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Rongling Wu
Title Professor
Institution College of Medicine
Department Public Health Sciences
Address 500 University Drive Hershey PA 17033
Mailbox: A210
Telephone 7175317178
Email
Background
PREFERRED TITLE/ROLE:

Professor, Division of Biostatistics and Bioinformatics

SECONDARY APPOINTMENT(S)/ INSTITUTE(S)/ CENTER(S):

Statistics

GRADUATE PROGRAM AFFILIATIONS:

Public Health Sciences

EDUCATION:

Ph.D., University of Washington, 1995

NARRATIVE:

With a rigorous training in genetics, Dr. Wu is fascinated by the mystery of how genes can generate such a vast amount of variation in nature and what mechanistic and developmental regulation guides gene to respond to environmental signals. Dr. Wu's current research interest focuses on the development of statistical and computational methods necessary to unravel the genetic machinery of complex traits, diseases, and life processes. He is particularly interested in integrating the idea and principle of systems biology into statistical genetic research, ultimately elucidating a comprehensive atlas of the genetic control network of complex biology. He is alert and sensitive to concrete genetic or developmental problems fundamentally meaningful to agriculture, forestry, biology, and biomedicine and exceptionally good at the design of statistical models and algorithms to solve these problems. His pioneering statistical work on functional mapping was highlighted in Nature Reviews Genetics in 2004 and 2006. Dr. Wu serves Associate Editors for a number of statistical and genetic journals.
Publications
1. Wang Z, Wang Z, Wang J, Sui Y, Zhang J, Liao D, Wu R. A quantitative genetic and epigenetic model of complex traits. BMC Bioinformatics. 2012; 13:274.
  View in: PubMed
 
2. Huber-Keener KJ, Liu X, Wang Z, Wang Y, Freeman W, Wu S, Planas-Silva MD, Ren X, Cheng Y, Zhang Y, Vrana K, Liu CG, Yang JM, Wu R. Differential gene expression in tamoxifen-resistant breast cancer cells revealed by a new analytical model of RNA-Seq data. PLoS One. 2012; 7(7):e41333.
  View in: PubMed
 
3. Liao D, Shaffer ML, He F, Rodriguez-Colon S, Wu R, Whitsel EA, Bixler EO, Cascio WE. Fine particulate air pollution is associated with higher vulnerability to atrial fibrillation--the APACR study. J Toxicol Environ Health A. 2011; 74(11):693-705.
  View in: PubMed
 
4. He F, Shaffer ML, Rodriguez-Colon S, Bixler EO, Vgontzas AN, Williams RW, Wu R, Cascio WE, Liao D. Acute effects of fine particulate air pollution on ST segment height: a longitudinal study. Environ Health. 2010; 9:68.
  View in: PubMed
 
5. Berg A, He Q, Shen Y, Chen Y, Huang M, Wu R. Trilocus disequilibrium analysis of multiallelic markers in outcrossing populations. Stat Appl Genet Mol Biol. 2010; 9(1):Article 16.
  View in: PubMed
 
6. Lin Z, Nelson L, Franke A, Poritz L, Li TY, Wu R, Wang Y, MacNeill C, Thomas NJ, Schreiber S, Koltun WA. OCTN1 variant L503F is associated with familial and sporadic inflammatory bowel disease. J Crohns Colitis. 2010 Jun; 4(2):132-8.
  View in: PubMed
 
7. Lin Z, Poritz L, Franke A, Li TY, Ruether A, Byrnes KA, Wang Y, Gebhard AW, MacNeill C, Thomas NJ, Wu R, Schreiber S, Koltun WA. Genetic association of DLG5 R30Q with familial and sporadic inflammatory bowel disease in men. Dis Markers. 2009; 27(5):193-201.
  View in: PubMed
 
8. de Miranda JR, Muñoz M, Wu R, Espinoza AM. Phylogenetic placement of a novel tenuivirus from the grass Urochloa plantaginea. Virus Genes. 2001 Jun; 22(3):329-33.
  View in: PubMed
 
 
Keyword
Last Name
Institution
    
 
 
 
Keywords   
Sequence Analysis, RNA
Transcriptome
Drug Resistance, Neoplasm
Tamoxifen
Computational Biology
See all (74) keywords
Co-Authors  
Bixler, Edward
Liao, Duanping
Poritz, Lisa
Shaffer, Michele
Thomas, Neal
See all (14) people
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