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1.
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Thomas NJ, Guardia CG, Moya FR, Cheifetz IM, Markovitz B, Cruces P, Barton P, Segal R, Simmons P, Randolph AG. A pilot, randomized, controlled clinical trial of lucinactant, a peptide-containing synthetic surfactant, in infants with acute hypoxemic respiratory failure. Pediatr Crit Care Med. 2012 Nov; 13(6):646-53.
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2.
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Willson DF, Thomas NJ, Jouvet PA. You must walk before you can run*. Pediatr Crit Care Med. 2012 Nov; 13(6):691-2.
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3.
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Khemani RG, Thomas NJ, Venkatachalam V, Scimeme JP, Berutti T, Schneider JB, Ross PA, Willson DF, Hall MW, Newth CJ. Comparison of SpO2 to PaO2 based markers of lung disease severity for children with acute lung injury. Crit Care Med. 2012 Apr; 40(4):1309-16.
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4.
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Umstead TM, Lu CJ, Freeman WM, Myers JL, Clark JB, Thomas NJ, Icitovic N, Chinchilli VM, Undar A, Phelps DS. The kinetics of cardiopulmonary bypass: a dual-platform proteomics study of plasma biomarkers in pediatric patients undergoing cardiopulmonary bypass. Artif Organs. 2012 Jan; 36(1):E1-20.
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5.
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Floros J, Londono D, Gordon D, Silveyra P, Diangelo SL, Viscardi RM, Worthen GS, Shenberger J, Wang G, Lin Z, Thomas NJ. IL-18R1 and IL-18RAP SNPs may be associated with bronchopulmonary dysplasia in African-American infants. Pediatr Res. 2012 Jan; 71(1):107-14.
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6.
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Basu RK, Standage SW, Cvijanovich NZ, Allen GL, Thomas NJ, Freishtat RJ, Anas N, Meyer K, Checchia PA, Lin R, Shanley TP, Bigham MT, Wheeler DS, Devarajan P, Goldstein SL, Wong HR. Identification of candidate serum biomarkers for severe septic shock-associated kidney injury via microarray. Crit Care. 2011; 15(6):R273.
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7.
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Wong HR, Cvijanovich NZ, Allen GL, Thomas NJ, Freishtat RJ, Anas N, Meyer K, Checchia PA, Lin R, Shanley TP, Bigham MT, Wheeler DS, Doughty LA, Tegtmeyer K, Poynter SE, Kaplan JM, Chima RS, Stalets E, Basu RK, Varisco BM, Barr FE. Validation of a gene expression-based subclassification strategy for pediatric septic shock. Crit Care Med. 2011 Nov; 39(11):2511-7.
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8.
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Floros J, Thomas NJ. Surfactant protein genetics in community-acquired pneumonia: balancing the host inflammatory state. Crit Care. 2011; 15(2):156.
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9.
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Umstead TM, Lu CJ, Freeman WM, Myers JL, Clark JB, Thomas NJ, Chinchilli VM, Vrana KE, Undar A, Phelps DS. Dual-platform proteomics study of plasma biomarkers in pediatric patients undergoing cardiopulmonary bypass. Pediatr Res. 2010 Jun; 67(6):641-9.
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10.
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Willson DF, Thomas NJ. Surfactant composition and biophysical properties are important in clinical studies. Am J Respir Crit Care Med. 2010 Apr 1; 181(7):762; author reply 762-3.
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11.
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Wang G, Guo X, Diangelo S, Thomas NJ, Floros J. Humanized SFTPA1 and SFTPA2 transgenic mice reveal functional divergence of SP-A1 and SP-A2: formation of tubular myelin in vivo requires both gene products. J Biol Chem. 2010 Apr 16; 285(16):11998-2010.
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12.
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Rooney KA, Thomas NJ. Severe pulmonary hypertension associated with the acute motor sensory axonal neuropathy subtype of Guillain-Barré syndrome. Pediatr Crit Care Med. 2010 Jan; 11(1):e16-9.
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13.
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Thomas NJ, Shaffer ML, Willson DF, Shih MC, Curley MA. Defining acute lung disease in children with the oxygenation saturation index. Pediatr Crit Care Med. 2010 Jan; 11(1):12-7.
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14.
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Undar A, Pauliks L, Clark JB, Zahn J, Rosenberg G, Kunselman AR, Sun Q, Pekkan K, Saliba K, Carney E, Thomas N, Freeman W, Vrana K, El-Banayosy A, Ural SH, Wilson R, Umstead TM, Floros J, Phelps DS, Weiss W, Snyder A, Yang S, Kimatian S, Cyran SE, Chinchilli VM, Guan Y, Rider A, Haines N, Rogerson A, Alkan-Bozkaya T, Akcevin A, Sun K, Wang S, Cun L, Myers JL. Penn State Hershey--center for pediatric cardiovascular research. Artif Organs. 2009 Nov; 33(11):883-7.
