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Russell Scaduto
Title Associate Professor
Institution College of Medicine
Department Cellular and Molecular Physiology
Address 500 University Drive Hershey PA 17033
Mailbox: H166
Telephone 7175316064
Email
Background
PREFERRED TITLE/ROLE:

Associate Professor of Cellular and Molecular Physiology

GRADUATE PROGRAM AFFILIATIONS:

Physiology

EDUCATION:

M.S., Physiology, Indiana University School of Medicine, 1980
Ph.D., Biochemistry, Indiana University School of Medicine, 1984
Postdoctoral Training, Pennsylvania State University College of Medicine, 1984-1986
Publications
1. DeMaio L, Antonetti DA, Scaduto RC, Gardner TW, Tarbell JM. VEGF increases paracellular transport without altering the solvent-drag reflection coefficient. Microvasc Res. 2004 Nov; 68(3):295-302.
  View in: PubMed
 
2. Ness JK, Scaduto RC, Wood TL. IGF-I prevents glutamate-mediated bax translocation and cytochrome C release in O4+ oligodendrocyte progenitors. Glia. 2004 Apr 15; 46(2):183-94.
  View in: PubMed
 
3. Scaduto RC, Grotyohann LW. Hydrolysis of Ca2+-sensitive fluorescent probes by perfused rat heart. Am J Physiol Heart Circ Physiol. 2003 Nov; 285(5):H2118-24.
  View in: PubMed
 
4. DeMaio L, Tarbell JM, Scaduto RC, Gardner TW, Antonetti DA. A transmural pressure gradient induces mechanical and biological adaptive responses in endothelial cells. Am J Physiol Heart Circ Physiol. 2004 Feb; 286(2):H731-41.
  View in: PubMed
 
5. Antonetti DA, Wolpert EB, DeMaio L, Harhaj NS, Scaduto RC. Hydrocortisone decreases retinal endothelial cell water and solute flux coincident with increased content and decreased phosphorylation of occludin. J Neurochem. 2002 Feb; 80(4):667-77.
  View in: PubMed
 
6. Scaduto RC, Grotyohann LW. 2,3-butanedione monoxime unmasks Ca(2+)-induced NADH formation and inhibits electron transport in rat hearts. Am J Physiol Heart Circ Physiol. 2000 Oct; 279(4):H1839-48.
  View in: PubMed
 
7. PiƱero DJ, Hu J, Cook BM, Scaduto RC, Connor JR. Interleukin-1beta increases binding of the iron regulatory protein and the synthesis of ferritin by increasing the labile iron pool. Biochim Biophys Acta. 2000 Sep 20; 1497(3):279-88.
  View in: PubMed
 
8. Robb SJ, Robb-Gaspers LD, Scaduto RC, Thomas AP, Connor JR. Influence of calcium and iron on cell death and mitochondrial function in oxidatively stressed astrocytes. J Neurosci Res. 1999 Mar 15; 55(6):674-86.
  View in: PubMed
 
9. Scaduto RC, Grotyohann LW. Measurement of mitochondrial membrane potential using fluorescent rhodamine derivatives. Biophys J. 1999 Jan; 76(1 Pt 1):469-77.
  View in: PubMed
 
10. Panov AV, Scaduto RC. Substrate specific effects of calcium on metabolism of rat heart mitochondria. Am J Physiol. 1996 Apr; 270(4 Pt 2):H1398-406.
  View in: PubMed
 
11. Scaduto RC. Oxidation of DMSO and methanesulfinic acid by the hydroxyl radical. Free Radic Biol Med. 1995 Feb; 18(2):271-7.
  View in: PubMed
 
12. Panov AV, Scaduto RC. Influence of calcium on NADH and succinate oxidation by rat heart submitochondrial particles. Arch Biochem Biophys. 1995 Feb 1; 316(2):815-20.
  View in: PubMed
 
13. Scaduto RC. Calcium and 2-oxoglutarate-mediated control of aspartate formation by rat heart mitochondria. Eur J Biochem. 1994 Aug 1; 223(3):751-8.
  View in: PubMed
 
14. Scott DA, Grotyohann LW, Cheung JY, Scaduto RC. Ratiometric methodology for NAD(P)H measurement in the perfused rat heart using surface fluorescence. Am J Physiol. 1994 Aug; 267(2 Pt 2):H636-44.
  View in: PubMed
 
15. Leisey JR, Scott DA, Grotyohann LW, Scaduto RC. Quantitation of myoglobin saturation in the perfused heart using myoglobin as an optical inner filter. Am J Physiol. 1994 Aug; 267(2 Pt 2):H645-53.
  View in: PubMed
 
16. Leisey JR, Grotyohann LW, Scott DA, Scaduto RC. Regulation of cardiac mitochondrial calcium by average extramitochondrial calcium. Am J Physiol. 1993 Oct; 265(4 Pt 2):H1203-8.
  View in: PubMed
 
17. Moore RL, Musch TI, Yelamarty RV, Scaduto RC, Semanchick AM, Elensky M, Cheung JY. Chronic exercise alters contractility and morphology of isolated rat cardiac myocytes. Am J Physiol. 1993 May; 264(5 Pt 1):C1180-9.
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18. Cheung JY, Elensky MB, Brauneis U, Scaduto RC, Bell LL, Tillotson DL, Miller BA. Ion channels in human erythroblasts. Modulation by erythropoietin. J Clin Invest. 1992 Nov; 90(5):1850-6.
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19. Scaduto RC, Grotyohann LW. Cysteine oxidation by the postischemic rat kidney. Am J Physiol. 1992 May; 262(5 Pt 2):F777-83.
  View in: PubMed
 
