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Thomas Mcgarrity
Title Professor
Institution College of Medicine
Department Medicine
Division Gastroenterology
Address 500 University Drive Hershey PA 17033
Telephone 7175313834
Email
Background
PREFERRED TITLE/ROLE:

Physician, Professor of Medicine

EDUCATION:

Fellowship, Gastroenterology, Penn State Milton S. Hershey Medical Center (1984)
Residency, Medicine, Penn State Milton S. Hershey Medical Center (1982)
Internship, Medicine, University of Pittsburgh - University Health Center of Pittsburgh (1980)
M.D., University of Virgina, School of Medicine (1979)
Publications
1. Bhardwaj A, McGarrity TJ, Stairs DB, Mani H. Barrett's Esophagus: Emerging Knowledge and Management Strategies. Patholog Res Int. 2012; 2012:814146.
  View in: PubMed
 
2. Moole S, McGarrity TJ, Baker MJ. Screening for Familial Colorectal Cancer Risk amongst Colonoscopy Patients New to an Open-Access Endoscopy Center. ISRN Gastroenterol. 2012; 2012:152980.
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3. Mukherjee A, McGarrity TJ, Ruggiero F, Koltun W, McKenna K, Poritz L, Baker MJ. The revised Bethesda guidelines: extent of utilization in a university hospital medical center with a cancer genetics program. Hered Cancer Clin Pract. 2010; 8:9.
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4. Poynard T, Munteanu M, Colombo M, Bruix J, Schiff E, Terg R, Flamm S, Moreno-Otero R, Carrilho F, Schmidt W, Berg T, McGarrity T, Heathcote EJ, Gonçales F, Diago M, Craxi A, Silva M, Boparai N, Griffel L, Burroughs M, Brass C, Albrecht J. FibroTest is an independent predictor of virologic response in chronic hepatitis C patients retreated with pegylated interferon alfa-2b and ribavirin in the EPIC³ program. J Hepatol. 2011 Feb; 54(2):227-35.
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5. McGarrity TJ, Amos C. Less common colorectal cancer predisposition syndromes. Surg Oncol Clin N Am. 2009 Oct; 18(4):647-61.
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6. Dominic OG, McGarrity T, Dignan M, Lengerich EJ. American College of Gastroenterology Guidelines for Colorectal Cancer Screening 2008. Am J Gastroenterol. 2009 Oct; 104(10):2626-7; author reply 2628-9.
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7. Poynard T, Colombo M, Bruix J, Schiff E, Terg R, Flamm S, Moreno-Otero R, Carrilho F, Schmidt W, Berg T, McGarrity T, Heathcote EJ, Gonçales F, Diago M, Craxi A, Silva M, Bedossa P, Mukhopadhyay P, Griffel L, Burroughs M, Brass C, Albrecht J. Peginterferon alfa-2b and ribavirin: effective in patients with hepatitis C who failed interferon alfa/ribavirin therapy. Gastroenterology. 2009 May; 136(5):1618-28.e2.
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8. Woo A, Sadana A, Mauger DT, Baker MJ, Berk T, McGarrity TJ. Psychosocial impact of Peutz-Jeghers Syndrome. Fam Cancer. 2009; 8(1):59-65.
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9. Tobi M, Kam M, Ullah N, Qureshi K, Yordanova V, Hatfield J, Fligiel SE, Sochacki P, McGarrity T, Cole C, Lawson M, Jacoby R. An anti-adenoma antibody, Adnab-9, may reflect the risk for neoplastic progression in familial hamartomatous polyposis syndromes. Dig Dis Sci. 2008 Mar; 53(3):723-9.
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10. Mathew A, Peiffer LP, Rhoades K, McGarrity T. Sustained viral response to pegylated interferon alpha-2b and ribavirin in chronic hepatitis C refractory to prior treatment. Dig Dis Sci. 2006 Nov; 51(11):1956-61.
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11. McGarrity TJ, Amos C. Peutz-Jeghers syndrome: clinicopathology and molecular alterations. Cell Mol Life Sci. 2006 Sep; 63(18):2135-44.
  View in: PubMed
 