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15.
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Lin Z, Nelson L, Franke A, Poritz L, Li TY, Wu R, Wang Y, MacNeill C, Thomas NJ, Schreiber S, Koltun WA. OCTN1 variant L503F is associated with familial and sporadic inflammatory bowel disease. J Crohns Colitis. 2010 Jun; 4(2):132-8.
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16.
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Wong HR, Cvijanovich N, Lin R, Allen GL, Thomas NJ, Willson DF, Freishtat RJ, Anas N, Meyer K, Checchia PA, Monaco M, Odom K, Shanley TP. Identification of pediatric septic shock subclasses based on genome-wide expression profiling. BMC Med. 2009; 7:34.
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17.
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Thomas NJ, DiAngelo S, Hess JC, Fan R, Ball MW, Geskey JM, Willson DF, Floros J. Transmission of surfactant protein variants and haplotypes in children hospitalized with respiratory syncytial virus. Pediatr Res. 2009 Jul; 66(1):70-3.
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18.
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Lin Z, Poritz L, Franke A, Li TY, Ruether A, Byrnes KA, Wang Y, Gebhard AW, MacNeill C, Thomas NJ, Schreiber S, Koltun WA. Genetic association of nonsynonymous variants of the IL23R with familial and sporadic inflammatory bowel disease in women. Dig Dis Sci. 2010 Mar; 55(3):739-46.
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19.
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Lin Z, Poritz L, Franke A, Li TY, Ruether A, Byrnes KA, Wang Y, Gebhard AW, MacNeill C, Thomas NJ, Wu R, Schreiber S, Koltun WA. Genetic association of DLG5 R30Q with familial and sporadic inflammatory bowel disease in men. Dis Markers. 2009; 27(5):193-201.
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20.
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Tamburro RF, Thomas NJ, Pon S, Jacobs BR, Dicarlo JV, Markovitz BP, Jefferson LS, Willson DF. Post hoc analysis of calfactant use in immunocompromised children with acute lung injury: Impact and feasibility of further clinical trials. Pediatr Crit Care Med. 2008 Sep; 9(5):459-64.
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21.
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Lull ME, Carkaci-Salli N, Freeman WM, Myers JL, Midgley FM, Thomas NJ, Kimatian SJ, Vrana KE, Undar A. Plasma biomarkers in pediatric patients undergoing cardiopulmonary bypass. Pediatr Res. 2008 Jun; 63(6):638-44.
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22.
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Kesler H, Dias MS, Shaffer M, Rottmund C, Cappos K, Thomas NJ. Demographics of abusive head trauma in the Commonwealth of Pennsylvania. J Neurosurg Pediatr. 2008 May; 1(5):351-6.
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23.
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Bateman ST, Lacroix J, Boven K, Forbes P, Barton R, Thomas NJ, Jacobs B, Markovitz B, Goldstein B, Hanson JH, Li HA, Randolph AG. Anemia, blood loss, and blood transfusions in North American children in the intensive care unit. Am J Respir Crit Care Med. 2008 Jul 1; 178(1):26-33.
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24.
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Thomas NJ, Ramnarayan P, Bell MJ, Maheshwari P, Wilson S, Nazarian EB, Phipps LM, Stockwell DC, Engel M, Maffei FA, Vyas HG, Britto J. An international assessment of a web-based diagnostic tool in critically ill children. Technol Health Care. 2008; 16(2):103-10.
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25.
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Geskey JM, Thomas NJ, Brummel GL. Palivizumab in congenital heart disease: should international guidelines be revised? Expert Opin Biol Ther. 2007 Nov; 7(11):1615-20.
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26.
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Thomas NJ, Shaffer ML, Rzucidlo S, Shirk BJ, Dias MS. Temporal factors and the incidence of physical abuse in young children: decreased nonaccidental trauma during Child Abuse Prevention Month. J Pediatr Surg. 2007 Oct; 42(10):1735-9.
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27.
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Lin Z, Thomas NJ, Bibikova M, Seifart C, Wang Y, Guo X, Wang G, Vollmer E, Goldmann T, Garcia EW, Zhou L, Fan JB, Floros J. DNA methylation markers of surfactant proteins in lung cancer. Int J Oncol. 2007 Jul; 31(1):181-91.
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28.
