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1.
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Connelly TM, Koltun WA. The surgical treatment of inflammatory bowel disease-associated dysplasia. Expert Rev Gastroenterol Hepatol. 2013 May; 7(4):307-22.
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2.
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Connelly TM, Sehgal R, Berg AS, Hegarty JP, Deiling S, Stewart DB, Poritz LS, Koltun WA. Mutation in TAGAP is protective of anal sepsis in ileocolic Crohn's disease. Dis Colon Rectum. 2012 Nov; 55(11):1145-52.
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3.
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Connelly TM, Koltun WA. Less than total proctocolectomy in Crohn disease patients with dysplasia? Ann Surg. 2012 Aug; 256(2):227-8.
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4.
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Lin Z, Hegarty JP, Yu W, Cappel JA, Chen X, Faber PW, Wang Y, Poritz LS, Fan JB, Koltun WA. Identification of disease-associated DNA methylation in B cells from Crohn's disease and ulcerative colitis patients. Dig Dis Sci. 2012 Dec; 57(12):3145-53.
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5.
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Yu W, Lin Z, Hegarty JP, Chen X, Kelly AA, Wang Y, Poritz LS, Koltun WA. Genes differentially regulated by NKX2-3 in B cells between ulcerative colitis and Crohn's disease patients and possible involvement of EGR1. Inflammation. 2012 Jun; 35(3):889-99.
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6.
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Sehgal R, Berg A, Polinski JI, Hegarty JP, Lin Z, McKenna KJ, Stewart DB, Poritz LS, Koltun WA. Mutations in IRGM are associated with more frequent need for surgery in patients with ileocolonic Crohn's disease. Dis Colon Rectum. 2012 Feb; 55(2):115-21.
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7.
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Messaris E, Sehgal R, Deiling S, Koltun WA, Stewart D, McKenna K, Poritz LS. Dehydration is the most common indication for readmission after diverting ileostomy creation. Dis Colon Rectum. 2012 Feb; 55(2):175-80.
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8.
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Yu W, Hegarty JP, Berg A, Kelly AA, Wang Y, Poritz LS, Franke A, Schreiber S, Koltun WA, Lin Z. PTPN2 is associated with Crohn's disease and its expression is regulated by NKX2-3. Dis Markers. 2012; 32(2):83-91.
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9.
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Lin Z, Hegarty JP, Berb A, Wang Z, Kelly AA, Wang Y, Poritz LS, Wu R, Koltun WA. DLG5 P1371Q is associated with inflammatory bowel disease and complementary to R30Q in disease susceptibility. Swiss Med Wkly. 2011; 141:w13290.
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10.
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Poritz LS, Sehgal R, Hartnett K, Berg A, Koltun WA. Tumor volume and percent positive lymph nodes as a predictor of 5-year survival in colorectal cancer. Surgery. 2011 Oct; 150(4):649-55.
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11.
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Lin Z, John G, Hegarty JP, Berg A, Yu W, Wang Y, Kelly AA, Peterson BZ, Poritz LS, Floros J, Koltun WA. Genetic variants and monoallelic expression of surfactant protein-D in inflammatory bowel disease. Ann Hum Genet. 2011 Sep; 75(5):559-68.
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12.
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Poritz LS, Harris LR, Kelly AA, Koltun WA. Increase in the tight junction protein claudin-1 in intestinal inflammation. Dig Dis Sci. 2011 Oct; 56(10):2802-9.
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13.
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John G, Hegarty JP, Yu W, Berg A, Pastor DM, Kelly AA, Wang Y, Poritz LS, Schreiber S, Koltun WA, Lin Z. NKX2-3 variant rs11190140 is associated with IBD and alters binding of NFAT. Mol Genet Metab. 2011 Sep-Oct; 104(1-2):174-9.
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14.
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Yu W, Hegarty JP, Berg A, Chen X, West G, Kelly AA, Wang Y, Poritz LS, Koltun WA, Lin Z. NKX2-3 transcriptional regulation of endothelin-1 and VEGF signaling in human intestinal microvascular endothelial cells. PLoS One. 2011; 6(5):e20454.
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15.