12. Mathew A, Peiffer LP, Rhoades K, McGarrity TJ. Improvement in quality of life measures in patients with refractory hepatitis C, responding to re-treatment with Pegylated interferon alpha -2b and ribavirin. Health Qual Life Outcomes. 2006; 4:30.
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13. Schreibman IR, Baker M, Amos C, McGarrity TJ. The hamartomatous polyposis syndromes: a clinical and molecular review. Am J Gastroenterol. 2005 Feb; 100(2):476-90.
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14. Amos CI, Keitheri-Cheteri MB, Sabripour M, Wei C, McGarrity TJ, Seldin MF, Nations L, Lynch PM, Fidder HH, Friedman E, Frazier ML. Genotype-phenotype correlations in Peutz-Jeghers syndrome. J Med Genet. 2004 May; 41(5):327-33.
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15. Wei C, Amos CI, Rashid A, Sabripour M, Nations L, McGarrity TJ, Frazier ML. Correlation of staining for LKB1 and COX-2 in hamartomatous polyps and carcinomas from patients with Peutz-Jeghers syndrome. J Histochem Cytochem. 2003 Dec; 51(12):1665-72.
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16. McGarrity TJ, Wagner Baker MJ, Ruggiero FM, Thiboutot DM, Hampel H, Zhou XP, Eng C. GI polyposis and glycogenic acanthosis of the esophagus associated with PTEN mutation positive Cowden syndrome in the absence of cutaneous manifestations. Am J Gastroenterol. 2003 Jun; 98(6):1429-34.
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17. McGarrity TJ, Peiffer LP, Amos CI, Frazier ML, Ward MG, Howett MK. Overexpression of cyclooxygenase 2 in hamartomatous polyps of Peutz-Jeghers syndrome. Am J Gastroenterol. 2003 Mar; 98(3):671-8.
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18. McGarrity TJ, Bhatti AM, Peters DJ, Peiffer LP, Kumar A, Inverso N. Synchronous proximal polyps and cancer in patients with polyps detected at sigmoidoscopy: results of a single, rural-based sigmoidoscopy clinic. Dig Dis Sci. 2002 Feb; 47(2):309-16.
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19. McGarrity TJ, Peiffer LP, Granville DJ, Carthy CM, Levy JG, Khandelwal M, Hunt DW. Apoptosis associated with esophageal adenocarcinoma: influence of photodynamic therapy. Cancer Lett. 2001 Feb 10; 163(1):33-41.
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20. Bhatti A, McGarrity TJ, Gabbay R. Diabetic ketoacidosis induced by alpha interferon and ribavirin treatment in a patient with hepatitis C. Am J Gastroenterol. 2001 Feb; 96(2):604-5.
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21. Peters DJ, Greene WH, Ruggiero F, McGarrity TJ. Herpes simplex-induced fulminant hepatitis in adults: a call for empiric therapy. Dig Dis Sci. 2000 Dec; 45(12):2399-404.
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22. McGarrity TJ. Barrett's oesophagus: the continuing conundrum. BMJ. 2000 Nov 18; 321(7271):1238-9.
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23. McGarrity TJ, Peters DJ, Thompson C, McGarrity SJ. Outcome of patients with chronic abdominal pain referred to chronic pain clinic. Am J Gastroenterol. 2000 Jul; 95(7):1812-6.
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24. McGarrity TJ, Ruggiero FM, Chey WY, Bajaj R, Kelly JE, Kauffman GL. Giant fundic polyp complicating attenuated familial adenomatous polyposis. Am J Gastroenterol. 2000 Jul; 95(7):1824-8.
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25. Kopreski MS, Benko FA, Borys DJ, Khan A, McGarrity TJ, Gocke CD. Somatic mutation screening: identification of individuals harboring K-ras mutations with the use of plasma DNA. J Natl Cancer Inst. 2000 Jun 7; 92(11):918-23.
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26. Gocke CD, Benko FA, Kopreski MS, McGarrity TJ. p53 and APC mutations are detectable in the plasma and serum of patients with colorectal cancer (CRC) or adenomas. Ann N Y Acad Sci. 2000 Apr; 906:44-50.
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27. McGarrity TJ, Kulin HE, Zaino RJ. Peutz-Jeghers syndrome. Am J Gastroenterol. 2000 Mar; 95(3):596-604.
