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Berend Mets
Title Professor and Chair of Anesthesiology
Institution College of Medicine
Department Anesthesiology
Division Anesthesia Chair
Address 500 University Drive Hershey PA 17033
Telephone 7175316597
Email
Background
PREFERRED TITLE/ROLE:

Physician, Chair; Department of Anesthesiology, Eric A. Walker Professor

EDUCATION:
M.B., Ch.B., University of Stellenbosch (1980)
Internship, Edendale Hospital (1981-2)
Residency, Anesthesiology, Gloucester Royal Hospital (1984)
Residency, Anesthesiology, Groote Schuur Hospital (1985-9)
Fellow of the Royal College of Anaesthetists (1987)
Fellow of the Faculty of Anaesthetists of South Africa (1987)
PhD (Pharmacology) University of Cape Town (1992)
Diplomate of the American Board of Anesthesiology (1996)
Publications
1. Budde AO, Mets B. Pro: etomidate is the ideal induction agent for a cardiac anesthetic. J Cardiothorac Vasc Anesth. 2013 Feb; 27(1):180-3.
  View in: PubMed
 
2. Mets B. Management of hypotension associated with Angiotensin-axis blockade and general anesthesia administration. J Cardiothorac Vasc Anesth. 2013 Feb; 27(1):156-67.
  View in: PubMed
 