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Thomas NJ, Fan R, Diangelo S, Hess JC, Floros J. Haplotypes of the surfactant protein genes A and D as susceptibility factors for the development of respiratory distress syndrome. Acta Paediatr. 2007 Jul; 96(7):985-9.
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29.
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Phipps LM, Bartke CN, Spear DA, Jones LF, Foerster CP, Killian ME, Hughes JR, Hess JC, Johnson DR, Thomas NJ. Assessment of parental presence during bedside pediatric intensive care unit rounds: effect on duration, teaching, and privacy. Pediatr Crit Care Med. 2007 May; 8(3):220-4.
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30.
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Phipps LM, Thomas NJ. The use of a daily goals sheet to improve communication in the paediatric intensive care unit. Intensive Crit Care Nurs. 2007 Oct; 23(5):264-71.
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31.
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Thomas NJ, Hollenbeak CS, Ceneviva GD, Geskey JM, Young MJ. Palivizumab prophylaxis to prevent respiratory syncytial virus mortality after pediatric bone marrow transplantation: a decision analysis model. J Pediatr Hematol Oncol. 2007 Apr; 29(4):227-32.
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32.
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Wong HR, Shanley TP, Sakthivel B, Cvijanovich N, Lin R, Allen GL, Thomas NJ, Doctor A, Kalyanaraman M, Tofil NM, Penfil S, Monaco M, Tagavilla MA, Odoms K, Dunsmore K, Barnes M, Aronow BJ. Genome-level expression profiles in pediatric septic shock indicate a role for altered zinc homeostasis in poor outcome. Physiol Genomics. 2007 Jul 18; 30(2):146-55.
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33.
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Geskey JM, Thomas NJ, Brummel GL. Palivizumab: a review of its use in the protection of high risk infants against respiratory syncytial virus (RSV). Biologics. 2007 Mar; 1(1):33-43.
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34.
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Mikerov AN, Wang G, Umstead TM, Zacharatos M, Thomas NJ, Phelps DS, Floros J. Surfactant protein A2 (SP-A2) variants expressed in CHO cells stimulate phagocytosis of Pseudomonas aeruginosa more than do SP-A1 variants. Infect Immun. 2007 Mar; 75(3):1403-12.
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35.
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Shore PM, Berger RP, Varma S, Janesko KL, Wisniewski SR, Clark RS, Adelson PD, Thomas NJ, Lai YC, Bayir H, Kochanek PM. Cerebrospinal fluid biomarkers versus glasgow coma scale and glasgow outcome scale in pediatric traumatic brain injury: the role of young age and inflicted injury. J Neurotrauma. 2007 Jan; 24(1):75-86.
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36.
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Tagaram HR, Wang G, Umstead TM, Mikerov AN, Thomas NJ, Graff GR, Hess JC, Thomassen MJ, Kavuru MS, Phelps DS, Floros J. Characterization of a human surfactant protein A1 (SP-A1) gene-specific antibody; SP-A1 content variation among individuals of varying age and pulmonary health. Am J Physiol Lung Cell Mol Physiol. 2007 May; 292(5):L1052-63.
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37.
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Thomas NJ, Tamburro RF. Opioids causing a back up in the pediatric intensive care unit? No solution yet. Pediatr Crit Care Med. 2006 May; 7(3):287-8.
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38.
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Floros J, Thomas NJ, Liu W, Papagaroufalis C, Xanthou M, Pereira S, Fan R, Guo X, Diangelo S, Pavlovic J. Family-based association tests suggest linkage between surfactant protein B (SP-B) (and flanking region) and respiratory distress syndrome (RDS): SP-B haplotypes and alleles from SP-B-linked loci are risk factors for RDS. Pediatr Res. 2006 Apr; 59(4 Pt 1):616-21.
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39.
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Mart CR, Parrish M, Rosen KL, Dettorre MD, Ceneviva GD, Lucking SE, Thomas NJ. Safety and efficacy of sedation with propofol for transoesophageal echocardiography in children in an outpatient setting. Cardiol Young. 2006 Apr; 16(2):152-6.
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40.
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Vitale MA, Rzucidlo S, Shaffer ML, Ceneviva GD, Thomas NJ. The impact of pediatric trauma in the Amish community. J Pediatr. 2006 Mar; 148(3):359-65.
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41.
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Bibikova M, Lin Z, Zhou L, Chudin E, Garcia EW, Wu B, Doucet D, Thomas NJ, Wang Y, Vollmer E, Goldmann T, Seifart C, Jiang W, Barker DL, Chee MS, Floros J, Fan JB. High-throughput DNA methylation profiling using universal bead arrays. Genome Res. 2006 Mar; 16(3):383-93.
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42.