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28. McGarrity TJ, Peiffer LP, Billingsley ML. Overexpression of epidermal growth factor receptor in Peutz-Jeghers syndrome. Dig Dis Sci. 1999 Jun; 44(6):1136-41.
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29. Peiffer LP, Peters DJ, McGarrity TJ. Differential effects of deoxycholic acid on proliferation of neoplastic and differentiated colonocytes in vitro. Dig Dis Sci. 1997 Nov; 42(11):2234-40.
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30. Amos CI, Bali D, Thiel TJ, Anderson JP, Gourley I, Frazier ML, Lynch PM, Luchtefeld MA, Young A, McGarrity TJ, Seldin MF. Fine mapping of a genetic locus for Peutz-Jeghers syndrome on chromosome 19p. Cancer Res. 1997 Sep 1; 57(17):3653-6.
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31. Damianos AJ, McGarrity TJ. Treatment strategies for Helicobacter pylori infection. Am Fam Physician. 1997 Jun; 55(8):2765-74, 2784-6.
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32. Zagon IS, Hytrek SD, Lang CM, Smith JP, McGarrity TJ, Wu Y, McLaughlin PJ. Opioid growth factor ([Met5]enkephalin) prevents the incidence and retards the growth of human colon cancer. Am J Physiol. 1996 Sep; 271(3 Pt 2):R780-6.
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33. Playford RJ, Hanby AM, Gschmeissner S, Peiffer LP, Wright NA, McGarrity T. The epidermal growth factor receptor (EGF-R) is present on the basolateral, but not the apical, surface of enterocytes in the human gastrointestinal tract. Gut. 1996 Aug; 39(2):262-6.
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34. Slusser SO, Liberski SM, McGarrity TJ. Survival of patients diagnosed with colorectal cancer through a television-advertised screening program. Am J Gastroenterol. 1996 Aug; 91(8):1563-6.
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35. Hytrek SD, Smith JP, McGarrity TJ, McLaughlin PJ, Lang CM, Zagon IS. Identification and characterization of zeta-opioid receptor in human colon cancer. Am J Physiol. 1996 Jul; 271(1 Pt 2):R115-21.
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36. McGarrity TJ, Peiffer LP, Neely EB, Palavarapu RG, Koltun WA, Parker P, Howett MK. Localization of protein kinase C alpha isoform expression in the human gastrointestinal tract. Cell Growth Differ. 1996 Jul; 7(7):953-9.
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37. Liberski SM, McGarrity TJ, Hartle RJ, Varano V, Reynolds D. The watermelon stomach: long-term outcome in patients treated with Nd:YAG laser therapy. Gastrointest Endosc. 1994 Sep-Oct; 40(5):584-7.
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38. McGarrity TJ, Peiffer LP. Protein kinase C activity as a potential marker for colorectal neoplasia. Dig Dis Sci. 1994 Mar; 39(3):458-63.
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39. Hartle RJ, McGarrity TJ, Conter RL. Treatment of a giant biloma and bile leak by ERCP stent placement. Am J Gastroenterol. 1993 Dec; 88(12):2117-8.
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40. McGarrity TJ, Peiffer LP. Selenium and difluoromethylornithine additively inhibit DMH-induced distal colon tumor formation in rats fed a fiber-free diet. Carcinogenesis. 1993 Nov; 14(11):2335-40.
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41. McGarrity TJ, Peiffer LP, Hartle RJ. Effect of selenium on growth, S-adenosylmethionine and polyamine biosynthesis in human colon cancer cells. Anticancer Res. 1993 May-Jun; 13(3):811-5.
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42. Jankowski J, McGarrity TJ. Screening for alimentary cancer: outstanding problems and a new strategy for research. Eur J Cancer Prev. 1993 May; 2(3):211-4.
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43. McGarrity TJ, Peiffer LP, Kramer ST, Smith JP. Effects of fat and fiber on human colon cancer xenografted to athymic nude mice. Dig Dis Sci. 1991 Nov; 36(11):1606-10.
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44. McGarrity TJ, Peiffer LP, Billingsley ML. Interspecies comparison of calmodulin binding proteins throughout the gastrointestinal tract: comparison with human colon adenomas and adenocarcinomas. Gut. 1991 Oct; 32(10):1121-6.