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Lin Z, Hegarty JP, Lin T, Ostrov B, Wang Y, Yu W, Kelly AA, Poritz LS, Koltun WA. Failure of anakinra treatment of pyoderma gangrenosum in an IBD patient and relevance to the PSTPIP1 gene. Inflamm Bowel Dis. 2011 Jun; 17(6):E41-2.
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16.
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Haveran LA, Sehgal R, Poritz LS, McKenna KJ, Stewart DB, Koltun WA. Infliximab and/or azathioprine in the treatment of Crohn's disease-like complications after IPAA. Dis Colon Rectum. 2011 Jan; 54(1):15-20.
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17.
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Sehgal R, Berg A, Figueroa R, Poritz LS, McKenna KJ, Stewart DB, Koltun WA. Risk factors for surgical site infections after colorectal resection in diabetic patients. J Am Coll Surg. 2011 Jan; 212(1):29-34.
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18.
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Mukherjee A, McGarrity TJ, Ruggiero F, Koltun W, McKenna K, Poritz L, Baker MJ. The revised Bethesda guidelines: extent of utilization in a university hospital medical center with a cancer genetics program. Hered Cancer Clin Pract. 2010; 8:9.
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19.
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Sehgal R, Berg A, Hegarty JP, Kelly AA, Lin Z, Poritz LS, Koltun WA. NOD2/CARD15 mutations correlate with severe pouchitis after ileal pouch-anal anastomosis. Dis Colon Rectum. 2010 Nov; 53(11):1487-94.
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20.
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Lin Z, Hegarty JP, Cappel JA, Yu W, Chen X, Faber P, Wang Y, Kelly AA, Poritz LS, Peterson BZ, Schreiber S, Fan JB, Koltun WA. Identification of disease-associated DNA methylation in intestinal tissues from patients with inflammatory bowel disease. Clin Genet. 2011 Jul; 80(1):59-67.
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21.
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Wang Z, Liu T, Lin Z, Hegarty J, Koltun WA, Wu R. A general model for multilocus epistatic interactions in case-control studies. PLoS One. 2010; 5(8):e11384.
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22.
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Bennett-Guerrero E, Pappas TN, Koltun WA, Fleshman JW, Lin M, Garg J, Mark DB, Marcet JE, Remzi FH, George VV, Newland K, Corey GR. Gentamicin-collagen sponge for infection prophylaxis in colorectal surgery. N Engl J Med. 2010 Sep 9; 363(11):1038-49.
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23.
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Sehgal R, Koltun WA. Scoring systems in inflammatory bowel disease. Expert Rev Gastroenterol Hepatol. 2010 Aug; 4(4):513-21.
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24.
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Sehgal R, Koltun WA. Fibrin glue for the treatment of perineal fistulous Crohn's disease. Gastroenterology. 2010 Jun; 138(7):2216-9.
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25.
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Koltun WA. Long-term value of endoscopic dilatation for Crohn's strictures. Gut. 2010 Mar; 59(3):288.
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26.
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Fitzpatrick LR, Meirelles K, Small JS, Puleo FJ, Koltun WA, Cooney RN. A new model of chronic hapten-induced colitis in young rats. J Pediatr Gastroenterol Nutr. 2010 Mar; 50(3):240-50.
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27.
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Pastor DM, Poritz LS, Olson TL, Kline CL, Harris LR, Koltun WA, Chinchilli VM, Irby RB. Primary cell lines: false representation or model system? a comparison of four human colorectal tumors and their coordinately established cell lines. Int J Clin Exp Med. 2010; 3(1):69-83.
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28.
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Yu W, Lin Z, Pastor DM, Hegarty JP, Chen X, Kelly AA, Wang Y, Poritz LS, Koltun WA. Genes regulated by Nkx2-3 in sporadic and inflammatory bowel disease-associated colorectal cancer cell lines. Dig Dis Sci. 2010 Nov; 55(11):3171-80.
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29.
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Yu W, Lin Z, Hegarty JP, John G, Chen X, Faber PW, Kelly AA, Wang Y, Poritz LS, Schreiber S, Koltun WA. Genes regulated by Nkx2-3 in siRNA-mediated knockdown B cells: implication of endothelin-1 in inflammatory bowel disease. Mol Genet Metab. 2010 May; 100(1):88-95.
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30.