3. Bezinover D, Ramamoorthy S, Uemura T, Kadry Z, McQuillan PM, Mets B, Falcucci O, Rannels S, Ruiz-Velasco V, Spiess B, Liang J, Mani H, Lou X, Janicki PK. Use of a third-generation perfluorocarbon for preservation of rat DCD liver grafts. J Surg Res. 2012 Jun 1; 175(1):131-7.
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4. Steel C, Vaida S, Mets B. Case report: massive blood transfusion in a patient with immunoglobulin a deficiency undergoing cesarean delivery. Anesth Analg. 2010 Apr 1; 110(4):1088-90.
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5. Vaida S, Dalal P, Mets B. Spinal anesthesia for Cesarean delivery following pre-existing epidural labour analgesia. Can J Anaesth. 2009 Dec; 56(12):988; author reply 988-9.
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6. Mets B, Galford JA. Leadership and management of academic anesthesiology departments in the United States. J Clin Anesth. 2009 Mar; 21(2):83-93.
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7. Donahue K, Mets B. A move to universal OR start times. A case study of leading change in an academic anesthesia department. Physician Exec. 2008 Jan-Feb; 34(1):24-7.
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8. Eckert JM, Mets B. The legal background for residency training: implications for education. Int Anesthesiol Clin. 2008; 46(4):127-35.
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9. Mets B, Galford JA, Purichia HR. Leadership of United States academic anesthesiology programs 2006: chairperson characteristics and accomplishments. Anesth Analg. 2007 Nov; 105(5):1338-45, table of contents.
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10. Janicki PK, Schuler G, Francis D, Bohr A, Gordin V, Jarzembowski T, Ruiz-Velasco V, Mets B. A genetic association study of the functional A118G polymorphism of the human mu-opioid receptor gene in patients with acute and chronic pain. Anesth Analg. 2006 Oct; 103(4):1011-7.
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11. Mets B, Walker EA. Local anesthetic effect on liver function. Anesth Analg. 2006 Oct; 103(4):1045-6.
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12. Mets B, Eckerd K. Faculty incentive plans: clinical or academic productivity or both? Anesth Analg. 2006 Mar; 102(3):968-9; author reply 969-70.
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13. Kratz RD, Mets B. Finding an incentive plan that actually works. Physician Exec. 2005 May-Jun; 31(3):54-6.
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14. Sukernik MR, Frumento R, Mets B, Jordan D, Bennett-Guerrero E, Cheung AT, Chaney MA. CASE 1--2004. Intraoperative diagnosis of a patent foramen ovale in a patient undergoing coronary artery bypass graft surgery. J Cardiothorac Vasc Anesth. 2004 Feb; 18(1):101-6.
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15. O'Malley CM, Frumento RJ, Mets B, Naka Y, Bennett-Guerrero E. Endotoxaemia during left ventricular assist device insertion: relationship between risk factors and outcome. Br J Anaesth. 2004 Jan; 92(1):131-3.
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16. O'Malley CM, Frumento RJ, Mets B, Naka Y, Bennett-Guerrero E. Abnormal gastric tonometric variables and vasoconstrictor use after left ventricular assist device insertion. Ann Thorac Surg. 2003 Jun; 75(6):1886-91.
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17. Mehta N, Goswami S, Argenziano M, Smith CR, Mets B. Anesthesia for robotic repair of the mitral valve: a report of two cases. Anesth Analg. 2003 Jan; 96(1):7-10, table of contents.
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18. Mets B, Frumento RJ, Bennett-Guerrero E, Naka Y. Validation of continuous thermodilution cardiac output in patients implanted with a left ventricular assist device. J Cardiothorac Vasc Anesth. 2002 Dec; 16(6):727-30.
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19. Sukernik MR, Mets B, Kachulis B, Oz MC, Bennett-Guerrero E. The impact of newly diagnosed patent foramen ovale in patients undergoing off-pump coronary artery bypass grafting: case series of eleven patients. Anesth Analg. 2002 Nov; 95(5):1142-6, table of contents.
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20. Lehman F, Mets B, Cooper D. Magnetic resonance imaging evidence of spinal cord ischemia after coronary artery bypass graft surgery using cardiopulmonary bypass. J Cardiothorac Vasc Anesth. 2002 Oct; 16(5):664.
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21. Li Y, Khambatta HJ, Stone JG, Mets B. Unsuspected concentric tracheal rings in a 14-year-old with scoliosis. Br J Anaesth. 2002 May; 88(5):732-4.
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22. Sukernik MR, Mets B, Bennett-Guerrero E. Patent foramen ovale and its significance in the perioperative period. Anesth Analg. 2001 Nov; 93(5):1137-46.
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23. Manspeizer HE, Imai M, Frumento RJ, Parides MK, Mets B, Bennett-Guerrero E. Arterial and venous Thrombelastograph variables differ during cardiac surgery. Anesth Analg. 2001 Aug; 93(2):277-81, 1st contents page.
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24. Mets B, Reich NT, Mellas N, Beck J, Park S. Desflurane pharmacokinetics during cardiopulmonary bypass. J Cardiothorac Vasc Anesth. 2001 Apr; 15(2):179-82.
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25. Mets B, Pantuck CB, Diaz J, Soo E. The effect of chronic cocaine administration on hemodynamic stability and neurohumoral mediators during isoflurane anesthesia and shock in rats. Acta Anaesthesiol Scand. 2001 Mar; 45(3):377-84.
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26. Jamdar SC, Pantuck CB, Diaz J, Mets B. A rapid, sensitive assay for cocaine and its metabolites in biological fluids using solid-phase extraction and high-performance liquid chromatography. J Anal Toxicol. 2000 Sep; 24(6):438-41.
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27. Mets B. Anesthesia for left ventricular assist device placement. J Cardiothorac Vasc Anesth. 2000 Jun; 14(3):316-26.
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28. Mets B, Soo E, Diaz J, Pantuck C, Singh G, Blair IA. Chronic continuous cocaine infusion in rats: effect on urine cocaine, ecgonine methylester and benzoylecgonine concentrations and bolus-dose cocaine pharmacokinetics. J Pharm Pharmacol. 2000 Apr; 52(4):389-95.
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29. Mets B. The pharmacokinetics of anesthetic drugs and adjuvants during cardiopulmonary bypass. Acta Anaesthesiol Scand. 2000 Mar; 44(3):261-73.