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Pavlovic J, Papagaroufalis C, Xanthou M, Liu W, Fan R, Thomas NJ, Apostolidou I, Papathoma E, Megaloyianni E, DiAngelo S, Floros J. Genetic variants of surfactant proteins A, B, C, and D in bronchopulmonary dysplasia. Dis Markers. 2006; 22(5-6):277-91.
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43.
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Salib EA, Cyran SE, Cilley RE, Maron BJ, Thomas NJ. Efficacy of bystander cardiopulmonary resuscitation and out-of-hospital automated external defibrillation as life-saving therapy in commotio cordis. J Pediatr. 2005 Dec; 147(6):863-6.
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44.
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Phipps LM, Weber MD, Ginder BR, Hulse MA, Thomas NJ. A randomized controlled trial comparing three different techniques of nasojejunal feeding tube placement in critically ill children. JPEN J Parenter Enteral Nutr. 2005 Nov-Dec; 29(6):420-4.
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45.
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Kelly RB, Porter PA, Meier AH, Myers JL, Thomas NJ. Duration of cardiopulmonary resuscitation before extracorporeal rescue: how long is not long enough? ASAIO J. 2005 Sep-Oct; 51(5):665-7.
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46.
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Phipps LM, Thomas NJ, Gilmore RK, Raymond JA, Bittner TR, Orr RA, Robertson CL. Prospective assessment of guidelines for determining appropriate depth of endotracheal tube placement in children. Pediatr Crit Care Med. 2005 Sep; 6(5):519-22.
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47.
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Zaidi AN, Dettorre MD, Ceneviva GD, Thomas NJ. Epoprostenol and home mechanical ventilation for pulmonary hypertension associated with chronic lung disease. Pediatr Pulmonol. 2005 Sep; 40(3):265-9.
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48.
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Lin Z, Thomas NJ, Wang Y, Guo X, Seifart C, Shakoor H, Floros J. Deletions within a CA-repeat-rich region of intron 4 of the human SP-B gene affect mRNA splicing. Biochem J. 2005 Jul 15; 389(Pt 2):403-12.
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49.
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Zaidi AN, Ceneviva GD, Phipps LM, Dettorre MD, Mart CR, Thomas NJ. Myocardial calcification caused by secondary hyperparathyroidism due to dietary deficiency of calcium and vitamin D. Pediatr Cardiol. 2005 Jul-Aug; 26(4):460-3.
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50.
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Downs LA, Thomas NJ, Comito MA, Meier AH, Dias MS. Idiopathic thrombocytopenic purpura complicated by an intracranial hemorrhage secondary to an arteriovenous malformation. Pediatr Emerg Care. 2005 May; 21(5):309-11.
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51.
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Thomas NJ, Umstead TM, Phelps DS. Altered chemokine response in an animal model of multiple organ dysfunction syndrome induced by zymosan. J Pediatr Surg. 2005 Mar; 40(3):464-9.
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52.
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Thomas NJ, Hollenbeak CS, Lucking SE, Willson DF. Cost-effectiveness of exogenous surfactant therapy in pediatric patients with acute hypoxemic respiratory failure. Pediatr Crit Care Med. 2005 Mar; 6(2):160-5.
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53.
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Willson DF, Thomas NJ, Markovitz BP, Bauman LA, DiCarlo JV, Pon S, Jacobs BR, Jefferson LS, Conaway MR, Egan EA. Effect of exogenous surfactant (calfactant) in pediatric acute lung injury: a randomized controlled trial. JAMA. 2005 Jan 26; 293(4):470-6.
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54.
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Thomas NJ, Messina JJ, DeBruin WJ, Carcillo JA. Cardiac failure in hemolytic uremic syndrome and rescue with extracorporeal life support. Pediatr Cardiol. 2005 Jan-Feb; 26(1):104-6.
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55.
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Shore PM, Thomas NJ, Clark RS, Adelson PD, Wisniewski SR, Janesko KL, Bayir H, Jackson EK, Kochanek PM. Continuous versus intermittent cerebrospinal fluid drainage after severe traumatic brain injury in children: effect on biochemical markers. J Neurotrauma. 2004 Sep; 21(9):1113-22.
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56.
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Berger RP, Heyes MP, Wisniewski SR, Adelson PD, Thomas N, Kochanek PM. Assessment of the macrophage marker quinolinic acid in cerebrospinal fluid after pediatric traumatic brain injury: insight into the timing and severity of injury in child abuse. J Neurotrauma. 2004 Sep; 21(9):1123-30.
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57.