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Miller FA, Jones CR, Clarke LE, Lin Z, Adams DR, Koltun WA. Successful use of adalimumab in treating cutaneous metastatic Crohn's disease: report of a case. Inflamm Bowel Dis. 2009 Nov; 15(11):1611-2.
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31.
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Lin Z, Nelson L, Franke A, Poritz L, Li TY, Wu R, Wang Y, MacNeill C, Thomas NJ, Schreiber S, Koltun WA. OCTN1 variant L503F is associated with familial and sporadic inflammatory bowel disease. J Crohns Colitis. 2010 Jun; 4(2):132-8.
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32.
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Koltun WA. Role of medical rescue therapy in the management of acute severe ulcerative colitis: the surgical perspective. Expert Rev Gastroenterol Hepatol. 2009 Aug; 3(4):325-7.
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33.
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Yu W, Lin Z, Kelly AA, Hegarty JP, Poritz LS, Wang Y, Li T, Schreiber S, Koltun WA. Association of a Nkx2-3 polymorphism with Crohn's disease and expression of Nkx2-3 is up-regulated in B cell lines and intestinal tissues with Crohn's disease. J Crohns Colitis. 2009 Sep; 3(3):189-95.
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34.
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Burt CG, Cima RR, Koltun WA, Littlejohn CE, Ricciardi R, Temple LK, Rothenberger DA, Baxter NN. Developing a research agenda for the American Society of Colon and Rectal Surgeons: results of a delphi approach. Dis Colon Rectum. 2009 May; 52(5):898-905.
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35.
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Pastor DM, Pauli EM, Koltun WA, Haluck RS, Shope TR, Poritz LS. Parastomal hernia repair: a single center experience. JSLS. 2009 Apr-Jun; 13(2):170-5.
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36.
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Lin Z, Poritz L, Franke A, Li TY, Ruether A, Byrnes KA, Wang Y, Gebhard AW, MacNeill C, Thomas NJ, Schreiber S, Koltun WA. Genetic association of nonsynonymous variants of the IL23R with familial and sporadic inflammatory bowel disease in women. Dig Dis Sci. 2010 Mar; 55(3):739-46.
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37.
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Poritz LS, Zhang WJ, Thompson J, Boyer M, Clark C, Koltun WA. Impaired IL-4 phosphorylation of STAT6 in EBV transformed B-cells. J Surg Res. 2010 Aug; 162(2):290-8.
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38.
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Lin Z, Poritz L, Franke A, Li TY, Ruether A, Byrnes KA, Wang Y, Gebhard AW, MacNeill C, Thomas NJ, Wu R, Schreiber S, Koltun WA. Genetic association of DLG5 R30Q with familial and sporadic inflammatory bowel disease in men. Dis Markers. 2009; 27(5):193-201.
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39.
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Koltun WA. The future of surgical management of inflammatory bowel disease. Dis Colon Rectum. 2008 Jun; 51(6):813-7.
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40.
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Koltun WA. Endoscopic dilatation in Crohn's disease. Aliment Pharmacol Ther. 2008 May; 27(10):994-5; author reply 995.
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41.
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Cho CS, Dayton MT, Thompson JS, Koltun WA, Heise CP, Harms BA. Proctocolectomy-ileal pouch-anal anastomosis for ulcerative colitis after liver transplantation for primary sclerosing cholangitis: a multi-institutional analysis. J Gastrointest Surg. 2008 Jul; 12(7):1221-6.
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42.
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Zhang WJ, Li BH, Yang XZ, Li PD, Yuan Q, Liu XH, Xu SB, Zhang Y, Yuan J, Gerhard GS, Masker KK, Dong C, Koltun WA, Chorney MJ. IL-4-induced Stat6 activities affect apoptosis and gene expression in breast cancer cells. Cytokine. 2008 Apr; 42(1):39-47.
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43.
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Fitzpatrick LR, Small J, Hoerr RA, Bostwick EF, Maines L, Koltun WA. In vitro and in vivo effects of the probiotic Escherichia coli strain M-17: immunomodulation and attenuation of murine colitis. Br J Nutr. 2008 Sep; 100(3):530-41.
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44.
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Strong SA, Koltun WA, Hyman NH, Buie WD. Practice parameters for the surgical management of Crohn's disease. Dis Colon Rectum. 2007 Nov; 50(11):1735-46.