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30. Mets B. Current status of lung volume reduction. Curr Opin Anaesthesiol. 2000 Feb; 13(1):61-4.
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31. Mets B, Ahmad S, Sherman D, Galantowitcz ME. An unusual echocardiograph after heart transplantation. J Cardiothorac Vasc Anesth. 1999 Oct; 13(5):639-40.
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32. Mets B, Jamdar S, Diaz J. Influence of infused catecholamines on the pharmacokinetics of cocaine and benzoylecgonine formation after bolus dose or continuous cocaine administration in the rat. J Pharm Pharmacol. 1999 Jun; 51(6):679-84.
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33. Mets B, Diaz J, Soo E, Jamdar S. Cocaine, norcocaine, ecgonine methylester and benzoylecgonine pharmacokinetics in the rat. Life Sci. 1999; 65(12):1317-28.
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34. Mets B, Winger G, Cabrera C, Seo S, Jamdar S, Yang G, Zhao K, Briscoe RJ, Almonte R, Woods JH, Landry DW. A catalytic antibody against cocaine prevents cocaine's reinforcing and toxic effects in rats. Proc Natl Acad Sci U S A. 1998 Aug 18; 95(17):10176-81.
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35. Mets B, Michler RE, Delphin ED, Oz MC, Landry DW. Refractory vasodilation after cardiopulmonary bypass for heart transplantation in recipients on combined amiodarone and angiotensin-converting enzyme inhibitor therapy: a role for vasopressin administration. J Cardiothorac Vasc Anesth. 1998 Jun; 12(3):326-9.
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36. Mets B, Janicki PK, James MF, Hickman R. Hepatic energy charge and adenine nucleotide status in rats anesthetized with halothane, isoflurane or enflurane. Acta Anaesthesiol Scand. 1997 Feb; 41(2):252-5.
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37. Virag L, Mets B, Jamdar S. Determination of cocaine, norcocaine, benzoylecgonine and ecgonine methyl ester in rat plasma by high-performance liquid chromatography with ultraviolet detection. J Chromatogr B Biomed Appl. 1996 Jun 7; 681(2):263-9.
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38. James MF, Hickman R, Janicki P, Mets B, Fourie J. Early effects of total hepatectomy on haemodynamic state and organ uptake of catecholamines in the pig. Br J Anaesth. 1996 May; 76(5):713-20.
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39. Mets B, Kamban JR, Janicki PK, Franks J, Neveling U, Hickman R. Alcohol pretreatment does not affect bupivacaine pharmacokinetics in the pig. Pharmacol Res. 1996 Apr-May; 33(4-5):291-5.
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40. Mets B, Jamdar S, Landry D. The role of catecholamines in cocaine toxicity: a model for cocaine "sudden death". Life Sci. 1996; 59(24):2021-31.
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41. Mets B, Virag L. Lethal toxicity from equimolar infusions of cocaine and cocaine metabolites in conscious and anesthetized rats. Anesth Analg. 1995 Nov; 81(5):1033-8.
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42. Hickman R, Stapleton GN, Mets B, Hlatshwayo S, Janicki P. Hepatic blood flow during reduced liver grafting in pigs. A comparison of controls and recipients of intact allografts. Dig Dis Sci. 1995 Jun; 40(6):1246-51.
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43. Kambam JR, Janicki PK, Franks JJ, Mets B, van der Watt M, Hickman R. Substance P level is increased in the cholesterol induced anaphylactoid reaction in the pig. Res Exp Med (Berl). 1995; 195(6):327-32.
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44. Mets B, Hickman R, Chalton D. Lidocaine extraction by the in vivo and isolated perfused pig liver. J Hepatol. 1994 Dec; 21(6):1067-74.
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45. Kambam JR, Franks JJ, Mets B, Janicki PK, Hickman R, van der Watt M. The effect of hepatectomy and plasma cholinesterase inhibition on cocaine metabolism and cardiovascular responses in pigs. J Lab Clin Med. 1994 Nov; 124(5):715-22.
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46. Kambam JR, Franks JJ, Janicki PK, Mets B, vd Watt M, Hickman R. Alcohol pretreatment alters the metabolic pattern and accelerates cocaine metabolism in pigs. Drug Alcohol Depend. 1994 Aug; 36(1):9-13.
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47. Mets B, Hickman R, Neveling U, Emms M, Chalton DO. Effect of lidocaine on in vivo hepatic function. Dig Dis Sci. 1993 Dec; 38(12):2163-9.
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48. Mets B, Broccoli E, Brown AR. Is spinal anesthesia after failed epidural anesthesia contraindicated for cesarean section? Anesth Analg. 1993 Sep; 77(3):629-31.
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49. Kambam J, Mets B, Hickman R, Janicki P, James MF, Kirsch R. The effects of inhibition of plasma cholinesterase activity on systemic toxicity and blood catecholamine levels from cocaine infusion in pigs. J Lab Clin Med. 1993 Aug; 122(2):188-96.
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50. Mets B, Hickman R, Allin R, Van Dyk J, Lotz Z. Effect of hypoxia on the hepatic metabolism of lidocaine in the isolated perfused pig liver. Hepatology. 1993 Apr; 17(4):668-76.
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51. Mets B, Allin R, van Dyke J, Hickman R. Lidocaine decay and hepatic extraction in the pig. J Vet Pharmacol Ther. 1993 Mar; 16(1):8-14.
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52. Mets B, Janicki PK, James MF, Erskine R, Sasman B. Lidocaine and bupivacaine cardiorespiratory toxicity is additive: a study in rats. Anesth Analg. 1992 Oct; 75(4):611-4.
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53. Kambam J, Mets B, Hickman RM, Janicki P, James MF, Fuller B, Kirsch RE. The effects of inhibition of plasma cholinesterase and hepatic microsomal enzyme activity on cocaine, benzoylecgonine, ecgonine methyl ester, and norcocaine blood levels in pigs. J Lab Clin Med. 1992 Aug; 120(2):323-8.
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54. Mets B. Acute dystonia after alfentanil in untreated Parkinson's disease. Anesth Analg. 1991 Apr; 72(4):557-8.
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Keyword
Last Name
Institution
    
 
 
 
Keywords   
Cocaine
Anesthesiology
Academic Medical Centers
Lidocaine
Anesthetics, Local
See all (255) keywords
Co-Authors  
Gordin, Vitaly
Janicki, Piotr
Kadry, Zakiyah
Ruiz-Velasco, Victor
Vaida, Sonia
See all (12) people
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