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45. McGarrity TJ, Peiffer LP, Colony PC. Alterations in lectin binding in the proximal and distal colon of Sprague-Dawley rats with 1,2 dimethylhydrazine administration. Exp Pathol. 1991; 41(4):175-83.
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46. McGarrity TJ, Peiffer LP, Bartholomew MJ, Pegg AE. Colonic polyamine content and ornithine decarboxylase activity as markers for adenomas. Cancer. 1990 Oct 1; 66(7):1539-43.
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47. Conter RL, Converse JO, McGarrity TJ, Koch KL. Afferent loop obstruction presenting as acute pancreatitis and pseudocyst: case reports and review of the literature. Surgery. 1990 Jul; 108(1):22-7.
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48. Foley TR, McGarrity TJ. Transient changes of dorsal pancreatic duct in acute pancreatitis associated with pancreas divisum. Dig Dis Sci. 1990 Jun; 35(6):793-7.
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49. McGarrity TJ, Long PA, Peiffer LP. Results of a repeat television-advertised mass screening program for colorectal cancer using fecal occult blood tests. Am J Gastroenterol. 1990 Mar; 85(3):266-70.
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50. McGarrity TJ, Peiffer LP, Abt AB. Lectin histochemistry of adenomatous polyps. Not a predictor of metachronous lesions. Cancer. 1989 Oct 15; 64(8):1708-13.
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51. McGarrity TJ, Long PA, Peiffer LP, Converse JO, Kreig AF. Results of a television-advertised public screening program for colorectal cancer. Arch Intern Med. 1989 Jan; 149(1):140-4.
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52. Foley TR, McGarrity TJ, Abt AB. Peutz-Jeghers syndrome: a clinicopathologic survey of the "Harrisburg family" with a 49-year follow-up. Gastroenterology. 1988 Dec; 95(6):1535-40.
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53. McGarrity TJ, Peiffer LP, Colony PC, Pegg AE. The effects of chronic ethanol administration on polyamine content during dimethylhydrazine-induced colorectal carcinogenesis in the rat. Carcinogenesis. 1988 Nov; 9(11):2093-8.
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54. McGarrity TJ, Peiffer LP, Colony PC. Cellular proliferation in proximal and distal rat colon during 1,2-dimethylhydrazine-induced carcinogenesis. Gastroenterology. 1988 Aug; 95(2):343-8.
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55. McGarrity TJ, Via EA, Colony PC. Qualitative and quantitative changes in sialomucins during 1,2-dimethylhydrazine-induced colon carcinogenesis in the rat. J Natl Cancer Inst. 1987 Dec; 79(6):1375-82.
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56. McGarrity TJ, Samuels T, Wilson FA. An analysis of imaging studies and liver function tests to detect hepatic neoplasia. Dig Dis Sci. 1987 Oct; 32(10):1113-7.
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57. McGarrity TJ, Manasse JS, Koch KL, Weidner WA. Crohn's disease and massive lower gastrointestinal bleeding: angiographic appearance and two case reports. Am J Gastroenterol. 1987 Oct; 82(10):1096-9.
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58. McGarrity TJ. Dimethylhydrazine and ethanol. Dis Colon Rectum. 1986 Apr; 29(4):289-90.
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59. McGarrity TJ, Koch KL, Rasbach DA. Refractory ascites associated with polycystic liver disease. Treatment with peritoneovenous shunt. Dig Dis Sci. 1986 Feb; 31(2):217-20.
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Keyword
Last Name
Institution
    
 
 
 
Keywords   
Peutz-Jeghers Syndrome
Colorectal Neoplasms
Colonic Neoplasms
Interferon-alpha
Ribavirin
See all (287) keywords
Co-Authors  
Abt, Arthur
Mathew, Abraham
Pegg, Anthony
Ruggiero, Francesca
Zagon, Ian
See all (20) people
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