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45.
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Poritz LS, Lebo MA, Bobb AD, Ardell CM, Koltun WA. Management of peristomal pyoderma gangrenosum. J Am Coll Surg. 2008 Feb; 206(2):311-5.
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46.
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Fitzpatrick LR, Hertzog KL, Quatse AL, Koltun WA, Small JS, Vrana K. Effects of the probiotic formulation VSL#3 on colitis in weanling rats. J Pediatr Gastroenterol Nutr. 2007 May; 44(5):561-70.
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47.
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Poritz LS, Garver KI, Green C, Fitzpatrick L, Ruggiero F, Koltun WA. Loss of the tight junction protein ZO-1 in dextran sulfate sodium induced colitis. J Surg Res. 2007 Jun 1; 140(1):12-9.
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48.
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Fitzpatrick LR, Small JS, Poritz LS, McKenna KJ, Koltun WA. Enhanced intestinal expression of the proteasome subunit low molecular mass polypeptide 2 in patients with inflammatory bowel disease. Dis Colon Rectum. 2007 Mar; 50(3):337-48; discussion 348-50.
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49.
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Koltun WA. Dangers associated with endoscopic management of strictures in IBD. Inflamm Bowel Dis. 2007 Mar; 13(3):359-61; discussion 362-3.
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50.
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Poritz LS, Koltun WA. Percutaneous drainage and ileocolectomy for spontaneous intraabdominal abscess in Crohn's disease. J Gastrointest Surg. 2007 Feb; 11(2):204-8.
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51.
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Fitzpatrick LR, Khare V, Small JS, Koltun WA. Dextran sulfate sodium-induced colitis is associated with enhanced low molecular mass polypeptide 2 (LMP2) expression and is attenuated in LMP2 knockout mice. Dig Dis Sci. 2006 Jul; 51(7):1269-76.
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52.
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Cohen JL, Strong SA, Hyman NH, Buie WD, Dunn GD, Ko CY, Fleshner PR, Stahl TJ, Kim DG, Bastawrous AL, Perry WB, Cataldo PA, Rafferty JF, Ellis CN, Rakinic J, Gregorcyk S, Shellito PC, Kilkenny JW, Ternent CA, Koltun W, Tjandra JJ, Orsay CP, Whiteford MH, Penzer JR. Practice parameters for the surgical treatment of ulcerative colitis. Dis Colon Rectum. 2005 Nov; 48(11):1997-2009.
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53.
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Poritz LS, Rowe WA, Swenson BR, Hollenbeak CS, Koltun WA. Intravenous cyclosporine for the treatment of severe steroid refractory ulcerative colitis: what is the cost? Dis Colon Rectum. 2005 Sep; 48(9):1685-90.
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54.
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Swenson BR, Hollenbeak CS, Poritz LS, Koltun WA. Modified two-stage ileal pouch-anal anastomosis: equivalent outcomes with less resource utilization. Dis Colon Rectum. 2005 Feb; 48(2):256-61.
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55.
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Galka E, Thompson JL, Zhang WJ, Poritz LS, Koltun WA. Stat6(null phenotype) human lymphocytes exhibit increased apoptosis. J Surg Res. 2004 Nov; 122(1):14-20.
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56.
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Zhang WJ, Koltun WA, Thompson JL, Tilberg AF, Galka E, Poritz LS, Chorney MJ. Human B lymphoblast cell lines defective of Stat6 signaling produce high levels of proinflammatory cytokines IL-12, TNFalpha and IFNgamma. Int J Oncol. 2004 Feb; 24(2):447-53.
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57.
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Poritz LS, Garver KI, Tilberg AF, Koltun WA. Tumor necrosis factor alpha disrupts tight junction assembly. J Surg Res. 2004 Jan; 116(1):14-8.
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58.
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Zhang WJ, Thompson JL, Chorney MJ, Koltun WA. Phenotyping of IL4-induced nuclear Stat6 activity in humans: quantitation after gel shift assay using immortalized cell lines. Oncol Rep. 2003 Sep-Oct; 10(5):1281-8.
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59.
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Swenson BR, Hollenbeak CS, Koltun WA. Factors affecting cost and length of stay associated with the ileal pouch-anal anastomosis. Dis Colon Rectum. 2003 Jun; 46(6):754-61.
