initiation sites determine N6-isopentenyladenosine modification of mitochondrial and cytoplasmic tRNA. Mol Cell Biol. 1991 May; 11(5):2382-90.
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65.
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Hopper AK, Traglia HM, Dunst RW. The yeast RNA1 gene product necessary for RNA processing is located in the cytosol and apparently excluded from the nucleus. J Cell Biol. 1990 Aug; 111(2):309-21.
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66.
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Fabian GR, Hess SM, Hopper AK. srd1, a Saccharomyces cerevisiae suppressor of the temperature-sensitive pre-rRNA processing defect of rrp1-1. Genetics. 1990 Mar; 124(3):497-504.
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67.
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Hopper AK. Genetic methods for study of trans-acting genes involved in processing of precursors to yeast cytoplasmic transfer RNAs. Methods Enzymol. 1990; 181:400-21.
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68.
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Li JM, Hopper AK, Martin NC. N2,N2-dimethylguanosine-specific tRNA methyltransferase contains both nuclear and mitochondrial targeting signals in Saccharomyces cerevisiae. J Cell Biol. 1989 Oct; 109(4 Pt 1):1411-9.
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69.
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Traglia HM, Atkinson NS, Hopper AK. Structural and functional analyses of Saccharomyces cerevisiae wild-type and mutant RNA1 genes. Mol Cell Biol. 1989 Jul; 9(7):2989-99.
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70.
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Ellis SR, Hopper AK, Martin NC. Amino-terminal extension generated from an upstream AUG codon increases the efficiency of mitochondrial import of yeast N2,N2-dimethylguanosine-specific tRNA methyltransferases. Mol Cell Biol. 1989 Apr; 9(4):1611-20.
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71.
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Wang SS, Hopper AK. Isolation of a yeast gene involved in species-specific pre-tRNA processing. Mol Cell Biol. 1988 Dec; 8(12):5140-9.
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72.
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Ellis SR, Hopper AK, Martin NC. Amino-terminal extension generated from an upstream AUG codon is not required for mitochondrial import of yeast N2,N2-dimethylguanosine-specific tRNA methyltransferase. Proc Natl Acad Sci U S A. 1987 Aug; 84(15):5172-6.
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73.
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Atkinson NS, Hopper AK. Chromosome specificity of polysomy promotion by disruptions of the Saccharomyces cerevisiae RNA1 gene. Genetics. 1987 Jul; 116(3):371-5.
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74.
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Fabian GR, Hopper AK. RRP1, a Saccharomyces cerevisiae gene affecting rRNA processing and production of mature ribosomal subunits. J Bacteriol. 1987 Apr; 169(4):1571-8.
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75.
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Hurt DJ, Wang SS, Lin YH, Hopper AK. Cloning and characterization of LOS1, a Saccharomyces cerevisiae gene that affects tRNA splicing. Mol Cell Biol. 1987 Mar; 7(3):1208-16.
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76.
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Dihanich ME, Najarian D, Clark R, Gillman EC, Martin NC, Hopper AK. Isolation and characterization of MOD5, a gene required for isopentenylation of cytoplasmic and mitochondrial tRNAs of Saccharomyces cerevisiae. Mol Cell Biol. 1987 Jan; 7(1):177-84.
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77.
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Najarian D, Dihanich ME, Martin NC, Hopper AK. DNA sequence and transcript mapping of MOD5: features of the 5' region which suggest two translational starts. Mol Cell Biol. 1987 Jan; 7(1):185-91.
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78.
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Ellis SR, Morales MJ, Li JM, Hopper AK, Martin NC. Isolation and characterization of the TRM1 locus, a gene essential for the N2,N2-dimethylguanosine modification of both mitochondrial and cytoplasmic tRNA in Saccharomyces cerevisiae. J Biol Chem. 1986 Jul 25; 261(21):9703-9.
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79.
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Atkinson NS, Dunst RW, Hopper AK. Characterization of an essential Saccharomyces cerevisiae gene related to RNA processing: cloning of RNA1 and generation of a new allele with a novel phenotype. Mol Cell Biol. 1985 May; 5(5):907-15.
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80.
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Martin NC, Hopper AK. Isopentenylation of both cytoplasmic and mitochondrial tRNA is affected by a single nuclear mutation. J Biol Chem. 1982 Sep 25; 257(18):10562-5.
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81.
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Hopper AK, Furukawa AH, Pham HD, Martin NC. Defects in modification of cytoplasmic and mitochondrial transfer RNAs are caused by single nuclear mutations. Cell. 1982 Mar; 28(3):543-50.
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82.
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Hopper AK, Kurjan J. tRNA synthesis: identification of in vivo precursor tRNAs from parental and mutant yeast strains. Nucleic Acids Res. 1981 Feb 25; 9(4):1019-29.
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83.
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Hopper AK, Schultz LD, Shapiro RA. Processing of intervening sequences: a new yeast mutant which fails to excise intervening sequences from precursor tRNAs. Cell. 1980 Mar; 19(3):741-51.
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84.
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Hopper AK, Banks F. A yeast mutant which accumulates precursor tRNAs. Cell. 1978 Jun; 14(2):211-9.
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85.
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Olson MV, Montgomery DL, Hopper AK, Page GS, Horodyski F, Hall BD. Molecular characterisation of the tyrosine tRNA genes of yeast. Nature. 1977 Jun 16; 267(5612):639-41.
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86.
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Andrew C, Hopper AK, Hall BD. A yeast mutant defective in the processing of 27S r-RNA precursor. Mol Gen Genet. 1976 Feb 27; 144(1):29-37.
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87.
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Hopper AK, Hall BD. Mating type and sporulation in yeast. I. Mutations which alter mating-type control over sporulation. Genetics. 1975 May; 80(1):41-59.
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88.
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Hopper AK, Kirsch J, Hall BD. Mating type and sporulation in yeast. II. Meiosis, recombination, and radiation sensitivity in an alpha-alpha diploid with altered sporulation control. Genetics. 1975 May; 80(1):61-76.
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89.
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Hopper AK, Hall BD. Mutation of a heterothallic strain to homothallism. Genetics. 1975 May; 80(1):77-85.
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90.
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Magee PT, Hopper AK. Protein synthesis in relation to sporulation and meiosis in yeast. J Bacteriol. 1974 Sep; 119(3):952-60.
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91.
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Hopper AK, Magee PT, Welch SK, Friedman M, Hall BD. Macromolecule synthesis and breakdown in relation to sporulation and meiosis in yeast. J Bacteriol. 1974 Aug; 119(2):619-28.
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