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Temple AM, Thomas NJ. Gas gangrene secondary to Clostridium perfringens in pediatric oncology patients. Pediatr Emerg Care. 2004 Jul; 20(7):457-9.
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58.
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Levi BH, Thomas NJ, Green MJ, Rentmeester CA, Ceneviva GD. Jading in the pediatric intensive care unit: Implications for healthcare providers of medically complex children. Pediatr Crit Care Med. 2004 May; 5(3):275-7.
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59.
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Geskey JM, Thomas NJ. Amantadine penetration into cerebrospinal fluid of a child with influenza A encephalitis. Pediatr Infect Dis J. 2004 Mar; 23(3):270-2.
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60.
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Popernack ML, Thomas NJ, Lucking SE. Decreasing unplanned extubations: utilization of the Penn State Children's Hospital Sedation Algorithm. Pediatr Crit Care Med. 2004 Jan; 5(1):58-62.
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61.
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Ceneviva GD, Thomas NJ, Kees-Folts D. Magnesium sulfate for control of muscle rigidity and spasms and avoidance of mechanical ventilation in pediatric tetanus. Pediatr Crit Care Med. 2003 Oct; 4(4):480-4.
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62.
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Varma S, Janesko KL, Wisniewski SR, Bayir H, Adelson PD, Thomas NJ, Kochanek PM. F2-isoprostane and neuron-specific enolase in cerebrospinal fluid after severe traumatic brain injury in infants and children. J Neurotrauma. 2003 Aug; 20(8):781-6.
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63.
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Thomas NJ, Carcillo JA. Theophylline for acute renal vasoconstriction associated with tacrolimus: a new indication for an old therapeutic agent? Pediatr Crit Care Med. 2003 Jul; 4(3):392-3.
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64.
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Thomas NJ, Lucking SE, Dillon PW, Cilley RE. Is the injured child different or just treated differently with respect to the development of multiple organ dysfunction syndrome? J Trauma. 2003 Jul; 55(1):181-2; author repy 183-4.
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65.
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Thomas NJ, Carcillo JA, Herzer WA, Mi Z, Tofovic SP, Jackson EK. Type IV phosphodiesterase inhibition improves cardiac contractility in endotoxemic rats. Eur J Pharmacol. 2003 Mar 28; 465(1-2):133-9.
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66.
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Khandelwal P, Bohn D, Carcillo JA, Thomas NJ. Pro/con clinical debate: do colloids have advantages over crystalloids in paediatric sepsis? Crit Care. 2002 Aug; 6(4):286-8.
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67.
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Thomas NJ, Carcillo JA, Doughty LA, Sasser H, Heine RP. Plasma concentrations of defensins and lactoferrin in children with severe sepsis. Pediatr Infect Dis J. 2002 Jan; 21(1):34-8.
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68.
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Thomas NJ, Carcillo JA, Herzer WA, Mi Z, Jackson EK. Chronic type IV phosphodiesterase inhibition protects glomerular filtration rate and renal and mesenteric blood flow in a zymosan-induced model of multiple organ dysfunction syndrome treated with norepinephrine. J Pharmacol Exp Ther. 2001 Jan; 296(1):168-74.
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69.
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Herzer WA, Thomas NJ, Carcillo JA, Tofovic SP, Jackson EK. Effects of type IV phosphodiesterase inhibition on cardiac function in the presence and absence of catecholamines. J Cardiovasc Pharmacol. 1998 Nov; 32(5):769-76.
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70.
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Thomas NJ, Herzer WA, Carcillo JA, Jackson EK. Effect of the type IV phosphodiesterase inhibitor Ro 20-1724 on catecholamine-induced alterations in regional vascular resistance and regional blood flow. J Cardiovasc Pharmacol. 1998 Jun; 31(6):840-53.
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71.
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Thomas NJ, Carcillo JA. Hypovolemic shock in pediatric patients. New Horiz. 1998 May; 6(2):120-9.
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72.
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Tecklenburg FW, Thomas NJ, Webb SA, Case C, Habib DM. Pediatric ECMO for severe quinidine cardiotoxicity. Pediatr Emerg Care. 1997 Apr; 13(2):111-3.
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73.
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Carcillo JA, Herzer WA, Mi Z, Thomas NJ, Jackson EK. Treatment with the type IV phosphodiesterase inhibitor Ro 20-1724 protects renal and mesenteric blood flow in endotoxemic rats treated with norepinephrine. J Pharmacol Exp Ther. 1996 Dec; 279(3):1197-204.
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74.
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Thomas NJ, Key JD, Ector WL. Bicycle-related head injuries in South Carolina children: what can we do to prevent them? J S C Med Assoc. 1994 Aug; 90(8):355-9.
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