20. Scaduto RC, Gattone VH, Martin LF, Yang HC. Elevation of renal glutathione enhances ischemic injury. Ren Physiol Biochem. 1991 Nov-Dec; 14(6):259-70.
  View in: PubMed
 
21. Waybill MM, Yelamarty RV, Zhang YL, Scaduto RC, LaNoue KF, Hsu CJ, Smith BC, Tillotson DL, Yu FT, Cheung JY. Nuclear calcium gradients in cultured rat hepatocytes. Am J Physiol. 1991 Jul; 261(1 Pt 1):E49-57.
  View in: PubMed
 
22. Sterniczuk A, Hreniuk S, Scaduto RC, LaNoue KF. Effect of phenylephrine on pyruvate dehydrogenase in fasting rat livers. Eur J Biochem. 1991 Feb 26; 196(1):151-7.
  View in: PubMed
 
23. Sterniczuk A, Hreniuk S, Scaduto RC, LaNoue KF. The mechanism of Ca2(+)-related control of gluconeogenesis in perfused liver. Eur J Biochem. 1991 Feb 26; 196(1):143-50.
  View in: PubMed
 
24. Moore RL, Yelamarty RV, Misawa H, Scaduto RC, Pawlush DG, Elensky M, Cheung JY. Altered Ca2+ dynamics in single cardiac myocytes from renovascular hypertensive rats. Am J Physiol. 1991 Feb; 260(2 Pt 1):C327-37.
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25. Slusser SO, Grotyohann LW, Martin LF, Scaduto RC. Glutathione catabolism by the ischemic rat kidney. Am J Physiol. 1990 Jun; 258(6 Pt 2):F1546-53.
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26. Yelamarty RV, Miller BA, Scaduto RC, Yu FT, Tillotson DL, Cheung JY. Three-dimensional intracellular calcium gradients in single human burst-forming units-erythroid-derived erythroblasts induced by erythropoietin. J Clin Invest. 1990 Jun; 85(6):1799-809.
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27. Wan B, LaNoue KF, Cheung JY, Scaduto RC. Regulation of citric acid cycle by calcium. J Biol Chem. 1989 Aug 15; 264(23):13430-9.
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28. Cheung JY, Tillotson DL, Yelamarty RV, Scaduto RC. Cytosolic free calcium concentration in individual cardiac myocytes in primary culture. Am J Physiol. 1989 Jun; 256(6 Pt 1):C1120-30.
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29. Yang HC, Gattone VH, Martin LF, Grotyohann LW, McElroy J, Scaduto RC. The effect of glutathione content on renal function following warm ischemia. J Surg Res. 1989 Jun; 46(6):633-6.
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30. Miller BA, Cheung JY, Tillotson DL, Hope SM, Scaduto RC. Erythropoietin stimulates a rise in intracellular-free calcium concentration in single BFU-E derived erythroblasts at specific stages of differentiation. Blood. 1989 Apr; 73(5):1188-94.
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31. Scaduto RC, Gattone VH, Grotyohann LW, Wertz J, Martin LF. Effect of an altered glutathione content on renal ischemic injury. Am J Physiol. 1988 Nov; 255(5 Pt 2):F911-21.
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32. Scaduto RC. Dithiothreitol and amino acids interfere with the fluorometric determination of glutathione with orthophthaldehyde. Anal Biochem. 1988 Oct; 174(1):265-70.
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33. Miller BA, Scaduto RC, Tillotson DL, Botti JJ, Cheung JY. Erythropoietin stimulates a rise in intracellular free calcium concentration in single early human erythroid precursors. J Clin Invest. 1988 Jul; 82(1):309-15.
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34. Magovern JA, Martin LF, Pae WE, Miller CA, Answine J, Grotyohann LW, Scaduto RC. Maintenance of cardiac glutathione levels after cold ischemia. Curr Surg. 1988 Jan-Feb; 45(1):31-3.
  View in: PubMed
 
35. Scaduto RC, Davis EJ. The involvement of pyruvate cycling in the metabolism of aspartate and glycerate by the perfused rat kidney. Biochem J. 1986 Aug 1; 237(3):691-8.
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36. Scaduto RC, Schoolwerth AC. A servo-system for constant pressure perfusion of the isolated rat kidney. Am J Physiol. 1986 Apr; 250(4 Pt 2):F744-8.
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37. Scaduto RC, Schoolwerth AC. Effect of bicarbonate on glutamine and glutamate metabolism by rat kidney cortex mitochondria. Am J Physiol. 1985 Oct; 249(4 Pt 2):F573-81.
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38. Scaduto RC, Davis EJ. Serine synthesis by an isolated perfused rat kidney preparation. Biochem J. 1985 Sep 1; 230(2):303-11.
  View in: PubMed
 
39. Scaduto RC, Strzelecki T, Keyser GC, Hoover WJ, Schoolwerth AC. The effects of CO2/HCO3 on the metabolism of glutamine and glutamate by rat kidney cortex mitochondria. Contrib Nephrol. 1985; 47:180-5.
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Keyword
Last Name
Institution
    
 
 
 
Keywords   
Calcium
Mitochondria, Heart
Myocardium
Kidney
Glutathione
See all (253) keywords
Co-Authors  
Answine, Joseph
Botti, John
Lanoue, Kathryn
Miller, Barbara
Pae, Walter
See all (5) people
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