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60.
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Chun T, Page MJ, Gapin L, Matsuda JL, Xu H, Nguyen H, Kang HS, Stanic AK, Joyce S, Koltun WA, Chorney MJ, Kronenberg M, Wang CR. CD1d-expressing dendritic cells but not thymic epithelial cells can mediate negative selection of NKT cells. J Exp Med. 2003 Apr 7; 197(7):907-18.
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61.
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Zhang WJ, Koltun WA, Tilberg AF, Thompson JL, Chorney MJ. Genetic control of interleukin-4-induced activation of the human signal transducer and activator of transcription 6 signaling pathway. Hum Immunol. 2003 Apr; 64(4):402-15.
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62.
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Poritz LS, Koltun WA. Surgical management of ulcerative colitis in the presence of primary sclerosing cholangitis. Dis Colon Rectum. 2003 Feb; 46(2):173-8.
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63.
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Swenson BR, Hollenbeak CS, Koltun WA. Hospital costs and risk factors associated with complications of the ileal pouch anal anastomosis. Surgery. 2002 Oct; 132(4):767-73; discussion 773-4.
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64.
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Page MJ, Poritz LS, Kunselman SJ, Koltun WA. Factors affecting surgical risk in elderly patients with inflammatory bowel disease. J Gastrointest Surg. 2002 Jul-Aug; 6(4):606-13.
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65.
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Poritz LS, Rowe WA, Koltun WA. Remicade does not abolish the need for surgery in fistulizing Crohn's disease. Dis Colon Rectum. 2002 Jun; 45(6):771-5.
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66.
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Lin Z, deMello D, Phelps DS, Koltun WA, Page M, Floros J. Both human SP-A1 and Sp-A2 genes are expressed in small and large intestine. Pediatr Pathol Mol Med. 2001 Sep-Oct; 20(5):367-86.
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67.
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Page MJ, Poritz LS, Tilberg AF, Zhang WJ, Chorney MJ, Koltun WA. Cd1d-restricted cellular lysis by peripheral blood lymphocytes: relevance to the inflammatory bowel diseases. J Surg Res. 2000 Aug; 92(2):214-21.
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68.
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Zhang WJ, Koltun WA, Tilberg AF, Page MJ, Chorney MJ. Absence of GNAI2 codon 179 oncogene mutations in inflammatory bowel disease. Inflamm Bowel Dis. 2000 May; 6(2):103-6.
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69.
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Poritz LS, Page MJ, Tilberg AF, Koltun WA. Amelioration of graft versus host disease with anti-ICAM-1 therapy. J Surg Res. 1998 Dec; 80(2):280-6.
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70.
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Roy S, Koltun W, Chatwani A, Martens MG, Dittrich R, Luke DR. Treatment of acute gynecologic infections with trovafloxacin. Trovafloxacin Surgical Group. Am J Surg. 1998 Dec; 176(6A Suppl):67S-73S.
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71.
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Koltun WA, Tilberg AF, Page MJ, Poritz LS. Bowel permeability is improved in Crohn's disease after ileocolectomy. Dis Colon Rectum. 1998 Jun; 41(6):687-90.
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72.
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Page MJ, Dreese JC, Poritz LS, Koltun WA. Cytomegalovirus enteritis: a highly lethal condition requiring early detection and intervention. Dis Colon Rectum. 1998 May; 41(5):619-23.
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73.
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Poritz LS, Page MJ, Tilberg AF, Olt G, Ruggiero FM, Koltun WA. Monoclonal antibody to lymphocyte function associated antigen-1 improves graft-versus-host disease. Dis Colon Rectum. 1998 Mar; 41(3):299-309.
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74.
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Poritz LS, Olt GJ, Ruggiero FM, Colony P, Tilberg AF, Koltun WA. Increased LFA-1 expression in intestines of rats with GVHD after small bowel transplantation. Dig Dis Sci. 1998 Feb; 43(2):221-8.
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75.
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Christensen ND, Koltun WA, Cladel NM, Budgeon LR, Reed CA, Kreider JW, Welsh PA, Patrick SD, Yang H. Coinfection of human foreskin fragments with multiple human papillomavirus types (HPV-11, -40, and -LVX82/MM7) produces regionally separate HPV infections within the same athymic mouse xenograft. J Virol. 1997 Oct; 71(10):7337-44.
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76.
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Poritz LS, Tilberg AF, Koltun WA. Decreased expression of LFA-1 on peripheral blood lymphocytes in graft versus host disease. J Surg Res. 1997 May; 69(2):316-20.
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77.
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Sharma P, Page MJ, Poritz LS, Koltun WA, Chorney MJ. An increased gamma delta T cell population in the intestine of thymus-leukemia antigen transgenic mice. Cell Immunol. 1997 Mar 15; 176(2):153-7.
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78.
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Stephenson ER, Ilahi O, Koltun WA. Stoma creation through the stoma site: a rapid, safe technique. Dis Colon Rectum. 1997 Jan; 40(1):112-5.
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79.
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Koltun WA, Bloomer MM, Colony P, Kauffman GL. Increased intestinal permeability in rats with graft versus host disease. Gut. 1996 Aug; 39(2):291-8.
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80.
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McGarrity TJ, Peiffer LP, Neely EB, Palavarapu RG, Koltun WA, Parker P, Howett MK. Localization of protein kinase C alpha isoform expression in the human gastrointestinal tract. Cell Growth Differ. 1996 Jul; 7(7):953-9.
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81.
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Mavroidis D, Koltun WA. Technique for atraumatic delivery of intestine through the abdominal wall during stoma formation. Dis Colon Rectum. 1996 Apr; 39(4):461-2.
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82.
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Koltun WA, Bloomer MM, Tilberg AF, Seaton JF, Ilahi O, Rung G, Gifford RM, Kauffman GL. Awake epidural anesthesia is associated with improved natural killer cell cytotoxicity and a reduced stress response. Am J Surg. 1996 Jan; 171(1):68-72; discussion 72-3.
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83.
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Koltun WA, Bloomer MM, Colony PC, Ruggiero FM, Kauffman GL. Graft-versus-host disease after small bowel transplantation is associated with host colonic injury. Dig Dis Sci. 1995 Sep; 40(9):1925-33.
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84.
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Gerstle JT, Kauffman GL, Koltun WA. The incidence, management, and outcome of patients with gastrointestinal carcinoids and second primary malignancies. J Am Coll Surg. 1995 Apr; 180(4):427-32.
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85.
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Koltun WA, McKenna KJ, Rung G. Awake epidural anesthesia is effective and safe in the high-risk colectomy patient. Dis Colon Rectum. 1994 Dec; 37(12):1236-41.
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86.
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Koltun WA, Bloomer MM, Vary TC. Glutamine does not increase ammonia in systemically drained small bowel transplants. J Surg Res. 1994 Jan; 56(1):102-7.
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87.
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Koltun WA, Smith RJ, Loehner D, Durdey P, Coller JA, Murray JJ, Roberts PL, Veidenheimer MC, Schoetz DJ. Alteration in intestinal permeability after ileal pouch-anal anastomosis. Dis Colon Rectum. 1993 Oct; 36(10):922-6.
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88.
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Koltun WA, Schoetz DJ, Roberts PL, Murray JJ, Coller JA, Veidenheimer MC. Indeterminate colitis predisposes to perineal complications after ileal pouch-anal anastomosis. Dis Colon Rectum. 1991 Oct; 34(10):857-60.
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89.
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Koltun WA, Coller JA. Incarceration of colonoscope in an inguinal hernia. "Pulley" technique of removal. Dis Colon Rectum. 1991 Feb; 34(2):191-3.
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90.
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Koltun WA, Diamantstein T, Kirkman RL. Synergism between anti-interleukin 2 receptor monoclonal antibody and cyclosporine in small-intestinal transplantation. Curr Surg. 1987 Jul-Aug; 44(4):315-8.
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91.
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Koltun WA, Madara JL, Smith RJ, Kirkman RL. Metabolic aspects of small bowel transplantation in inbred rats. J Surg Res. 1987 Apr; 42(4):341-7.
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92.
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Koltun WA, Kirkman RL. Nutritional and metabolic aspects of total small bowel transplantation in inbred rats. Transplant Proc. 1987 Feb; 19(1 Pt 2):1120-2.
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